FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6561, 374 aa
1>>>pF1KB6561 374 - 374 aa - 374 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3303+/-0.000354; mu= 11.9804+/- 0.022
mean_var=104.4696+/-21.617, 0's: 0 Z-trim(115.5): 183 B-trim: 443 in 1/54
Lambda= 0.125481
statistics sampled from 25779 (26013) to 25779 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.305), width: 16
Scan time: 7.850
The best scores are: opt bits E(85289)
NP_000557 (OMIM: 146760) high affinity immunoglobu ( 374) 2507 464.5 1.7e-130
XP_005245014 (OMIM: 146760) PREDICTED: high affini ( 375) 2495 462.4 7.8e-130
XP_005245015 (OMIM: 146760) PREDICTED: high affini ( 282) 1815 339.2 7.1e-93
NP_001231839 (OMIM: 601502) high affinity immunogl ( 224) 1482 278.8 8.3e-75
NP_001017986 (OMIM: 601502) high affinity immunogl ( 280) 1264 239.4 7.6e-63
XP_016856150 (OMIM: 601502) PREDICTED: high affini ( 281) 1251 237.1 3.9e-62
NP_001002901 (OMIM: 609251) Fc receptor-like B iso ( 426) 654 129.1 1.8e-29
NP_001307170 (OMIM: 609251) Fc receptor-like B iso ( 426) 654 129.1 1.8e-29
NP_001004340 (OMIM: 601502) high affinity immunogl ( 188) 640 126.3 5.6e-29
XP_016856151 (OMIM: 601502) PREDICTED: high affini ( 195) 640 126.3 5.7e-29
NP_001257964 (OMIM: 610665) low affinity immunoglo ( 268) 598 118.8 1.4e-26
NP_001121068 (OMIM: 146740,615707) low affinity im ( 253) 590 117.4 3.7e-26
NP_001121064 (OMIM: 146740,615707) low affinity im ( 358) 590 117.5 4.9e-26
NP_000561 (OMIM: 610665) low affinity immunoglobul ( 233) 586 116.6 5.8e-26
NP_001231682 (OMIM: 610665) low affinity immunoglo ( 269) 586 116.7 6.5e-26
XP_016856157 (OMIM: 146790,152700,611162) PREDICTE ( 275) 584 116.3 8.5e-26
NP_001121065 (OMIM: 146740,615707) low affinity im ( 254) 578 115.2 1.7e-25
NP_001316049 (OMIM: 146740,615707) low affinity im ( 254) 578 115.2 1.7e-25
NP_001121067 (OMIM: 146740,615707) low affinity im ( 254) 578 115.2 1.7e-25
NP_000560 (OMIM: 146740,615707) low affinity immun ( 359) 578 115.3 2.2e-25
NP_067674 (OMIM: 146790,152700,611162) low affinit ( 316) 575 114.7 2.9e-25
NP_001257965 (OMIM: 610665) low affinity immunoglo ( 216) 572 114.1 3.2e-25
NP_001002275 (OMIM: 152700,604590,611162) low affi ( 309) 574 114.5 3.3e-25
XP_016856152 (OMIM: 146790,152700,611162) PREDICTE ( 368) 575 114.8 3.3e-25
XP_016856159 (OMIM: 152700,604590,611162) PREDICTE ( 323) 574 114.6 3.4e-25
XP_016856156 (OMIM: 146790,152700,611162) PREDICTE ( 276) 573 114.3 3.4e-25
XP_016856155 (OMIM: 146790,152700,611162) PREDICTE ( 328) 573 114.4 3.9e-25
XP_011508335 (OMIM: 605877) PREDICTED: Fc receptor ( 844) 575 115.0 6.4e-25
NP_001002273 (OMIM: 152700,604590,611162) low affi ( 290) 568 113.4 6.6e-25
XP_011508334 (OMIM: 605877) PREDICTED: Fc receptor ( 884) 575 115.0 6.6e-25
XP_011508333 (OMIM: 605877) PREDICTED: Fc receptor ( 884) 575 115.0 6.6e-25
NP_112571 (OMIM: 605877) Fc receptor-like protein ( 977) 575 115.1 7.2e-25
NP_001182317 (OMIM: 605877) Fc receptor-like prote ( 998) 575 115.1 7.3e-25
NP_001177757 (OMIM: 152700,604590,611162) low affi ( 303) 565 112.9 1e-24
XP_011507593 (OMIM: 146790,152700,611162) PREDICTE ( 261) 564 112.7 1e-24
NP_003992 (OMIM: 152700,604590,611162) low affinit ( 310) 565 112.9 1e-24
XP_016856160 (OMIM: 152700,604590,611162) PREDICTE ( 310) 565 112.9 1e-24
XP_016856158 (OMIM: 152700,604590,611162) PREDICTE ( 324) 565 112.9 1.1e-24
NP_001129691 (OMIM: 146790,152700,611162) low affi ( 317) 564 112.7 1.2e-24
XP_011507592 (OMIM: 146790,152700,611162) PREDICTE ( 317) 564 112.7 1.2e-24
XP_016856154 (OMIM: 146790,152700,611162) PREDICTE ( 353) 564 112.8 1.3e-24
XP_016856153 (OMIM: 146790,152700,611162) PREDICTE ( 353) 564 112.8 1.3e-24
XP_011507589 (OMIM: 146790,152700,611162) PREDICTE ( 369) 564 112.8 1.3e-24
XP_011508336 (OMIM: 605876) PREDICTED: Fc receptor ( 514) 563 112.7 1.9e-24
XP_016856161 (OMIM: 152700,604590,611162) PREDICTE ( 291) 559 111.8 2e-24
NP_001002274 (OMIM: 152700,604590,611162) low affi ( 291) 559 111.8 2e-24
XP_011507594 (OMIM: 152700,604590,611162) PREDICTE ( 234) 552 110.5 4.1e-24
NP_112572 (OMIM: 605876) Fc receptor-like protein ( 515) 553 110.9 6.8e-24
NP_963857 (OMIM: 188030,612169) low affinity immun ( 323) 548 109.8 8.8e-24
XP_011508366 (OMIM: 606891) PREDICTED: Fc receptor ( 364) 515 103.9 6.1e-22
>>NP_000557 (OMIM: 146760) high affinity immunoglobulin (374 aa)
initn: 2507 init1: 2507 opt: 2507 Z-score: 2463.6 bits: 464.5 E(85289): 1.7e-130
Smith-Waterman score: 2507; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KB6 MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 ISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQ
310 320 330 340 350 360
370
pF1KB6 LQEGVHRKEPQGAT
::::::::::::::
NP_000 LQEGVHRKEPQGAT
370
>>XP_005245014 (OMIM: 146760) PREDICTED: high affinity i (375 aa)
initn: 2389 init1: 2389 opt: 2495 Z-score: 2451.9 bits: 462.4 E(85289): 7.8e-130
Smith-Waterman score: 2495; 99.7% identity (99.7% similar) in 375 aa overlap (1-374:1-375)
10 20 30 40 50
pF1KB6 MWFLTTLLLWVPVDGQV-DTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLN
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_005 MWFLTTLLLWVPVDGQVVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 GTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 GISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 NTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 GIMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEE
310 320 330 340 350 360
360 370
pF1KB6 QLQEGVHRKEPQGAT
:::::::::::::::
XP_005 QLQEGVHRKEPQGAT
370
>>XP_005245015 (OMIM: 146760) PREDICTED: high affinity i (282 aa)
initn: 1876 init1: 1815 opt: 1815 Z-score: 1788.3 bits: 339.2 E(85289): 7.1e-93
Smith-Waterman score: 1815; 100.0% identity (100.0% similar) in 272 aa overlap (103-374:11-282)
80 90 100 110 120 130
pF1KB6 TSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPLALRCHAWKDKLV
::::::::::::::::::::::::::::::
XP_005 MWFLTTLLLWGWLLLQVSSRVFTEGEPLALRCHAWKDKLV
10 20 30 40
140 150 160 170 180 190
pF1KB6 YNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGISVTVKELFPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGISVTVKELFPAP
50 60 70 80 90 100
200 210 220 230 240 250
pF1KB6 VLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRNTSSEYQILTARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRNTSSEYQILTARR
110 120 130 140 150 160
260 270 280 290 300 310
pF1KB6 EDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVGIMFLVNTVLWVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVGIMFLVNTVLWVT
170 180 190 200 210 220
320 330 340 350 360 370
pF1KB6 IRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQLQEGVHRKEPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQLQEGVHRKEPQG
230 240 250 260 270 280
pF1KB6 AT
::
XP_005 AT
>>NP_001231839 (OMIM: 601502) high affinity immunoglobul (224 aa)
initn: 1481 init1: 1245 opt: 1482 Z-score: 1464.0 bits: 278.8 E(85289): 8.3e-75
Smith-Waterman score: 1482; 98.7% identity (98.7% similar) in 224 aa overlap (1-223:1-224)
10 20 30 40 50 60
pF1KB6 MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_001 TATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFMEGEPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAG
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 IS-VTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGR
:: ::::::::::::::::::::::::::::::::::::::::
NP_001 ISQYTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGL
190 200 210 220
240 250 260 270 280 290
pF1KB6 NTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAV
>>NP_001017986 (OMIM: 601502) high affinity immunoglobul (280 aa)
initn: 1849 init1: 1245 opt: 1264 Z-score: 1249.3 bits: 239.4 E(85289): 7.6e-63
Smith-Waterman score: 1665; 73.3% identity (73.8% similar) in 374 aa overlap (1-374:1-280)
10 20 30 40 50 60
pF1KB6 MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_001 TATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFMEGEPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 ISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRN
::
NP_001 IS----------------------------------------------------------
250 260 270 280 290 300
pF1KB6 TSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVG
. : :::::::::::::::::::
NP_001 ------------------------------------QYTVKGLQLPTPVWFHVLFYLAVG
190 200
310 320 330 340 350 360
pF1KB6 IMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQ
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 IMFLVNTVLWVTIRKELKRKKKWNLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQ
210 220 230 240 250 260
370
pF1KB6 LQEGVHRKEPQGAT
::::::::::::::
NP_001 LQEGVHRKEPQGAT
270 280
>>XP_016856150 (OMIM: 601502) PREDICTED: high affinity i (281 aa)
initn: 1730 init1: 1126 opt: 1251 Z-score: 1236.6 bits: 237.1 E(85289): 3.9e-62
Smith-Waterman score: 1652; 72.8% identity (73.6% similar) in 375 aa overlap (1-374:1-281)
10 20 30 40 50
pF1KB6 MWFLTTLLLWVPVDGQV-DTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLN
::::::::::::::::: :::::::::::::::::::::.::::::::::::::::::::
XP_016 MWFLTTLLLWVPVDGQVVDTTKAVITLQPPWVSVFQEETITLHCEVLHLPGSSSTQWFLN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 GTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 GTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFMEGEP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 GISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGR
:::
XP_016 GIS---------------------------------------------------------
240 250 260 270 280 290
pF1KB6 NTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAV
. : ::::::::::::::::::
XP_016 -------------------------------------QYTVKGLQLPTPVWFHVLFYLAV
190 200
300 310 320 330 340 350
pF1KB6 GIMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEE
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
XP_016 GIMFLVNTVLWVTIRKELKRKKKWNLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEE
210 220 230 240 250 260
360 370
pF1KB6 QLQEGVHRKEPQGAT
:::::::::::::::
XP_016 QLQEGVHRKEPQGAT
270 280
>>NP_001002901 (OMIM: 609251) Fc receptor-like B isoform (426 aa)
initn: 490 init1: 327 opt: 654 Z-score: 649.9 bits: 129.1 E(85289): 1.8e-29
Smith-Waterman score: 654; 40.5% identity (62.5% similar) in 291 aa overlap (1-278:1-285)
10 20 30 40 50
pF1KB6 MWFLTTLLLWVPVDGQVDTT-KAVITLQPPWVSVFQEETVTLHCEVLHLP-----GSSST
:: ::.::: :: .::. : : ...:.:::...:. : :::.:. : : ::
NP_001 MWPLTALLLLVPSSGQAATLEKPILSLHPPWTTIFKGERVTLKCDGYH-PLLLELQPIST
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 QWFLNGTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVF
:.:. . ::.. : :. : :::: . ::::.: . ::.:::
NP_001 LWYLG----HLLLPSHK-KSIEVQTPGVYRCQTRGAPVSDPIHLSVSNDWLILQVPYAPV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 TEGEPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGK-
:::::.:::..: ::.::.. ::..:.: ..:: ..: :.:.. : .: :.::: .
NP_001 FEGEPLVLRCRGWYDKVVYKLHYYHDGQAVRYFHSSANYTVLQARASDSGRYQCSGTMRI
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 ----HRYTSAGISVTVKELFPAPVLNASVTSPLLEGNL--VTLSCETKLLLQRPGLQLYF
. :: ..:::.::: :::: . . : :.: :.:.: :. : :
NP_001 PVESAPMFSAKVAVTVQELFRAPVLRVMGPREARGAALGGVVLRCDTRLHPQKRDTPLQF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 SFYMGSKTLRGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPT
.:: :...: . ..:: . . :. ::::::: .: :::: :.:
NP_001 AFYKYSRAVRRFDWGAEYTVPEPEVEELESYWCEAATATRSVRKRSPWLQLPGPGSPLDP
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB6 PVWFHVLFYLAVGIMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHL
NP_001 ASTTAPAPWAAALAPGNRPLSFRKPPVSRSVPLVTSVRNTTSTGLQFPASGAPTAGPPAC
300 310 320 330 340 350
>>NP_001307170 (OMIM: 609251) Fc receptor-like B isoform (426 aa)
initn: 490 init1: 327 opt: 654 Z-score: 649.9 bits: 129.1 E(85289): 1.8e-29
Smith-Waterman score: 654; 40.5% identity (62.5% similar) in 291 aa overlap (1-278:1-285)
10 20 30 40 50
pF1KB6 MWFLTTLLLWVPVDGQVDTT-KAVITLQPPWVSVFQEETVTLHCEVLHLP-----GSSST
:: ::.::: :: .::. : : ...:.:::...:. : :::.:. : : ::
NP_001 MWPLTALLLLVPSSGQAATLEKPILSLHPPWTTIFKGERVTLKCDGYH-PLLLELQPIST
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 QWFLNGTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVF
:.:. . ::.. : :. : :::: . ::::.: . ::.:::
NP_001 LWYLG----HLLLPSHK-KSIEVQTPGVYRCQTRGAPVSDPIHLSVSNDWLILQVPYAPV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 TEGEPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGK-
:::::.:::..: ::.::.. ::..:.: ..:: ..: :.:.. : .: :.::: .
NP_001 FEGEPLVLRCRGWYDKVVYKLHYYHDGQAVRYFHSSANYTVLQARASDSGRYQCSGTMRI
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 ----HRYTSAGISVTVKELFPAPVLNASVTSPLLEGNL--VTLSCETKLLLQRPGLQLYF
. :: ..:::.::: :::: . . : :.: :.:.: :. : :
NP_001 PVESAPMFSAKVAVTVQELFRAPVLRVMGPREARGAALGGVVLRCDTRLHPQKRDTPLQF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 SFYMGSKTLRGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPT
.:: :...: . ..:: . . :. ::::::: .: :::: :.:
NP_001 AFYKYSRAVRRFDWGAEYTVPEPEVEELESYWCEAATATRSVRKRSPWLQLPGPGSPLDP
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB6 PVWFHVLFYLAVGIMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHL
NP_001 ASTTAPAPWAAALAPGNRPLSFRKPPVSRSVPLVTSVRNTTSTGLQFPASGAPTAGPPAC
300 310 320 330 340 350
>>NP_001004340 (OMIM: 601502) high affinity immunoglobul (188 aa)
initn: 1218 init1: 618 opt: 640 Z-score: 641.3 bits: 126.3 E(85289): 5.6e-29
Smith-Waterman score: 973; 63.2% identity (64.0% similar) in 272 aa overlap (103-374:11-188)
80 90 100 110 120 130
pF1KB6 TSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPLALRCHAWKDKLV
:::::::::::: :::::::::::::::::
NP_001 MWFLTTLLLWGWLLLQVSSRVFMEGEPLALRCHAWKDKLV
10 20 30 40
140 150 160 170 180 190
pF1KB6 YNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGISVTVKELFPAP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGIS----------
50 60 70 80 90
200 210 220 230 240 250
pF1KB6 VLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRNTSSEYQILTARR
NP_001 ------------------------------------------------------------
260 270 280 290 300 310
pF1KB6 EDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVGIMFLVNTVLWVT
. : :::::::::::::::::::::::::::::::
NP_001 ------------------------QYTVKGLQLPTPVWFHVLFYLAVGIMFLVNTVLWVT
100 110 120
320 330 340 350 360 370
pF1KB6 IRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQLQEGVHRKEPQG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRKELKRKKKWNLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQLQEGVHRKEPQG
130 140 150 160 170 180
pF1KB6 AT
::
NP_001 AT
>>XP_016856151 (OMIM: 601502) PREDICTED: high affinity i (195 aa)
initn: 1266 init1: 618 opt: 640 Z-score: 641.0 bits: 126.3 E(85289): 5.7e-29
Smith-Waterman score: 975; 61.8% identity (63.9% similar) in 280 aa overlap (95-374:12-195)
70 80 90 100 110 120
pF1KB6 TSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPLALRC
:.. .. :::::::::::: :::::::::
XP_016 MWFLTTLLLWVPVDGQV--GWLLLQVSSRVFMEGEPLALRC
10 20 30
130 140 150 160 170 180
pF1KB6 HAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGISVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGIS--
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB6 VKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRNTSSE
XP_016 ------------------------------------------------------------
250 260 270 280 290 300
pF1KB6 YQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVGIMFL
. : :::::::::::::::::::::::
XP_016 --------------------------------QYTVKGLQLPTPVWFHVLFYLAVGIMFL
100 110 120
310 320 330 340 350 360
pF1KB6 VNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQLQEG
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 VNTVLWVTIRKELKRKKKWNLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQLQEG
130 140 150 160 170 180
370
pF1KB6 VHRKEPQGAT
::::::::::
XP_016 VHRKEPQGAT
190
374 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:27:53 2016 done: Sat Nov 5 11:27:55 2016
Total Scan time: 7.850 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]