FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6563, 374 aa 1>>>pF1KB6563 374 - 374 aa - 374 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2880+/-0.000367; mu= 16.4680+/- 0.023 mean_var=66.3177+/-13.284, 0's: 0 Z-trim(112.9): 89 B-trim: 593 in 1/57 Lambda= 0.157492 statistics sampled from 21848 (21947) to 21848 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.257), width: 16 Scan time: 6.640 The best scores are: opt bits E(85289) NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 2502 577.5 1.7e-164 NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 1229 288.3 1.9e-77 NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 1218 285.8 1.1e-76 NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 1188 278.9 1.2e-74 XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 1040 245.3 1.4e-64 XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 990 233.9 3.7e-61 NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 883 209.6 8.8e-54 NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 877 208.3 2.3e-53 NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 874 207.6 3.6e-53 NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 873 207.4 4.3e-53 NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 871 206.9 5.8e-53 NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 871 206.9 5.8e-53 NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 869 206.5 8e-53 XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 864 205.3 1.8e-52 NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 864 205.3 1.8e-52 XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 853 202.8 8.6e-52 NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 847 201.5 2.7e-51 NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 843 200.6 4.8e-51 NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 834 198.6 2.4e-50 NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 826 196.7 7e-50 NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 821 195.6 1.6e-49 NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 818 194.9 2.6e-49 NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 818 194.9 2.6e-49 NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 816 194.4 3.6e-49 NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 810 193.0 7.9e-49 NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 810 193.0 8.4e-49 NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 810 193.0 8.4e-49 NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 804 191.7 2.4e-48 XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 796 190.1 1.9e-47 XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 791 189.0 4.2e-47 XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 775 185.0 1.5e-46 XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 760 181.7 2.2e-45 NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 746 178.5 1.8e-44 NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 743 177.8 2.9e-44 XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 718 172.1 1.5e-42 XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 692 166.2 9.4e-41 XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 692 166.2 9.4e-41 XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 692 166.2 9.4e-41 XP_016883305 (OMIM: 102200,103580,139320,166350,17 ( 320) 662 159.4 1.1e-38 XP_016883309 (OMIM: 102200,103580,139320,166350,17 ( 320) 662 159.4 1.1e-38 NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335) 660 159.0 1.5e-38 NP_001296769 (OMIM: 102200,103580,139320,166350,17 ( 335) 660 159.0 1.5e-38 NP_000507 (OMIM: 102200,103580,139320,166350,17480 ( 394) 660 159.0 1.7e-38 NP_001070956 (OMIM: 102200,103580,139320,166350,17 ( 395) 660 159.0 1.7e-38 XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 657 158.3 2.2e-38 NP_536350 (OMIM: 102200,103580,139320,166350,17480 (1037) 660 159.2 3.9e-38 XP_016883301 (OMIM: 102200,103580,139320,166350,17 (1038) 660 159.2 3.9e-38 NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 650 156.6 6.1e-38 NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282) 625 151.0 3.2e-36 XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284) 612 148.0 2.5e-35 >>NP_002059 (OMIM: 139314) guanine nucleotide-binding pr (374 aa) initn: 2502 init1: 2502 opt: 2502 Z-score: 3074.3 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2502; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR 310 320 330 340 350 360 370 pF1KB6 DSVLARYLDEINLL :::::::::::::: NP_002 DSVLARYLDEINLL 370 >>NP_002063 (OMIM: 163000,185300,600998) guanine nucleot (359 aa) initn: 1345 init1: 1229 opt: 1229 Z-score: 1511.3 bits: 288.3 E(85289): 1.9e-77 Smith-Waterman score: 1336; 55.8% identity (80.9% similar) in 362 aa overlap (13-374:10-359) 10 20 30 40 50 60 pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK ::.:. : : :...::.: : ..:.. : :::::::: :::::::::: NP_002 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIK 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD :::::::.:::.:...:: :::::::..:.:::.::. :.::.. ..: ::.:: : NP_002 QMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ ::..::. :. :.. :: : ::. ::.::::..: ::. :::. :.:... .:.:: : NP_002 VEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ :::: :.::::: :: :..:.. .:.::::::.:::.::::::::: ....:..:::::: NP_002 DVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG : :...::::.:: ::: ::. :::...:::::::: :.::::: :::. ::: ..: NP_002 VLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR :..::.::..::: :.. . .:...: ..::.::::::.::: :: :. NP_002 PQRDAQAAREFILKMFVDL------NPDSDKI------IYSHFTCATDTENIRFVFAAVK 300 310 320 330 340 370 pF1KB6 DSVLARYLDEINLL :..: : : ::. NP_002 DTILQLNLKEYNLV 350 >>NP_002058 (OMIM: 139313) guanine nucleotide-binding pr (359 aa) initn: 1334 init1: 1218 opt: 1218 Z-score: 1497.8 bits: 285.8 E(85289): 1.1e-76 Smith-Waterman score: 1325; 55.8% identity (80.4% similar) in 362 aa overlap (13-374:10-359) 10 20 30 40 50 60 pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK ::... : . :.. ::.. : ..:.. : :::::::: :::::::::: NP_002 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIK 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD :::::::::::::...:: :::::::..:.:::.::: :.: .. ..: .: :. : NP_002 QMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ ::::::..:..:.. ::.: ::. ::.::::..: ::: :::. ..::. ::.:: : NP_002 VEKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ :::: :.::::: :: :.... .:.::::::.:::.::::::::: ....:..:::::: NP_002 DVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG : :...::::.:: ::: ::. :::...:::::::: :.::.:: :::. ::: :.: NP_002 VLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR :..::.::..::: :.. . .:...: ..::.::::::.::: :: :. NP_002 PQRDAQAAREFILKMFVDL------NPDSDKI------IYSHFTCATDTENIRFVFAAVK 300 310 320 330 340 370 pF1KB6 DSVLARYLDEINLL :..: : : ::. NP_002 DTILQLNLKEYNLV 350 >>NP_004288 (OMIM: 604397) guanine nucleotide-binding pr (355 aa) initn: 1290 init1: 1176 opt: 1188 Z-score: 1461.1 bits: 278.9 E(85289): 1.2e-74 Smith-Waterman score: 1289; 54.1% identity (77.9% similar) in 366 aa overlap (9-374:4-355) 10 20 30 40 50 60 pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK :: ::. .:: . :.. ::.: : ..::. : :::::::: :::::::::: NP_004 MAGCC--CLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIK 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD :::::::.:::.:.:::: :::::::..:.:::.::. :.: . ..:..:... . NP_004 QMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ ::. . .. . :.. ::.: ::. ::.::::..: ::: :::. ..::. ..::: : NP_004 VDKVSMLSREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ :::: :.::::: :: :.... .:.::::::.:::.:::::::.: ..:.:..:::::: NP_004 DVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG : : ..::::.:: ::: ::. ::: ..:::::::: :.::::: ::: .::: . : NP_004 VLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR ::::..::. ::: .: . .:. . . ..::.::::::.::: :: :. NP_004 PKQDVRAARDFILKLYQDQ------NPD------KEKVIYSHFTCATDTDNIRFVFAAVK 300 310 320 330 340 370 pF1KB6 DSVLARYLDEINLL :..: : :.::. NP_004 DTILQLNLREFNLV 350 >>XP_016870117 (OMIM: 163000,185300,600998) PREDICTED: g (301 aa) initn: 1156 init1: 1040 opt: 1040 Z-score: 1280.4 bits: 245.3 E(85289): 1.4e-64 Smith-Waterman score: 1147; 54.6% identity (80.5% similar) in 313 aa overlap (62-374:1-301) 40 50 60 70 80 90 pF1KB6 LLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMR ::::::.:::.:...:: :::::::..:. XP_016 MRIIHGSGYSDEDKRGFTKLVYQNIFTAMQ 10 20 30 100 110 120 130 140 150 pF1KB6 AMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERR :::.::. :.::.. ..: ::.:: : ::..::. :. :.. :: : ::. ::.:: XP_016 AMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRR 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 REFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGG ::..: ::. :::. :.:... .:.:: ::::: :.::::: :: :..:.. .:.::::: XP_016 REYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 QKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTS :.:::.::::::::: ....:..:::::: : :...::::.:: ::: ::. :::...: XP_016 QRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 VILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSK ::::::: :.::::: :::. ::: ..::..::.::..::: :.. . .:...: XP_016 VILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDL------NPDSDK 220 230 240 250 260 340 350 360 370 pF1KB6 KGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL ..::.::::::.::: :: :.:..: : : ::. XP_016 I------IYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV 270 280 290 300 >>XP_016870830 (OMIM: 604397) PREDICTED: guanine nucleot (301 aa) initn: 1124 init1: 990 opt: 990 Z-score: 1219.0 bits: 233.9 E(85289): 3.7e-61 Smith-Waterman score: 1091; 52.7% identity (77.6% similar) in 313 aa overlap (62-374:1-301) 40 50 60 70 80 90 pF1KB6 LLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMR ::::::.:::.:.:::: :::::::..:. XP_016 MRIIHGSGYSDEDRKGFTKLVYQNIFTAMQ 10 20 30 100 110 120 130 140 150 pF1KB6 AMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERR :::.::. :.: . ..:..:... . ::. . .. . :.. ::.: ::. ::.:: XP_016 AMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLSREQVEAIKQLWQDPGIQECYDRR 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 REFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGG ::..: ::: :::. ..::. ..::: ::::: :.::::: :: :.... .:.::::: XP_016 REYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 QKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTS :.:::.:::::::.: ..:.:..:::::: : : ..::::.:: ::: ::. ::: ..: XP_016 QRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 VILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSK ::::::: :.::::: ::: .::: . :::::..::. ::: .: ..:. XP_016 VILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFILKLYQD------QNPD--- 220 230 240 250 260 340 350 360 370 pF1KB6 KGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL . . ..::.::::::.::: :: :.:..: : :.::. XP_016 ---KEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNLV 270 280 290 300 >>NP_002060 (OMIM: 139310) guanine nucleotide-binding pr (354 aa) initn: 954 init1: 629 opt: 883 Z-score: 1086.5 bits: 209.6 E(85289): 8.8e-54 Smith-Waterman score: 962; 43.7% identity (69.8% similar) in 364 aa overlap (13-374:3-354) 10 20 30 40 50 pF1KB6 MARSLTWRCCPWC-LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFI : :. ..:::.. .. :.: : :. .. :.:::::: :::::::.. NP_002 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIV 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHA-SLVMS :::.::: ::::::: : .. .::.: . :. :.:.:: ::.: :. : .: . NP_002 KQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 QDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPT . . . :.... ::.:.:..::..: ::..: :::.:::. :.::.. .:.:: NP_002 AGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 AQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEY :::::.:. :::: : :. . .... :::::.:::::::::::.: :.:. ..::.: NP_002 QQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 DQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSF : : :... :::.::. :: .: . :: .::.:::::: :..:::: : :. .: . NP_002 DLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 QGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKD : . ::: : : : .: ......:.::::::.:.. :: NP_002 AGSNTYEEAAA----------YIQC--QFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDA 300 310 320 330 360 370 pF1KB6 VRDSVLARYLDEINLL : : .. : . .:. NP_002 VTDVIIKNNLKDCGLF 340 350 >>NP_002061 (OMIM: 139360,192605) guanine nucleotide-bin (355 aa) initn: 946 init1: 618 opt: 877 Z-score: 1079.2 bits: 208.3 E(85289): 2.3e-53 Smith-Waterman score: 954; 43.0% identity (69.3% similar) in 365 aa overlap (13-374:3-355) 10 20 30 40 50 pF1KB6 MARSLTWRCCPWC-LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFI : .. ..::::. .. :.. : :. .. :.:::::: :::::::.. NP_002 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIV 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHAS--LVM :::.::: :::::: . .: .::.: . :. :...:: ::: :. : : ... NP_002 KQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFAL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 SQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVP : . .. ..... :: : :..::. : ::..: :::.:::. ::::.. :.: NP_002 SCTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 TAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSE : :::::.:. :::: : :. . .... :::::.:::::::::::.: :.:. ..:: NP_002 TQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 YDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPS :: : :... :::.::. :: .: . :: .::.:::::: :..:::: : :. :: NP_002 YDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 FQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFK . : .. :::. .: . . : .: ......:.::::::.:.. :: NP_002 YTGANKYDEAAS-YIQSKF-----------EDLNKRKDTKEIYTHFTCATDTKNVQFVFD 300 310 320 330 360 370 pF1KB6 DVRDSVLARYLDEINLL : : .. : . .:. NP_002 AVTDVIIKNNLKDCGLF 340 350 >>NP_006487 (OMIM: 139370,602483) guanine nucleotide-bin (354 aa) initn: 943 init1: 627 opt: 874 Z-score: 1075.5 bits: 207.6 E(85289): 3.6e-53 Smith-Waterman score: 953; 43.8% identity (69.3% similar) in 365 aa overlap (13-373:3-353) 10 20 30 40 50 pF1KB6 MARSLTWRCCPWC-LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFI : :. ..:::.. .. :.: : :. .. :.:::::: :::::::.. NP_006 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIV 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPF---SRPESKHHASLV :::.::: ::::.: : .. .::.: . :. :.:.:: ::.: : .: .. .. .. NP_006 KQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 MSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYV .. : : : :.... ::::.:..::. : ::..: ::: :::. :.::.. .:. NP_006 AGSAEEGVMTPE--LAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYI 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 PTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLS :: :::::.:. :::: : :. . ... :::::.:::::::::::.: :.:. ..:: NP_006 PTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 EYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFP .:: : :... :::.::. :: .: . :: ::.:::::: :..:::: : :. .: NP_006 DYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYP 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB6 SFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVF . : . ::: : : : .. ......:.::::::.:.. :: NP_006 EYTGSNTYEEAAA----------YIQC--QFEDLNRRKDTKEIYTHFTCATDTKNVQFVF 290 300 310 320 330 360 370 pF1KB6 KDVRDSVLARYLDEINLL : : .. : : .: NP_006 DAVTDVIIKNNLKECGLY 340 350 >>NP_001095856 (OMIM: 139395) guanine nucleotide-binding (354 aa) initn: 932 init1: 632 opt: 873 Z-score: 1074.3 bits: 207.4 E(85289): 4.3e-53 Smith-Waterman score: 953; 43.1% identity (70.2% similar) in 362 aa overlap (14-374:5-354) 10 20 30 40 50 60 pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK .. . : .:. ..:... : :. ..: .:::::: :::::::..: NP_001 MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVK 10 20 30 40 50 70 80 90 100 110 pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPES-KHHASLVMSQ ::.::: ::::.: :. ..:.: . :. :...:: : : . :.: . . .: NP_001 QMKIIHKNGYSEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 DPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTA . . . . : ... :::: ::.::.:: :..: :::.:::. :.::: ::::. NP_001 NTLEDGGMTPQLAEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 QDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYD ::::.::. :::: : :: . ..:. :::::.:::::::::::.: .:. :.:: :: NP_001 QDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 QCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQ . : :... :::.::: ::..: . .:..::..::::: ::..::. ::. :: . NP_001 MVLVEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYT 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 GPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDV ::. : : .: ... . . :: ......::.::::::::.. :: : NP_001 GPNT-FEDAGNYIKNQFLDL---------NLKK--EDKEIYSHMTCATDTQNVKFVFDAV 300 310 320 330 360 370 pF1KB6 RDSVLARYLDEINLL : .. . : . .:. NP_001 TDIIIKENLKDCGLF 340 350 374 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:20:00 2016 done: Fri Nov 4 23:20:01 2016 Total Scan time: 6.640 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]