FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6565, 374 aa 1>>>pF1KB6565 374 - 374 aa - 374 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5274+/-0.000386; mu= 15.7167+/- 0.024 mean_var=87.3202+/-18.620, 0's: 0 Z-trim(114.4): 170 B-trim: 1326 in 2/51 Lambda= 0.137251 statistics sampled from 23981 (24225) to 23981 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.284), width: 16 Scan time: 7.570 The best scores are: opt bits E(85289) NP_006860 (OMIM: 608114) arf-GAP with dual PH doma ( 374) 2611 527.2 2.4e-149 NP_001271237 (OMIM: 608114) arf-GAP with dual PH d ( 385) 2426 490.5 2.7e-138 NP_001271239 (OMIM: 608114) arf-GAP with dual PH d ( 302) 2107 427.3 2.3e-119 NP_001271238 (OMIM: 608114) arf-GAP with dual PH d ( 302) 2107 427.3 2.3e-119 NP_001271240 (OMIM: 608114) arf-GAP with dual PH d ( 279) 1896 385.5 8.1e-107 NP_060874 (OMIM: 608635) arf-GAP with dual PH doma ( 381) 1570 321.0 2.8e-87 XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP wit ( 462) 340 77.5 6.7e-14 XP_016867222 (OMIM: 616813) PREDICTED: arf-GAP wit ( 527) 340 77.6 7.4e-14 XP_005250000 (OMIM: 616813) PREDICTED: arf-GAP wit ( 565) 340 77.6 7.8e-14 XP_016867223 (OMIM: 616813) PREDICTED: arf-GAP wit ( 580) 340 77.6 7.9e-14 NP_001268229 (OMIM: 616813) arf-GAP with GTPase, A ( 580) 340 77.6 7.9e-14 XP_016867221 (OMIM: 616813) PREDICTED: arf-GAP wit ( 630) 340 77.7 8.5e-14 XP_011514082 (OMIM: 616813) PREDICTED: arf-GAP wit ( 683) 340 77.7 9e-14 NP_114152 (OMIM: 616813) arf-GAP with GTPase, ANK ( 911) 340 77.8 1.1e-13 NP_073570 (OMIM: 616916) stromal membrane-associat ( 429) 331 75.7 2.2e-13 NP_055531 (OMIM: 607763) arf-GAP with coiled-coil, ( 740) 334 76.5 2.2e-13 XP_005248817 (OMIM: 611372) PREDICTED: stromal mem ( 250) 326 74.6 2.9e-13 XP_011534349 (OMIM: 611372) PREDICTED: stromal mem ( 429) 326 74.7 4.3e-13 NP_001268368 (OMIM: 611372) stromal membrane-assoc ( 436) 326 74.8 4.4e-13 NP_068759 (OMIM: 611372) stromal membrane-associat ( 440) 326 74.8 4.4e-13 XP_011534347 (OMIM: 611372) PREDICTED: stromal mem ( 456) 326 74.8 4.5e-13 NP_001037770 (OMIM: 611372) stromal membrane-assoc ( 467) 326 74.8 4.6e-13 NP_055585 (OMIM: 605476) arf-GAP with GTPase, ANK ( 836) 326 75.0 7.2e-13 XP_005268683 (OMIM: 605476) PREDICTED: arf-GAP wit ( 856) 326 75.0 7.3e-13 XP_005268682 (OMIM: 605476) PREDICTED: arf-GAP wit (1172) 326 75.1 9.3e-13 NP_001116244 (OMIM: 605476) arf-GAP with GTPase, A (1192) 326 75.1 9.4e-13 XP_016874261 (OMIM: 605476) PREDICTED: arf-GAP wit (1192) 326 75.1 9.4e-13 XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 313 72.4 4e-12 XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 313 72.4 4e-12 XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 313 72.4 4e-12 NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778) 313 72.4 4e-12 XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP wit ( 785) 313 72.4 4.1e-12 XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP wit ( 806) 313 72.4 4.2e-12 XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 313 72.4 4.2e-12 XP_016861537 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 313 72.4 4.2e-12 XP_011510904 (OMIM: 607766) PREDICTED: arf-GAP wit ( 820) 313 72.4 4.2e-12 XP_016861536 (OMIM: 607766) PREDICTED: arf-GAP wit ( 841) 313 72.4 4.3e-12 XP_016861535 (OMIM: 607766) PREDICTED: arf-GAP wit ( 848) 313 72.4 4.3e-12 NP_055729 (OMIM: 608651) arf-GAP with GTPase, ANK ( 804) 304 70.6 1.4e-11 XP_005246116 (OMIM: 608651) PREDICTED: arf-GAP wit ( 808) 304 70.6 1.4e-11 NP_001032208 (OMIM: 608651) arf-GAP with GTPase, A ( 857) 304 70.6 1.5e-11 XP_006712298 (OMIM: 608651) PREDICTED: arf-GAP wit ( 882) 304 70.6 1.5e-11 XP_006712297 (OMIM: 608651) PREDICTED: arf-GAP wit ( 886) 304 70.6 1.5e-11 XP_011508851 (OMIM: 608651) PREDICTED: arf-GAP wit (1073) 304 70.7 1.8e-11 XP_011508850 (OMIM: 608651) PREDICTED: arf-GAP wit (1098) 304 70.7 1.8e-11 XP_016858771 (OMIM: 608651) PREDICTED: arf-GAP wit (1106) 304 70.7 1.8e-11 XP_011508849 (OMIM: 608651) PREDICTED: arf-GAP wit (1126) 304 70.7 1.8e-11 XP_006712300 (OMIM: 608651) PREDICTED: arf-GAP wit (1147) 304 70.7 1.9e-11 XP_006712302 (OMIM: 608651) PREDICTED: arf-GAP wit (1151) 304 70.7 1.9e-11 XP_016868958 (OMIM: 605953) PREDICTED: arf-GAP wit (1072) 291 68.1 1.1e-10 >>NP_006860 (OMIM: 608114) arf-GAP with dual PH domain-c (374 aa) initn: 2611 init1: 2611 opt: 2611 Z-score: 2802.1 bits: 527.2 E(85289): 2.4e-149 Smith-Waterman score: 2611; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB6 MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPML 310 320 330 340 350 360 370 pF1KB6 PQEYAVEAHFKHKP :::::::::::::: NP_006 PQEYAVEAHFKHKP 370 >>NP_001271237 (OMIM: 608114) arf-GAP with dual PH domai (385 aa) initn: 2422 init1: 2422 opt: 2426 Z-score: 2604.0 bits: 490.5 E(85289): 2.7e-138 Smith-Waterman score: 2426; 97.8% identity (98.0% similar) in 358 aa overlap (21-374:28-385) 10 20 30 40 pF1KB6 MAKERRRAVLELLQRPGNARCADCGAP----DPDWASYTLGVFICLSCSGIHR ::. : :::::::::::::::::::::: NP_001 MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 NIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWI 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 RAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAK 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 EPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAAR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 FHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB6 DAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVA 310 320 330 340 350 360 350 360 370 pF1KB6 AFQKAVDRPMLPQEYAVEAHFKHKP ::::::::::::::::::::::::: NP_001 AFQKAVDRPMLPQEYAVEAHFKHKP 370 380 >>NP_001271239 (OMIM: 608114) arf-GAP with dual PH domai (302 aa) initn: 2107 init1: 2107 opt: 2107 Z-score: 2264.0 bits: 427.3 E(85289): 2.3e-119 Smith-Waterman score: 2107; 100.0% identity (100.0% similar) in 302 aa overlap (73-374:1-302) 50 60 70 80 90 100 pF1KB6 SCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQ :::::::::::::::::::::::::::::: NP_001 MASHGNDAARARFESKVPSFYYRPTPSDCQ 10 20 30 110 120 130 140 150 160 pF1KB6 LLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKY 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 FNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWF 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 NALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 MYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETES 220 230 240 250 260 270 350 360 370 pF1KB6 DQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP :::::::::::::::::::::::::::::::: NP_001 DQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP 280 290 300 >>NP_001271238 (OMIM: 608114) arf-GAP with dual PH domai (302 aa) initn: 2107 init1: 2107 opt: 2107 Z-score: 2264.0 bits: 427.3 E(85289): 2.3e-119 Smith-Waterman score: 2107; 100.0% identity (100.0% similar) in 302 aa overlap (73-374:1-302) 50 60 70 80 90 100 pF1KB6 SCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQ :::::::::::::::::::::::::::::: NP_001 MASHGNDAARARFESKVPSFYYRPTPSDCQ 10 20 30 110 120 130 140 150 160 pF1KB6 LLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKY 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 FNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWF 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 NALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 MYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETES 220 230 240 250 260 270 350 360 370 pF1KB6 DQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP :::::::::::::::::::::::::::::::: NP_001 DQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP 280 290 300 >>NP_001271240 (OMIM: 608114) arf-GAP with dual PH domai (279 aa) initn: 1896 init1: 1896 opt: 1896 Z-score: 2038.7 bits: 385.5 E(85289): 8.1e-107 Smith-Waterman score: 1896; 99.6% identity (100.0% similar) in 273 aa overlap (102-374:7-279) 80 90 100 110 120 130 pF1KB6 FMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGY .::::::::::::::::::::::::::::: NP_001 MVLASLELLREQWIRAKYERQEFIYPEKQEPYSAGY 10 20 30 140 150 160 170 180 190 pF1KB6 REGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGH 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 PHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 NYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHG 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB6 FPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFK 220 230 240 250 260 270 pF1KB6 HKP ::: NP_001 HKP >>NP_060874 (OMIM: 608635) arf-GAP with dual PH domain-c (381 aa) initn: 1544 init1: 740 opt: 1570 Z-score: 1688.0 bits: 321.0 E(85289): 2.8e-87 Smith-Waterman score: 1570; 58.8% identity (84.1% similar) in 364 aa overlap (3-361:4-366) 10 20 30 40 50 pF1KB6 MAKER-RRAVLELLQRP--GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSK .:: .. .::::. : :::.:::::: ::::::: ::.::::.: :.:::.:..:. NP_060 MGDRERNKKRLLELLRAPDTGNAHCADCGAADPDWASYKLGIFICLNCCGVHRNFPDISR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 VKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQ ::::::: :... :::: .:: ..:.::..::.::: : .:: .:.::::::::::. NP_060 VKSVRLDFWDDSIVEFMIHNGNLRVKAKFEARVPAFYYIPQANDCLVLKEQWIRAKYERR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 EFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMK ::. . . : ::::::::::::.::: ::::: ::: ::::.....: ::::.. NP_060 EFM-ADGETISLPGNREGFLWKRGRDNSQFLRRKFVLLAREGLLKYFTKEQGKSPKAVIS 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 IEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVA :. :::::: :::::::::.:: .:. :::.:.:::.:::::::::::::::..::..: NP_060 IKDLNATFQTEKIGHPHGLQITYRRDGHTRNLFVYHESGKEIVDWFNALRAARLQYLKMA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 FPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMD--DRRLMYFKDPLDAFAR :: ...::: :.:::::.:.:::::::: : :.::::..: .:::.:.:.::::: . NP_060 FPELPESELVPFLTRNYLKQGFMEKTGPKQKEPFKKRWFALDCHERRLLYYKNPLDAFEQ 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 GEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKA :.::.:.::.:: . . .: . .:..: :.:::::.:.:...: .:..:.::. ... . NP_060 GQVFLGNKEQGYEAYEDLPKGIRGNRWKAGLTIVTPERRFVLTCPSEKEQQEWLESLRGV 300 310 320 330 340 350 360 370 pF1KB6 VDRPMLPQEYAVEAHFKHKP .. :. : NP_060 LSSPLTPLNRLTASTESGRSSR 360 370 380 >>XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP with GT (462 aa) initn: 236 init1: 236 opt: 340 Z-score: 370.6 bits: 77.5 E(85289): 6.7e-14 Smith-Waterman score: 340; 43.4% identity (71.7% similar) in 106 aa overlap (17-121:224-328) 10 20 30 40 pF1KB6 MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSG ::. : :: ::.::::: .::...:. ::: XP_016 SLQGCRSAKDKTRLGNQNAALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSG 200 210 220 230 240 250 50 60 70 80 90 100 pF1KB6 IHRNI-PQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLR :::.. ..:.:.:. :: : . :.. :: : . .:. . . : .: :. :. . XP_016 IHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGALGG-YSKPGPDACREEK 260 270 280 290 300 310 110 120 130 140 150 160 pF1KB6 EQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNR :.:::::::.. :. : XP_016 ERWIRAKYEQKLFLAPLPSSDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGD 320 330 340 350 360 370 >>XP_016867222 (OMIM: 616813) PREDICTED: arf-GAP with GT (527 aa) initn: 236 init1: 236 opt: 340 Z-score: 369.8 bits: 77.6 E(85289): 7.4e-14 Smith-Waterman score: 340; 43.4% identity (71.7% similar) in 106 aa overlap (17-121:289-393) 10 20 30 40 pF1KB6 MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSG ::. : :: ::.::::: .::...:. ::: XP_016 SLQGCRSAKDKTRLGNQNAALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSG 260 270 280 290 300 310 50 60 70 80 90 100 pF1KB6 IHRNI-PQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLR :::.. ..:.:.:. :: : . :.. :: : . .:. . . : .: :. :. . XP_016 IHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGALGG-YSKPGPDACREEK 320 330 340 350 360 370 110 120 130 140 150 160 pF1KB6 EQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNR :.:::::::.. :. : XP_016 ERWIRAKYEQKLFLAPLPSSDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGD 380 390 400 410 420 430 >>XP_005250000 (OMIM: 616813) PREDICTED: arf-GAP with GT (565 aa) initn: 236 init1: 236 opt: 340 Z-score: 369.4 bits: 77.6 E(85289): 7.8e-14 Smith-Waterman score: 340; 43.4% identity (71.7% similar) in 106 aa overlap (17-121:327-431) 10 20 30 40 pF1KB6 MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSG ::. : :: ::.::::: .::...:. ::: XP_005 SLQGCRSAKDKTRLGNQNAALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSG 300 310 320 330 340 350 50 60 70 80 90 100 pF1KB6 IHRNI-PQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLR :::.. ..:.:.:. :: : . :.. :: : . .:. . . : .: :. :. . XP_005 IHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGALGG-YSKPGPDACREEK 360 370 380 390 400 410 110 120 130 140 150 160 pF1KB6 EQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNR :.:::::::.. :. : XP_005 ERWIRAKYEQKLFLAPLPSSDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGD 420 430 440 450 460 470 >>XP_016867223 (OMIM: 616813) PREDICTED: arf-GAP with GT (580 aa) initn: 236 init1: 236 opt: 340 Z-score: 369.2 bits: 77.6 E(85289): 7.9e-14 Smith-Waterman score: 340; 43.4% identity (71.7% similar) in 106 aa overlap (17-121:342-446) 10 20 30 40 pF1KB6 MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSG ::. : :: ::.::::: .::...:. ::: XP_016 SLQGCRSAKDKTRLGNQNAALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSG 320 330 340 350 360 370 50 60 70 80 90 100 pF1KB6 IHRNI-PQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLR :::.. ..:.:.:. :: : . :.. :: : . .:. . . : .: :. :. . XP_016 IHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGALGG-YSKPGPDACREEK 380 390 400 410 420 430 110 120 130 140 150 160 pF1KB6 EQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNR :.:::::::.. :. : XP_016 ERWIRAKYEQKLFLAPLPSSDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGD 440 450 460 470 480 490 374 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:42:25 2016 done: Sat Nov 5 20:42:26 2016 Total Scan time: 7.570 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]