Result of FASTA (omim) for
pF1KB6567
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6567, 374 aa
1>>>pF1KB6567 374 - 374 aa - 374 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4158+/-0.000435; mu= 15.9119+/- 0.027
mean_var=65.8467+/-13.772, 0's: 0 Z-trim(108.9): 134 B-trim: 765 in 1/53
Lambda= 0.158055
statistics sampled from 16869 (17006) to 16869 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.558), E-opt: 0.2 (0.199), width: 16
Scan time: 7.080
The best scores are: opt bits E(85289)
NP_002631 (OMIM: 601697,617115) serpin B8 isoform ( 374) 2476 573.9 2.1e-163
NP_942130 (OMIM: 601697,617115) serpin B8 isoform ( 374) 2476 573.9 2.1e-163
XP_011512976 (OMIM: 173321,613453) PREDICTED: serp ( 376) 1658 387.4 2.9e-107
NP_001258754 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1658 387.4 2.9e-107
XP_011512975 (OMIM: 173321,613453) PREDICTED: serp ( 376) 1658 387.4 2.9e-107
NP_004559 (OMIM: 173321,613453) serpin B6 isoform ( 376) 1658 387.4 2.9e-107
NP_001258753 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1658 387.4 2.9e-107
NP_001284628 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1658 387.4 2.9e-107
NP_001284629 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1658 387.4 2.9e-107
NP_001182220 (OMIM: 173321,613453) serpin B6 isofo ( 380) 1658 387.4 3e-107
XP_016866429 (OMIM: 173321,613453) PREDICTED: serp ( 380) 1658 387.4 3e-107
NP_001258751 (OMIM: 173321,613453) serpin B6 isofo ( 390) 1658 387.4 3e-107
NP_001258752 (OMIM: 173321,613453) serpin B6 isofo ( 395) 1658 387.4 3.1e-107
XP_011512974 (OMIM: 173321,613453) PREDICTED: serp ( 454) 1658 387.4 3.4e-107
XP_006722547 (OMIM: 601697,617115) PREDICTED: serp ( 247) 1581 369.7 4e-102
XP_016881280 (OMIM: 601697,617115) PREDICTED: serp ( 247) 1581 369.7 4e-102
NP_001027018 (OMIM: 601697,617115) serpin B8 isofo ( 242) 1579 369.3 5.3e-102
XP_016881279 (OMIM: 601697,617115) PREDICTED: serp ( 259) 1576 368.6 9.1e-102
XP_011524327 (OMIM: 601697,617115) PREDICTED: serp ( 259) 1576 368.6 9.1e-102
XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 i ( 376) 1561 365.3 1.3e-100
NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] ( 376) 1561 365.3 1.3e-100
XP_011512978 (OMIM: 173321,613453) PREDICTED: serp ( 332) 1404 329.4 7.2e-90
XP_016866430 (OMIM: 173321,613453) PREDICTED: serp ( 332) 1404 329.4 7.2e-90
XP_011512980 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 1340 314.8 1.7e-85
XP_016866431 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 1340 314.8 1.7e-85
XP_016866432 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 1340 314.8 1.7e-85
NP_001263419 (OMIM: 601697,617115) serpin B8 isofo ( 192) 1267 298.1 1.1e-80
NP_109591 (OMIM: 130135) leukocyte elastase inhibi ( 379) 1230 289.8 7.1e-78
XP_011512636 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 1230 289.8 7.1e-78
XP_011512635 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 1230 289.8 7.1e-78
XP_016881281 (OMIM: 601697,617115) PREDICTED: serp ( 194) 1224 288.3 1e-77
XP_011512637 (OMIM: 130135) PREDICTED: leukocyte e ( 330) 1045 247.6 3.1e-65
NP_001137290 (OMIM: 173390) plasminogen activator ( 415) 994 236.0 1.2e-61
NP_002566 (OMIM: 173390) plasminogen activator inh ( 415) 994 236.0 1.2e-61
NP_002965 (OMIM: 600518) serpin B4 isoform 1 [Homo ( 390) 928 220.9 3.9e-57
XP_011524440 (OMIM: 600518) PREDICTED: serpin B4 i ( 390) 928 220.9 3.9e-57
NP_008850 (OMIM: 600517) serpin B3 [Homo sapiens] ( 390) 924 220.0 7.3e-57
XP_011524553 (OMIM: 615682) PREDICTED: serpin B11 ( 392) 911 217.0 5.7e-56
NP_536723 (OMIM: 615682) serpin B11 isoform a [Hom ( 392) 911 217.0 5.7e-56
XP_011524329 (OMIM: 602058) PREDICTED: serpin B10 ( 397) 904 215.5 1.8e-55
NP_005015 (OMIM: 602058) serpin B10 [Homo sapiens] ( 397) 904 215.5 1.8e-55
NP_002630 (OMIM: 154790) serpin B5 [Homo sapiens] ( 375) 871 207.9 3.1e-53
XP_011524551 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 866 206.8 7.5e-53
XP_016881556 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 866 206.8 7.5e-53
XP_011524550 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 866 206.8 7.5e-53
NP_001294857 (OMIM: 615662) serpin B12 isoform 1 [ ( 425) 866 206.8 7.5e-53
XP_011524548 (OMIM: 615662) PREDICTED: serpin B12 ( 432) 866 206.8 7.7e-53
XP_005266835 (OMIM: 615662) PREDICTED: serpin B12 ( 437) 866 206.8 7.7e-53
NP_536722 (OMIM: 615662) serpin B12 isoform 2 [Hom ( 405) 857 204.7 3e-52
XP_011524331 (OMIM: 604445) PREDICTED: serpin B13 ( 390) 856 204.5 3.4e-52
>>NP_002631 (OMIM: 601697,617115) serpin B8 isoform a [H (374 aa)
initn: 2476 init1: 2476 opt: 2476 Z-score: 3054.7 bits: 573.9 E(85289): 2.1e-163
Smith-Waterman score: 2476; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH
310 320 330 340 350 360
370
pF1KB6 KTNCILFCGRFSSP
::::::::::::::
NP_002 KTNCILFCGRFSSP
370
>>NP_942130 (OMIM: 601697,617115) serpin B8 isoform a [H (374 aa)
initn: 2476 init1: 2476 opt: 2476 Z-score: 3054.7 bits: 573.9 E(85289): 2.1e-163
Smith-Waterman score: 2476; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH
310 320 330 340 350 360
370
pF1KB6 KTNCILFCGRFSSP
::::::::::::::
NP_942 KTNCILFCGRFSSP
370
>>XP_011512976 (OMIM: 173321,613453) PREDICTED: serpin B (376 aa)
initn: 1100 init1: 833 opt: 1658 Z-score: 2046.6 bits: 387.4 E(85289): 2.9e-107
Smith-Waterman score: 1658; 66.9% identity (84.7% similar) in 378 aa overlap (1-374:1-376)
10 20 30 40 50 60
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
:: : :::::::..:.: ::. :::.::::::::.: :::::.:::::.:::::.: : .
XP_011 MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF
10 20 30 40 50
70 80 90 100 110
pF1KB6 YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE
:.: :::.::::::.:::.:::::::: ::::::::.:::: .:.. ::::::::.:
XP_011 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR
::.: .:. ::::: ::::::::::.:.:. :.:::::.::::::.::.:.:.::::.
XP_011 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT
. :. :::... :.: ::::::.. :: : :. ::.: :::: .::.:.:.:::..:
XP_011 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK
:: .::: :::::: :: . . . .:.: :::.:::::::.: :: ::: :::. .:
XP_011 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF
::::::: . .. ::::.:: ::::::::::::::::.. ::.:. ::::::::::::
XP_011 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF
300 310 320 330 340 350
360 370
pF1KB6 IRHHKTNCILFCGRFSSP
:.: ::: ::::::::::
XP_011 IQHSKTNGILFCGRFSSP
360 370
>>NP_001258754 (OMIM: 173321,613453) serpin B6 isoform a (376 aa)
initn: 1100 init1: 833 opt: 1658 Z-score: 2046.6 bits: 387.4 E(85289): 2.9e-107
Smith-Waterman score: 1658; 66.9% identity (84.7% similar) in 378 aa overlap (1-374:1-376)
10 20 30 40 50 60
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
:: : :::::::..:.: ::. :::.::::::::.: :::::.:::::.:::::.: : .
NP_001 MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF
10 20 30 40 50
70 80 90 100 110
pF1KB6 YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE
:.: :::.::::::.:::.:::::::: ::::::::.:::: .:.. ::::::::.:
NP_001 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR
::.: .:. ::::: ::::::::::.:.:. :.:::::.::::::.::.:.:.::::.
NP_001 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT
. :. :::... :.: ::::::.. :: : :. ::.: :::: .::.:.:.:::..:
NP_001 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK
:: .::: :::::: :: . . . .:.: :::.:::::::.: :: ::: :::. .:
NP_001 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF
::::::: . .. ::::.:: ::::::::::::::::.. ::.:. ::::::::::::
NP_001 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF
300 310 320 330 340 350
360 370
pF1KB6 IRHHKTNCILFCGRFSSP
:.: ::: ::::::::::
NP_001 IQHSKTNGILFCGRFSSP
360 370
>>XP_011512975 (OMIM: 173321,613453) PREDICTED: serpin B (376 aa)
initn: 1100 init1: 833 opt: 1658 Z-score: 2046.6 bits: 387.4 E(85289): 2.9e-107
Smith-Waterman score: 1658; 66.9% identity (84.7% similar) in 378 aa overlap (1-374:1-376)
10 20 30 40 50 60
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
:: : :::::::..:.: ::. :::.::::::::.: :::::.:::::.:::::.: : .
XP_011 MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF
10 20 30 40 50
70 80 90 100 110
pF1KB6 YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE
:.: :::.::::::.:::.:::::::: ::::::::.:::: .:.. ::::::::.:
XP_011 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR
::.: .:. ::::: ::::::::::.:.:. :.:::::.::::::.::.:.:.::::.
XP_011 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT
. :. :::... :.: ::::::.. :: : :. ::.: :::: .::.:.:.:::..:
XP_011 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK
:: .::: :::::: :: . . . .:.: :::.:::::::.: :: ::: :::. .:
XP_011 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF
::::::: . .. ::::.:: ::::::::::::::::.. ::.:. ::::::::::::
XP_011 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF
300 310 320 330 340 350
360 370
pF1KB6 IRHHKTNCILFCGRFSSP
:.: ::: ::::::::::
XP_011 IQHSKTNGILFCGRFSSP
360 370
>>NP_004559 (OMIM: 173321,613453) serpin B6 isoform a [H (376 aa)
initn: 1100 init1: 833 opt: 1658 Z-score: 2046.6 bits: 387.4 E(85289): 2.9e-107
Smith-Waterman score: 1658; 66.9% identity (84.7% similar) in 378 aa overlap (1-374:1-376)
10 20 30 40 50 60
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
:: : :::::::..:.: ::. :::.::::::::.: :::::.:::::.:::::.: : .
NP_004 MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF
10 20 30 40 50
70 80 90 100 110
pF1KB6 YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE
:.: :::.::::::.:::.:::::::: ::::::::.:::: .:.. ::::::::.:
NP_004 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR
::.: .:. ::::: ::::::::::.:.:. :.:::::.::::::.::.:.:.::::.
NP_004 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT
. :. :::... :.: ::::::.. :: : :. ::.: :::: .::.:.:.:::..:
NP_004 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK
:: .::: :::::: :: . . . .:.: :::.:::::::.: :: ::: :::. .:
NP_004 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF
::::::: . .. ::::.:: ::::::::::::::::.. ::.:. ::::::::::::
NP_004 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF
300 310 320 330 340 350
360 370
pF1KB6 IRHHKTNCILFCGRFSSP
:.: ::: ::::::::::
NP_004 IQHSKTNGILFCGRFSSP
360 370
>>NP_001258753 (OMIM: 173321,613453) serpin B6 isoform a (376 aa)
initn: 1100 init1: 833 opt: 1658 Z-score: 2046.6 bits: 387.4 E(85289): 2.9e-107
Smith-Waterman score: 1658; 66.9% identity (84.7% similar) in 378 aa overlap (1-374:1-376)
10 20 30 40 50 60
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
:: : :::::::..:.: ::. :::.::::::::.: :::::.:::::.:::::.: : .
NP_001 MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF
10 20 30 40 50
70 80 90 100 110
pF1KB6 YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE
:.: :::.::::::.:::.:::::::: ::::::::.:::: .:.. ::::::::.:
NP_001 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR
::.: .:. ::::: ::::::::::.:.:. :.:::::.::::::.::.:.:.::::.
NP_001 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT
. :. :::... :.: ::::::.. :: : :. ::.: :::: .::.:.:.:::..:
NP_001 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK
:: .::: :::::: :: . . . .:.: :::.:::::::.: :: ::: :::. .:
NP_001 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF
::::::: . .. ::::.:: ::::::::::::::::.. ::.:. ::::::::::::
NP_001 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF
300 310 320 330 340 350
360 370
pF1KB6 IRHHKTNCILFCGRFSSP
:.: ::: ::::::::::
NP_001 IQHSKTNGILFCGRFSSP
360 370
>>NP_001284628 (OMIM: 173321,613453) serpin B6 isoform a (376 aa)
initn: 1100 init1: 833 opt: 1658 Z-score: 2046.6 bits: 387.4 E(85289): 2.9e-107
Smith-Waterman score: 1658; 66.9% identity (84.7% similar) in 378 aa overlap (1-374:1-376)
10 20 30 40 50 60
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
:: : :::::::..:.: ::. :::.::::::::.: :::::.:::::.:::::.: : .
NP_001 MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF
10 20 30 40 50
70 80 90 100 110
pF1KB6 YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE
:.: :::.::::::.:::.:::::::: ::::::::.:::: .:.. ::::::::.:
NP_001 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR
::.: .:. ::::: ::::::::::.:.:. :.:::::.::::::.::.:.:.::::.
NP_001 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT
. :. :::... :.: ::::::.. :: : :. ::.: :::: .::.:.:.:::..:
NP_001 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK
:: .::: :::::: :: . . . .:.: :::.:::::::.: :: ::: :::. .:
NP_001 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF
::::::: . .. ::::.:: ::::::::::::::::.. ::.:. ::::::::::::
NP_001 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF
300 310 320 330 340 350
360 370
pF1KB6 IRHHKTNCILFCGRFSSP
:.: ::: ::::::::::
NP_001 IQHSKTNGILFCGRFSSP
360 370
>>NP_001284629 (OMIM: 173321,613453) serpin B6 isoform a (376 aa)
initn: 1100 init1: 833 opt: 1658 Z-score: 2046.6 bits: 387.4 E(85289): 2.9e-107
Smith-Waterman score: 1658; 66.9% identity (84.7% similar) in 378 aa overlap (1-374:1-376)
10 20 30 40 50 60
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
:: : :::::::..:.: ::. :::.::::::::.: :::::.:::::.:::::.: : .
NP_001 MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF
10 20 30 40 50
70 80 90 100 110
pF1KB6 YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE
:.: :::.::::::.:::.:::::::: ::::::::.:::: .:.. ::::::::.:
NP_001 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR
::.: .:. ::::: ::::::::::.:.:. :.:::::.::::::.::.:.:.::::.
NP_001 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT
. :. :::... :.: ::::::.. :: : :. ::.: :::: .::.:.:.:::..:
NP_001 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK
:: .::: :::::: :: . . . .:.: :::.:::::::.: :: ::: :::. .:
NP_001 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF
::::::: . .. ::::.:: ::::::::::::::::.. ::.:. ::::::::::::
NP_001 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF
300 310 320 330 340 350
360 370
pF1KB6 IRHHKTNCILFCGRFSSP
:.: ::: ::::::::::
NP_001 IQHSKTNGILFCGRFSSP
360 370
>>NP_001182220 (OMIM: 173321,613453) serpin B6 isoform b (380 aa)
initn: 1100 init1: 833 opt: 1658 Z-score: 2046.5 bits: 387.4 E(85289): 3e-107
Smith-Waterman score: 1658; 66.9% identity (84.7% similar) in 378 aa overlap (1-374:5-380)
10 20 30 40 50
pF1KB6 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQ
:: : :::::::..:.: ::. :::.::::::::.: :::::.:::::.:::::.:
NP_001 MSAIMDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 ALCLYKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQ
: . :.: :::.::::::.:::.:::::::: ::::::::.:::: .:.. ::::::
NP_001 ILSFNKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 AELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNE
::.:::.: .:. ::::: ::::::::::.:.:. :.:::::.::::::.::.:.:.:
NP_001 AEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 QFDRKYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLP
:::.. :. :::... :.: ::::::.. :: : :. ::.: :::: .::.:.:.::
NP_001 QFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 DDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAF
:..::: .::: :::::: :: . . . .:.: :::.:::::::.: :: ::: :::
NP_001 DETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 DEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHP
. .:::::::: . .. ::::.:: ::::::::::::::::.. ::.:. ::::::::
NP_001 ELGKADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHP
300 310 320 330 340 350
360 370
pF1KB6 FLFFIRHHKTNCILFCGRFSSP
:::::.: ::: ::::::::::
NP_001 FLFFIQHSKTNGILFCGRFSSP
360 370 380
374 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:52:49 2016 done: Fri Nov 4 15:52:50 2016
Total Scan time: 7.080 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]