Result of FASTA (omim) for
pF1KB6572
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6572, 400 aa
1>>>pF1KB6572 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1181+/-0.000394; mu= 19.0651+/- 0.025
mean_var=109.6049+/-28.386, 0's: 0 Z-trim(113.1): 479 B-trim: 2345 in 2/51
Lambda= 0.122507
statistics sampled from 21528 (22226) to 21528 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.261), width: 16
Scan time: 8.740
The best scores are: opt bits E(85289)
XP_016861318 (OMIM: 126451,181500,190300) PREDICTE ( 400) 2660 481.4 1.7e-135
NP_001277738 (OMIM: 126451,181500,190300) D(3) dop ( 400) 2660 481.4 1.7e-135
NP_000787 (OMIM: 126451,181500,190300) D(3) dopami ( 400) 2660 481.4 1.7e-135
NP_001269492 (OMIM: 126451,181500,190300) D(3) dop ( 400) 2660 481.4 1.7e-135
NP_387512 (OMIM: 126451,181500,190300) D(3) dopami ( 367) 1910 348.8 1.3e-95
XP_016872785 (OMIM: 126450,159900) PREDICTED: D(2) ( 443) 898 170.0 9.8e-42
NP_000786 (OMIM: 126450,159900) D(2) dopamine rece ( 443) 898 170.0 9.8e-42
NP_057658 (OMIM: 126450,159900) D(2) dopamine rece ( 414) 896 169.6 1.2e-41
NP_000788 (OMIM: 126452,143465,601696) D(4) dopami ( 419) 596 116.6 1.1e-25
NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamin ( 422) 487 97.4 7e-20
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 478 95.6 1.7e-19
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 478 95.6 1.8e-19
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 478 95.6 1.8e-19
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 478 95.7 1.9e-19
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 478 95.7 1.9e-19
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372) 478 95.7 2e-19
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 468 94.1 7.6e-19
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 467 93.9 8.3e-19
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 467 93.9 8.4e-19
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 467 93.9 8.8e-19
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 455 91.8 3.7e-18
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 452 91.1 4.4e-18
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 452 91.1 4.4e-18
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366) 452 91.1 4.7e-18
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450) 453 91.4 4.7e-18
XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B ad ( 389) 452 91.1 4.9e-18
XP_011532739 (OMIM: 104220) PREDICTED: alpha-1B ad ( 402) 452 91.2 5e-18
XP_011532737 (OMIM: 104220) PREDICTED: alpha-1B ad ( 556) 452 91.3 6.1e-18
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 431 87.4 6.4e-17
NP_000859 (OMIM: 312861) 5-hydroxytryptamine recep ( 458) 431 87.5 7e-17
NP_001243689 (OMIM: 312861) 5-hydroxytryptamine re ( 458) 431 87.5 7e-17
NP_000612 (OMIM: 103780,164230,181500,182135,60678 ( 471) 410 83.8 9.4e-16
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 385 79.4 2e-14
NP_076917 (OMIM: 601305) 5-hydroxytryptamine recep ( 357) 382 78.7 2.4e-14
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 380 78.4 3.4e-14
NP_001307687 (OMIM: 601122) 5-hydroxytryptamine re ( 439) 373 77.2 8.4e-14
XP_006712545 (OMIM: 601122) PREDICTED: 5-hydroxytr ( 456) 373 77.3 8.6e-14
NP_000858 (OMIM: 601122) 5-hydroxytryptamine recep ( 481) 373 77.3 8.9e-14
NP_000785 (OMIM: 126449) D(1A) dopamine receptor [ ( 446) 372 77.1 9.5e-14
NP_000789 (OMIM: 126453,143465,606798) D(1B) dopam ( 477) 361 75.2 3.8e-13
NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 357 74.4 5.9e-13
NP_000729 (OMIM: 118510) muscarinic acetylcholine ( 460) 344 72.1 3e-12
XP_011543044 (OMIM: 118510) PREDICTED: muscarinic ( 460) 344 72.1 3e-12
XP_011536797 (OMIM: 606383) PREDICTED: G-protein c ( 396) 334 70.3 9.3e-12
NP_065103 (OMIM: 606383) G-protein coupled recepto ( 396) 334 70.3 9.3e-12
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 326 68.8 2.3e-11
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360) 325 68.7 2.6e-11
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378) 325 68.7 2.7e-11
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387) 325 68.7 2.8e-11
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 325 68.7 2.8e-11
>>XP_016861318 (OMIM: 126451,181500,190300) PREDICTED: D (400 aa)
initn: 2660 init1: 2660 opt: 2660 Z-score: 2553.8 bits: 481.4 E(85289): 1.7e-135
Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
310 320 330 340 350 360
370 380 390 400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
::::::::::::::::::::::::::::::::::::::::
XP_016 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
370 380 390 400
>>NP_001277738 (OMIM: 126451,181500,190300) D(3) dopamin (400 aa)
initn: 2660 init1: 2660 opt: 2660 Z-score: 2553.8 bits: 481.4 E(85289): 1.7e-135
Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
310 320 330 340 350 360
370 380 390 400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
::::::::::::::::::::::::::::::::::::::::
NP_001 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
370 380 390 400
>>NP_000787 (OMIM: 126451,181500,190300) D(3) dopamine r (400 aa)
initn: 2660 init1: 2660 opt: 2660 Z-score: 2553.8 bits: 481.4 E(85289): 1.7e-135
Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
310 320 330 340 350 360
370 380 390 400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
::::::::::::::::::::::::::::::::::::::::
NP_000 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
370 380 390 400
>>NP_001269492 (OMIM: 126451,181500,190300) D(3) dopamin (400 aa)
initn: 2660 init1: 2660 opt: 2660 Z-score: 2553.8 bits: 481.4 E(85289): 1.7e-135
Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
310 320 330 340 350 360
370 380 390 400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
::::::::::::::::::::::::::::::::::::::::
NP_001 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
370 380 390 400
>>NP_387512 (OMIM: 126451,181500,190300) D(3) dopamine r (367 aa)
initn: 1910 init1: 1910 opt: 1910 Z-score: 1837.8 bits: 348.8 E(85289): 1.3e-95
Smith-Waterman score: 2372; 91.5% identity (91.8% similar) in 400 aa overlap (1-400:1-367)
10 20 30 40 50 60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
::::::::::::::::::::::::::::::::::::::::::::::
NP_387 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSL--------------
250 260 270 280
310 320 330 340 350 360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
.::::::::::::::::::::::::::::::::::::::::
NP_387 -------------------MPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
290 300 310 320
370 380 390 400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
::::::::::::::::::::::::::::::::::::::::
NP_387 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
330 340 350 360
>>XP_016872785 (OMIM: 126450,159900) PREDICTED: D(2) dop (443 aa)
initn: 1091 init1: 303 opt: 898 Z-score: 870.2 bits: 170.0 E(85289): 9.8e-42
Smith-Waterman score: 1245; 53.4% identity (71.1% similar) in 425 aa overlap (19-394:23-437)
10 20 30 40 50
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPH-AYYALSYCALILAIVFGNGLVCMAVL
:.. .. ::: ::: :: .::::: ::::::
XP_016 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 KERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCT
.:.:::::::::.:::::::::::::::::::::::.: :.:::: ::.::::::::::
XP_016 REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGE-WKFSRIHCDIFVTLDVMMCT
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTT
:::::::::::::::::.::. :. : :: :::..::. ::::.:..:::::::.:..
XP_016 ASILNLCAISIDRYTAVAMPMLYN--TRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 GDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQC----
: . : :.:: ::.:::.::::.:: ::.::: .::.::. :::::. :...:.
XP_016 -DQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLR-RRRKRVNTKRSSRAFRAH
180 190 200 210 220 230
240 250
pF1KB6 -------NSVRP--------------GFPQQTLSPDPAH----LELK-----------RY
: ..: .:: . . :. ::.. ::
XP_016 LRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRY
240 250 260 270 280 290
260 270 280 290 300
pF1KB6 YSI---CQDTALGGP---GFQERGGELKREEKTRNSLS-PTIAPKLSLEVRKLSNGRLST
: .. .: : :.. . ::. .. . : :: :. .:.. . ::. :
XP_016 SPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIA-KI-FEIQTMPNGKTRT
300 310 320 330 340 350
310 320 330 340 350 360
pF1KB6 SLKLGPLQPRGVPL-REKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSA
::: .. : . .:::::::.:::::.::.::::::.::.:: ::. :.. : ::::
XP_016 SLKT--MSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCD-CNIPPVLYSA
360 370 380 390 400 410
370 380 390 400
pF1KB6 TTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
:::::::::.::.:::::::::::::
XP_016 FTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
420 430 440
>>NP_000786 (OMIM: 126450,159900) D(2) dopamine receptor (443 aa)
initn: 1091 init1: 303 opt: 898 Z-score: 870.2 bits: 170.0 E(85289): 9.8e-42
Smith-Waterman score: 1245; 53.4% identity (71.1% similar) in 425 aa overlap (19-394:23-437)
10 20 30 40 50
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPH-AYYALSYCALILAIVFGNGLVCMAVL
:.. .. ::: ::: :: .::::: ::::::
NP_000 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 KERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCT
.:.:::::::::.:::::::::::::::::::::::.: :.:::: ::.::::::::::
NP_000 REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGE-WKFSRIHCDIFVTLDVMMCT
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTT
:::::::::::::::::.::. :. : :: :::..::. ::::.:..:::::::.:..
NP_000 ASILNLCAISIDRYTAVAMPMLYN--TRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 GDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQC----
: . : :.:: ::.:::.::::.:: ::.::: .::.::. :::::. :...:.
NP_000 -DQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLR-RRRKRVNTKRSSRAFRAH
180 190 200 210 220 230
240 250
pF1KB6 -------NSVRP--------------GFPQQTLSPDPAH----LELK-----------RY
: ..: .:: . . :. ::.. ::
NP_000 LRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRY
240 250 260 270 280 290
260 270 280 290 300
pF1KB6 YSI---CQDTALGGP---GFQERGGELKREEKTRNSLS-PTIAPKLSLEVRKLSNGRLST
: .. .: : :.. . ::. .. . : :: :. .:.. . ::. :
NP_000 SPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIA-KI-FEIQTMPNGKTRT
300 310 320 330 340 350
310 320 330 340 350 360
pF1KB6 SLKLGPLQPRGVPL-REKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSA
::: .. : . .:::::::.:::::.::.::::::.::.:: ::. :.. : ::::
NP_000 SLKT--MSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCD-CNIPPVLYSA
360 370 380 390 400 410
370 380 390 400
pF1KB6 TTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
:::::::::.::.:::::::::::::
NP_000 FTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
420 430 440
>>NP_057658 (OMIM: 126450,159900) D(2) dopamine receptor (414 aa)
initn: 1057 init1: 303 opt: 896 Z-score: 868.7 bits: 169.6 E(85289): 1.2e-41
Smith-Waterman score: 1323; 56.7% identity (75.1% similar) in 402 aa overlap (19-400:23-414)
10 20 30 40 50
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPH-AYYALSYCALILAIVFGNGLVCMAVL
:.. .. ::: ::: :: .::::: ::::::
NP_057 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 KERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCT
.:.:::::::::.:::::::::::::::::::::::.: :.:::: ::.::::::::::
NP_057 REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGE-WKFSRIHCDIFVTLDVMMCT
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTT
:::::::::::::::::.::. : .: :: :::..::. ::::.:..:::::::.:..
NP_057 ASILNLCAISIDRYTAVAMPMLY--NTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 GDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVR
: . : :.:: ::.:::.::::.:: ::.::: .::.::. :::::. :...:. ..
NP_057 -DQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLR-RRRKRVNTKRSSRAFRAH
180 190 200 210 220 230
240 250 260 270
pF1KB6 PGFPQQTLSPDPAHLELK-----------RYYSI---CQDTALGGP---GFQERGGELKR
: . . .::.. :: : .. .: : :.. .
NP_057 LRAPLKEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAK
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 EEKTRNSLS-PTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPL-REKKATQMVAIVLG
::. .. . : :: :. .:.. . ::. :::: .. : . .:::::::.:::::
NP_057 PEKNGHAKDHPKIA-KI-FEIQTMPNGKTRTSLK--TMSRRKLSQQKEKKATQMLAIVLG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 AFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLK
.::.::::::.::.:: ::. :.. : :::: :::::::::.::.:::::::::::::::
NP_057 VFIICWLPFFITHILNIHCD-CNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLK
360 370 380 390 400 410
400
pF1KB6 ILSC
:: :
NP_057 ILHC
>>NP_000788 (OMIM: 126452,143465,601696) D(4) dopamine r (419 aa)
initn: 871 init1: 403 opt: 596 Z-score: 582.0 bits: 116.6 E(85289): 1.1e-25
Smith-Waterman score: 884; 40.9% identity (63.7% similar) in 408 aa overlap (16-400:21-418)
10 20 30 40 50
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVL
:: ...:. : : .. :: :.. ::.:::..:
NP_000 MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 KERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCT
:::::: :: ..::::.::::.: ::.: :: :: ::.: .: ::.....:::.::
NP_000 TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 ASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTT
:::.::::::.::..::..:..:.. :.. :: :.: :.:.:. ::. :.: :.: .
NP_000 ASIFNLCAISVDRFVAVAVPLRYNR---QGGSRRQLLLIGATWLLSAAVAAPVLCGLNDV
130 140 150 160 170
180 190 200 210 220 230
pF1KB6 -G-DPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQ---RRRKRILTRQNSQ
: ::.:: . . :.:.:::: ::.:: . .:.: . :.. :: .. : .
NP_000 RGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRR
180 190 200 210 220 230
240 250 260 270 280
pF1KB6 CNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALG------GPGFQERGGELKREEKTRN
.. :: :. : : : .: : : : :: . : .. .
NP_000 PSG--PGPPSPT-PPAP-RLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPD
240 250 260 270 280 290
290 300 310 320 330
pF1KB6 SLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPL-----------REKKATQMVAI
: :: : . :: ... . : :. : ::.:: ... .
NP_000 CAPP--APGLPPDPCG-SNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPV
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 VLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKA
:.:::..:: :::..:. .. : .: : :.: ::.::::::::::::::::.:: :::..
NP_000 VVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNV
360 370 380 390 400 410
400
pF1KB6 FLKIL-SC
: : : .:
NP_000 FRKALRACC
>>NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamine re (422 aa)
initn: 602 init1: 185 opt: 487 Z-score: 477.9 bits: 97.4 E(85289): 7e-20
Smith-Waterman score: 734; 32.8% identity (65.7% similar) in 408 aa overlap (19-400:24-417)
10 20 30 40 50
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARP--HAYYALSYCALILAIVFGNGLVCMA
:.:: :.. .. .: .::. :.::. : :
NP_000 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 VLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMM
. ::.::...:::. ::::.::.:..::.: .. .: . :..... ::.:..:::.
NP_000 IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNK-WTLGQVTCDLFIALDVLC
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 CTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFN
::.:::.::::..::: :.. :. : ... . ::.: .:. .:...: .: : ..:.
NP_000 CTSSILHLCAIALDRYWAITDPIDY---VNKRTPRRAAALISLTWLIGFLISIPPMLGWR
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 TT---GDPTVCSIS-NPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNS
: .:: .:.:: . ..:::. .::.:. . ...:.::. . . : :: . ...
NP_000 TPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKT
180 190 200 210 220 230
230 240 250 260 270
pF1KB6 QCNSVRPGF-----PQQTLSPDPAH------LELKRYYSICQDTAL--GGPGFQERGGEL
.. : : :..... . . .: : ..: . :. : : . :.
NP_000 GADT-RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 KREEKTRNSL------SPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQM
.: .... : .:: :.: .. :.. . .. :. ::.:...
NP_000 HRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALA---------RERKTVKT
300 310 320 330 340
340 350 360 370 380
pF1KB6 VAIVLGAFIVCWLPFFLTHVLNTHCQT-CHVSPELYSATTWLGYVNSALNPVIYTTFNIE
..:..:.::.::::::.. .. :.. ::. : . .:::: :: ::::::. :: .
NP_000 LGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKD
350 360 370 380 390 400
390 400
pF1KB6 FRKAFLKILSC
:..:: ::..:
NP_000 FQNAFKKIIKCKFCRQ
410 420
400 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:12:31 2016 done: Sat Nov 5 18:12:33 2016
Total Scan time: 8.740 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]