FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6574, 401 aa 1>>>pF1KB6574 401 - 401 aa - 401 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2362+/-0.000439; mu= 13.9237+/- 0.027 mean_var=147.4168+/-29.388, 0's: 0 Z-trim(115.2): 101 B-trim: 47 in 1/50 Lambda= 0.105633 statistics sampled from 25454 (25569) to 25454 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.3), width: 16 Scan time: 5.980 The best scores are: opt bits E(85289) NP_002537 (OMIM: 239000,602643) tumor necrosis fac ( 401) 2812 440.6 3.2e-123 NP_003814 (OMIM: 603361) tumor necrosis factor rec ( 300) 597 102.9 1.1e-21 NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461) 455 81.5 4.8e-15 XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462) 455 81.5 4.8e-15 XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484) 455 81.5 4.9e-15 XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491) 455 81.5 5e-15 XP_016857702 (OMIM: 191191) PREDICTED: tumor necro ( 440) 442 79.5 1.8e-14 XP_016857701 (OMIM: 191191) PREDICTED: tumor necro ( 440) 442 79.5 1.8e-14 XP_016866233 (OMIM: 605732) PREDICTED: tumor necro ( 444) 417 75.6 2.6e-13 NP_055267 (OMIM: 605732) tumor necrosis factor rec ( 655) 417 75.8 3.3e-13 NP_001257880 (OMIM: 174810,602080,603499,612301) t ( 299) 384 70.4 6.5e-12 NP_001257878 (OMIM: 174810,602080,603499,612301) t ( 263) 383 70.2 6.6e-12 NP_001257879 (OMIM: 174810,602080,603499,612301) t ( 337) 383 70.3 7.8e-12 NP_003830 (OMIM: 174810,602080,603499,612301) tumo ( 616) 383 70.6 1.2e-11 NP_001289682 (OMIM: 109535,606843) tumor necrosis ( 237) 371 68.3 2.2e-11 XP_016883626 (OMIM: 109535,606843) PREDICTED: tumo ( 222) 370 68.1 2.3e-11 XP_016883624 (OMIM: 109535,606843) PREDICTED: tumo ( 323) 371 68.5 2.7e-11 NP_001241 (OMIM: 109535,606843) tumor necrosis fac ( 277) 370 68.3 2.7e-11 NP_001309350 (OMIM: 109535,606843) tumor necrosis ( 281) 370 68.3 2.7e-11 XP_011524546 (OMIM: 174810,602080,603499,612301) P ( 621) 372 69.0 3.7e-11 XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255) 339 63.5 6.7e-10 XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399) 339 63.7 9.1e-10 NP_001257916 (OMIM: 600979) tumor necrosis factor ( 416) 339 63.7 9.3e-10 NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435) 339 63.7 9.6e-10 NP_690593 (OMIM: 109535,606843) tumor necrosis fac ( 203) 332 62.3 1.2e-09 XP_016883625 (OMIM: 109535,606843) PREDICTED: tumo ( 289) 332 62.5 1.5e-09 NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283) 293 56.5 9.3e-08 XP_016881554 (OMIM: 174810,602080,603499,612301) P ( 566) 291 56.6 1.8e-07 XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197) 276 53.8 4.4e-07 NP_001284534 (OMIM: 602746) tumor necrosis factor ( 184) 269 52.7 8.9e-07 XP_011527411 (OMIM: 109535,606843) PREDICTED: tumo ( 166) 252 50.0 5e-06 NP_001309351 (OMIM: 109535,606843) tumor necrosis ( 225) 250 49.9 7.5e-06 XP_005260676 (OMIM: 109535,606843) PREDICTED: tumo ( 229) 250 49.9 7.6e-06 NP_001265197 (OMIM: 174810,602080,603499,612301) t ( 602) 246 49.7 2.2e-05 NP_001056 (OMIM: 142680,191190,614810) tumor necro ( 455) 233 47.6 7.2e-05 XP_011540743 (OMIM: 153243) PREDICTED: tumor necro ( 594) 229 47.1 0.00013 NP_001234 (OMIM: 153243) tumor necrosis factor rec ( 595) 229 47.1 0.00013 NP_001307548 (OMIM: 134637,601859) tumor necrosis ( 197) 219 45.1 0.00018 NP_690611 (OMIM: 134637,601859) tumor necrosis fac ( 220) 219 45.1 0.0002 NP_003831 (OMIM: 603614) tumor necrosis factor rec ( 386) 218 45.3 0.00032 NP_003832 (OMIM: 603613) tumor necrosis factor rec ( 259) 214 44.4 0.00037 NP_002498 (OMIM: 162010) tumor necrosis factor rec ( 427) 205 43.3 0.0013 NP_683700 (OMIM: 603905) tumor necrosis factor rec ( 234) 195 41.5 0.0026 NP_004186 (OMIM: 603905) tumor necrosis factor rec ( 241) 194 41.4 0.0029 NP_003318 (OMIM: 600315,615593) tumor necrosis fac ( 277) 193 41.3 0.0036 XP_016857721 (OMIM: 600315,615593) PREDICTED: tumo ( 277) 193 41.3 0.0036 XP_016858211 (OMIM: 603905) PREDICTED: tumor necro ( 347) 194 41.5 0.0037 XP_011540377 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 193 41.3 0.0038 XP_016857720 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 193 41.3 0.0038 NP_003835 (OMIM: 603611) tumor necrosis factor rec ( 468) 192 41.4 0.0056 >>NP_002537 (OMIM: 239000,602643) tumor necrosis factor (401 aa) initn: 2812 init1: 2812 opt: 2812 Z-score: 2333.2 bits: 440.6 E(85289): 3.2e-123 Smith-Waterman score: 2812; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401) 10 20 30 40 50 60 pF1KB6 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNAT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 HDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 KRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLME 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SLPGKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALKHSKTYHFPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SLPGKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALKHSKTYHFPKT 310 320 330 340 350 360 370 380 390 400 pF1KB6 VTQSLKKTIRFLHSFTMYKLYQKLFLEMIGNQVQSVKISCL ::::::::::::::::::::::::::::::::::::::::: NP_002 VTQSLKKTIRFLHSFTMYKLYQKLFLEMIGNQVQSVKISCL 370 380 390 400 >>NP_003814 (OMIM: 603361) tumor necrosis factor recepto (300 aa) initn: 637 init1: 564 opt: 597 Z-score: 510.3 bits: 102.9 E(85289): 1.1e-21 Smith-Waterman score: 597; 37.7% identity (64.5% similar) in 231 aa overlap (3-227:10-236) 10 20 30 40 50 pF1KB6 MNNLLCCALVF---LDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYL .::: .:.. : . . :: : : : ::...:.: .:::::.. NP_003 MRALEGPGLSLLCLVLALPALLPVPAVRGVAET--PTYPWRDAETGERLVCAQCPPGTFV 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEG .. : :.:.::: ..::. :. ..: ::. .: : . . :. ::::.:.:. : NP_003 QRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 RYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFG . . :::.: ::::: ::. ::: .:: :. :: : :: .::. :. : ::...: NP_003 FFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALG 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 LLLTQKGNATHDNICS---GNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNL : :. :...::..:. : ::. : . ::.: . :.. .. . :. :.. : NP_003 LALNVPGSSSHDTLCTSCTGFPLSTRVPGAEE--CERAVIDFVAFQDISIKRLQRLLQAL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 PGTKVNAESVERIKRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGH NP_003 EAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERF 240 250 260 270 280 290 >>NP_001057 (OMIM: 191191) tumor necrosis factor recepto (461 aa) initn: 436 init1: 261 opt: 455 Z-score: 391.2 bits: 81.5 E(85289): 4.8e-15 Smith-Waterman score: 455; 39.3% identity (57.7% similar) in 168 aa overlap (30-191:45-206) 10 20 30 40 50 pF1KB6 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWK .::. . :. :.:: :: . : :: NP_001 ELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQ--TAQMCCSKCSPGQHAKVFCTKTSD 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 TVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEI---- ::: : : ::. :. ::: :. :. : : :.: .::.: :. : : . NP_001 TVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQE 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB6 --EFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLL ..: :.: :::::.. :: ..::: : : ::: ::: :: : :.: .. NP_001 GCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAI-- 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB6 TQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVN :::. : .:...: . NP_001 --PGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPS 200 210 220 230 240 >>XP_011540365 (OMIM: 191191) PREDICTED: tumor necrosis (462 aa) initn: 437 init1: 261 opt: 455 Z-score: 391.2 bits: 81.5 E(85289): 4.8e-15 Smith-Waterman score: 455; 39.3% identity (57.7% similar) in 168 aa overlap (30-191:45-206) 10 20 30 40 50 pF1KB6 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWK .::. . :. :.:: :: . : :: XP_011 ELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQ--TAQMCCSKCSPGQHAKVFCTKTSD 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 TVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEI---- ::: : : ::. :. ::: :. :. : : :.: .::.: :. : : . XP_011 TVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQE 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB6 --EFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLL ..: :.: :::::.. :: ..::: : : ::: ::: :: : :.: .. XP_011 GCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAI-- 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB6 TQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVN :::. : .:...: . XP_011 --PGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPS 200 210 220 230 240 >>XP_011540362 (OMIM: 191191) PREDICTED: tumor necrosis (484 aa) initn: 436 init1: 261 opt: 455 Z-score: 390.9 bits: 81.5 E(85289): 4.9e-15 Smith-Waterman score: 455; 39.3% identity (57.7% similar) in 168 aa overlap (30-191:45-206) 10 20 30 40 50 pF1KB6 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWK .::. . :. :.:: :: . : :: XP_011 ELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQ--TAQMCCSKCSPGQHAKVFCTKTSD 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 TVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEI---- ::: : : ::. :. ::: :. :. : : :.: .::.: :. : : . XP_011 TVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQE 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB6 --EFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLL ..: :.: :::::.. :: ..::: : : ::: ::: :: : :.: .. XP_011 GCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAI-- 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB6 TQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVN :::. : .:...: . XP_011 --PGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPS 200 210 220 230 240 >>XP_016857700 (OMIM: 191191) PREDICTED: tumor necrosis (491 aa) initn: 409 init1: 261 opt: 455 Z-score: 390.8 bits: 81.5 E(85289): 5e-15 Smith-Waterman score: 455; 39.3% identity (57.7% similar) in 168 aa overlap (30-191:45-206) 10 20 30 40 50 pF1KB6 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWK .::. . :. :.:: :: . : :: XP_016 ELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQ--TAQMCCSKCSPGQHAKVFCTKTSD 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 TVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEI---- ::: : : ::. :. ::: :. :. : : :.: .::.: :. : : . XP_016 TVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQE 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB6 --EFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLL ..: :.: :::::.. :: ..::: : : ::: ::: :: : :.: .. XP_016 GCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAI-- 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB6 TQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVN :::. : .:...: . XP_016 --PGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPS 200 210 220 230 240 >>XP_016857702 (OMIM: 191191) PREDICTED: tumor necrosis (440 aa) initn: 401 init1: 253 opt: 442 Z-score: 380.7 bits: 79.5 E(85289): 1.8e-14 Smith-Waterman score: 442; 39.6% identity (57.2% similar) in 159 aa overlap (39-191:1-155) 10 20 30 40 50 60 pF1KB6 LVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDH . :.:: :: . : :: ::: : : XP_016 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDS 10 20 30 70 80 90 100 110 120 pF1KB6 YYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEI------EFCLKHR ::. :. ::: :. :. : : :.: .::.: :. : : . ..: : XP_016 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 SCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHD .: :::::.. :: ..::: : : ::: ::: :: : :.: .. :::. : XP_016 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAI----PGNASMD 100 110 120 130 140 190 200 210 220 230 240 pF1KB6 NICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERIKR .:...: . XP_016 AVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGD 150 160 170 180 190 200 >>XP_016857701 (OMIM: 191191) PREDICTED: tumor necrosis (440 aa) initn: 401 init1: 253 opt: 442 Z-score: 380.7 bits: 79.5 E(85289): 1.8e-14 Smith-Waterman score: 442; 39.6% identity (57.2% similar) in 159 aa overlap (39-191:1-155) 10 20 30 40 50 60 pF1KB6 LVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDH . :.:: :: . : :: ::: : : XP_016 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDS 10 20 30 70 80 90 100 110 120 pF1KB6 YYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEI------EFCLKHR ::. :. ::: :. :. : : :.: .::.: :. : : . ..: : XP_016 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 SCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHD .: :::::.. :: ..::: : : ::: ::: :: : :.: .. :::. : XP_016 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAI----PGNASMD 100 110 120 130 140 190 200 210 220 230 240 pF1KB6 NICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERIKR .:...: . XP_016 AVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGD 150 160 170 180 190 200 >>XP_016866233 (OMIM: 605732) PREDICTED: tumor necrosis (444 aa) initn: 475 init1: 378 opt: 417 Z-score: 360.1 bits: 75.6 E(85289): 2.6e-13 Smith-Waterman score: 417; 28.5% identity (50.0% similar) in 288 aa overlap (28-308:54-334) 10 20 30 40 50 pF1KB6 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAK : : :. :.. : ::::: :::...::: XP_016 TMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNT 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB6 WKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEF ::. :: .: . ..: :: : . : : .: : : : . XP_016 SLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNAT 90 100 110 120 130 140 120 130 140 150 160 170 pF1KB6 CLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKG : : :: :.:: . :: ... ::.: : ::. :: :. .:.: .:.. . : XP_016 CAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPG 150 160 170 180 190 200 180 190 200 210 220 230 pF1KB6 NATHDNIC----SGNSESTQKCGIDVTLCEEAFFRFAVPTK-FTPNWLSVLVDNLPGTKV . ::.: : .: .. . : . : . ::.. ..:. .. .:. XP_016 TKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVPKGMN-------STES 210 220 230 240 250 240 250 260 270 280 290 pF1KB6 NAESVERIKRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTF :. . : : : :: : . ..: . . .: .. .. .::: . .. XP_016 NSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQQGPHHRHILKLLPSM 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB6 EQLRSLMESLP--GKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALK : . : : : : : XP_016 EATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLLVLVVIVVCSIRKSSRT 320 330 340 350 360 370 >>NP_055267 (OMIM: 605732) tumor necrosis factor recepto (655 aa) initn: 475 init1: 378 opt: 417 Z-score: 358.1 bits: 75.8 E(85289): 3.3e-13 Smith-Waterman score: 417; 28.5% identity (50.0% similar) in 288 aa overlap (28-308:54-334) 10 20 30 40 50 pF1KB6 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAK : : :. :.. : ::::: :::...::: NP_055 TMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNT 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB6 WKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEF ::. :: .: . ..: :: : . : : .: : : : . NP_055 SLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNAT 90 100 110 120 130 140 120 130 140 150 160 170 pF1KB6 CLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKG : : :: :.:: . :: ... ::.: : ::. :: :. .:.: .:.. . : NP_055 CAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPG 150 160 170 180 190 200 180 190 200 210 220 230 pF1KB6 NATHDNIC----SGNSESTQKCGIDVTLCEEAFFRFAVPTK-FTPNWLSVLVDNLPGTKV . ::.: : .: .. . : . : . ::.. ..:. .. .:. NP_055 TKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVPKGMN-------STES 210 220 230 240 250 240 250 260 270 280 290 pF1KB6 NAESVERIKRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTF :. . : : : :: : . ..: . . .: .. .. .::: . .. NP_055 NSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQQGPHHRHILKLLPSM 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB6 EQLRSLMESLP--GKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALK : . : : : : : NP_055 EATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLLVLVVIVVCSIRKSSRT 320 330 340 350 360 370 401 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:20:35 2016 done: Sat Nov 5 04:20:36 2016 Total Scan time: 5.980 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]