FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6577, 377 aa 1>>>pF1KB6577 377 - 377 aa - 377 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6171+/-0.00118; mu= -0.4419+/- 0.070 mean_var=218.0340+/-47.755, 0's: 0 Z-trim(107.7): 153 B-trim: 0 in 0/52 Lambda= 0.086858 statistics sampled from 9581 (9747) to 9581 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.299), width: 16 Scan time: 2.600 The best scores are: opt bits E(32554) CCDS3092.1 NCK1 gene_id:4690|Hs108|chr3 ( 377) 2556 333.6 1.7e-91 CCDS54644.1 NCK1 gene_id:4690|Hs108|chr3 ( 313) 2075 273.3 2.1e-73 CCDS33266.1 NCK2 gene_id:8440|Hs108|chr2 ( 380) 1794 238.1 9.5e-63 >>CCDS3092.1 NCK1 gene_id:4690|Hs108|chr3 (377 aa) initn: 2556 init1: 2556 opt: 2556 Z-score: 1756.1 bits: 333.6 E(32554): 1.7e-91 Smith-Waterman score: 2556; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB6 MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 REDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 REDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 AVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 AVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 LVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 HEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 HEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAP 310 320 330 340 350 360 370 pF1KB6 IFTSEQGEKLYLVKHLS ::::::::::::::::: CCDS30 IFTSEQGEKLYLVKHLS 370 >>CCDS54644.1 NCK1 gene_id:4690|Hs108|chr3 (313 aa) initn: 2075 init1: 2075 opt: 2075 Z-score: 1431.4 bits: 273.3 E(32554): 2.1e-73 Smith-Waterman score: 2075; 98.7% identity (99.7% similar) in 307 aa overlap (71-377:7-313) 50 60 70 80 90 100 pF1KB6 VRNSMNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDP .:: ..:::::::::::::::::::::::: CCDS54 MDWLNVFKDFFSIGKVKRKPSVPDSASPADDSFVDP 10 20 30 110 120 130 140 150 160 pF1KB6 GERLYDLNMPAYVKFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GERLYDLNMPAYVKFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYV 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 TEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVI 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 EKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGN 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 PWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYC 220 230 240 250 260 270 350 360 370 pF1KB6 IGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS ::::::::::::::::::::::::::::::::::::: CCDS54 IGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS 280 290 300 310 >>CCDS33266.1 NCK2 gene_id:8440|Hs108|chr2 (380 aa) initn: 1814 init1: 731 opt: 1794 Z-score: 1240.0 bits: 238.1 E(32554): 9.5e-63 Smith-Waterman score: 1794; 69.4% identity (87.4% similar) in 382 aa overlap (1-376:1-379) 10 20 30 40 50 60 pF1KB6 MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKN :.:::.:.::.::.:::.::::::::::::::::::.::::::. :.::.:::::::::: CCDS33 MTEEVIVIAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKN 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 SARKASIVKNLKDTLGIGKVKRKPSVPD-SASPADDS-FVDPG---ERLYDLNMPAYVKF : .:.:.:::::::::.::..:: :. : : .:. :. . : .:.::::.::.::: CCDS33 SLKKGSLVKNLKDTLGLGKTRRKTSARDASPTPSTDAEYPANGSGADRIYDLNIPAFVKF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 NYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSL :.:::::::::.::..: :::::::::::::::::.:::::::: :: : .. . : CCDS33 AYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAAAESPSFL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 SEKLAAVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKI : . .: ..: . ..::::::.:::::: ..::::::::..:.::::::::::::::.. CCDS33 SLRKGASLSNGQGSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 NGMVGLVPKNYVTVMQNNPLTSGLEPS-PPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEM :.:::::::::.:....: .:.:. :: .: :: .:.::: ::::.::::::: CCDS33 RGQVGLVPKNYVVVLSDGP---ALHPAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAEC 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 ALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVE :::::: :::::::::::::.::::::::.:::::::::: ..:::::::.: ::.:::: CCDS33 ALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVE 300 310 320 330 340 350 360 370 pF1KB6 HYKKAPIFTSEQGEKLYLVKHLS :::::::::::.:::::::. : CCDS33 HYKKAPIFTSEHGEKLYLVRALQ 360 370 380 377 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:18:39 2016 done: Sat Nov 5 01:18:39 2016 Total Scan time: 2.600 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]