FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6578, 402 aa 1>>>pF1KB6578 402 - 402 aa - 402 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9063+/-0.000814; mu= 16.3288+/- 0.049 mean_var=109.2149+/-21.691, 0's: 0 Z-trim(111.5): 102 B-trim: 72 in 1/51 Lambda= 0.122725 statistics sampled from 12287 (12394) to 12287 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.381), width: 16 Scan time: 3.240 The best scores are: opt bits E(32554) CCDS43868.1 BSPRY gene_id:54836|Hs108|chr9 ( 402) 2720 492.0 4.2e-139 CCDS34378.1 TRIM39 gene_id:56658|Hs108|chr6 ( 488) 363 74.7 2.1e-13 CCDS32437.1 TRIM72 gene_id:493829|Hs108|chr16 ( 477) 337 70.1 4.9e-12 CCDS4677.1 TRIM15 gene_id:89870|Hs108|chr6 ( 465) 324 67.8 2.4e-11 CCDS34654.1 TRIM50 gene_id:135892|Hs108|chr7 ( 487) 318 66.7 5.2e-11 >>CCDS43868.1 BSPRY gene_id:54836|Hs108|chr9 (402 aa) initn: 2720 init1: 2720 opt: 2720 Z-score: 2610.7 bits: 492.0 E(32554): 4.2e-139 Smith-Waterman score: 2720; 99.8% identity (99.8% similar) in 402 aa overlap (1-402:1-402) 10 20 30 40 50 60 pF1KB6 MSAEGAEPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MSAEGAEPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ERAEELRNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ERAEELRNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 CESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 GVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDL 310 320 330 340 350 360 370 380 390 400 pF1KB6 QVQELLFYEPASGIVLCAHHVSFPGPLFPVFAVADQTISIVR ::::::::::::: :::::::::::::::::::::::::::: CCDS43 QVQELLFYEPASGTVLCAHHVSFPGPLFPVFAVADQTISIVR 370 380 390 400 >>CCDS34378.1 TRIM39 gene_id:56658|Hs108|chr6 (488 aa) initn: 329 init1: 194 opt: 363 Z-score: 354.3 bits: 74.7 E(32554): 2.1e-13 Smith-Waterman score: 378; 25.1% identity (54.1% similar) in 379 aa overlap (21-391:106-465) 10 20 30 40 50 pF1KB6 MSAEGAEPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGR :::.: .::: :: ... :: :: .. CCDS34 RSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICA-ISHT 80 90 100 110 120 130 60 70 80 90 100 pF1KB6 CRGHRIRRAEERAEELRNKIVDQC-ERLQLQSAAIT--KYVADVLPGKNQRAVSMASAAR :.: . .. ..: ..:. ..: : :. . :: : . ::. .: : . : CCDS34 HRAHTVVPLDDATQEYKEKL-QKCLEPLEQKLQEITRCKSSEEKKPGELKRLV---ESRR 140 150 160 170 180 190 110 120 130 140 150 160 pF1KB6 ELVIQRLSLVRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVG- . ..... .. . :.: :: ... ::. : . . .: .. . : . . . : CCDS34 QQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGK 200 210 220 230 240 250 170 180 190 200 210 220 pF1KB6 -MLTHLDDLQLIQKEQEIFER--TEEAEGILDPQESEMLNFNEK-CTRSPLLTQLWATAV . . .. :. ... : :. : :. .. :... :: .. . .: :: : CCDS34 CLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIA--- 260 270 280 290 300 230 240 250 260 270 280 pF1KB6 LGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQ :. .: .:. : : ::.:::.. : . . : :.:: .: .::. .: CCDS34 --------DVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFT 310 320 330 340 350 290 300 310 320 330 340 pF1KB6 NGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQH .: : : :.: .. . ::: . ::: . : .... : .. . . . CCDS34 SGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTP--LPETGY-WRVRLWNGDKYAATTTPF 360 370 380 390 400 410 350 360 370 380 390 400 pF1KB6 EPLGLLRGPAQLGVVLDLQVQELLFYEPASGIVLCAHHVSFPGPLFPVFAVADQTISIVR :: . : ..:. :: .. : ::. .. . . .: :.:.: CCDS34 TPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNA 420 430 440 450 460 470 CCDS34 APLTIRPPTDWE 480 >>CCDS32437.1 TRIM72 gene_id:493829|Hs108|chr16 (477 aa) initn: 96 init1: 96 opt: 337 Z-score: 329.5 bits: 70.1 E(32554): 4.9e-12 Smith-Waterman score: 345; 24.9% identity (54.8% similar) in 389 aa overlap (18-393:82-455) 10 20 30 40 pF1KB6 MSAEGAEPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGL : : :: . :: .: ..: ::..::.: CCDS32 LCPCCQAPTRPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASL 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB6 GGRCRGHRIRRAEERAEELRNKIVDQCERLQLQSAAITKYVA-DVLPGKNQRAVSMASAA :.. ::::. : : .:.... .: .:::: : . : . :: . .. . CCDS32 GSH-RGHRLLPAAEAHARLKTQLPQQ--KLQLQEACMRKEKSVAVLEHQLVEVEETVRQF 120 130 140 150 160 110 120 130 140 150 160 pF1KB6 RELVIQRLSLVRSLCESEE---QRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTG : : ..:. .: . . : .: :.:.:: : . : . . : :.... . CCDS32 RGAVGEQLGKMRVFLAALEGSLDREAERVRGEAGVALRRELGSLNSYLEQLRQMEKV--- 170 180 190 200 210 220 170 180 190 200 210 220 pF1KB6 LVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVL . .. . ....: . : .. . : :... . . :.: CCDS32 -LEEVADKPQTEFLMKYCLVTSRLQKILAESPPPAR--LDIQLPIISDDFKFQVWRKMFR 230 240 250 260 270 280 230 240 250 260 270 280 pF1KB6 GSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQN . . . :.. .: .. : : .:.. . . : .:. .. :..::. ..: .... CCDS32 ALMPALEELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSE 290 300 310 320 330 340 290 300 310 320 330 340 pF1KB6 GLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFS---WVFSRYDQEFRFSHNG : : : :.: .. . .:: ... ::.: :: : . : :... . .. .: CCDS32 GEHYWEVDVGDKPRWALGVIAAEAPRRG-----RL-HAVPSQGLWLLGLREGKILEAHVE 350 360 370 380 390 350 360 370 380 390 pF1KB6 QHEPLGLL---RGPAQLGVVLDLQVQELLFYEP--ASGIV-LCAHHVSFPGPLFPVFAVA .:: .: : :...:. :.. : ::. :...: : : : .: :..: : : CCDS32 AKEPRALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVC 400 410 420 430 440 450 400 pF1KB6 DQTISIVR CCDS32 WHDKGKNAQPLLLVGPEGAEA 460 470 >>CCDS4677.1 TRIM15 gene_id:89870|Hs108|chr6 (465 aa) initn: 162 init1: 66 opt: 324 Z-score: 317.2 bits: 67.8 E(32554): 2.4e-11 Smith-Waterman score: 324; 24.9% identity (55.4% similar) in 397 aa overlap (16-393:72-454) 10 20 30 40 pF1KB6 MSAEGAEPGPGSGSGPGP-GPL----CPEHGQALSWFCGSERRPV : : ::: : :::. . .:: .. . . CCDS46 ALSQMGAQSSGKILLCPLCQEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFL 50 60 70 80 90 100 50 60 70 80 90 pF1KB6 CAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQSAAI--TKYVAD----VLPG :. : : ..: . .: . :... .. : :. . : .: : :: CCDS46 CVFCRE-GPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLT 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB6 KNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEAL . . .. .: : . :.: : : .. ..: .:. :... .. . .. . . CCDS46 QIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQV 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB6 QKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLL ..:. .. : :.:... :.. :. . :.: ... .:..: : . CCDS46 KELEEKCQQPASEL--LQDVRVNQSRCEM-KTFVSPEAISPDLVKKIRDFHRKILTLPEM 230 240 250 260 270 220 230 240 250 260 270 pF1KB6 TQLWATAVLGSL---SGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDH .... . : ::. : .: .:.: : ::.:::.. . :...:. :.: ::: CCDS46 MRMFSENLAHHLEIDSGV--ITLDPQTASRSLVLSEDRKSVRY-TRQKKSLPDSPLRFDG 280 290 300 310 320 330 280 290 300 310 320 pF1KB6 WPNALAATSFQNGLHAWMVNVQ--NSCAYKVGVASGHLPRKGSGSDCRLGHNAFS--W-V : .:. .:..: : :.:..: .. . ::::. . ::: ..: .: . : : CCDS46 LPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKG-----EMGLSAEDGVWAV 340 350 360 370 380 330 340 350 360 370 380 pF1KB6 FSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASGIVLCAHHVSFPGP . ..: . . : ::. . : . :.:: .. .. ... . . . .:: : CCDS46 IISHQQCWASTSPGTDLPLSEI--PRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGK 390 400 410 420 430 440 390 400 pF1KB6 LFPVFAVADQTISIVR .:: ::: CCDS46 VFPFFAVWKKGSCLTLKG 450 460 >>CCDS34654.1 TRIM50 gene_id:135892|Hs108|chr7 (487 aa) initn: 215 init1: 124 opt: 318 Z-score: 311.2 bits: 66.7 E(32554): 5.2e-11 Smith-Waterman score: 318; 21.4% identity (55.6% similar) in 383 aa overlap (16-391:81-454) 10 20 30 40 pF1KB6 MSAEGAEPGPGSGSGPG-PGP-LCPEHGQALSWFCGSERRPVCAA :: : : .: .: . :: :: .... .:. CCDS34 LRCPVCRQAVDGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGL 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB6 CAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMA : :: : . : . . ....... .:. .. . . .: .. ... : :. . CCDS34 C-GLLGSHQHHPVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRT-RIVNES 120 130 140 150 160 110 120 130 140 150 160 pF1KB6 SAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTG .. .. .... .. : . :. : :: . :. :. . : .... :.. .. . CCDS34 DVFSWVIRREFQELHHLVDEEKARCLEGIGGHT-RGLVASLDMQLEQAQGTRERLAQAEC 170 180 190 200 210 220 170 180 190 200 210 220 pF1KB6 LVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQESEM--LNFNEKCTRSPLLTQLWATA .. .. . : ..:.: . . :.: .. : :. . ..:. .. . .: CCDS34 VLEQFGNEDHHKFIRKFHSMASRAEMPQA--RPLEGAFSPISFKPGLHQADIKLTVWKRL 230 240 250 260 270 280 230 240 250 260 270 280 pF1KB6 VLGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSF : . : ...: :. :.:.:: .. . .. :. :::::. .::. .: CCDS34 FRKVLPAPEPLKLDPATAHPLLELSKGNTVVQCGLLAQRR-ASQPERFDYSTCVLASRGF 290 300 310 320 330 340 290 300 310 320 330 340 pF1KB6 QNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQ . : : : : : .. ...:: .: :::. . : ... :... . . . CCDS34 SCGRHYWEVVVGSKSDWRLGVIKGTASRKGKLN--RSPEHGV-WLIGLKEGRVYEAFACP 350 360 370 380 390 400 350 360 370 380 390 pF1KB6 HEPLGLLRGPAQLGVVLDLQVQELLFYE---PASGIVLCAHHVSFPGPLFPVFAVADQTI . :: . : ..:. : . :: :.. : . : . ...: : :.:.. CCDS34 RVPLPVAGHPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHER 410 420 430 440 450 460 400 pF1KB6 SIVR CCDS34 GSNSLPMVLPPPSGPGPLSPEQPTKL 470 480 402 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:29:56 2016 done: Sat Nov 5 11:29:56 2016 Total Scan time: 3.240 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]