FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6580, 403 aa 1>>>pF1KB6580 403 - 403 aa - 403 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3044+/-0.000415; mu= 12.0122+/- 0.026 mean_var=101.7526+/-20.497, 0's: 0 Z-trim(113.6): 154 B-trim: 532 in 2/53 Lambda= 0.127146 statistics sampled from 22810 (22973) to 22810 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.269), width: 16 Scan time: 8.160 The best scores are: opt bits E(85289) NP_000305 (OMIM: 153480,155600,158350,176807,18847 ( 403) 2776 520.1 3.8e-147 NP_001291646 (OMIM: 153480,155600,158350,176807,18 ( 576) 2776 520.2 5e-147 NP_001291647 (OMIM: 153480,155600,158350,176807,18 ( 206) 1415 270.3 3.1e-72 NP_001135440 (OMIM: 606791) phosphatidylinositol 3 ( 411) 657 131.4 3.9e-30 NP_570141 (OMIM: 606791) phosphatidylinositol 3,4, ( 445) 657 131.4 4.1e-30 NP_954863 (OMIM: 606791) phosphatidylinositol 3,4, ( 522) 657 131.5 4.7e-30 NP_001277153 (OMIM: 604336) putative tyrosine-prot ( 413) 616 123.9 7.2e-28 NP_954869 (OMIM: 604336) putative tyrosine-protein ( 513) 616 124.0 8.5e-28 NP_954868 (OMIM: 604336) putative tyrosine-protein ( 533) 616 124.0 8.8e-28 NP_954870 (OMIM: 604336) putative tyrosine-protein ( 551) 616 124.0 9e-28 XP_011513782 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 503 103.5 3.4e-21 XP_011513785 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 503 103.5 3.4e-21 XP_011513784 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 503 103.5 3.4e-21 XP_016868028 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 503 103.5 3.4e-21 XP_011513783 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 503 103.5 3.4e-21 NP_073585 (OMIM: 606825) tensin-3 [Homo sapiens] (1445) 503 103.5 3.4e-21 XP_011513781 (OMIM: 606825) PREDICTED: tensin-3 is (1488) 503 103.5 3.5e-21 XP_011513780 (OMIM: 606825) PREDICTED: tensin-3 is (1534) 503 103.5 3.6e-21 XP_016868026 (OMIM: 606825) PREDICTED: tensin-3 is (1548) 503 103.5 3.6e-21 XP_011513779 (OMIM: 606825) PREDICTED: tensin-3 is (1548) 503 103.5 3.6e-21 XP_016868027 (OMIM: 606825) PREDICTED: tensin-3 is (1559) 503 103.5 3.6e-21 XP_011513778 (OMIM: 606825) PREDICTED: tensin-3 is (1561) 503 103.5 3.6e-21 NP_001294952 (OMIM: 600076) tensin-1 isoform 3 [Ho (1714) 493 101.7 1.4e-20 XP_011510025 (OMIM: 600076) PREDICTED: tensin-1 is (1714) 493 101.7 1.4e-20 NP_001294951 (OMIM: 600076) tensin-1 isoform 2 [Ho (1721) 493 101.7 1.4e-20 XP_016860297 (OMIM: 600076) PREDICTED: tensin-1 is (1727) 493 101.7 1.4e-20 NP_072174 (OMIM: 600076) tensin-1 isoform 1 [Homo (1735) 493 101.7 1.4e-20 XP_016860296 (OMIM: 600076) PREDICTED: tensin-1 is (1802) 493 101.8 1.4e-20 XP_016860301 (OMIM: 600076) PREDICTED: tensin-1 is (1808) 493 101.8 1.5e-20 XP_016860300 (OMIM: 600076) PREDICTED: tensin-1 is (1808) 493 101.8 1.5e-20 XP_016860295 (OMIM: 600076) PREDICTED: tensin-1 is (1815) 493 101.8 1.5e-20 XP_016860294 (OMIM: 600076) PREDICTED: tensin-1 is (1824) 493 101.8 1.5e-20 XP_011510017 (OMIM: 600076) PREDICTED: tensin-1 is (1831) 493 101.8 1.5e-20 XP_011510015 (OMIM: 600076) PREDICTED: tensin-1 is (1839) 493 101.8 1.5e-20 XP_011510014 (OMIM: 600076) PREDICTED: tensin-1 is (1844) 493 101.8 1.5e-20 XP_016860293 (OMIM: 600076) PREDICTED: tensin-1 is (1852) 493 101.8 1.5e-20 XP_016860292 (OMIM: 600076) PREDICTED: tensin-1 is (1867) 493 101.8 1.5e-20 XP_016860291 (OMIM: 600076) PREDICTED: tensin-1 is (1880) 493 101.8 1.5e-20 XP_016860290 (OMIM: 600076) PREDICTED: tensin-1 is (1895) 493 101.8 1.5e-20 XP_016860298 (OMIM: 600076) PREDICTED: tensin-1 is (1896) 493 101.8 1.5e-20 XP_016860299 (OMIM: 600076) PREDICTED: tensin-1 is (1896) 493 101.8 1.5e-20 NP_938072 (OMIM: 607717) tensin-2 isoform 3 [Homo (1285) 456 94.9 1.2e-18 XP_011536381 (OMIM: 607717) PREDICTED: tensin-2 is (1403) 456 94.9 1.3e-18 NP_736610 (OMIM: 607717) tensin-2 isoform 2 [Homo (1409) 456 94.9 1.3e-18 XP_016874578 (OMIM: 607717) PREDICTED: tensin-2 is (1412) 456 94.9 1.3e-18 XP_016874577 (OMIM: 607717) PREDICTED: tensin-2 is (1418) 456 94.9 1.3e-18 XP_006719366 (OMIM: 607717) PREDICTED: tensin-2 is (1418) 456 94.9 1.3e-18 NP_056134 (OMIM: 607717) tensin-2 isoform 1 [Homo (1419) 456 94.9 1.3e-18 XP_006719365 (OMIM: 607717) PREDICTED: tensin-2 is (1428) 456 94.9 1.3e-18 XP_016863484 (OMIM: 602052) PREDICTED: cyclin-G-as (1131) 413 86.9 2.6e-16 >>NP_000305 (OMIM: 153480,155600,158350,176807,188470,27 (403 aa) initn: 2776 init1: 2776 opt: 2776 Z-score: 2762.8 bits: 520.1 E(85289): 3.8e-147 Smith-Waterman score: 2776; 100.0% identity (100.0% similar) in 403 aa overlap (1-403:1-403) 10 20 30 40 50 60 pF1KB6 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS 310 320 330 340 350 360 370 380 390 400 pF1KB6 SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV ::::::::::::::::::::::::::::::::::::::::::: NP_000 SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV 370 380 390 400 >>NP_001291646 (OMIM: 153480,155600,158350,176807,188470 (576 aa) initn: 2776 init1: 2776 opt: 2776 Z-score: 2760.6 bits: 520.2 E(85289): 5e-147 Smith-Waterman score: 2776; 100.0% identity (100.0% similar) in 403 aa overlap (1-403:174-576) 10 20 30 pF1KB6 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP :::::::::::::::::::::::::::::: NP_001 RAISILQKKPRHQQLLPSLSSFFFSHRLPDMTAIIKEIVSRNKRRYQEDGFDLDLTYIYP 150 160 170 180 190 200 40 50 60 70 80 90 pF1KB6 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF 210 220 230 240 250 260 100 110 120 130 140 150 pF1KB6 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE 270 280 290 300 310 320 160 170 180 190 200 210 pF1KB6 ALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGT 330 340 350 360 370 380 220 230 240 250 260 270 pF1KB6 CNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKM 390 400 410 420 430 440 280 290 300 310 320 330 pF1KB6 FHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANK 450 460 470 480 490 500 340 350 360 370 380 390 pF1KB6 DKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENE 510 520 530 540 550 560 400 pF1KB6 PFDEDQHTQITKV ::::::::::::: NP_001 PFDEDQHTQITKV 570 >>NP_001291647 (OMIM: 153480,155600,158350,176807,188470 (206 aa) initn: 1415 init1: 1415 opt: 1415 Z-score: 1417.8 bits: 270.3 E(85289): 3.1e-72 Smith-Waterman score: 1415; 100.0% identity (100.0% similar) in 206 aa overlap (198-403:1-206) 170 180 190 200 210 220 pF1KB6 IPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSS :::::::::::::::::::::::::::::: NP_001 MMFETIPMFSGGTCNPQFVVCQLKVKIYSS 10 20 30 230 240 250 260 270 280 pF1KB6 NSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETS 40 50 60 70 80 90 290 300 310 320 330 340 pF1KB6 EKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 100 110 120 130 140 150 350 360 370 380 390 400 pF1KB6 TKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV 160 170 180 190 200 >>NP_001135440 (OMIM: 606791) phosphatidylinositol 3,4,5 (411 aa) initn: 733 init1: 588 opt: 657 Z-score: 662.0 bits: 131.4 E(85289): 3.9e-30 Smith-Waterman score: 738; 37.1% identity (61.2% similar) in 361 aa overlap (1-347:86-408) 10 20 30 pF1KB6 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP . .....::.::::: .:::::::::. NP_001 VASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTE 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB6 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF ::::.::. .. ::: :..::::::.::.:::..::::.:: :: .:. ::.. . NP_001 RIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMI 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB6 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE .::: : :. . : .....:...: ....:::::.::::::.:.:: :. :: :.: NP_001 DDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEE 180 190 200 210 220 230 160 170 180 190 200 pF1KB6 ALDFYGEVRTRDK-----KGVTIPSQRRYVYYYSYLLKNHL---DYRPVALLFHKMMFET .: ..:: :: .:: ::: ::: :.. . .:: . : .:: : .. NP_001 SLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV--KHLYNWNLPPRRILFIKRFI-- 240 250 260 270 280 290 210 220 230 240 250 pF1KB6 IPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTR-----REDKFMYFEFPQPLPVCGDIKVE : . : .:. . : . : ..::.: : . ::.. . : :. :.::. NP_001 IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGP-PLYDDVKVQ 300 310 320 330 340 350 260 270 280 290 300 310 pF1KB6 FFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYL :: .. . : :: :: :: .:. :: NP_001 FFSSNLPKYYDNCPFFFWFNTSFI----------QNNRLC-------------------- 360 370 380 320 330 340 350 360 370 pF1KB6 VLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDH : .:.::. .:.:: . . :.: :.. : NP_001 ---LPRNELDNPHKQKAWKIYPPEFAVEILFGEK 390 400 410 380 390 400 pF1KB6 YRYSDTTDSDPENEPFDEDQHTQITKV >>NP_570141 (OMIM: 606791) phosphatidylinositol 3,4,5-tr (445 aa) initn: 733 init1: 588 opt: 657 Z-score: 661.5 bits: 131.4 E(85289): 4.1e-30 Smith-Waterman score: 738; 37.1% identity (61.2% similar) in 361 aa overlap (1-347:120-442) 10 20 30 pF1KB6 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP . .....::.::::: .:::::::::. NP_570 VFVEGWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTE 90 100 110 120 130 140 40 50 60 70 80 90 pF1KB6 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF ::::.::. .. ::: :..::::::.::.:::..::::.:: :: .:. ::.. . NP_570 RIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMI 150 160 170 180 190 200 100 110 120 130 140 150 pF1KB6 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE .::: : :. . : .....:...: ....:::::.::::::.:.:: :. :: :.: NP_570 DDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEE 210 220 230 240 250 260 160 170 180 190 200 pF1KB6 ALDFYGEVRTRDK-----KGVTIPSQRRYVYYYSYLLKNHL---DYRPVALLFHKMMFET .: ..:: :: .:: ::: ::: :.. . .:: . : .:: : .. NP_570 SLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV--KHLYNWNLPPRRILFIKRFI-- 270 280 290 300 310 320 210 220 230 240 250 pF1KB6 IPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTR-----REDKFMYFEFPQPLPVCGDIKVE : . : .:. . : . : ..::.: : . ::.. . : :. :.::. NP_570 IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGP-PLYDDVKVQ 330 340 350 360 370 380 260 270 280 290 300 310 pF1KB6 FFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYL :: .. . : :: :: :: .:. :: NP_570 FFSSNLPKYYDNCPFFFWFNTSFI----------QNNRLC-------------------- 390 400 410 320 330 340 350 360 370 pF1KB6 VLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDH : .:.::. .:.:: . . :.: :.. : NP_570 ---LPRNELDNPHKQKAWKIYPPEFAVEILFGEK 420 430 440 380 390 400 pF1KB6 YRYSDTTDSDPENEPFDEDQHTQITKV >>NP_954863 (OMIM: 606791) phosphatidylinositol 3,4,5-tr (522 aa) initn: 733 init1: 588 opt: 657 Z-score: 660.5 bits: 131.5 E(85289): 4.7e-30 Smith-Waterman score: 738; 37.1% identity (61.2% similar) in 361 aa overlap (1-347:197-519) 10 20 30 pF1KB6 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP . .....::.::::: .:::::::::. NP_954 RNIPRWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTE 170 180 190 200 210 220 40 50 60 70 80 90 pF1KB6 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF ::::.::. .. ::: :..::::::.::.:::..::::.:: :: .:. ::.. . NP_954 RIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMI 230 240 250 260 270 280 100 110 120 130 140 150 pF1KB6 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE .::: : :. . : .....:...: ....:::::.::::::.:.:: :. :: :.: NP_954 DDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEE 290 300 310 320 330 340 160 170 180 190 200 pF1KB6 ALDFYGEVRTRDK-----KGVTIPSQRRYVYYYSYLLKNHL---DYRPVALLFHKMMFET .: ..:: :: .:: ::: ::: :.. . .:: . : .:: : .. NP_954 SLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV--KHLYNWNLPPRRILFIKRFI-- 350 360 370 380 390 400 210 220 230 240 250 pF1KB6 IPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTR-----REDKFMYFEFPQPLPVCGDIKVE : . : .:. . : . : ..::.: : . ::.. . : :. :.::. NP_954 IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGP-PLYDDVKVQ 410 420 430 440 450 460 260 270 280 290 300 310 pF1KB6 FFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYL :: .. . : :: :: :: .:. :: NP_954 FFSSNLPKYYDNCPFFFWFNTSFI----------QNNRLC-------------------- 470 480 490 320 330 340 350 360 370 pF1KB6 VLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDH : .:.::. .:.:: . . :.: :.. : NP_954 ---LPRNELDNPHKQKAWKIYPPEFAVEILFGEK 500 510 520 380 390 400 pF1KB6 YRYSDTTDSDPENEPFDEDQHTQITKV >>NP_001277153 (OMIM: 604336) putative tyrosine-protein (413 aa) initn: 747 init1: 553 opt: 616 Z-score: 621.3 bits: 123.9 E(85289): 7.2e-28 Smith-Waterman score: 685; 34.9% identity (61.8% similar) in 361 aa overlap (1-347:77-399) 10 20 30 pF1KB6 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP . .:.. ::.::::: .:::::::::. NP_001 RNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTE 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB6 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF ::::.::. .. ::: : .::::::.::.:::..::::.:: :: .:. ::.. . NP_001 RIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMI 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB6 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE .::: : :. . : .....:...: ....:::::.: :::.:.::.:. :.: NP_001 DDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKE 170 180 190 200 210 220 160 170 180 190 200 pF1KB6 ALDFYGEVRTRDK------KGVTIPSQRRYVYYYS---YLLKNHLDYRPVALLFHKMMFE .: ..:: :: :: .:: :::.::: :.. .: . .: : . .. : ... NP_001 SLYYFGERRT-DKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIY- 230 240 250 260 270 280 210 220 230 240 250 pF1KB6 TIPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTRREDKF----MYFEFPQPLPVCGDIKVE .:: . . . .. . . : ..:. : : :.. . .. . ::. :.::. NP_001 SIPRY---VRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQ 290 300 310 320 330 340 260 270 280 290 300 310 pF1KB6 FFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYL ::... . :.::..: :: .:.. : NP_001 FFYSNLPTYYDNCSFYFWLHTSFI-----------------------------ENNRLY- 350 360 370 320 330 340 350 360 370 pF1KB6 VLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDH : ::.::. .:.:: : . .: :.. : NP_001 ---LPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD 380 390 400 410 380 390 400 pF1KB6 YRYSDTTDSDPENEPFDEDQHTQITKV >>NP_954869 (OMIM: 604336) putative tyrosine-protein pho (513 aa) initn: 747 init1: 553 opt: 616 Z-score: 620.0 bits: 124.0 E(85289): 8.5e-28 Smith-Waterman score: 685; 34.9% identity (61.8% similar) in 361 aa overlap (1-347:177-499) 10 20 30 pF1KB6 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP . .:.. ::.::::: .:::::::::. NP_954 RNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTE 150 160 170 180 190 200 40 50 60 70 80 90 pF1KB6 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF ::::.::. .. ::: : .::::::.::.:::..::::.:: :: .:. ::.. . NP_954 RIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMI 210 220 230 240 250 260 100 110 120 130 140 150 pF1KB6 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE .::: : :. . : .....:...: ....:::::.: :::.:.::.:. :.: NP_954 DDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKE 270 280 290 300 310 320 160 170 180 190 200 pF1KB6 ALDFYGEVRTRDK------KGVTIPSQRRYVYYYS---YLLKNHLDYRPVALLFHKMMFE .: ..:: :: :: .:: :::.::: :.. .: . .: : . .. : ... NP_954 SLYYFGERRT-DKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIY- 330 340 350 360 370 380 210 220 230 240 250 pF1KB6 TIPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTRREDKF----MYFEFPQPLPVCGDIKVE .:: . . . .. . . : ..:. : : :.. . .. . ::. :.::. NP_954 SIPRY---VRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQ 390 400 410 420 430 440 260 270 280 290 300 310 pF1KB6 FFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYL ::... . :.::..: :: .:.. : NP_954 FFYSNLPTYYDNCSFYFWLHTSFI-----------------------------ENNRLY- 450 460 470 320 330 340 350 360 370 pF1KB6 VLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDH : ::.::. .:.:: : . .: :.. : NP_954 ---LPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD 480 490 500 510 380 390 400 pF1KB6 YRYSDTTDSDPENEPFDEDQHTQITKV >>NP_954868 (OMIM: 604336) putative tyrosine-protein pho (533 aa) initn: 747 init1: 553 opt: 616 Z-score: 619.8 bits: 124.0 E(85289): 8.8e-28 Smith-Waterman score: 685; 34.9% identity (61.8% similar) in 361 aa overlap (1-347:197-519) 10 20 30 pF1KB6 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP . .:.. ::.::::: .:::::::::. NP_954 RNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTE 170 180 190 200 210 220 40 50 60 70 80 90 pF1KB6 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF ::::.::. .. ::: : .::::::.::.:::..::::.:: :: .:. ::.. . NP_954 RIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMI 230 240 250 260 270 280 100 110 120 130 140 150 pF1KB6 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE .::: : :. . : .....:...: ....:::::.: :::.:.::.:. :.: NP_954 DDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKE 290 300 310 320 330 340 160 170 180 190 200 pF1KB6 ALDFYGEVRTRDK------KGVTIPSQRRYVYYYS---YLLKNHLDYRPVALLFHKMMFE .: ..:: :: :: .:: :::.::: :.. .: . .: : . .. : ... NP_954 SLYYFGERRT-DKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIY- 350 360 370 380 390 400 210 220 230 240 250 pF1KB6 TIPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTRREDKF----MYFEFPQPLPVCGDIKVE .:: . . . .. . . : ..:. : : :.. . .. . ::. :.::. NP_954 SIPRY---VRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQ 410 420 430 440 450 460 260 270 280 290 300 310 pF1KB6 FFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYL ::... . :.::..: :: .:.. : NP_954 FFYSNLPTYYDNCSFYFWLHTSFI-----------------------------ENNRLY- 470 480 490 320 330 340 350 360 370 pF1KB6 VLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDH : ::.::. .:.:: : . .: :.. : NP_954 ---LPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD 500 510 520 530 380 390 400 pF1KB6 YRYSDTTDSDPENEPFDEDQHTQITKV >>NP_954870 (OMIM: 604336) putative tyrosine-protein pho (551 aa) initn: 747 init1: 553 opt: 616 Z-score: 619.5 bits: 124.0 E(85289): 9e-28 Smith-Waterman score: 685; 34.9% identity (61.8% similar) in 361 aa overlap (1-347:215-537) 10 20 30 pF1KB6 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP . .:.. ::.::::: .:::::::::. NP_954 RNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTE 190 200 210 220 230 240 40 50 60 70 80 90 pF1KB6 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF ::::.::. .. ::: : .::::::.::.:::..::::.:: :: .:. ::.. . NP_954 RIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMI 250 260 270 280 290 300 100 110 120 130 140 150 pF1KB6 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE .::: : :. . : .....:...: ....:::::.: :::.:.::.:. :.: NP_954 DDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKE 310 320 330 340 350 360 160 170 180 190 200 pF1KB6 ALDFYGEVRTRDK------KGVTIPSQRRYVYYYS---YLLKNHLDYRPVALLFHKMMFE .: ..:: :: :: .:: :::.::: :.. .: . .: : . .. : ... NP_954 SLYYFGERRT-DKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIY- 370 380 390 400 410 420 210 220 230 240 250 pF1KB6 TIPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTRREDKF----MYFEFPQPLPVCGDIKVE .:: . . . .. . . : ..:. : : :.. . .. . ::. :.::. NP_954 SIPRY---VRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQ 430 440 450 460 470 260 270 280 290 300 310 pF1KB6 FFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYL ::... . :.::..: :: .:.. : NP_954 FFYSNLPTYYDNCSFYFWLHTSFI-----------------------------ENNRLY- 480 490 500 320 330 340 350 360 370 pF1KB6 VLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDH : ::.::. .:.:: : . .: :.. : NP_954 ---LPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD 510 520 530 540 550 380 390 400 pF1KB6 YRYSDTTDSDPENEPFDEDQHTQITKV 403 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:03:21 2016 done: Sat Nov 5 04:03:22 2016 Total Scan time: 8.160 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]