FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6582, 404 aa 1>>>pF1KB6582 404 - 404 aa - 404 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2171+/-0.000335; mu= 9.1163+/- 0.021 mean_var=122.1575+/-24.585, 0's: 0 Z-trim(118.5): 52 B-trim: 0 in 0/53 Lambda= 0.116042 statistics sampled from 31514 (31566) to 31514 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.37), width: 16 Scan time: 9.490 The best scores are: opt bits E(85289) NP_004148 (OMIM: 176910) cAMP-dependent protein ki ( 404) 2662 456.5 5.4e-128 XP_016862304 (OMIM: 176910) PREDICTED: cAMP-depend ( 404) 2662 456.5 5.4e-128 XP_011532244 (OMIM: 176910) PREDICTED: cAMP-depend ( 404) 2662 456.5 5.4e-128 NP_001308911 (OMIM: 176910) cAMP-dependent protein ( 404) 2662 456.5 5.4e-128 XP_016862305 (OMIM: 176910) PREDICTED: cAMP-depend ( 330) 2054 354.6 2e-97 XP_005265372 (OMIM: 176910) PREDICTED: cAMP-depend ( 330) 2054 354.6 2e-97 XP_011532245 (OMIM: 176910) PREDICTED: cAMP-depend ( 349) 2054 354.6 2.1e-97 NP_001308912 (OMIM: 176910) cAMP-dependent protein ( 382) 1921 332.4 1.1e-90 NP_001308918 (OMIM: 176910) cAMP-dependent protein ( 376) 1688 293.4 6.2e-79 NP_002727 (OMIM: 176912) cAMP-dependent protein ki ( 418) 1601 278.8 1.7e-74 XP_011514700 (OMIM: 176912) PREDICTED: cAMP-depend ( 390) 1281 225.3 2.1e-58 NP_002725 (OMIM: 101800,160980,188550,188830,25596 ( 381) 777 140.9 5.1e-33 XP_011523287 (OMIM: 101800,160980,188550,188830,25 ( 381) 777 140.9 5.1e-33 XP_011523285 (OMIM: 101800,160980,188550,188830,25 ( 381) 777 140.9 5.1e-33 NP_997637 (OMIM: 101800,160980,188550,188830,25596 ( 381) 777 140.9 5.1e-33 NP_001263218 (OMIM: 101800,160980,188550,188830,25 ( 381) 777 140.9 5.1e-33 NP_001265362 (OMIM: 101800,160980,188550,188830,25 ( 381) 777 140.9 5.1e-33 XP_011523286 (OMIM: 101800,160980,188550,188830,25 ( 381) 777 140.9 5.1e-33 NP_997636 (OMIM: 101800,160980,188550,188830,25596 ( 381) 777 140.9 5.1e-33 XP_011513748 (OMIM: 176911) PREDICTED: cAMP-depend ( 326) 774 140.3 6.4e-33 NP_001158234 (OMIM: 176911) cAMP-dependent protein ( 381) 771 139.9 1e-32 NP_001158232 (OMIM: 176911) cAMP-dependent protein ( 381) 771 139.9 1e-32 NP_001158231 (OMIM: 176911) cAMP-dependent protein ( 381) 771 139.9 1e-32 NP_001158230 (OMIM: 176911) cAMP-dependent protein ( 381) 771 139.9 1e-32 NP_002726 (OMIM: 176911) cAMP-dependent protein ki ( 381) 771 139.9 1e-32 NP_001158233 (OMIM: 176911) cAMP-dependent protein ( 381) 771 139.9 1e-32 XP_016867923 (OMIM: 176911) PREDICTED: cAMP-depend ( 229) 668 122.5 1e-27 NP_001263219 (OMIM: 101800,160980,188550,188830,25 ( 337) 589 109.4 1.4e-23 XP_016867922 (OMIM: 176911) PREDICTED: cAMP-depend ( 251) 578 107.5 3.9e-23 XP_016863907 (OMIM: 601591) PREDICTED: cGMP-depend ( 462) 468 89.2 2.3e-17 NP_001269414 (OMIM: 601591) cGMP-dependent protein ( 733) 468 89.3 3.3e-17 XP_016863906 (OMIM: 601591) PREDICTED: cGMP-depend ( 745) 468 89.3 3.4e-17 NP_006250 (OMIM: 601591) cGMP-dependent protein ki ( 762) 468 89.3 3.4e-17 XP_005263183 (OMIM: 601591) PREDICTED: cGMP-depend ( 762) 468 89.3 3.4e-17 XP_016863903 (OMIM: 601591) PREDICTED: cGMP-depend ( 774) 468 89.3 3.5e-17 XP_016863902 (OMIM: 601591) PREDICTED: cGMP-depend ( 774) 468 89.3 3.5e-17 XP_016863905 (OMIM: 601591) PREDICTED: cGMP-depend ( 774) 468 89.3 3.5e-17 XP_016863904 (OMIM: 601591) PREDICTED: cGMP-depend ( 774) 468 89.3 3.5e-17 XP_011538254 (OMIM: 176894,615436) PREDICTED: cGMP ( 406) 456 87.1 8.2e-17 NP_006249 (OMIM: 176894,615436) cGMP-dependent pro ( 686) 456 87.3 1.3e-16 XP_016871901 (OMIM: 176894,615436) PREDICTED: cGMP ( 591) 445 85.4 4e-16 NP_001091982 (OMIM: 176894,615436) cGMP-dependent ( 671) 445 85.4 4.5e-16 XP_016871902 (OMIM: 176894,615436) PREDICTED: cGMP ( 585) 433 83.4 1.6e-15 >>NP_004148 (OMIM: 176910) cAMP-dependent protein kinase (404 aa) initn: 2662 init1: 2662 opt: 2662 Z-score: 2418.8 bits: 456.5 E(85289): 5.4e-128 Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL 310 320 330 340 350 360 370 380 390 400 pF1KB6 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ :::::::::::::::::::::::::::::::::::::::::::: NP_004 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ 370 380 390 400 >>XP_016862304 (OMIM: 176910) PREDICTED: cAMP-dependent (404 aa) initn: 2662 init1: 2662 opt: 2662 Z-score: 2418.8 bits: 456.5 E(85289): 5.4e-128 Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL 310 320 330 340 350 360 370 380 390 400 pF1KB6 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ :::::::::::::::::::::::::::::::::::::::::::: XP_016 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ 370 380 390 400 >>XP_011532244 (OMIM: 176910) PREDICTED: cAMP-dependent (404 aa) initn: 2662 init1: 2662 opt: 2662 Z-score: 2418.8 bits: 456.5 E(85289): 5.4e-128 Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL 310 320 330 340 350 360 370 380 390 400 pF1KB6 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ :::::::::::::::::::::::::::::::::::::::::::: XP_011 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ 370 380 390 400 >>NP_001308911 (OMIM: 176910) cAMP-dependent protein kin (404 aa) initn: 2662 init1: 2662 opt: 2662 Z-score: 2418.8 bits: 456.5 E(85289): 5.4e-128 Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL 310 320 330 340 350 360 370 380 390 400 pF1KB6 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ :::::::::::::::::::::::::::::::::::::::::::: NP_001 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ 370 380 390 400 >>XP_016862305 (OMIM: 176910) PREDICTED: cAMP-dependent (330 aa) initn: 2054 init1: 2054 opt: 2054 Z-score: 1870.0 bits: 354.6 E(85289): 2e-97 Smith-Waterman score: 2054; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313) 10 20 30 40 50 60 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL ::::::::::::: XP_016 IESGEVSILIRSRLWMYKHSRGFWGPAWTS 310 320 330 >>XP_005265372 (OMIM: 176910) PREDICTED: cAMP-dependent (330 aa) initn: 2054 init1: 2054 opt: 2054 Z-score: 1870.0 bits: 354.6 E(85289): 2e-97 Smith-Waterman score: 2054; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313) 10 20 30 40 50 60 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL ::::::::::::: XP_005 IESGEVSILIRSRLWMYKHSRGFWGPAWTS 310 320 330 >>XP_011532245 (OMIM: 176910) PREDICTED: cAMP-dependent (349 aa) initn: 2054 init1: 2054 opt: 2054 Z-score: 1869.7 bits: 354.6 E(85289): 2.1e-97 Smith-Waterman score: 2054; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313) 10 20 30 40 50 60 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL ::::::::::::: XP_011 IESGEVSILIRSRQALTYSAIFYCCLGLGSLCDQPEMDEWMLSANISEY 310 320 330 340 >>NP_001308912 (OMIM: 176910) cAMP-dependent protein kin (382 aa) initn: 1921 init1: 1921 opt: 1921 Z-score: 1748.7 bits: 332.4 E(85289): 1.1e-90 Smith-Waterman score: 2475; 94.6% identity (94.6% similar) in 404 aa overlap (1-404:1-382) 10 20 30 40 50 60 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQ--------- 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------------TKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL 300 310 320 330 370 380 390 400 pF1KB6 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ :::::::::::::::::::::::::::::::::::::::::::: NP_001 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ 340 350 360 370 380 >>NP_001308918 (OMIM: 176910) cAMP-dependent protein kin (376 aa) initn: 1672 init1: 1672 opt: 1688 Z-score: 1538.0 bits: 293.4 E(85289): 6.2e-79 Smith-Waterman score: 2401; 93.1% identity (93.1% similar) in 404 aa overlap (1-404:1-376) 10 20 30 40 50 60 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPR--- 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 PKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE ::::::::::::::::::::::::::::::::::: NP_001 -------------------------EQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIE 120 130 140 150 190 200 210 220 230 240 pF1KB6 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRI 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYI 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCL 280 290 300 310 320 330 370 380 390 400 pF1KB6 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ :::::::::::::::::::::::::::::::::::::::::::: NP_001 VMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ 340 350 360 370 >>NP_002727 (OMIM: 176912) cAMP-dependent protein kinase (418 aa) initn: 1767 init1: 1187 opt: 1601 Z-score: 1458.6 bits: 278.8 E(85289): 1.7e-74 Smith-Waterman score: 1759; 66.7% identity (84.0% similar) in 412 aa overlap (4-399:3-413) 10 20 30 40 50 pF1KB6 MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLR---EARAPASVLPAATPRQ :.:: ::::::::.::::::.:: ::.:::...::::. : .. : . NP_002 MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGTARFGHEGRTWG 10 20 30 40 50 60 70 80 90 100 pF1KB6 SLGHPP----PEPGPDRVADA-KGDSESEEDED--------LEVPVPSRFNRRVSVCAET .:: : : . . . ..:::. :.:. ...:: .::.::.:::::. NP_002 DLGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 YNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADE :::::::.:.. :.::::::.:: :::::::::::::::: ::.:::::::::..:: : NP_002 YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGE 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 HVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVAT :::::::::::::::.:::.:: : :. : ::.::::::::::::::::::::::.:: NP_002 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 SEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKD : :.:::::::::::::::::::::::.::::::.:.::::: :::.:.::::: :.:.: NP_002 SPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYND 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 GERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTN ::.::.::..::::.:.:::::.: .. . ::. . : :::::: .:::::::::::: NP_002 GEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEE-NGAVEIARCSRGQYFGELALVTN 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB6 KPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ :::::::.:.: ::::.::::::::::::::.::::::. :::::: .::...:. NP_002 KPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA 360 370 380 390 400 410 404 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:21:22 2016 done: Fri Nov 4 23:21:23 2016 Total Scan time: 9.490 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]