FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6583, 377 aa 1>>>pF1KB6583 377 - 377 aa - 377 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2215+/-0.000304; mu= 0.2341+/- 0.019 mean_var=196.6172+/-38.755, 0's: 0 Z-trim(123.5): 6 B-trim: 75 in 1/60 Lambda= 0.091467 statistics sampled from 43499 (43506) to 43499 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.51), width: 16 Scan time: 9.620 The best scores are: opt bits E(85289) NP_004556 (OMIM: 601791,614887) peroxisomal membra ( 377) 2459 336.2 7.8e-92 XP_011539879 (OMIM: 601791,614887) PREDICTED: pero ( 391) 2384 326.3 7.6e-89 XP_011539880 (OMIM: 601791,614887) PREDICTED: pero ( 358) 2278 312.3 1.2e-84 XP_005263527 (OMIM: 601791,614887) PREDICTED: pero ( 313) 2055 282.8 7.4e-76 XP_011539882 (OMIM: 601791,614887) PREDICTED: pero ( 334) 1812 250.8 3.5e-66 XP_011539881 (OMIM: 601791,614887) PREDICTED: pero ( 348) 1812 250.8 3.6e-66 >>NP_004556 (OMIM: 601791,614887) peroxisomal membrane p (377 aa) initn: 2459 init1: 2459 opt: 2459 Z-score: 1769.7 bits: 336.2 E(85289): 7.8e-92 Smith-Waterman score: 2459; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB6 MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKGLTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKGLTD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRWRDYGALAIIMAGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRWRDYGALAIIMAGIA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQLQTTLASVQELLIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQLQTTLASVQELLIQQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 WQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGSTVTYHLLGPQEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 WQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGSTVTYHLLGPQEEGE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 GVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQ 310 320 330 340 350 360 370 pF1KB6 VEKLRRPEGASNESERD ::::::::::::::::: NP_004 VEKLRRPEGASNESERD 370 >>XP_011539879 (OMIM: 601791,614887) PREDICTED: peroxiso (391 aa) initn: 2384 init1: 2384 opt: 2384 Z-score: 1716.0 bits: 326.3 E(85289): 7.6e-89 Smith-Waterman score: 2384; 100.0% identity (100.0% similar) in 365 aa overlap (13-377:27-391) 10 20 30 40 pF1KB6 MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPL :::::::::::::::::::::::::::::::::: XP_011 MDTRRWGSWGHLRVCSPQDSFSFWATPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 ATRRAFLKKKGLTDEEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATRRAFLKKKGLTDEEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRW 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 RDYGALAIIMAGIAFGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDYGALAIIMAGIAFGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQL 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 QTTLASVQELLIQQQQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTTLASVQELLIQQQQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 RQFPPSPSAPKIPSWQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQFPPSPSAPKIPSWQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB6 TVTYHLLGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVTYHLLGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQ 310 320 330 340 350 360 350 360 370 pF1KB6 REDRRGGDGQINEQVEKLRRPEGASNESERD ::::::::::::::::::::::::::::::: XP_011 REDRRGGDGQINEQVEKLRRPEGASNESERD 370 380 390 >>XP_011539880 (OMIM: 601791,614887) PREDICTED: peroxiso (358 aa) initn: 2278 init1: 2278 opt: 2278 Z-score: 1641.0 bits: 312.3 E(85289): 1.2e-84 Smith-Waterman score: 2278; 99.7% identity (100.0% similar) in 350 aa overlap (28-377:9-358) 10 20 30 40 50 60 pF1KB6 MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKGLTD .:::::::::::::::::::::::::::::::: XP_011 MLNKLICLMIATAVKFLQNSRVRQSPLATRRAFLKKKGLTD 10 20 30 40 70 80 90 100 110 120 pF1KB6 EEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRWRDYGALAIIMAGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRWRDYGALAIIMAGIA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 FGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQLQTTLASVQELLIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQLQTTLASVQELLIQQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 QQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPS 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 WQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGSTVTYHLLGPQEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGSTVTYHLLGPQEEGE 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB6 GVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQ 290 300 310 320 330 340 370 pF1KB6 VEKLRRPEGASNESERD ::::::::::::::::: XP_011 VEKLRRPEGASNESERD 350 >>XP_005263527 (OMIM: 601791,614887) PREDICTED: peroxiso (313 aa) initn: 2055 init1: 2055 opt: 2055 Z-score: 1482.8 bits: 282.8 E(85289): 7.4e-76 Smith-Waterman score: 2055; 100.0% identity (100.0% similar) in 313 aa overlap (65-377:1-313) 40 50 60 70 80 90 pF1KB6 FLQNSRVRQSPLATRRAFLKKKGLTDEEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHL :::::::::::::::::::::::::::::: XP_005 MAFQQSGTAADEPSSLGPATQVVPVQPPHL 10 20 30 100 110 120 130 140 150 pF1KB6 ISQPYSPAGSRWRDYGALAIIMAGIAFGFHQLYKKYLLPLILGGREDRKQLERMEAGLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISQPYSPAGSRWRDYGALAIIMAGIAFGFHQLYKKYLLPLILGGREDRKQLERMEAGLSE 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 LSGSVAQTVTQLQTTLASVQELLIQQQQKIQELAHELAAAKATTSTNWILESQNINELKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSGSVAQTVTQLQTTLASVQELLIQQQQKIQELAHELAAAKATTSTNWILESQNINELKS 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 EINSLKGLLLNRRQFPPSPSAPKIPSWQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EINSLKGLLLNRRQFPPSPSAPKIPSWQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 SPGKEGHSPEGSTVTYHLLGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPGKEGHSPEGSTVTYHLLGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDV 220 230 240 250 260 270 340 350 360 370 pF1KB6 SHVDEEDCLGVQREDRRGGDGQINEQVEKLRRPEGASNESERD ::::::::::::::::::::::::::::::::::::::::::: XP_005 SHVDEEDCLGVQREDRRGGDGQINEQVEKLRRPEGASNESERD 280 290 300 310 >>XP_011539882 (OMIM: 601791,614887) PREDICTED: peroxiso (334 aa) initn: 2159 init1: 1812 opt: 1812 Z-score: 1309.1 bits: 250.8 E(85289): 3.5e-66 Smith-Waterman score: 2077; 88.6% identity (88.6% similar) in 377 aa overlap (1-377:1-334) 10 20 30 40 50 60 pF1KB6 MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKGLTD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKG--- 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 EEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRWRDYGALAIIMAGIA :::::::::::::::::::: XP_011 ----------------------------------------PAGSRWRDYGALAIIMAGIA 60 70 130 140 150 160 170 180 pF1KB6 FGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQLQTTLASVQELLIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQLQTTLASVQELLIQQ 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB6 QQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPS 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB6 WQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGSTVTYHLLGPQEEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGSTVTYHLLGPQEEGE 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB6 GVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQ 260 270 280 290 300 310 370 pF1KB6 VEKLRRPEGASNESERD ::::::::::::::::: XP_011 VEKLRRPEGASNESERD 320 330 >>XP_011539881 (OMIM: 601791,614887) PREDICTED: peroxiso (348 aa) initn: 2084 init1: 1812 opt: 1812 Z-score: 1308.8 bits: 250.8 E(85289): 3.6e-66 Smith-Waterman score: 2002; 88.2% identity (88.2% similar) in 365 aa overlap (13-377:27-348) 10 20 30 40 pF1KB6 MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPL :::::::::::::::::::::::::::::::::: XP_011 MDTRRWGSWGHLRVCSPQDSFSFWATPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 ATRRAFLKKKGLTDEEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRW ::::::::::: :::::: XP_011 ATRRAFLKKKG-------------------------------------------PAGSRW 70 110 120 130 140 150 160 pF1KB6 RDYGALAIIMAGIAFGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDYGALAIIMAGIAFGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQL 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB6 QTTLASVQELLIQQQQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTTLASVQELLIQQQQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNR 140 150 160 170 180 190 230 240 250 260 270 280 pF1KB6 RQFPPSPSAPKIPSWQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQFPPSPSAPKIPSWQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGS 200 210 220 230 240 250 290 300 310 320 330 340 pF1KB6 TVTYHLLGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVTYHLLGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQ 260 270 280 290 300 310 350 360 370 pF1KB6 REDRRGGDGQINEQVEKLRRPEGASNESERD ::::::::::::::::::::::::::::::: XP_011 REDRRGGDGQINEQVEKLRRPEGASNESERD 320 330 340 377 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:30:34 2016 done: Sat Nov 5 11:30:36 2016 Total Scan time: 9.620 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]