FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6588, 406 aa 1>>>pF1KB6588 406 - 406 aa - 406 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6568+/-0.000929; mu= 10.2694+/- 0.056 mean_var=95.7788+/-18.924, 0's: 0 Z-trim(107.1): 56 B-trim: 0 in 0/53 Lambda= 0.131051 statistics sampled from 9326 (9382) to 9326 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.288), width: 16 Scan time: 2.760 The best scores are: opt bits E(32554) CCDS11645.1 PSMC5 gene_id:5705|Hs108|chr17 ( 406) 2613 504.5 7.3e-143 CCDS56043.1 PSMC5 gene_id:5705|Hs108|chr17 ( 398) 2557 493.9 1.1e-139 CCDS5731.1 PSMC2 gene_id:5701|Hs108|chr7 ( 433) 1168 231.3 1.3e-60 CCDS32139.1 PSMC1 gene_id:5700|Hs108|chr14 ( 440) 1161 230.0 3.4e-60 CCDS81837.1 PSMC1 gene_id:5700|Hs108|chr14 ( 367) 1156 229.0 5.6e-60 CCDS9710.2 PSMC6 gene_id:5706|Hs108|chr14 ( 403) 1141 226.2 4.4e-59 CCDS7935.1 PSMC3 gene_id:5702|Hs108|chr11 ( 439) 1055 209.9 3.7e-54 CCDS12547.1 PSMC4 gene_id:5704|Hs108|chr19 ( 418) 1052 209.4 5.2e-54 CCDS46076.1 PSMC4 gene_id:5704|Hs108|chr19 ( 387) 1051 209.2 5.6e-54 CCDS11859.1 AFG3L2 gene_id:10939|Hs108|chr18 ( 797) 713 145.4 1.8e-34 CCDS6573.1 VCP gene_id:7415|Hs108|chr9 ( 806) 689 140.9 4.2e-33 CCDS10977.1 SPG7 gene_id:6687|Hs108|chr16 ( 795) 634 130.4 5.7e-30 CCDS3730.1 SPATA5 gene_id:166378|Hs108|chr4 ( 893) 631 129.9 9.3e-30 CCDS4877.1 PEX6 gene_id:5190|Hs108|chr6 ( 980) 627 129.2 1.7e-29 CCDS58072.1 YME1L1 gene_id:10730|Hs108|chr10 ( 683) 619 127.6 3.5e-29 CCDS7151.1 YME1L1 gene_id:10730|Hs108|chr10 ( 716) 619 127.6 3.7e-29 CCDS7152.1 YME1L1 gene_id:10730|Hs108|chr10 ( 773) 619 127.6 3.9e-29 CCDS6343.1 ATAD2 gene_id:29028|Hs108|chr8 (1390) 610 126.0 2.1e-28 CCDS64710.1 PEX1 gene_id:5189|Hs108|chr7 (1226) 597 123.5 1.1e-27 CCDS5627.1 PEX1 gene_id:5189|Hs108|chr7 (1283) 597 123.5 1.1e-27 CCDS46227.1 ATAD2B gene_id:54454|Hs108|chr2 (1458) 581 120.5 1e-26 CCDS58062.1 NVL gene_id:4931|Hs108|chr1 ( 667) 563 117.0 5.3e-26 CCDS5217.1 KATNA1 gene_id:11104|Hs108|chr6 ( 491) 557 115.8 9e-26 CCDS31956.1 KATNAL1 gene_id:84056|Hs108|chr13 ( 490) 556 115.6 1e-25 CCDS1542.1 NVL gene_id:4931|Hs108|chr1 ( 750) 555 115.5 1.7e-25 CCDS58063.1 NVL gene_id:4931|Hs108|chr1 ( 765) 555 115.5 1.7e-25 CCDS1541.1 NVL gene_id:4931|Hs108|chr1 ( 856) 555 115.5 1.9e-25 CCDS32828.1 KATNAL2 gene_id:83473|Hs108|chr18 ( 466) 509 106.7 4.6e-23 CCDS7386.1 ATAD1 gene_id:84896|Hs108|chr10 ( 361) 506 106.1 5.5e-23 CCDS1779.1 SPAST gene_id:6683|Hs108|chr2 ( 584) 503 105.6 1.2e-22 CCDS1778.1 SPAST gene_id:6683|Hs108|chr2 ( 616) 503 105.6 1.3e-22 CCDS45517.1 VPS4A gene_id:27183|Hs108|chr16 ( 437) 498 104.6 1.8e-22 CCDS11983.1 VPS4B gene_id:9525|Hs108|chr18 ( 444) 488 102.7 6.9e-22 CCDS5510.1 FIGNL1 gene_id:63979|Hs108|chr7 ( 674) 489 103.0 8.8e-22 CCDS42354.1 NSF gene_id:4905|Hs108|chr17 ( 744) 472 99.8 8.9e-21 CCDS81877.1 SPATA5L1 gene_id:79029|Hs108|chr15 ( 620) 418 89.6 8.9e-18 CCDS10123.1 SPATA5L1 gene_id:79029|Hs108|chr15 ( 753) 418 89.6 1.1e-17 CCDS2221.2 FIGN gene_id:55137|Hs108|chr2 ( 759) 384 83.2 9.2e-16 CCDS56456.1 KATNA1 gene_id:11104|Hs108|chr6 ( 311) 347 76.0 5.4e-14 CCDS10978.1 SPG7 gene_id:6687|Hs108|chr16 ( 489) 349 76.5 6.2e-14 >>CCDS11645.1 PSMC5 gene_id:5705|Hs108|chr17 (406 aa) initn: 2613 init1: 2613 opt: 2613 Z-score: 2678.3 bits: 504.5 E(32554): 7.3e-143 Smith-Waterman score: 2613; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406) 10 20 30 40 50 60 pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK 310 320 330 340 350 360 370 380 390 400 pF1KB6 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK :::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK 370 380 390 400 >>CCDS56043.1 PSMC5 gene_id:5705|Hs108|chr17 (398 aa) initn: 2557 init1: 2557 opt: 2557 Z-score: 2621.2 bits: 493.9 E(32554): 1.1e-139 Smith-Waterman score: 2557; 100.0% identity (100.0% similar) in 398 aa overlap (9-406:1-398) 10 20 30 40 50 60 pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK 300 310 320 330 340 350 370 380 390 400 pF1KB6 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK :::::::::::::::::::::::::::::::::::::::::::::: CCDS56 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK 360 370 380 390 >>CCDS5731.1 PSMC2 gene_id:5701|Hs108|chr7 (433 aa) initn: 1149 init1: 1149 opt: 1168 Z-score: 1201.4 bits: 231.3 E(32554): 1.3e-60 Smith-Waterman score: 1168; 50.8% identity (73.9% similar) in 372 aa overlap (22-392:53-418) 10 20 30 40 50 pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNE : :.::.:: : : .. . CCDS57 RALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGI---KESDTGLAPPALWD 30 40 50 60 70 60 70 80 90 100 110 pF1KB6 LNAKVRLLREELQLLQEQGSYVGEVVRA-MDKKKVLVKVHPEGKFVVDVDKNIDINDVTP : : . :. : : : . ... : . : ...:. .:::::.. .. .:. CCDS57 LAADKQTLQSEQPL---QVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEE 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB6 NCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVK . ::.. ..: .: :: :.:: :..:.::. :: :: .:: .::....::.: :. CCDS57 GMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLL 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB6 HPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARM ::: : ::: ::::::.::::::::: :::::..:: :::: :::::::..:::::: CCDS57 HPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARM 200 210 220 230 240 250 240 250 260 270 280 290 pF1KB6 VRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIK ::::: ::: . .::.::::.::..:.. :.:::.:::::::::.::::::. ::: CCDS57 VRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIK 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB6 VIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAEL :.::::: : :: ::.::::.:::::: :. :.: :.:::.:.:.. : : .. .:.: CCDS57 VLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARL 320 330 340 350 360 370 360 370 380 390 400 pF1KB6 MPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK :...:::...:::::::.:.: :: .:..:: :: ::.. CCDS57 CPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN 380 390 400 410 420 430 >>CCDS32139.1 PSMC1 gene_id:5700|Hs108|chr14 (440 aa) initn: 1096 init1: 1073 opt: 1161 Z-score: 1194.1 bits: 230.0 E(32554): 3.4e-60 Smith-Waterman score: 1161; 46.3% identity (74.8% similar) in 393 aa overlap (4-396:44-432) 10 20 30 pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQL :. .. : .. :. : .:.. : CCDS32 GKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 IVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEG . ... : : : . :. : . : ... :. :: . . .: ....:.. . CCDS32 M----EEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGS 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 KFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGG . :.. . .: . . :.: : : . ... .: . .::::..: :::.:. :: ::: CCDS32 EHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 LDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIR ::.::.:::: .:::. ::: .: .:: ::::.:::::::::::::.:::..:. ::.: CCDS32 LDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLR 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 VSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTM : ::::.::..:.: ..::::: .:.::::::.:.::::.::..: ...:::. :.:::: CCDS32 VVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTM 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 LELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHS ::::::::::.. ..:::::::::. :: ::.:::::::::::: :.:... :..::. CCDS32 LELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHT 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 RKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQK .:.:. ..: . :::..:..:::::..::::::..::.:::. . .:. : CCDS32 SRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYK 370 380 390 400 410 420 400 pF1KB6 DSEKNMSIKKLWK .: CCDS32 KQEGTPEGLYL 430 440 >>CCDS81837.1 PSMC1 gene_id:5700|Hs108|chr14 (367 aa) initn: 1096 init1: 1073 opt: 1156 Z-score: 1190.2 bits: 229.0 E(32554): 5.6e-60 Smith-Waterman score: 1156; 49.9% identity (77.9% similar) in 353 aa overlap (44-396:7-359) 20 30 40 50 60 70 pF1KB6 GKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYV : : : . :. : . : ... :. : CCDS81 MEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSV 10 20 30 80 90 100 110 120 130 pF1KB6 GEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDP : . . .: ....:.. .. :.. . .: . . :.: : : . ... .: . .:: CCDS81 GTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDP 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 LVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPG ::..: :::.:. :: :::::.::.:::: .:::. ::: .: .:: ::::.:::::: CCDS81 LVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPG 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 TGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDS :::::::.:::..:. ::.:: ::::.::..:.: ..::::: .:.::::::.:.::::. CCDS81 TGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDA 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 IGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDR ::..: ...:::. :.::::::::::::::.. ..:::::::::. :: ::.::::::: CCDS81 IGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDR 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB6 KIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRE ::::: :.:... :..::. .:.:. ..: . :::..:..:::::..:::: CCDS81 KIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRE 280 290 300 310 320 330 380 390 400 pF1KB6 RRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK ::..::.:::. . .:. : .: CCDS81 RRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 340 350 360 >>CCDS9710.2 PSMC6 gene_id:5706|Hs108|chr14 (403 aa) initn: 1136 init1: 1136 opt: 1141 Z-score: 1174.3 bits: 226.2 E(32554): 4.4e-59 Smith-Waterman score: 1141; 50.3% identity (76.1% similar) in 356 aa overlap (42-397:40-393) 20 30 40 50 60 70 pF1KB6 EEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGS :..:. : .::. . . ...:. :: :. CCDS97 RRLLIMADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQ 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB6 YVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKV ::::.. . ..: .::. ..:: ...: . . :. :::: . :. . :: .: CCDS97 IVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREV 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB6 DPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGP :::: : : . .: ::::..::.:..::::::. .::::. .:: ::: ::::: CCDS97 DPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGP 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB6 PGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEI ::::::::::::: . ::.:..: .: .:.:.:::.::..::.: .::.: : ::::::: CCDS97 PGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEI 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB6 DSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRI :.::. :. :...: :.:::..:::::.:::.. . .:.:::::: : :: :::::::. CCDS97 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRL 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB6 DRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL ::::.. :::.:::::::::. .. :. . :..: : .::....:::::::.:. CCDS97 DRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAI 310 320 330 340 350 360 380 390 400 pF1KB6 RERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK : . :.:::: :: :: ::.: CCDS97 RADHDFVVQEDFMKAVRKVA--DSKKLESKLDYKPV 370 380 390 400 >>CCDS7935.1 PSMC3 gene_id:5702|Hs108|chr11 (439 aa) initn: 1041 init1: 1019 opt: 1055 Z-score: 1085.8 bits: 209.9 E(32554): 3.7e-54 Smith-Waterman score: 1055; 45.1% identity (73.7% similar) in 377 aa overlap (20-393:55-430) 10 20 30 40 pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQR ... : .::: . . ..: ....... CCDS79 EQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNK 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB6 NE---LNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDIN . .. ..:: . . .:.:. . .. : ...:. . . . : .: . CCDS79 TLPYLVSNVIELLDVDPNDQEEDGANI-DLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAE 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB6 DVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIE . :. :.. .::: . . ::.. : :. : :.. : : ::::::::.:. :.: CCDS79 KLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIV 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB6 LPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGE ::..: : :: ::: :::::.:::::::::::::: : .: ::....: .::: :::. CCDS79 LPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGD 210 220 230 240 250 260 230 240 250 260 270 280 pF1KB6 GARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEAT ::..::. :..:.:.::::::.::.:.::..:... ..:: ::::::::::::::::. . CCDS79 GAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPN 270 280 290 300 310 320 290 300 310 320 330 340 pF1KB6 KNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRK ..::: ::::.:::: :::: ::.::::::: :::::: :..:::::::.. .: .. CCDS79 TQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEE 330 340 350 360 370 380 350 360 370 380 390 400 pF1KB6 IAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK .:. .::. :.::.:::: :::. ...:.::. .. .:. : CCDS79 LARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA 390 400 410 420 430 >>CCDS12547.1 PSMC4 gene_id:5704|Hs108|chr19 (418 aa) initn: 1045 init1: 1003 opt: 1052 Z-score: 1083.1 bits: 209.4 E(32554): 5.2e-54 Smith-Waterman score: 1073; 42.5% identity (71.4% similar) in 398 aa overlap (1-398:27-414) 10 20 30 pF1KB6 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLI ... ::: .::. . : : .: . CCDS12 MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 VNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGK ..:...::.. . :.:. ::.. .: .:. ..:.:.. ..: .. CCDS12 IKDEQKNLKK-----EFLHAQ-----EEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSN 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 FVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGL . : . ..:: . . :: :::.. : .: .:: ..: . .. .. :: : :::. CCDS12 YYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGM 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 DKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRV : : .:..:..:::. : ::.. .:: :.:::.::::: :::.::.:::::: .:::: CCDS12 DIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB6 SGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTML :::.:::..::: ::::..: .:.:.::.:::.::::.:...:... .:.: :::: .: CCDS12 VGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILL 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB6 ELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSR :::::.:::. . :.:::::::: : :: :::::::.::::::: :... . :.. . CCDS12 ELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITS 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB6 KMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKD ::::.. ..:. . :::.....: :.:: :.:: : : .::: : :..:: CCDS12 KMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKD 360 370 380 390 400 410 400 pF1KB6 SEKNMSIKKLWK ... CCDS12 EQEHEFYK >>CCDS46076.1 PSMC4 gene_id:5704|Hs108|chr19 (387 aa) initn: 1026 init1: 1003 opt: 1051 Z-score: 1082.6 bits: 209.2 E(32554): 5.6e-54 Smith-Waterman score: 1051; 44.0% identity (72.7% similar) in 366 aa overlap (33-398:18-383) 10 20 30 40 50 60 pF1KB6 LDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREE : :. . .: : . ..:. .:: CCDS46 MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKEE 10 20 30 40 70 80 90 100 110 120 pF1KB6 LQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYT .. .: .:. ..:.:.. ..: ... : . ..:: . . :: :::.. : . CCDS46 VKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 LHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQ : .:: ..: . .. .. :: : :::.: : .:..:..:::. : ::.. .:: CCDS46 LVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDP 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 PKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHA :.:::.::::: :::.::.:::::: .:::: :::.:::..::: ::::..: .:.:.: CCDS46 PRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENA 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILD :.:::.::::.:...:... .:.: :::: .::::::.:::. . :.:::::::: : :: CCDS46 PAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLD 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB6 SALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGV :::::::.::::::: :... . :.. . ::::.. ..:. . :::..... CCDS46 PALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSI 290 300 310 320 330 340 370 380 390 400 pF1KB6 CTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK : :.:: :.:: : : .::: : :..:: ... CCDS46 CQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 350 360 370 380 >>CCDS11859.1 AFG3L2 gene_id:10939|Hs108|chr18 (797 aa) initn: 706 init1: 558 opt: 713 Z-score: 732.3 bits: 145.4 E(32554): 1.8e-34 Smith-Waterman score: 713; 44.2% identity (74.5% similar) in 251 aa overlap (145-391:304-553) 120 130 140 150 160 170 pF1KB6 ALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPEL : .. ..: .. :: : ... .:.:. CCDS11 GPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNF-LKNPKQ 280 290 300 310 320 330 180 190 200 210 220 230 pF1KB6 FEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVREL .. :: :::..: :::::::::::.:.: ... :: :::::... :.: : ::.: CCDS11 YQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDL 340 350 360 370 380 390 240 250 260 270 280 290 pF1KB6 FVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMA :..::..:: :.:.::::..: .: .:. ::.:: . :. .:: ..:::..: :. .. . CCDS11 FALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAG 400 410 420 430 440 450 300 310 320 330 340 350 pF1KB6 TNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGIN----LRKIAEL ::: :::: :::::::.::.: . ::. ..: .:.:.: : ..: .. ::.: : CCDS11 TNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASL 460 470 480 490 500 510 360 370 380 390 400 pF1KB6 MPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK :: :::.: .::.::.. : :. ..:. ::.:. .:. CCDS11 TPGFSGADVANVCNEAALIAARHLSDSINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVA 520 530 540 550 560 570 CCDS11 YHEAGHAVAGWYLEHADPLLKVSIIPRGKGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGR 580 590 600 610 620 630 406 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:23:40 2016 done: Fri Nov 4 23:23:40 2016 Total Scan time: 2.760 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]