FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6591, 380 aa 1>>>pF1KB6591 380 - 380 aa - 380 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9535+/-0.000442; mu= 14.6603+/- 0.028 mean_var=120.0899+/-25.944, 0's: 0 Z-trim(113.8): 763 B-trim: 2627 in 2/48 Lambda= 0.117036 statistics sampled from 22468 (23350) to 22468 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.274), width: 16 Scan time: 8.160 The best scores are: opt bits E(85289) NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 2539 440.1 4e-123 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 2539 440.1 4.3e-123 NP_001269833 (OMIM: 165196) kappa-type opioid rece ( 291) 1927 336.6 4.3e-92 NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 1467 259.1 1.3e-68 NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 1467 259.1 1.3e-68 NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 1463 258.4 2e-68 NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 1463 258.4 2.1e-68 NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 1463 258.4 2.1e-68 NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 1463 258.4 2.1e-68 NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 1463 258.4 2.1e-68 NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 1463 258.5 2.1e-68 NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 1463 258.5 2.1e-68 NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 1463 258.5 2.2e-68 NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 1463 258.5 2.4e-68 NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 1463 258.5 2.4e-68 NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 1395 246.9 5.6e-65 NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 1348 238.9 1.2e-62 NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 1326 235.2 1.5e-61 NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 1322 234.5 2.5e-61 XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 1322 234.5 2.5e-61 NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 1322 234.5 2.5e-61 NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 1322 234.5 2.5e-61 NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 1322 234.5 2.6e-61 XP_016866392 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1322 234.6 2.7e-61 XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1322 234.6 2.7e-61 XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1322 234.6 2.7e-61 XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1322 234.6 2.7e-61 XP_011534153 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1322 234.6 2.7e-61 XP_016866394 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1322 234.6 2.7e-61 XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1322 234.6 2.7e-61 XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 1259 224.0 4.6e-58 NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 1259 224.0 4.6e-58 NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 1259 224.0 4.6e-58 NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 1259 224.0 4.6e-58 XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 1259 224.0 4.7e-58 XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 1259 224.0 4.7e-58 XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 1259 224.0 4.7e-58 NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 1259 224.0 4.8e-58 NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 1216 216.7 6.9e-56 XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 1216 216.7 6.9e-56 NP_001305784 (OMIM: 602548) nociceptin receptor is ( 341) 1173 209.4 1e-53 XP_011527132 (OMIM: 602548) PREDICTED: nociceptin ( 289) 1157 206.6 5.9e-53 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 878 159.7 1.1e-38 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 870 158.3 2.8e-38 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 829 151.4 3.3e-36 NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 769 141.2 3.4e-33 XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 769 141.3 4e-33 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 769 141.3 4e-33 XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 769 141.3 4e-33 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 769 141.3 4e-33 >>NP_000903 (OMIM: 165196) kappa-type opioid receptor is (380 aa) initn: 2539 init1: 2539 opt: 2539 Z-score: 2331.4 bits: 440.1 E(85289): 4e-123 Smith-Waterman score: 2539; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380) 10 20 30 40 50 60 pF1KB6 MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV 310 320 330 340 350 360 370 380 pF1KB6 RNTVQDPAYLRDIDGMNKPV :::::::::::::::::::: NP_000 RNTVQDPAYLRDIDGMNKPV 370 380 >>NP_001305426 (OMIM: 165196) kappa-type opioid receptor (409 aa) initn: 2539 init1: 2539 opt: 2539 Z-score: 2331.0 bits: 440.1 E(85289): 4.3e-123 Smith-Waterman score: 2539; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380) 10 20 30 40 50 60 pF1KB6 MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV 310 320 330 340 350 360 370 380 pF1KB6 RNTVQDPAYLRDIDGMNKPV :::::::::::::::::::: NP_001 RNTVQDPAYLRDIDGMNKPVXLVVEMSSYSSSGREEFNDLGLTQITTAV 370 380 390 400 >>NP_001269833 (OMIM: 165196) kappa-type opioid receptor (291 aa) initn: 1927 init1: 1927 opt: 1927 Z-score: 1774.3 bits: 336.6 E(85289): 4.3e-92 Smith-Waterman score: 1927; 100.0% identity (100.0% similar) in 291 aa overlap (90-380:1-291) 60 70 80 90 100 110 pF1KB6 VIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVY :::::::::::::::::::::::::::::: NP_001 MKTATNIYIFNLALADALVTTTMPFQSTVY 10 20 30 120 130 140 150 160 170 pF1KB6 LMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIIN 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB6 ICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPV 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB6 LIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEAL 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB6 GSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSR 220 230 240 250 260 270 360 370 380 pF1KB6 VRNTVQDPAYLRDIDGMNKPV ::::::::::::::::::::: NP_001 VRNTVQDPAYLRDIDGMNKPV 280 290 >>NP_001008504 (OMIM: 600018) mu-type opioid receptor is (392 aa) initn: 1392 init1: 708 opt: 1467 Z-score: 1353.0 bits: 259.1 E(85289): 1.3e-68 Smith-Waterman score: 1477; 60.7% identity (80.4% similar) in 377 aa overlap (17-380:18-389) 10 20 30 40 pF1KB6 MDSPIQIFRGEPGPTCAPSACLP-PNSSAWFPGWAEPDSNGSA---------GSEDAQL : :.: : :. ..: . .. :.: : :..:. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWV-NLSHLDGNLSDPCGPNRTDLGGRDS-L 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 EPAHISPAIPVIIT--AVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADAL : ::.. . :: :.::.: :::: :: :::.::.:::::::::::::::::::::: NP_001 CPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 VTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL .:.:.::::. :::..:::: .:::::::::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMK ::::: .:::::.: :.:::..:. .. .. :: :. :.:.: : . : .: .: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQG--SIDCTLTFSHPTWYWENL-LK 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 ICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCW ::::::::..::::: ::: ::::::::::.::::.:::::::::::.::::::::.::: NP_001 ICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCW 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 TPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP :::::.....:: . ..: :..:::::::::: :::.::::::::::::::.::.: NP_001 TPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIP 300 310 320 330 340 350 350 360 370 380 pF1KB6 LKMRMERQSTSRVRNTVQD-PAYLRDIDGMNKPV . .:.:...:.:....: :. .: :. : NP_001 TSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQVRSL 360 370 380 390 >>NP_001138758 (OMIM: 600018) mu-type opioid receptor is (420 aa) initn: 1392 init1: 708 opt: 1467 Z-score: 1352.6 bits: 259.1 E(85289): 1.3e-68 Smith-Waterman score: 1477; 60.7% identity (80.4% similar) in 377 aa overlap (17-380:18-389) 10 20 30 40 pF1KB6 MDSPIQIFRGEPGPTCAPSACLP-PNSSAWFPGWAEPDSNGSA---------GSEDAQL : :.: : :. ..: . .. :.: : :..:. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWV-NLSHLDGNLSDPCGPNRTDLGGRDS-L 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 EPAHISPAIPVIIT--AVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADAL : ::.. . :: :.::.: :::: :: :::.::.:::::::::::::::::::::: NP_001 CPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 VTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL .:.:.::::. :::..:::: .:::::::::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMK ::::: .:::::.: :.:::..:. .. .. :: :. :.:.: : . : .: .: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQG--SIDCTLTFSHPTWYWENL-LK 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 ICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCW ::::::::..::::: ::: ::::::::::.::::.:::::::::::.::::::::.::: NP_001 ICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCW 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 TPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP :::::.....:: . ..: :..:::::::::: :::.::::::::::::::.::.: NP_001 TPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIP 300 310 320 330 340 350 350 360 370 380 pF1KB6 LKMRMERQSTSRVRNTVQD-PAYLRDIDGMNKPV . .:.:...:.:....: :. .: :. : NP_001 TSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQVELNLDCHCENAKPWPLSYNAGQSPFP 360 370 380 390 400 410 NP_001 FPGRV 420 >>NP_001138757 (OMIM: 600018) mu-type opioid receptor is (389 aa) initn: 1392 init1: 708 opt: 1463 Z-score: 1349.4 bits: 258.4 E(85289): 2e-68 Smith-Waterman score: 1473; 61.0% identity (80.5% similar) in 374 aa overlap (17-377:18-386) 10 20 30 40 pF1KB6 MDSPIQIFRGEPGPTCAPSACLP-PNSSAWFPGWAEPDSNGSA---------GSEDAQL : :.: : :. ..: . .. :.: : :..:. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWV-NLSHLDGNLSDPCGPNRTDLGGRDS-L 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 EPAHISPAIPVIIT--AVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADAL : ::.. . :: :.::.: :::: :: :::.::.:::::::::::::::::::::: NP_001 CPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 VTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL .:.:.::::. :::..:::: .:::::::::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMK ::::: .:::::.: :.:::..:. .. .. :: :. :.:.: : . : .: .: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS--IDCTLTFSHPTWYWENL-LK 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 ICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCW ::::::::..::::: ::: ::::::::::.::::.:::::::::::.::::::::.::: NP_001 ICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCW 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 TPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP :::::.....:: . ..: :..:::::::::: :::.::::::::::::::.::.: NP_001 TPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIP 300 310 320 330 340 350 350 360 370 380 pF1KB6 LKMRMERQSTSRVRNTVQD-PAYLRDIDGMNKPV . .:.:...:.:....: :. .: : NP_001 TSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQS 360 370 380 >>NP_001138755 (OMIM: 600018) mu-type opioid receptor is (397 aa) initn: 1392 init1: 708 opt: 1463 Z-score: 1349.2 bits: 258.4 E(85289): 2.1e-68 Smith-Waterman score: 1473; 61.0% identity (80.5% similar) in 374 aa overlap (17-377:18-386) 10 20 30 40 pF1KB6 MDSPIQIFRGEPGPTCAPSACLP-PNSSAWFPGWAEPDSNGSA---------GSEDAQL : :.: : :. ..: . .. :.: : :..:. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWV-NLSHLDGNLSDPCGPNRTDLGGRDS-L 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 EPAHISPAIPVIIT--AVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADAL : ::.. . :: :.::.: :::: :: :::.::.:::::::::::::::::::::: NP_001 CPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 VTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL .:.:.::::. :::..:::: .:::::::::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMK ::::: .:::::.: :.:::..:. .. .. :: :. :.:.: : . : .: .: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS--IDCTLTFSHPTWYWENL-LK 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 ICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCW ::::::::..::::: ::: ::::::::::.::::.:::::::::::.::::::::.::: NP_001 ICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCW 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 TPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP :::::.....:: . ..: :..:::::::::: :::.::::::::::::::.::.: NP_001 TPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIP 300 310 320 330 340 350 350 360 370 380 pF1KB6 LKMRMERQSTSRVRNTVQD-PAYLRDIDGMNKPV . .:.:...:.:....: :. .: : NP_001 TSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQRERRQKSDW 360 370 380 390 >>NP_000905 (OMIM: 600018) mu-type opioid receptor isofo (400 aa) initn: 1392 init1: 708 opt: 1463 Z-score: 1349.2 bits: 258.4 E(85289): 2.1e-68 Smith-Waterman score: 1473; 61.0% identity (80.5% similar) in 374 aa overlap (17-377:18-386) 10 20 30 40 pF1KB6 MDSPIQIFRGEPGPTCAPSACLP-PNSSAWFPGWAEPDSNGSA---------GSEDAQL : :.: : :. ..: . .. :.: : :..:. : NP_000 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWV-NLSHLDGNLSDPCGPNRTDLGGRDS-L 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 EPAHISPAIPVIIT--AVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADAL : ::.. . :: :.::.: :::: :: :::.::.:::::::::::::::::::::: NP_000 CPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 VTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL .:.:.::::. :::..:::: .:::::::::::::::::::: :::::::::::::::: NP_000 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMK ::::: .:::::.: :.:::..:. .. .. :: :. :.:.: : . : .: .: NP_000 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS--IDCTLTFSHPTWYWENL-LK 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 ICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCW ::::::::..::::: ::: ::::::::::.::::.:::::::::::.::::::::.::: NP_000 ICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCW 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 TPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP :::::.....:: . ..: :..:::::::::: :::.::::::::::::::.::.: NP_000 TPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIP 300 310 320 330 340 350 350 360 370 380 pF1KB6 LKMRMERQSTSRVRNTVQD-PAYLRDIDGMNKPV . .:.:...:.:....: :. .: : NP_000 TSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP 360 370 380 390 400 >>NP_001138756 (OMIM: 600018) mu-type opioid receptor is (403 aa) initn: 1392 init1: 708 opt: 1463 Z-score: 1349.2 bits: 258.4 E(85289): 2.1e-68 Smith-Waterman score: 1473; 61.0% identity (80.5% similar) in 374 aa overlap (17-377:18-386) 10 20 30 40 pF1KB6 MDSPIQIFRGEPGPTCAPSACLP-PNSSAWFPGWAEPDSNGSA---------GSEDAQL : :.: : :. ..: . .. :.: : :..:. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWV-NLSHLDGNLSDPCGPNRTDLGGRDS-L 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 EPAHISPAIPVIIT--AVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADAL : ::.. . :: :.::.: :::: :: :::.::.:::::::::::::::::::::: NP_001 CPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 VTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL .:.:.::::. :::..:::: .:::::::::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMK ::::: .:::::.: :.:::..:. .. .. :: :. :.:.: : . : .: .: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS--IDCTLTFSHPTWYWENL-LK 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 ICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCW ::::::::..::::: ::: ::::::::::.::::.:::::::::::.::::::::.::: NP_001 ICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCW 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 TPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP :::::.....:: . ..: :..:::::::::: :::.::::::::::::::.::.: NP_001 TPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIP 300 310 320 330 340 350 350 360 370 380 pF1KB6 LKMRMERQSTSRVRNTVQD-PAYLRDIDGMNKPV . .:.:...:.:....: :. .: : NP_001 TSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQGPPAKFVADQLAGSS 360 370 380 390 400 >>NP_001138754 (OMIM: 600018) mu-type opioid receptor is (406 aa) initn: 1392 init1: 708 opt: 1463 Z-score: 1349.1 bits: 258.4 E(85289): 2.1e-68 Smith-Waterman score: 1473; 61.0% identity (80.5% similar) in 374 aa overlap (17-377:18-386) 10 20 30 40 pF1KB6 MDSPIQIFRGEPGPTCAPSACLP-PNSSAWFPGWAEPDSNGSA---------GSEDAQL : :.: : :. ..: . .. :.: : :..:. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWV-NLSHLDGNLSDPCGPNRTDLGGRDS-L 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 EPAHISPAIPVIIT--AVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADAL : ::.. . :: :.::.: :::: :: :::.::.:::::::::::::::::::::: NP_001 CPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 VTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL .:.:.::::. :::..:::: .:::::::::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 DFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMK ::::: .:::::.: :.:::..:. .. .. :: :. :.:.: : . : .: .: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS--IDCTLTFSHPTWYWENL-LK 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 ICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCW ::::::::..::::: ::: ::::::::::.::::.:::::::::::.::::::::.::: NP_001 ICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCW 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 TPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP :::::.....:: . ..: :..:::::::::: :::.::::::::::::::.::.: NP_001 TPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIP 300 310 320 330 340 350 350 360 370 380 pF1KB6 LKMRMERQSTSRVRNTVQD-PAYLRDIDGMNKPV . .:.:...:.:....: :. .: : NP_001 TSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQKIDLFQKSSLLNCEHTKG 360 370 380 390 400 380 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:06:15 2016 done: Sat Nov 5 04:06:16 2016 Total Scan time: 8.160 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]