FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6595, 380 aa 1>>>pF1KB6595 380 - 380 aa - 380 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4662+/-0.000413; mu= 15.7612+/- 0.026 mean_var=79.6070+/-15.721, 0's: 0 Z-trim(112.3): 125 B-trim: 9 in 2/52 Lambda= 0.143747 statistics sampled from 21032 (21165) to 21032 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.248), width: 16 Scan time: 6.420 The best scores are: opt bits E(85289) NP_000631 (OMIM: 300130) interleukin-13 receptor s ( 380) 2675 564.7 1.2e-160 NP_000555 (OMIM: 147851) interleukin-5 receptor su ( 420) 369 86.5 1.2e-16 NP_783853 (OMIM: 147851) interleukin-5 receptor su ( 420) 369 86.5 1.2e-16 XP_011531979 (OMIM: 147851) PREDICTED: interleukin ( 439) 369 86.5 1.3e-16 XP_011531980 (OMIM: 147851) PREDICTED: interleukin ( 439) 369 86.5 1.3e-16 NP_001230028 (OMIM: 147851) interleukin-5 receptor ( 378) 368 86.3 1.3e-16 NP_783851 (OMIM: 147851) interleukin-5 receptor su ( 333) 344 81.3 3.7e-15 NP_783854 (OMIM: 147851) interleukin-5 receptor su ( 333) 344 81.3 3.7e-15 NP_783855 (OMIM: 147851) interleukin-5 receptor su ( 335) 344 81.3 3.7e-15 NP_783852 (OMIM: 147851) interleukin-5 receptor su ( 335) 344 81.3 3.7e-15 NP_001551 (OMIM: 300119) interleukin-13 receptor s ( 427) 328 78.0 4.5e-14 XP_011529638 (OMIM: 300119) PREDICTED: interleukin ( 529) 328 78.1 5.3e-14 NP_000197 (OMIM: 300400,308380,312863) cytokine re ( 369) 316 75.5 2.2e-13 XP_016884996 (OMIM: 300119) PREDICTED: interleukin ( 286) 240 59.7 1e-08 XP_011528206 (OMIM: 138981,614370) PREDICTED: cyto ( 909) 232 58.4 7.9e-08 NP_001191247 (OMIM: 176761,615554,615555) prolacti ( 268) 222 55.9 1.3e-07 NP_001191246 (OMIM: 176761,615554,615555) prolacti ( 288) 222 55.9 1.4e-07 XP_016865135 (OMIM: 176761,615554,615555) PREDICTE ( 309) 222 56.0 1.4e-07 NP_001191244 (OMIM: 176761,615554,615555) prolacti ( 349) 222 56.0 1.6e-07 NP_001191245 (OMIM: 176761,615554,615555) prolacti ( 376) 222 56.0 1.7e-07 NP_000386 (OMIM: 138981,614370) cytokine receptor ( 897) 225 56.9 2.2e-07 XP_006714547 (OMIM: 176761,615554,615555) PREDICTE ( 622) 222 56.2 2.5e-07 XP_011512370 (OMIM: 176761,615554,615555) PREDICTE ( 622) 222 56.2 2.5e-07 XP_011512371 (OMIM: 176761,615554,615555) PREDICTE ( 622) 222 56.2 2.5e-07 NP_000940 (OMIM: 176761,615554,615555) prolactin r ( 622) 222 56.2 2.5e-07 XP_011528207 (OMIM: 138981,614370) PREDICTED: cyto ( 529) 210 53.6 1.2e-06 XP_011526726 (OMIM: 272430,604237) PREDICTED: cyto ( 404) 207 52.9 1.5e-06 XP_011526725 (OMIM: 272430,604237) PREDICTED: cyto ( 419) 207 52.9 1.6e-06 NP_004741 (OMIM: 272430,604237) cytokine receptor- ( 422) 207 52.9 1.6e-06 XP_011526724 (OMIM: 272430,604237) PREDICTED: cyto ( 423) 207 52.9 1.6e-06 XP_011528205 (OMIM: 138981,614370) PREDICTED: cyto ( 915) 210 53.8 1.9e-06 XP_016856693 (OMIM: 601642) PREDICTED: interleukin ( 498) 205 52.6 2.4e-06 NP_001245145 (OMIM: 601642) interleukin-12 recepto ( 635) 205 52.7 2.9e-06 NP_001245143 (OMIM: 601642) interleukin-12 recepto ( 659) 205 52.7 3e-06 XP_016856692 (OMIM: 601642) PREDICTED: interleukin ( 659) 205 52.7 3e-06 NP_001306162 (OMIM: 601642) interleukin-12 recepto ( 659) 205 52.7 3e-06 XP_016856691 (OMIM: 601642) PREDICTED: interleukin ( 700) 205 52.7 3.1e-06 NP_001245144 (OMIM: 601642) interleukin-12 recepto ( 776) 205 52.7 3.4e-06 XP_006710680 (OMIM: 601642) PREDICTED: interleukin ( 776) 205 52.7 3.4e-06 XP_011539686 (OMIM: 601642) PREDICTED: interleukin ( 809) 205 52.7 3.5e-06 NP_001550 (OMIM: 601642) interleukin-12 receptor s ( 862) 205 52.7 3.7e-06 XP_011539685 (OMIM: 601642) PREDICTED: interleukin ( 862) 205 52.7 3.7e-06 XP_005270882 (OMIM: 601642) PREDICTED: interleukin ( 862) 205 52.7 3.7e-06 XP_005270884 (OMIM: 601642) PREDICTED: interleukin ( 862) 205 52.7 3.7e-06 XP_005270885 (OMIM: 601642) PREDICTED: interleukin ( 862) 205 52.7 3.7e-06 XP_005274837 (OMIM: 308385,430000) PREDICTED: inte ( 378) 200 51.5 4e-06 XP_005274488 (OMIM: 308385,430000) PREDICTED: inte ( 378) 200 51.5 4e-06 NP_002174 (OMIM: 308385,430000) interleukin-3 rece ( 378) 200 51.5 4e-06 XP_016885517 (OMIM: 306250,425000) PREDICTED: gran ( 383) 199 51.3 4.6e-06 XP_011543925 (OMIM: 306250,425000) PREDICTED: gran ( 383) 199 51.3 4.6e-06 >>NP_000631 (OMIM: 300130) interleukin-13 receptor subun (380 aa) initn: 2675 init1: 2675 opt: 2675 Z-score: 3004.9 bits: 564.7 E(85289): 1.2e-160 Smith-Waterman score: 2675; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 ALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTG 310 320 330 340 350 360 370 380 pF1KB6 LLLRKPNTYPKMIPEFFCDT :::::::::::::::::::: NP_000 LLLRKPNTYPKMIPEFFCDT 370 380 >>NP_000555 (OMIM: 147851) interleukin-5 receptor subuni (420 aa) initn: 196 init1: 146 opt: 369 Z-score: 419.8 bits: 86.5 E(85289): 1.2e-16 Smith-Waterman score: 422; 27.2% identity (56.9% similar) in 364 aa overlap (27-374:25-373) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD : .:.. :: .: : : :. . :::.: . . NP_000 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ . .. ..::..: . ..: ::.. : :.::. :...:.: .. : . NP_000 Q-RNVNLEYQVKINAPKEDDYETRITES---KCVTILHKGFSASVRTILQ---NDHSLLA 60 70 80 90 100 110 130 140 150 160 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCV----------YYNWQYLL-CSWKPGIGVLLDTNY :::: .. .: : : :.. .. :. ..: : :.: : . ::.: NP_000 SSWA-SAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQY 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 NLFYWYEGLDHALQCVDYIKAD-GQNIGCRFPYLEA-SDYKDFY-ICVNGSSENKPIRSS :.: : . . .: .: : :.::.: :: : .:. . :::::... :: NP_000 FLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 YFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTA : :. : . ::. .: :.. .....: :.. .: .:::::..:.. . . NP_000 DQLFALHAIDQINPPLNVTAEIEGT-RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 TVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWL . .. .. . ::. :. .: . :.::::: . . :.: : :: :. NP_000 EKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWS-QPIYVGNDEHKP--LREWF 290 300 310 320 330 340 350 360 370 380 pF1KB6 PFGFI--LILVIFVTGLLLRKPNTYPKMIPEFFCDT . .. . ..... .:. . . . :..: NP_000 VIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEV 350 360 370 380 390 400 >>NP_783853 (OMIM: 147851) interleukin-5 receptor subuni (420 aa) initn: 196 init1: 146 opt: 369 Z-score: 419.8 bits: 86.5 E(85289): 1.2e-16 Smith-Waterman score: 422; 27.2% identity (56.9% similar) in 364 aa overlap (27-374:25-373) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD : .:.. :: .: : : :. . :::.: . . NP_783 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ . .. ..::..: . ..: ::.. : :.::. :...:.: .. : . NP_783 Q-RNVNLEYQVKINAPKEDDYETRITES---KCVTILHKGFSASVRTILQ---NDHSLLA 60 70 80 90 100 110 130 140 150 160 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCV----------YYNWQYLL-CSWKPGIGVLLDTNY :::: .. .: : : :.. .. :. ..: : :.: : . ::.: NP_783 SSWA-SAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQY 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 NLFYWYEGLDHALQCVDYIKAD-GQNIGCRFPYLEA-SDYKDFY-ICVNGSSENKPIRSS :.: : . . .: .: : :.::.: :: : .:. . :::::... :: NP_783 FLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 YFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTA : :. : . ::. .: :.. .....: :.. .: .:::::..:.. . . NP_783 DQLFALHAIDQINPPLNVTAEIEGT-RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 TVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWL . .. .. . ::. :. .: . :.::::: . . :.: : :: :. NP_783 EKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWS-QPIYVGNDEHKP--LREWF 290 300 310 320 330 340 350 360 370 380 pF1KB6 PFGFI--LILVIFVTGLLLRKPNTYPKMIPEFFCDT . .. . ..... .:. . . . :..: NP_783 VIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEV 350 360 370 380 390 400 >>XP_011531979 (OMIM: 147851) PREDICTED: interleukin-5 r (439 aa) initn: 196 init1: 146 opt: 369 Z-score: 419.5 bits: 86.5 E(85289): 1.3e-16 Smith-Waterman score: 422; 27.2% identity (56.9% similar) in 364 aa overlap (27-374:25-373) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD : .:.. :: .: : : :. . :::.: . . XP_011 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ . .. ..::..: . ..: ::.. : :.::. :...:.: .. : . XP_011 Q-RNVNLEYQVKINAPKEDDYETRITES---KCVTILHKGFSASVRTILQ---NDHSLLA 60 70 80 90 100 110 130 140 150 160 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCV----------YYNWQYLL-CSWKPGIGVLLDTNY :::: .. .: : : :.. .. :. ..: : :.: : . ::.: XP_011 SSWA-SAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQY 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 NLFYWYEGLDHALQCVDYIKAD-GQNIGCRFPYLEA-SDYKDFY-ICVNGSSENKPIRSS :.: : . . .: .: : :.::.: :: : .:. . :::::... :: XP_011 FLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 YFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTA : :. : . ::. .: :.. .....: :.. .: .:::::..:.. . . XP_011 DQLFALHAIDQINPPLNVTAEIEGT-RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 TVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWL . .. .. . ::. :. .: . :.::::: . . :.: : :: :. XP_011 EKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWS-QPIYVGNDEHKP--LREWF 290 300 310 320 330 340 350 360 370 380 pF1KB6 PFGFI--LILVIFVTGLLLRKPNTYPKMIPEFFCDT . .. . ..... .:. . . . :..: XP_011 VIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEVLCIFIYILDS 350 360 370 380 390 400 >>XP_011531980 (OMIM: 147851) PREDICTED: interleukin-5 r (439 aa) initn: 196 init1: 146 opt: 369 Z-score: 419.5 bits: 86.5 E(85289): 1.3e-16 Smith-Waterman score: 422; 27.2% identity (56.9% similar) in 364 aa overlap (27-374:25-373) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD : .:.. :: .: : : :. . :::.: . . XP_011 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ . .. ..::..: . ..: ::.. : :.::. :...:.: .. : . XP_011 Q-RNVNLEYQVKINAPKEDDYETRITES---KCVTILHKGFSASVRTILQ---NDHSLLA 60 70 80 90 100 110 130 140 150 160 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCV----------YYNWQYLL-CSWKPGIGVLLDTNY :::: .. .: : : :.. .. :. ..: : :.: : . ::.: XP_011 SSWA-SAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQY 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 NLFYWYEGLDHALQCVDYIKAD-GQNIGCRFPYLEA-SDYKDFY-ICVNGSSENKPIRSS :.: : . . .: .: : :.::.: :: : .:. . :::::... :: XP_011 FLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 YFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTA : :. : . ::. .: :.. .....: :.. .: .:::::..:.. . . XP_011 DQLFALHAIDQINPPLNVTAEIEGT-RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 TVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWL . .. .. . ::. :. .: . :.::::: . . :.: : :: :. XP_011 EKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWS-QPIYVGNDEHKP--LREWF 290 300 310 320 330 340 350 360 370 380 pF1KB6 PFGFI--LILVIFVTGLLLRKPNTYPKMIPEFFCDT . .. . ..... .:. . . . :..: XP_011 VIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEVLCIFIYILDS 350 360 370 380 390 400 >>NP_001230028 (OMIM: 147851) interleukin-5 receptor sub (378 aa) initn: 231 init1: 146 opt: 368 Z-score: 419.3 bits: 86.3 E(85289): 1.3e-16 Smith-Waterman score: 421; 28.2% identity (56.1% similar) in 351 aa overlap (27-363:25-356) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD : .:.. :: .: : : :. . :::.: . . NP_001 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ . .. ..::..: . ..: ::.. : :.::. :...:.: .. : . NP_001 Q-RNVNLEYQVKINAPKEDDYETRITES---KCVTILHKGFSASVRTILQ---NDHSLLA 60 70 80 90 100 110 130 140 150 160 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCV----------YYNWQYLL-CSWKPGIGVLLDTNY :::: .. .: : : :.. .. :. ..: : :.: : . ::.: NP_001 SSWA-SAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQY 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 NLFYWYEGLDHALQCVDYIKAD-GQNIGCRFPYLEA-SDYKDFY-ICVNGSSENKPIRSS :.: : . . .: .: : :.::.: :: : .:. . :::::... :: NP_001 FLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 YFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTA : :. : . ::. .: :.. .....: :.. .: .:::::..:.. . . NP_001 DQLFALHAIDQINPPLNVTAEIEGT-RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 TVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWL . .. .. . ::. :. .: . :.::::: . . :.: : :: : NP_001 EKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWS-QPIYVGNDEHKP--LREW- 290 300 310 320 330 340 350 360 370 380 pF1KB6 PFGFILILVIFVTGLLLRKPNTYPKMIPEFFCDT :..... . .:: NP_001 ---FVIVIMATICFILLILSLICKIKLGPVRRKLKSSVI 350 360 370 >>NP_783851 (OMIM: 147851) interleukin-5 receptor subuni (333 aa) initn: 231 init1: 146 opt: 344 Z-score: 393.2 bits: 81.3 E(85289): 3.7e-15 Smith-Waterman score: 397; 28.7% identity (56.7% similar) in 314 aa overlap (27-326:25-326) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD : .:.. :: .: : : :. . :::.: . . NP_783 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ . .. ..::..: . ..: ::.. : :.::. :...:.: .. : . NP_783 Q-RNVNLEYQVKINAPKEDDYETRITES---KCVTILHKGFSASVRTILQ---NDHSLLA 60 70 80 90 100 110 130 140 150 160 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCV----------YYNWQYLL-CSWKPGIGVLLDTNY :::: .. .: : : :.. .. :. ..: : :.: : . ::.: NP_783 SSWA-SAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQY 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 NLFYWYEGLDHALQCVDYIKAD-GQNIGCRFPYLEA-SDYKDFY-ICVNGSSENKPIRSS :.: : . . .: .: : :.::.: :: : .:. . :::::... :: NP_783 FLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 YFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTA : :. : . ::. .: :.. .....: :.. .: .:::::..:.. . . NP_783 DQLFALHAIDQINPPLNVTAEIEGT-RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 TVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWL . .. .. . ::. :. .: . :.::::: NP_783 EKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK 290 300 310 320 330 350 360 370 380 pF1KB6 PFGFILILVIFVTGLLLRKPNTYPKMIPEFFCDT >>NP_783854 (OMIM: 147851) interleukin-5 receptor subuni (333 aa) initn: 231 init1: 146 opt: 344 Z-score: 393.2 bits: 81.3 E(85289): 3.7e-15 Smith-Waterman score: 397; 28.7% identity (56.7% similar) in 314 aa overlap (27-326:25-326) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD : .:.. :: .: : : :. . :::.: . . NP_783 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ . .. ..::..: . ..: ::.. : :.::. :...:.: .. : . NP_783 Q-RNVNLEYQVKINAPKEDDYETRITES---KCVTILHKGFSASVRTILQ---NDHSLLA 60 70 80 90 100 110 130 140 150 160 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCV----------YYNWQYLL-CSWKPGIGVLLDTNY :::: .. .: : : :.. .. :. ..: : :.: : . ::.: NP_783 SSWA-SAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQY 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 NLFYWYEGLDHALQCVDYIKAD-GQNIGCRFPYLEA-SDYKDFY-ICVNGSSENKPIRSS :.: : . . .: .: : :.::.: :: : .:. . :::::... :: NP_783 FLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 YFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTA : :. : . ::. .: :.. .....: :.. .: .:::::..:.. . . NP_783 DQLFALHAIDQINPPLNVTAEIEGT-RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 TVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWL . .. .. . ::. :. .: . :.::::: NP_783 EKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK 290 300 310 320 330 350 360 370 380 pF1KB6 PFGFILILVIFVTGLLLRKPNTYPKMIPEFFCDT >>NP_783855 (OMIM: 147851) interleukin-5 receptor subuni (335 aa) initn: 231 init1: 146 opt: 344 Z-score: 393.1 bits: 81.3 E(85289): 3.7e-15 Smith-Waterman score: 397; 28.7% identity (56.7% similar) in 314 aa overlap (27-326:25-326) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD : .:.. :: .: : : :. . :::.: . . NP_783 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ . .. ..::..: . ..: ::.. : :.::. :...:.: .. : . NP_783 Q-RNVNLEYQVKINAPKEDDYETRITES---KCVTILHKGFSASVRTILQ---NDHSLLA 60 70 80 90 100 110 130 140 150 160 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCV----------YYNWQYLL-CSWKPGIGVLLDTNY :::: .. .: : : :.. .. :. ..: : :.: : . ::.: NP_783 SSWA-SAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQY 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 NLFYWYEGLDHALQCVDYIKAD-GQNIGCRFPYLEA-SDYKDFY-ICVNGSSENKPIRSS :.: : . . .: .: : :.::.: :: : .:. . :::::... :: NP_783 FLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 YFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTA : :. : . ::. .: :.. .....: :.. .: .:::::..:.. . . NP_783 DQLFALHAIDQINPPLNVTAEIEGT-RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 TVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWL . .. .. . ::. :. .: . :.::::: NP_783 EKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGFSR 290 300 310 320 330 350 360 370 380 pF1KB6 PFGFILILVIFVTGLLLRKPNTYPKMIPEFFCDT >>NP_783852 (OMIM: 147851) interleukin-5 receptor subuni (335 aa) initn: 231 init1: 146 opt: 344 Z-score: 393.1 bits: 81.3 E(85289): 3.7e-15 Smith-Waterman score: 397; 28.7% identity (56.7% similar) in 314 aa overlap (27-326:25-326) 10 20 30 40 50 60 pF1KB6 MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLD : .:.. :: .: : : :. . :::.: . . NP_783 MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQ . .. ..::..: . ..: ::.. : :.::. :...:.: .. : . NP_783 Q-RNVNLEYQVKINAPKEDDYETRITES---KCVTILHKGFSASVRTILQ---NDHSLLA 60 70 80 90 100 110 130 140 150 160 pF1KB6 SSWAETTYWISPQGIPETKVQDMDCV----------YYNWQYLL-CSWKPGIGVLLDTNY :::: .. .: : : :.. .. :. ..: : :.: : . ::.: NP_783 SSWA-SAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQY 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 NLFYWYEGLDHALQCVDYIKAD-GQNIGCRFPYLEA-SDYKDFY-ICVNGSSENKPIRSS :.: : . . .: .: : :.::.: :: : .:. . :::::... :: NP_783 FLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 YFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTA : :. : . ::. .: :.. .....: :.. .: .:::::..:.. . . NP_783 DQLFALHAIDQINPPLNVTAEIEGT-RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 TVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWL . .. .. . ::. :. .: . :.::::: NP_783 EKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGFSR 290 300 310 320 330 350 360 370 380 pF1KB6 PFGFILILVIFVTGLLLRKPNTYPKMIPEFFCDT 380 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:13:10 2016 done: Sat Nov 5 18:13:11 2016 Total Scan time: 6.420 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]