FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6596, 407 aa 1>>>pF1KB6596 407 - 407 aa - 407 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5877+/-0.00106; mu= 15.2677+/- 0.064 mean_var=131.0642+/-44.473, 0's: 0 Z-trim(104.3): 308 B-trim: 1002 in 2/46 Lambda= 0.112029 statistics sampled from 7250 (7844) to 7250 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.241), width: 16 Scan time: 2.760 The best scores are: opt bits E(32554) CCDS1958.1 TACR1 gene_id:6869|Hs108|chr2 ( 407) 2726 452.9 2.5e-127 CCDS46345.1 TACR1 gene_id:6869|Hs108|chr2 ( 311) 2100 351.6 5.9e-97 CCDS3664.1 TACR3 gene_id:6870|Hs108|chr4 ( 465) 1621 274.4 1.5e-73 CCDS7293.1 TACR2 gene_id:6865|Hs108|chr10 ( 398) 1294 221.5 1.1e-57 CCDS8297.1 GPR83 gene_id:10888|Hs108|chr11 ( 423) 646 116.8 4e-26 CCDS3791.1 NPY2R gene_id:4887|Hs108|chr4 ( 381) 586 107.0 3.1e-23 CCDS7606.1 PRLHR gene_id:2834|Hs108|chr10 ( 370) 548 100.8 2.1e-21 CCDS6152.1 OPRK1 gene_id:4986|Hs108|chr8 ( 380) 486 90.8 2.3e-18 CCDS329.1 OPRD1 gene_id:4985|Hs108|chr1 ( 372) 482 90.2 3.5e-18 CCDS34089.1 NPY1R gene_id:4886|Hs108|chr4 ( 384) 480 89.9 4.5e-18 CCDS13089.1 PROKR2 gene_id:128674|Hs108|chr20 ( 384) 478 89.6 5.6e-18 CCDS1889.1 PROKR1 gene_id:10887|Hs108|chr2 ( 393) 469 88.1 1.6e-17 CCDS47507.1 OPRM1 gene_id:4988|Hs108|chr6 ( 420) 466 87.7 2.3e-17 CCDS11691.1 SSTR2 gene_id:6752|Hs108|chr17 ( 369) 464 87.3 2.6e-17 CCDS55069.1 OPRM1 gene_id:4988|Hs108|chr6 ( 389) 464 87.3 2.7e-17 CCDS47508.1 OPRM1 gene_id:4988|Hs108|chr6 ( 392) 464 87.3 2.7e-17 CCDS47505.1 OPRM1 gene_id:4988|Hs108|chr6 ( 397) 464 87.3 2.7e-17 CCDS55070.1 OPRM1 gene_id:4988|Hs108|chr6 ( 400) 464 87.3 2.8e-17 CCDS47506.1 OPRM1 gene_id:4988|Hs108|chr6 ( 403) 464 87.3 2.8e-17 CCDS47504.1 OPRM1 gene_id:4988|Hs108|chr6 ( 406) 464 87.3 2.8e-17 CCDS43517.1 OPRM1 gene_id:4988|Hs108|chr6 ( 418) 464 87.3 2.8e-17 CCDS43518.1 OPRM1 gene_id:4988|Hs108|chr6 ( 446) 464 87.4 2.9e-17 CCDS47503.1 OPRM1 gene_id:4988|Hs108|chr6 ( 493) 464 87.4 3.1e-17 CCDS12012.1 GALR1 gene_id:2587|Hs108|chr18 ( 349) 449 84.8 1.4e-16 CCDS13556.1 OPRL1 gene_id:4987|Hs108|chr20 ( 370) 447 84.5 1.8e-16 CCDS5196.1 NMBR gene_id:4829|Hs108|chr6 ( 390) 447 84.6 1.8e-16 CCDS13944.1 SSTR3 gene_id:6753|Hs108|chr22 ( 418) 444 84.1 2.7e-16 CCDS14174.1 GRPR gene_id:2925|Hs108|chrX ( 384) 436 82.8 6.2e-16 CCDS11739.1 GALR2 gene_id:8811|Hs108|chr17 ( 387) 434 82.4 7.8e-16 CCDS14656.1 BRS3 gene_id:680|Hs108|chrX ( 399) 434 82.5 7.9e-16 CCDS9666.1 SSTR1 gene_id:6751|Hs108|chr14 ( 391) 429 81.6 1.4e-15 CCDS13557.1 NPBWR2 gene_id:2832|Hs108|chr20 ( 333) 420 80.1 3.4e-15 CCDS12049.1 KISS1R gene_id:84634|Hs108|chr19 ( 398) 418 79.9 4.8e-15 CCDS4321.1 NMUR2 gene_id:56923|Hs108|chr5 ( 415) 417 79.7 5.5e-15 CCDS8290.1 MTNR1B gene_id:4544|Hs108|chr11 ( 362) 405 77.7 1.9e-14 CCDS7950.1 APLNR gene_id:187|Hs108|chr11 ( 380) 404 77.6 2.2e-14 CCDS55068.1 OPRM1 gene_id:4988|Hs108|chr6 ( 319) 402 77.2 2.5e-14 CCDS42856.1 SSTR4 gene_id:6754|Hs108|chr20 ( 388) 403 77.4 2.5e-14 CCDS3687.1 RRH gene_id:10692|Hs108|chr4 ( 337) 399 76.7 3.6e-14 CCDS55071.1 OPRM1 gene_id:4988|Hs108|chr6 ( 300) 398 76.5 3.7e-14 CCDS4395.1 HRH2 gene_id:3274|Hs108|chr5 ( 359) 399 76.7 3.7e-14 CCDS47344.1 HRH2 gene_id:3274|Hs108|chr5 ( 397) 399 76.8 4e-14 CCDS4956.1 HCRTR2 gene_id:3062|Hs108|chr6 ( 444) 399 76.9 4.3e-14 CCDS6151.1 NPBWR1 gene_id:2831|Hs108|chr8 ( 328) 397 76.4 4.4e-14 CCDS3218.1 GHSR gene_id:2693|Hs108|chr3 ( 366) 396 76.3 5.3e-14 CCDS10429.1 SSTR5 gene_id:6755|Hs108|chr16 ( 364) 395 76.1 5.9e-14 CCDS64895.1 OPRK1 gene_id:4986|Hs108|chr8 ( 291) 390 75.2 9e-14 CCDS3063.1 RHO gene_id:6010|Hs108|chr3 ( 348) 387 74.8 1.4e-13 CCDS44012.1 GPR50 gene_id:9248|Hs108|chrX ( 617) 390 75.6 1.4e-13 CCDS14569.1 AGTR2 gene_id:186|Hs108|chrX ( 363) 386 74.7 1.6e-13 >>CCDS1958.1 TACR1 gene_id:6869|Hs108|chr2 (407 aa) initn: 2726 init1: 2726 opt: 2726 Z-score: 2399.6 bits: 452.9 E(32554): 2.5e-127 Smith-Waterman score: 2726; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407) 10 20 30 40 50 60 pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTIST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 NPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTIST 310 320 330 340 350 360 370 380 390 400 pF1KB6 VVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS ::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 VVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS 370 380 390 400 >>CCDS46345.1 TACR1 gene_id:6869|Hs108|chr2 (311 aa) initn: 2100 init1: 2100 opt: 2100 Z-score: 1854.1 bits: 351.6 E(32554): 5.9e-97 Smith-Waterman score: 2100; 100.0% identity (100.0% similar) in 311 aa overlap (1-311:1-311) 10 20 30 40 50 60 pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 NPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTIST ::::::::::: CCDS46 NPIIYCCLNDR 310 >>CCDS3664.1 TACR3 gene_id:6870|Hs108|chr4 (465 aa) initn: 1590 init1: 866 opt: 1621 Z-score: 1433.7 bits: 274.4 E(32554): 1.5e-73 Smith-Waterman score: 1621; 60.1% identity (82.0% similar) in 401 aa overlap (13-404:61-456) 10 20 30 pF1KB6 MDNVLPVDSDLSPNISTNTSEP-----NQFVQPAWQIVLWAA : : :.: ::::::.:.:.::. CCDS36 GAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLTNQFVQPSWRIALWSL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE :: :.:...:.::..:.::::::::::::::::::::::..::::::::.::: ::.:.: CCDS36 AYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSE 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB6 WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVL ::.: ::.:.:::::.:::::::::::.: ::::::: ::.:::::::::.:: ::.: CCDS36 WYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWIL 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB6 ALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYT :.:::::: :: :..::.:..:...::: :.. . .::: : .:.: .:::..: .:: CCDS36 AFLLAFPQCLYSKTKVMPGRTLCFVQWPEGPKQHF--TYHIIVIILVYCFPLLIMGITYT 220 230 240 250 260 220 230 240 250 260 270 pF1KB6 VVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDL .::::::..:::::. :.::::..::::::::::.:: ::::::::.::.:.: : .: CCDS36 IVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQL 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB6 YLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMK :.::::::: .:::::::::::::::::: ::: :::.::: ::::....:. ::.: CCDS36 NRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELK 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB6 STRYLQT-QGSVYKVSRLETTISTVVGAHEEEPEDGPK---ATPSSLDLTSNCSSRSDSK .::. . :.:.: :.:.:. ...: .. . . . ::: : . : :: .:: CCDS36 TTRFHPNRQSSMYTVTRMES-MTVVFDPNDADTTRSSRKKRATPR--DPSFNGCSRRNSK 390 400 410 420 430 440 400 pF1KB6 TMTESFSFSSNVLS . . . :: :. CCDS36 SASATSSFISSPYTSVDEYS 450 460 >>CCDS7293.1 TACR2 gene_id:6865|Hs108|chr10 (398 aa) initn: 1275 init1: 838 opt: 1294 Z-score: 1148.8 bits: 221.5 E(32554): 1.1e-57 Smith-Waterman score: 1294; 50.7% identity (77.6% similar) in 371 aa overlap (8-372:9-379) 10 20 30 40 50 pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILA ....: . .::. . : .:.::..:::.:: ..:...:.::..:.::::: CCDS72 MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 HKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFAS :.:::::::::.::::.:. :::::.. ::.:: :: ::.: .: :.:.:::.:.:.: CCDS72 HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 IYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVV ::::::.: ::::::.::.:::::: .::.:: ::..:: :: :: .:::. . . CCDS72 IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 CMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYH-E :.. ::: . .::. : .::::::: :. ::.:.:.::: .:: .. . . CCDS72 CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 QVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSST ...: .: :: :..:: ::::::::.:..:.: .. :.: .:::::::::..::::::: CCDS72 HLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 MYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRL---- ::::::::::: ::: ::. ::::::... . ::. : :.:. . .... CCDS72 MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA 310 320 330 340 350 360 360 370 380 390 400 pF1KB6 -ETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS .:. : ..... .:.:: CCDS72 GDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI 370 380 390 >>CCDS8297.1 GPR83 gene_id:10888|Hs108|chr11 (423 aa) initn: 601 init1: 317 opt: 646 Z-score: 582.5 bits: 116.8 E(32554): 4e-26 Smith-Waterman score: 646; 34.3% identity (67.0% similar) in 297 aa overlap (34-323:73-363) 10 20 30 40 50 60 pF1KB6 VLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRM : .::. :.: :. :::.: .:. ..:: CCDS82 SWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRM 50 60 70 80 90 100 70 80 90 100 110 120 pF1KB6 RTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSM ...:. :.:::: :. .. .:: ... :.. : .: .:. : .. .: .. CCDS82 HSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTL 110 120 130 140 150 160 130 140 150 160 170 pF1KB6 TAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGY------YSTTETMPSR ::.: ::...:.:::.::.: : . : :::..: ....:.. .. .: . : CCDS82 TAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDI-VR 170 180 190 200 210 220 180 190 200 210 220 230 pF1KB6 VVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGD-SSDRY .:. ..:: : .. : . . .:.:.::::.:. ::. :. :: .. :: ....: CCDS82 SLCLPDFPE-PADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQY 230 240 250 260 270 280 240 250 260 270 280 290 pF1KB6 HEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMS :.:..::...:: ::.::.:.. . :: .. . . . .:.:. :.::: CCDS82 FALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL--LSSKVI--RTNNALYFAFHWFAMS 290 300 310 320 330 300 310 320 330 340 350 pF1KB6 STMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLET :: :::.::: ::. ::. .: . : CCDS82 STCYNPFIYCWLNENFRIELKALLSMCQRPPKPQEDRPPSPVPSFRVAWTEKNDGQRAPL 340 350 360 370 380 390 >>CCDS3791.1 NPY2R gene_id:4887|Hs108|chr4 (381 aa) initn: 444 init1: 263 opt: 586 Z-score: 530.6 bits: 107.0 E(32554): 3.1e-23 Smith-Waterman score: 586; 30.4% identity (62.6% similar) in 342 aa overlap (10-345:31-366) 10 20 30 pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAY .: :. . . ..... :.:: :: CCDS37 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEV--QVVL-ILAY 10 20 30 40 50 40 50 60 70 80 90 pF1KB6 TVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWY :.. .:.:: .:. ... : ::::::.:..::: :. . .. ..::.. .:: CCDS37 CSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWK 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 YGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLAL .: :.. . :: .: ..:..:.::. :.. :. ..: . ..: . : .. CCDS37 MGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISA 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 LLAFPQGY---YSTTETMPSR--VVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY ::: : . :: : .:. :.: .:: . ..:: :: . ...: ::: .:.. CCDS37 LLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISF 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB6 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN .:: . : :: ..:.::.. ..:..::.. :: .::. :::.: : : :. CCDS37 SYTRIWSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDID 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB6 PDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYE-G .. : . .. .. .:: ::. ::..: .:. .: .: :::: ..: : . CCDS37 SQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVS 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB6 LEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSK . .:. . :... CCDS37 VTFKAKKNLEVRKNSGPNDSFTEATNV 360 370 380 >>CCDS7606.1 PRLHR gene_id:2834|Hs108|chr10 (370 aa) initn: 339 init1: 215 opt: 548 Z-score: 497.6 bits: 100.8 E(32554): 2.1e-21 Smith-Waterman score: 548; 32.0% identity (65.3% similar) in 297 aa overlap (22-313:49-343) 10 20 30 40 50 pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIV-LWAAAYTVIVVTSVVGN : : .: . :. : . :.:.::...::: CCDS76 PPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGN 20 30 40 50 60 70 60 70 80 90 100 pF1KB6 VVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE-WYYGLFYCKFHN ... .: .:...:::... :::.... : . . ....:: . . : .: :.. CCDS76 CLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVF 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB6 FFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYS :. ..:..:....:..: :::....:::. :.: . .. .::.:. .::.: . .. CCDS76 FLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHT 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB6 T-TETMPSRV-VCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASE .: : : .: : . . ...: . .. :.:::::: .:. :.. : CCDS76 YHVELKPHDVRLCEEFWGSQERQ--RQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRV 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB6 IPGDSSDRYHEQVSAKRK-VVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQV .:: .. . :.:. . ...:.: .::.::::.:.: :: ..: . : CCDS76 VPGCVTQSQADWDRARRRRTFCLLVVIVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLV 260 270 280 290 300 310 290 300 310 320 330 340 pF1KB6 YLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQG : ::::::. :::.:: :.: :: CCDS76 QLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWPRKIAPHGQNMTVSVVI 320 330 340 350 360 370 >>CCDS6152.1 OPRK1 gene_id:4986|Hs108|chr8 (380 aa) initn: 285 init1: 141 opt: 486 Z-score: 443.3 bits: 90.8 E(32554): 2.3e-18 Smith-Waterman score: 486; 27.9% identity (62.9% similar) in 326 aa overlap (8-325:37-348) 10 20 30 pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAA ::. : . :: . ..:: ... .: CCDS61 IFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAH-ISPAIPVII-TA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVH-- .:.:. :...::: .::..:. . .:.:.:: .. :::.:.: .. :.. : .:. CCDS61 VYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVT---TTMPFQSTVYLM 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 NEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQP---RLSATATKVVIC : : .: ::. . .:.::...: .. :::.:. ::.. : : . :: CCDS61 NSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINIC 130 140 150 160 170 180 160 170 180 190 200 pF1KB6 VIWVLAL---LLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPL ::.:. . :. : .. : . . . : ...:. . .. ..::: .. . .:. CCDS61 -IWLLSSSVGISAIVLGGTKVREDV-DVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPV 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 LVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFL :.: ::.. . : . .. . : .. .. :.......::: .:..:: :.:::.: CCDS61 LIIIVCYTLMILRLKSVRLLSGSREKDRNL----RRITRLVLVVVAVFVVCWTPIHIFIL 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 LPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAG . .. . ... :. : :..... :::.: :.. :. :. : : :. CCDS61 VEALGSTSHSTAALSSYYFCIA-LGYTNSSLNPILYAFLDENFKRCFRD-F-CFPLKMRM 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB6 DYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSR CCDS61 ERQSTSRVRNTVQDPAYLRDIDGMNKPV 360 370 380 >>CCDS329.1 OPRD1 gene_id:4985|Hs108|chr1 (372 aa) initn: 333 init1: 112 opt: 482 Z-score: 439.9 bits: 90.2 E(32554): 3.5e-18 Smith-Waterman score: 482; 28.5% identity (63.0% similar) in 316 aa overlap (13-321:28-334) 10 20 30 40 pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAA---YTVI :. ..:.: : .. : ...: : :... CCDS32 MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPG-ARSASSLALAIAITALYSAV 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 VVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGL .....:::.::. :. . .:.:.:: .. :::.:.: .:. . . . . . : .: CCDS32 CAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSAKYLMETWPFGE 60 70 80 90 100 110 110 120 130 140 150 pF1KB6 FYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQP---RLSATATKVVICVIWVLAL . :: . .:.::...: .. :::.:. ::.. : : : . :: ::::: CCDS32 LLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINIC-IWVLAS 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 LLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVV .. : ...:. . ::::...: :. .. : .::: .. . .:.:.: : .. CCDS32 GVGVPIMVMAVTRPRDGAVVCMLQFPS-PSWYWDTVTKICVFLFAFVVPILIITVCYGLM 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB6 GITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLL-PYINPDLY . : . .. . :. :. . :....:..::: .:..:: :.::: .. .. : CCDS32 LLRLRSVRLLSGSK----EKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRR 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB6 LKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKS . ..: : :..... ::..: :.. :. :.. : CCDS32 DPLVVAALHLCIA-LGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREA 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB6 TRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTES CCDS32 TARERVTACTPSDGPGGGAAA 360 370 >>CCDS34089.1 NPY1R gene_id:4886|Hs108|chr4 (384 aa) initn: 463 init1: 291 opt: 480 Z-score: 438.0 bits: 89.9 E(32554): 4.5e-18 Smith-Waterman score: 480; 29.1% identity (56.5% similar) in 333 aa overlap (28-352:36-368) 10 20 30 40 50 pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWII : .: : :: .... .: ::.... :: CCDS34 FSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIII 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVF : .:.::.::: ..:::.:.. .: . .:.:.. ..: .: .::.. : ... CCDS34 LKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSIT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 ASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSR .::.:.. .: .:.. ::.: : . . : : ::::::. ..: :.. : . CCDS34 VSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 VVCM-------IEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPG : . . . . :. .. : . :: :: :: : : . : : . CCDS34 NVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMM 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 DSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAI :. . . : ... :.. .: .::.::::. :: . : .. . ..: CCDS34 DKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLC 250 260 270 280 290 300 300 310 320 330 340 pF1KB6 MWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGD-YEGLEMKSTRYLQTQGSVY :: :: :::.: :: :. .. : : : : : :: . :.. . .. :. CCDS34 HLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLK 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB6 KVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS ..: CCDS34 QASPVAFKKINNNDDNEKI 370 380 407 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 07:04:37 2016 done: Sun Nov 6 07:04:37 2016 Total Scan time: 2.760 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]