FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6603, 408 aa 1>>>pF1KB6603 408 - 408 aa - 408 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4247+/-0.000416; mu= 8.3080+/- 0.026 mean_var=142.2833+/-28.551, 0's: 0 Z-trim(115.7): 32 B-trim: 413 in 3/52 Lambda= 0.107522 statistics sampled from 26239 (26271) to 26239 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.308), width: 16 Scan time: 7.360 The best scores are: opt bits E(85289) NP_003133 (OMIM: 109090) lupus La protein [Homo sa ( 408) 2674 426.5 6e-119 NP_001281074 (OMIM: 109090) lupus La protein [Homo ( 408) 2674 426.5 6e-119 NP_057732 (OMIM: 612026,615071) la-related protein ( 582) 290 56.8 1.7e-07 NP_056269 (OMIM: 612026,615071) la-related protein ( 582) 290 56.8 1.7e-07 NP_001253968 (OMIM: 612026,615071) la-related prot ( 589) 290 56.8 1.7e-07 XP_016864773 (OMIM: 612059) PREDICTED: la-related ( 824) 217 45.5 0.00056 XP_016864772 (OMIM: 612059) PREDICTED: la-related ( 858) 217 45.5 0.00058 XP_011535920 (OMIM: 612059) PREDICTED: la-related ( 891) 217 45.6 0.0006 XP_005268465 (OMIM: 612059) PREDICTED: la-related ( 891) 217 45.6 0.0006 XP_005268464 (OMIM: 612059) PREDICTED: la-related ( 891) 217 45.6 0.0006 XP_006714839 (OMIM: 612059) PREDICTED: la-related ( 891) 217 45.6 0.0006 XP_006714838 (OMIM: 612059) PREDICTED: la-related ( 955) 217 45.6 0.00063 XP_011535919 (OMIM: 612059) PREDICTED: la-related ( 961) 217 45.6 0.00064 XP_011535918 (OMIM: 612059) PREDICTED: la-related ( 988) 217 45.6 0.00065 NP_056130 (OMIM: 612059) la-related protein 1 [Hom (1019) 217 45.6 0.00067 XP_011535917 (OMIM: 612059) PREDICTED: la-related (1029) 217 45.6 0.00067 XP_005268463 (OMIM: 612059) PREDICTED: la-related (1063) 217 45.6 0.00069 XP_011535916 (OMIM: 612059) PREDICTED: la-related (1070) 217 45.6 0.0007 XP_005268461 (OMIM: 612059) PREDICTED: la-related (1096) 217 45.6 0.00071 >>NP_003133 (OMIM: 109090) lupus La protein [Homo sapien (408 aa) initn: 2674 init1: 2674 opt: 2674 Z-score: 2256.5 bits: 426.5 E(85289): 6e-119 Smith-Waterman score: 2674; 100.0% identity (100.0% similar) in 408 aa overlap (1-408:1-408) 10 20 30 40 50 60 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 DATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 VTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGK 310 320 330 340 350 360 370 380 390 400 pF1KB6 KTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ :::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ 370 380 390 400 >>NP_001281074 (OMIM: 109090) lupus La protein [Homo sap (408 aa) initn: 2674 init1: 2674 opt: 2674 Z-score: 2256.5 bits: 426.5 E(85289): 6e-119 Smith-Waterman score: 2674; 100.0% identity (100.0% similar) in 408 aa overlap (1-408:1-408) 10 20 30 40 50 60 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 DATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 VTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGK 310 320 330 340 350 360 370 380 390 400 pF1KB6 KTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ 370 380 390 400 >>NP_057732 (OMIM: 612026,615071) la-related protein 7 i (582 aa) initn: 223 init1: 107 opt: 290 Z-score: 255.7 bits: 56.8 E(85289): 1.7e-07 Smith-Waterman score: 292; 24.8% identity (56.7% similar) in 427 aa overlap (3-405:24-433) 10 20 30 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQ :. .. . : : .:....::: :: .:.::.:: NP_057 METESGNQEKVMEEESTEKKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQ 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 I-KLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLP : : .:.: . ....::....:::: ..:..:: .:.: ..:.. . :.:::. ::: NP_057 IEKSRDGYVDISLLVSFNKMKKLTTDGKLIARAL-RSSA-VVELDLEGTRIRRK--KPL- 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 EVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKA-FKGSIFVV : .: .:.::.. .: ... . :.. . :.:. :.. . . :: :: NP_057 ---GERPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVE 120 130 140 150 160 170 160 170 180 190 200 pF1KB6 FDSIESAKKFVETPGQKYKETDLLILFKDDYFAK--KNE--------ERKQNKVEAKLRA :.. :.: : .: .. .:. : : : ::. :.:..: . : : NP_057 FETKEQAAKAIEFLNNPPEEAP----RKPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRM 180 190 200 210 220 210 220 230 240 250 pF1KB6 KQEQEAKQKLEE-DAEMKSLEE-KIGCLLKFSGDLDD----QTC----REDLHILFSNHG :.:.. . : :. :. :. . : . . ..:... . : .. .. :. NP_057 KKEDNIQAKEENMDTSNTSISKMKRSRPTSEGSDIESTEPQKQCSKKKKKRDRVEASSLP 230 240 250 260 270 280 260 270 280 290 300 310 pF1KB6 EIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKK :.. :...: . .. :.: . .. . .:.. : . :. : : NP_057 EVRTGKRKRSSSEDAESLAPRS-----KVKKIIQKDIIKEASEASKENRDIEISTEEEKD 290 300 310 320 330 340 320 330 340 350 360 370 pF1KB6 IIEDQQESLNKWKSKGRR-FKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDEN . .. :: : : : .. : . : .. . : .: ... : .. . .. . . . NP_057 TGDLKDSSLLKTKRKHKKKHKERHKMGEEVIPLRVLSKSEWMDLKKEYLALQKASMASLK 350 360 370 380 390 400 380 390 400 pF1KB6 GATGPVKRARE-ETDKEEPASKQQKTENGAGDQ . . .: : :::. : . .:.:. : NP_057 KTISQIKSESEMETDSGVPQNTGMKNEKTANREECRTQEKVNATGPQFVSGVIVKIISTE 410 420 430 440 450 460 >>NP_056269 (OMIM: 612026,615071) la-related protein 7 i (582 aa) initn: 223 init1: 107 opt: 290 Z-score: 255.7 bits: 56.8 E(85289): 1.7e-07 Smith-Waterman score: 292; 24.8% identity (56.7% similar) in 427 aa overlap (3-405:24-433) 10 20 30 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQ :. .. . : : .:....::: :: .:.::.:: NP_056 METESGNQEKVMEEESTEKKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQ 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 I-KLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLP : : .:.: . ....::....:::: ..:..:: .:.: ..:.. . :.:::. ::: NP_056 IEKSRDGYVDISLLVSFNKMKKLTTDGKLIARAL-RSSA-VVELDLEGTRIRRK--KPL- 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 EVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKA-FKGSIFVV : .: .:.::.. .: ... . :.. . :.:. :.. . . :: :: NP_056 ---GERPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVE 120 130 140 150 160 170 160 170 180 190 200 pF1KB6 FDSIESAKKFVETPGQKYKETDLLILFKDDYFAK--KNE--------ERKQNKVEAKLRA :.. :.: : .: .. .:. : : : ::. :.:..: . : : NP_056 FETKEQAAKAIEFLNNPPEEAP----RKPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRM 180 190 200 210 220 210 220 230 240 250 pF1KB6 KQEQEAKQKLEE-DAEMKSLEE-KIGCLLKFSGDLDD----QTC----REDLHILFSNHG :.:.. . : :. :. :. . : . . ..:... . : .. .. :. NP_056 KKEDNIQAKEENMDTSNTSISKMKRSRPTSEGSDIESTEPQKQCSKKKKKRDRVEASSLP 230 240 250 260 270 280 260 270 280 290 300 310 pF1KB6 EIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKK :.. :...: . .. :.: . .. . .:.. : . :. : : NP_056 EVRTGKRKRSSSEDAESLAPRS-----KVKKIIQKDIIKEASEASKENRDIEISTEEEKD 290 300 310 320 330 340 320 330 340 350 360 370 pF1KB6 IIEDQQESLNKWKSKGRR-FKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDEN . .. :: : : : .. : . : .. . : .: ... : .. . .. . . . NP_056 TGDLKDSSLLKTKRKHKKKHKERHKMGEEVIPLRVLSKSEWMDLKKEYLALQKASMASLK 350 360 370 380 390 400 380 390 400 pF1KB6 GATGPVKRARE-ETDKEEPASKQQKTENGAGDQ . . .: : :::. : . .:.:. : NP_056 KTISQIKSESEMETDSGVPQNTGMKNEKTANREECRTQEKVNATGPQFVSGVIVKIISTE 410 420 430 440 450 460 >>NP_001253968 (OMIM: 612026,615071) la-related protein (589 aa) initn: 223 init1: 107 opt: 290 Z-score: 255.6 bits: 56.8 E(85289): 1.7e-07 Smith-Waterman score: 292; 24.8% identity (56.7% similar) in 427 aa overlap (3-405:31-440) 10 20 30 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPR :. .. . : : .:....::: :: . NP_001 MIPNIEGMETESGNQEKVMEEESTEKKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 DKFLKEQI-KLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRR :.::.::: : .:.: . ....::....:::: ..:..:: .:.: ..:.. . :.::: NP_001 DRFLREQIEKSRDGYVDISLLVSFNKMKKLTTDGKLIARAL-RSSA-VVELDLEGTRIRR 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 SPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKA-F . ::: : .: .:.::.. .: ... . :.. . :.:. :.. . . NP_001 K--KPL----GERPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDP 120 130 140 150 160 170 160 170 180 190 200 pF1KB6 KGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAK--KNE--------ERKQNK :: :: :.. :.: : .: .. .:. : : : ::. :.:..: NP_001 KGFAFVEFETKEQAAKAIEFLNNPPEEAP----RKPGIFPKTVKNKPIPALRVVEEKKKK 180 190 200 210 220 210 220 230 240 250 pF1KB6 VEAKLRAKQEQEAKQKLEE-DAEMKSLEE-KIGCLLKFSGDLDD----QTC----REDLH . : : :.:.. . : :. :. :. . : . . ..:... . : .. . NP_001 KKKKGRMKKEDNIQAKEENMDTSNTSISKMKRSRPTSEGSDIESTEPQKQCSKKKKKRDR 230 240 250 260 270 280 260 270 280 290 300 310 pF1KB6 ILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEV . :. :.. :...: . .. :.: . .. . .:.. : . :. NP_001 VEASSLPEVRTGKRKRSSSEDAESLAPRS-----KVKKIIQKDIIKEASEASKENRDIEI 290 300 310 320 330 340 320 330 340 350 360 pF1KB6 EKEALKKIIEDQQESLNKWKSKGRR-FKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDE : : . .. :: : : : .. : . : .. . : .: ... : .. . .. NP_001 STEEEKDTGDLKDSSLLKTKRKHKKKHKERHKMGEEVIPLRVLSKSEWMDLKKEYLALQK 350 360 370 380 390 400 370 380 390 400 pF1KB6 HDEHDENGATGPVKRARE-ETDKEEPASKQQKTENGAGDQ . . . . . .: : :::. : . .:.:. : NP_001 ASMASLKKTISQIKSESEMETDSGVPQNTGMKNEKTANREECRTQEKVNATGPQFVSGVI 410 420 430 440 450 460 NP_001 VKIISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTEINKK 470 480 490 500 510 520 >>XP_016864773 (OMIM: 612059) PREDICTED: la-related prot (824 aa) initn: 89 init1: 89 opt: 217 Z-score: 192.3 bits: 45.5 E(85289): 0.00056 Smith-Waterman score: 217; 25.5% identity (58.0% similar) in 243 aa overlap (13-242:131-360) 10 20 30 40 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKL :. : .::::::. :: :: ::.... XP_016 GPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDA 110 120 130 140 150 160 50 60 70 80 90 100 pF1KB6 DEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSK-PLPEVT : :..:. .. .:.:.. ::::...: ::. :: ..:: ..:.. :. : : ::: .. XP_016 D-GFLPITLIASFHRVQALTTDISLIFAALKDSK--VVEIVDEKVRRREEPEKWPLPPIV 170 180 190 200 210 110 120 130 140 150 pF1KB6 DEYKNDVKN---------RSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKG : ..: .. :. : : :... . . .. ... .:: :.... XP_016 DYSQTDFSQLLNCPEFVPRQHYQK--ETESAPGSPRAVTPVPTKTEEVSNLKTLPKGLSA 220 230 240 250 260 270 160 170 180 190 200 pF1KB6 SIFVVFDS---IESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQ :. .:: :: :. .:.. : ... :.. . .: . . : XP_016 SL-PDLDSENWIEVKKRPRPSPARPKKS-------EESRFSHLTSLPQQLPSQQLMSKDQ 280 290 300 310 320 210 220 230 240 250 260 pF1KB6 EQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAK ... . . : ::.... . . . .: . .: XP_016 DEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTPHYMRRHPGG 330 340 350 360 370 380 270 280 290 300 310 320 pF1KB6 EGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKW XP_016 DRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQ 390 400 410 420 430 440 >>XP_016864772 (OMIM: 612059) PREDICTED: la-related prot (858 aa) initn: 89 init1: 89 opt: 217 Z-score: 192.1 bits: 45.5 E(85289): 0.00058 Smith-Waterman score: 217; 25.5% identity (58.0% similar) in 243 aa overlap (13-242:165-394) 10 20 30 40 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKL :. : .::::::. :: :: ::.... XP_016 GPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDA 140 150 160 170 180 190 50 60 70 80 90 100 pF1KB6 DEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSK-PLPEVT : :..:. .. .:.:.. ::::...: ::. :: ..:: ..:.. :. : : ::: .. XP_016 D-GFLPITLIASFHRVQALTTDISLIFAALKDSK--VVEIVDEKVRRREEPEKWPLPPIV 200 210 220 230 240 250 110 120 130 140 150 pF1KB6 DEYKNDVKN---------RSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKG : ..: .. :. : : :... . . .. ... .:: :.... XP_016 DYSQTDFSQLLNCPEFVPRQHYQK--ETESAPGSPRAVTPVPTKTEEVSNLKTLPKGLSA 260 270 280 290 300 160 170 180 190 200 pF1KB6 SIFVVFDS---IESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQ :. .:: :: :. .:.. : ... :.. . .: . . : XP_016 SL-PDLDSENWIEVKKRPRPSPARPKKS-------EESRFSHLTSLPQQLPSQQLMSKDQ 310 320 330 340 350 360 210 220 230 240 250 260 pF1KB6 EQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAK ... . . : ::.... . . . .: . .: XP_016 DEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTPHYMRRHPGG 370 380 390 400 410 420 270 280 290 300 310 320 pF1KB6 EGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKW XP_016 DRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQ 430 440 450 460 470 480 >>XP_011535920 (OMIM: 612059) PREDICTED: la-related prot (891 aa) initn: 89 init1: 89 opt: 217 Z-score: 191.9 bits: 45.6 E(85289): 0.0006 Smith-Waterman score: 217; 25.5% identity (58.0% similar) in 243 aa overlap (13-242:198-427) 10 20 30 40 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKL :. : .::::::. :: :: ::.... XP_011 GPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDA 170 180 190 200 210 220 50 60 70 80 90 100 pF1KB6 DEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSK-PLPEVT : :..:. .. .:.:.. ::::...: ::. :: ..:: ..:.. :. : : ::: .. XP_011 D-GFLPITLIASFHRVQALTTDISLIFAALKDSK--VVEIVDEKVRRREEPEKWPLPPIV 230 240 250 260 270 280 110 120 130 140 150 pF1KB6 DEYKNDVKN---------RSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKG : ..: .. :. : : :... . . .. ... .:: :.... XP_011 DYSQTDFSQLLNCPEFVPRQHYQK--ETESAPGSPRAVTPVPTKTEEVSNLKTLPKGLSA 290 300 310 320 330 340 160 170 180 190 200 pF1KB6 SIFVVFDS---IESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQ :. .:: :: :. .:.. : ... :.. . .: . . : XP_011 SL-PDLDSENWIEVKKRPRPSPARPKKS-------EESRFSHLTSLPQQLPSQQLMSKDQ 350 360 370 380 390 210 220 230 240 250 260 pF1KB6 EQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAK ... . . : ::.... . . . .: . .: XP_011 DEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTPHYMRRHPGG 400 410 420 430 440 450 270 280 290 300 310 320 pF1KB6 EGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKW XP_011 DRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQ 460 470 480 490 500 510 >>XP_005268465 (OMIM: 612059) PREDICTED: la-related prot (891 aa) initn: 89 init1: 89 opt: 217 Z-score: 191.9 bits: 45.6 E(85289): 0.0006 Smith-Waterman score: 217; 25.5% identity (58.0% similar) in 243 aa overlap (13-242:198-427) 10 20 30 40 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKL :. : .::::::. :: :: ::.... XP_005 GPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDA 170 180 190 200 210 220 50 60 70 80 90 100 pF1KB6 DEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSK-PLPEVT : :..:. .. .:.:.. ::::...: ::. :: ..:: ..:.. :. : : ::: .. XP_005 D-GFLPITLIASFHRVQALTTDISLIFAALKDSK--VVEIVDEKVRRREEPEKWPLPPIV 230 240 250 260 270 280 110 120 130 140 150 pF1KB6 DEYKNDVKN---------RSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKG : ..: .. :. : : :... . . .. ... .:: :.... XP_005 DYSQTDFSQLLNCPEFVPRQHYQK--ETESAPGSPRAVTPVPTKTEEVSNLKTLPKGLSA 290 300 310 320 330 340 160 170 180 190 200 pF1KB6 SIFVVFDS---IESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQ :. .:: :: :. .:.. : ... :.. . .: . . : XP_005 SL-PDLDSENWIEVKKRPRPSPARPKKS-------EESRFSHLTSLPQQLPSQQLMSKDQ 350 360 370 380 390 210 220 230 240 250 260 pF1KB6 EQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAK ... . . : ::.... . . . .: . .: XP_005 DEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTPHYMRRHPGG 400 410 420 430 440 450 270 280 290 300 310 320 pF1KB6 EGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKW XP_005 DRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQ 460 470 480 490 500 510 >>XP_005268464 (OMIM: 612059) PREDICTED: la-related prot (891 aa) initn: 89 init1: 89 opt: 217 Z-score: 191.9 bits: 45.6 E(85289): 0.0006 Smith-Waterman score: 217; 25.5% identity (58.0% similar) in 243 aa overlap (13-242:198-427) 10 20 30 40 pF1KB6 MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKL :. : .::::::. :: :: ::.... XP_005 GPRTPKYMNNITYYFDNVSSTELYSVDQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDA 170 180 190 200 210 220 50 60 70 80 90 100 pF1KB6 DEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSK-PLPEVT : :..:. .. .:.:.. ::::...: ::. :: ..:: ..:.. :. : : ::: .. XP_005 D-GFLPITLIASFHRVQALTTDISLIFAALKDSK--VVEIVDEKVRRREEPEKWPLPPIV 230 240 250 260 270 280 110 120 130 140 150 pF1KB6 DEYKNDVKN---------RSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKG : ..: .. :. : : :... . . .. ... .:: :.... XP_005 DYSQTDFSQLLNCPEFVPRQHYQK--ETESAPGSPRAVTPVPTKTEEVSNLKTLPKGLSA 290 300 310 320 330 340 160 170 180 190 200 pF1KB6 SIFVVFDS---IESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQ :. .:: :: :. .:.. : ... :.. . .: . . : XP_005 SL-PDLDSENWIEVKKRPRPSPARPKKS-------EESRFSHLTSLPQQLPSQQLMSKDQ 350 360 370 380 390 210 220 230 240 250 260 pF1KB6 EQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAK ... . . : ::.... . . . .: . .: XP_005 DEQEELDFLFDEEMEQMDGRKNTFTAWSDEESDYEIDDRDVNKILIVTQTPHYMRRHPGG 400 410 420 430 440 450 270 280 290 300 310 320 pF1KB6 EGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKW XP_005 DRTGNHTSRAKMSAELAKVINDGLFYYEQDLWAEKFEPEYSQIKQEVENFKKVNMISREQ 460 470 480 490 500 510 408 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:31:25 2016 done: Sat Nov 5 13:31:26 2016 Total Scan time: 7.360 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]