FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6605, 393 aa
1>>>pF1KB6605 393 - 393 aa - 393 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6335+/-0.000322; mu= 14.2781+/- 0.020
mean_var=174.1313+/-35.354, 0's: 0 Z-trim(121.1): 22 B-trim: 150 in 1/52
Lambda= 0.097193
statistics sampled from 37307 (37332) to 37307 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.438), width: 16
Scan time: 7.010
The best scores are: opt bits E(85289)
NP_001018079 (OMIM: 607378) plasminogen activator ( 393) 2706 391.1 2.4e-108
NP_056455 (OMIM: 607378) plasminogen activator inh ( 387) 2643 382.3 1.1e-105
NP_001018077 (OMIM: 607378) plasminogen activator ( 408) 1636 241.1 3.6e-63
NP_001018078 (OMIM: 607378) plasminogen activator ( 402) 1616 238.3 2.5e-62
>>NP_001018079 (OMIM: 607378) plasminogen activator inhi (393 aa)
initn: 2706 init1: 2706 opt: 2706 Z-score: 2066.2 bits: 391.1 E(85289): 2.4e-108
Smith-Waterman score: 2706; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:1-393)
10 20 30 40 50 60
pF1KB6 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG
310 320 330 340 350 360
370 380 390
pF1KB6 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
:::::::::::::::::::::::::::::::::
NP_001 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
370 380 390
>>NP_056455 (OMIM: 607378) plasminogen activator inhibit (387 aa)
initn: 1678 init1: 1402 opt: 2643 Z-score: 2018.6 bits: 382.3 E(85289): 1.1e-105
Smith-Waterman score: 2643; 98.5% identity (98.5% similar) in 393 aa overlap (1-393:1-387)
10 20 30 40 50 60
pF1KB6 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_056 RGDGFDSRGKREFDRHSGSDRS------GLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT
190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB6 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG
300 310 320 330 340 350
370 380 390
pF1KB6 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
:::::::::::::::::::::::::::::::::
NP_056 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
360 370 380
>>NP_001018077 (OMIM: 607378) plasminogen activator inhi (408 aa)
initn: 1952 init1: 1604 opt: 1636 Z-score: 1255.2 bits: 241.1 E(85289): 3.6e-63
Smith-Waterman score: 2666; 96.3% identity (96.3% similar) in 408 aa overlap (1-393:1-408)
10 20 30 40 50 60
pF1KB6 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELT--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQK
190 200 210 220 230 240
240 250 260 270 280
pF1KB6 -------DLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QISYNYSDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB6 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
310 320 330 340 350 360
350 360 370 380 390
pF1KB6 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
370 380 390 400
>>NP_001018078 (OMIM: 607378) plasminogen activator inhi (402 aa)
initn: 1750 init1: 1402 opt: 1616 Z-score: 1240.1 bits: 238.3 E(85289): 2.5e-62
Smith-Waterman score: 2603; 94.9% identity (94.9% similar) in 408 aa overlap (1-393:1-402)
10 20 30 40 50 60
pF1KB6 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELT--------
:::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 RGDGFDSRGKREFDRHSGSDRS------GLKHEDKRGGSGSHNWGTVKDELTESPKYIQK
190 200 210 220 230
240 250 260 270 280
pF1KB6 -------DLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QISYNYSDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB6 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
300 310 320 330 340 350
350 360 370 380 390
pF1KB6 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
360 370 380 390 400
393 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:32:29 2016 done: Sat Nov 5 11:32:30 2016
Total Scan time: 7.010 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]