FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6607, 409 aa 1>>>pF1KB6607 409 - 409 aa - 409 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.0985+/-0.000401; mu= -7.7901+/- 0.025 mean_var=329.3157+/-65.959, 0's: 0 Z-trim(121.8): 10 B-trim: 64 in 1/60 Lambda= 0.070675 statistics sampled from 38874 (38886) to 38874 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.456), width: 16 Scan time: 6.400 The best scores are: opt bits E(85289) NP_002865 (OMIM: 600062) UV excision repair protei ( 409) 2597 278.1 2.7e-74 NP_001231642 (OMIM: 600062) UV excision repair pro ( 388) 2459 264.0 4.5e-70 NP_001231653 (OMIM: 600062) UV excision repair pro ( 337) 2150 232.5 1.2e-60 NP_001257292 (OMIM: 600061) UV excision repair pro ( 308) 467 60.8 5.2e-09 NP_001257291 (OMIM: 600061) UV excision repair pro ( 362) 467 60.9 5.9e-09 NP_005044 (OMIM: 600061) UV excision repair protei ( 363) 467 60.9 5.9e-09 >>NP_002865 (OMIM: 600062) UV excision repair protein RA (409 aa) initn: 2597 init1: 2597 opt: 2597 Z-score: 1454.7 bits: 278.1 E(85289): 2.7e-74 Smith-Waterman score: 2597; 100.0% identity (100.0% similar) in 409 aa overlap (1-409:1-409) 10 20 30 40 50 60 pF1KB6 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALAPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALAPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 STPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFEDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 STPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFEDA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAVVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSLLP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 ALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMNYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMNYI 310 320 330 340 350 360 370 380 390 400 pF1KB6 QVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED ::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED 370 380 390 400 >>NP_001231642 (OMIM: 600062) UV excision repair protein (388 aa) initn: 2459 init1: 2459 opt: 2459 Z-score: 1379.0 bits: 264.0 E(85289): 4.5e-70 Smith-Waterman score: 2459; 100.0% identity (100.0% similar) in 387 aa overlap (23-409:2-388) 10 20 30 40 50 60 pF1KB6 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALK :::::::::::::::::::::::::::::::::::::: NP_001 MVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALK 10 20 30 70 80 90 100 110 120 pF1KB6 EYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALAPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALAPT 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 STPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFEDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFEDA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 TSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAVVD 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 PPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSLLP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 ALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMNYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMNYI 280 290 300 310 320 330 370 380 390 400 pF1KB6 QVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED 340 350 360 370 380 >>NP_001231653 (OMIM: 600062) UV excision repair protein (337 aa) initn: 2150 init1: 2150 opt: 2150 Z-score: 1209.6 bits: 232.5 E(85289): 1.2e-60 Smith-Waterman score: 2150; 100.0% identity (100.0% similar) in 337 aa overlap (73-409:1-337) 50 60 70 80 90 100 pF1KB6 GQKLIYAGKILNDDTALKEYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSS :::::::::::::::::::::::::::::: NP_001 MVTKPKAVSTPAPATTQQSAPASTTAVTSS 10 20 30 110 120 130 140 150 160 pF1KB6 TTTTVAQAPTPVPALAPTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTTTVAQAPTPVPALAPTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPT 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 ATDSTSGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATDSTSGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAV 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 EYLLMGIPGDRESQAVVDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYLLMGIPGDRESQAVVDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQ 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 PQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGG 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB6 GGGSGGIAEAGSGHMNYIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGGSGGIAEAGSGHMNYIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLL 280 290 300 310 320 330 pF1KB6 QQNFDED ::::::: NP_001 QQNFDED >>NP_001257292 (OMIM: 600061) UV excision repair protein (308 aa) initn: 965 init1: 409 opt: 467 Z-score: 282.7 bits: 60.8 E(85289): 5.2e-09 Smith-Waterman score: 1054; 50.9% identity (64.9% similar) in 407 aa overlap (3-409:5-308) 10 20 30 40 50 pF1KB6 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTA .:::::::::::: ..:.::::.::::::.:::.:::::::::::::::::.::. NP_001 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LKEYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALA ...:.::::::::::::: :: ::: : :. : NP_001 IRDYRIDEKNFVVVMVTKTKA-------GQGTSAP-----------------PEASPTAA 70 80 90 120 130 140 150 160 170 pF1KB6 PTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFE : :. .:. :: ... :.: :: : ....:.:. : : : ... .::.:.: : NP_001 PESS-TSFPPAPTSGMSHPPPA-AREDKSPSEESAPTTSPESVSGSVPSSGSSGRE---E 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 DATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAV ::.:.::::. ::.:.:::::::::::.:.::::::.::: ::::::: ::::. : NP_001 DAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPE---- 160 170 180 190 200 240 250 260 270 280 290 pF1KB6 VDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSL : . :. : : :. :: .: : .::::::.:::::.:::.:::::.: NP_001 --PEH----GSVQESQVSEQPATEAA-------GENPLEFLRDQPQFQNMRQVIQQNPAL 210 220 230 240 250 300 310 320 330 340 350 pF1KB6 LPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMN :::::::.:.::::::: NP_001 LPALLQQLGQENPQLLQ------------------------------------------- 260 270 360 370 380 390 400 pF1KB6 YIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED ::::::::.:::::::::::::::::::::.::::.. NP_001 --------------LKALGFPESLVIQAYFACEKNENLAANFLLSQNFDDE 280 290 300 >>NP_001257291 (OMIM: 600061) UV excision repair protein (362 aa) initn: 1398 init1: 400 opt: 467 Z-score: 281.7 bits: 60.9 E(85289): 5.9e-09 Smith-Waterman score: 1355; 59.2% identity (75.2% similar) in 407 aa overlap (3-409:5-362) 10 20 30 40 50 pF1KB6 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTA .:::::::::::: ..:.::::.::::::.:::.:::::::::::::::::.::. NP_001 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LKEYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALA ...:.::::::::::::: :: ::: : :. : NP_001 IRDYRIDEKNFVVVMVTKTKA-------GQGTSAP-----------------PEASPTAA 70 80 90 120 130 140 150 160 170 pF1KB6 PTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFE : :. .:. :: ... :.: :: : ....:.:. : : : ... .::.:.: : NP_001 PESS-TSFPPAPTSGMSHPPPA-AREDKSPSEESAPTTSPESVSGSVPSSGSSGRE---E 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 DATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAV ::.:.::::. ::.:.:::::::::::.:.::::::.::: ::::::: ::::. : NP_001 DAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPE---- 160 170 180 190 200 240 250 260 270 280 290 pF1KB6 VDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSL : . :. : : :. : : .: .::::::.:::::.:::.:::::.: NP_001 --PEH----GSVQESQVSEQPA--------TEAGENPLEFLRDQPQFQNMRQVIQQNPAL 210 220 230 240 250 300 310 320 330 340 350 pF1KB6 LPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMN :::::::.:.::::::::::.:::.:::::::: : . . : :.:.: . .:: NP_001 LPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE-VGAIGEEAP-QMN 260 270 280 290 300 310 360 370 380 390 400 pF1KB6 YIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED ::::::::::::::::::::::.:::::::::::::::::::::.::::.. NP_001 YIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFDDE 320 330 340 350 360 >>NP_005044 (OMIM: 600061) UV excision repair protein RA (363 aa) initn: 1399 init1: 400 opt: 467 Z-score: 281.7 bits: 60.9 E(85289): 5.9e-09 Smith-Waterman score: 1361; 59.5% identity (75.4% similar) in 407 aa overlap (3-409:5-363) 10 20 30 40 50 pF1KB6 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTA .:::::::::::: ..:.::::.::::::.:::.:::::::::::::::::.::. NP_005 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LKEYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALA ...:.::::::::::::: :: ::: : :. : NP_005 IRDYRIDEKNFVVVMVTKTKA-------GQGTSAP-----------------PEASPTAA 70 80 90 120 130 140 150 160 170 pF1KB6 PTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFE : :. .:. :: ... :.: :: : ....:.:. : : : ... .::.:.: : NP_005 PESS-TSFPPAPTSGMSHPPPA-AREDKSPSEESAPTTSPESVSGSVPSSGSSGRE---E 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 DATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAV ::.:.::::. ::.:.:::::::::::.:.::::::.::: ::::::: ::::. : NP_005 DAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPE---- 160 170 180 190 200 240 250 260 270 280 290 pF1KB6 VDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSL : . :. : : :. :: .: : .::::::.:::::.:::.:::::.: NP_005 --PEH----GSVQESQVSEQPATEAA-------GENPLEFLRDQPQFQNMRQVIQQNPAL 210 220 230 240 250 300 310 320 330 340 350 pF1KB6 LPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMN :::::::.:.::::::::::.:::.:::::::: : . . : :.:.: . .:: NP_005 LPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE-VGAIGEEAP-QMN 260 270 280 290 300 310 360 370 380 390 400 pF1KB6 YIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED ::::::::::::::::::::::.:::::::::::::::::::::.::::.. NP_005 YIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFDDE 320 330 340 350 360 409 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:04:27 2016 done: Sat Nov 5 11:04:28 2016 Total Scan time: 6.400 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]