FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6611, 412 aa 1>>>pF1KB6611 412 - 412 aa - 412 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8979+/-0.000796; mu= 20.0891+/- 0.048 mean_var=76.7236+/-15.043, 0's: 0 Z-trim(108.0): 63 B-trim: 20 in 1/52 Lambda= 0.146423 statistics sampled from 9857 (9924) to 9857 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.305), width: 16 Scan time: 2.450 The best scores are: opt bits E(32554) CCDS14304.1 SUV39H1 gene_id:6839|Hs108|chrX ( 412) 2894 620.8 7.4e-178 CCDS65252.1 SUV39H1 gene_id:6839|Hs108|chrX ( 423) 2870 615.7 2.5e-176 CCDS53494.1 SUV39H2 gene_id:79723|Hs108|chr10 ( 410) 1590 345.3 6.1e-95 CCDS7104.1 SUV39H2 gene_id:79723|Hs108|chr10 ( 350) 1398 304.7 8.9e-83 CCDS53493.1 SUV39H2 gene_id:79723|Hs108|chr10 ( 230) 530 121.2 1e-27 CCDS7050.2 EHMT1 gene_id:79813|Hs108|chr9 (1298) 537 123.4 1.3e-27 CCDS4726.1 EHMT2 gene_id:10919|Hs108|chr6 (1176) 531 122.0 2.9e-27 CCDS4725.1 EHMT2 gene_id:10919|Hs108|chr6 (1210) 531 122.1 2.9e-27 CCDS75425.1 EHMT2 gene_id:10919|Hs108|chr6 (1233) 531 122.1 3e-27 CCDS63528.1 SETMAR gene_id:6419|Hs108|chr3 ( 365) 467 108.0 1.5e-23 CCDS2563.2 SETMAR gene_id:6419|Hs108|chr3 ( 684) 467 108.3 2.3e-23 CCDS82129.1 EZH1 gene_id:2145|Hs108|chr17 ( 707) 347 83.0 1e-15 CCDS82130.1 EZH1 gene_id:2145|Hs108|chr17 ( 738) 347 83.0 1e-15 CCDS32659.1 EZH1 gene_id:2145|Hs108|chr17 ( 747) 347 83.0 1e-15 CCDS56517.1 EZH2 gene_id:2146|Hs108|chr7 ( 695) 334 80.2 6.6e-15 CCDS5892.1 EZH2 gene_id:2146|Hs108|chr7 ( 707) 334 80.2 6.7e-15 CCDS56518.1 EZH2 gene_id:2146|Hs108|chr7 ( 737) 334 80.2 6.9e-15 CCDS56516.1 EZH2 gene_id:2146|Hs108|chr7 ( 746) 334 80.2 7e-15 CCDS5891.1 EZH2 gene_id:2146|Hs108|chr7 ( 751) 334 80.2 7e-15 CCDS2749.2 SETD2 gene_id:29072|Hs108|chr3 (2564) 331 80.1 2.6e-14 CCDS1113.2 ASH1L gene_id:55870|Hs108|chr1 (2964) 321 78.1 1.3e-13 CCDS43729.1 WHSC1L1 gene_id:54904|Hs108|chr8 (1437) 316 76.7 1.6e-13 CCDS4413.1 NSD1 gene_id:64324|Hs108|chr5 (2427) 316 76.9 2.3e-13 CCDS4412.1 NSD1 gene_id:64324|Hs108|chr5 (2696) 316 77.0 2.5e-13 CCDS33940.1 WHSC1 gene_id:7468|Hs108|chr4 (1365) 301 73.5 1.4e-12 >>CCDS14304.1 SUV39H1 gene_id:6839|Hs108|chrX (412 aa) initn: 2894 init1: 2894 opt: 2894 Z-score: 3306.6 bits: 620.8 E(32554): 7.4e-178 Smith-Waterman score: 2894; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412) 10 20 30 40 50 60 pF1KB6 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF 370 380 390 400 410 >>CCDS65252.1 SUV39H1 gene_id:6839|Hs108|chrX (423 aa) initn: 2870 init1: 2870 opt: 2870 Z-score: 3279.1 bits: 615.7 E(32554): 2.5e-176 Smith-Waterman score: 2870; 99.0% identity (99.5% similar) in 412 aa overlap (1-412:12-423) 10 20 30 40 pF1KB6 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLC .:. : ::::::::::::::::::::::::::::::::::::::::::: CCDS65 MVGMSRLRNDRLADPLTGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 DYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 DYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRH 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 LDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 LDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 EGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 EGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 YDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 YDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQI 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB6 YDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 YDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK 370 380 390 400 410 420 410 pF1KB6 YLF ::: CCDS65 YLF >>CCDS53494.1 SUV39H2 gene_id:79723|Hs108|chr10 (410 aa) initn: 1620 init1: 925 opt: 1590 Z-score: 1817.9 bits: 345.3 E(32554): 6.1e-95 Smith-Waterman score: 1658; 59.3% identity (78.0% similar) in 410 aa overlap (8-411:13-409) 10 20 30 40 50 pF1KB6 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIR : : : : . ::.::: ::.: ..::.:::: ..::::::::: .. CCDS53 MAAVGAEARGAWC-VPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVVK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 EQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLR-RHHRSKTPRH----L ..:::::::.:.::: .:::: ::::: .:.:: .: . : . .. .. ::. : CCDS53 DMEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 DPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGE :..:.:.:.::::: ::.::..::: ...: : : ::: :::.::: : :::::. . CCDS53 KPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAP 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 GITL-NQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCG ::.: :... :: : ::.. :::. . .::: . :... : :::::::::.:: CCDS53 GISLVNEATFGCSCTDCFFQK---CCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 YDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQI :::::.:::: .:.::::::..::::::.:: ::.. :::::::::.:::::::::::. CCDS53 PDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQF 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 YDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF :: .: :::::::: : .::::: :::.::::::::::::::.:::::::: ::::::. CCDS53 YDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIAL 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK :.:::: :::::::::.:. :. : .: . :. ::::: ::::. .:: CCDS53 FSTRTINAGEELTFDYQMK-GSGDISSDSIDHS------PA--KKRVRTVCKCGAVTCRG 360 370 380 390 400 410 pF1KB6 YLF :: CCDS53 YLN 410 >>CCDS7104.1 SUV39H2 gene_id:79723|Hs108|chr10 (350 aa) initn: 1429 init1: 925 opt: 1398 Z-score: 1599.6 bits: 304.7 E(32554): 8.9e-83 Smith-Waterman score: 1466; 60.0% identity (78.3% similar) in 360 aa overlap (58-411:2-349) 30 40 50 60 70 80 pF1KB6 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK :::::::.:.::: .:::: ::::: .:. CCDS71 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ 10 20 30 90 100 110 120 130 140 pF1KB6 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL :: .: . : . .. .. ::. : :..:.:.:.::::: ::.::..::: ...: CCDS71 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH : : ::: :::.::: : :::::. . ::.: :... :: : ::.. :::. . CCDS71 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV 100 110 120 130 140 210 220 230 240 250 260 pF1KB6 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL .::: . :... : :::::::::.:: :::::.:::: .:.::::::..::::::.:: CCDS71 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL 150 160 170 180 190 200 270 280 290 300 310 320 pF1KB6 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF ::.. :::::::::.:::::::::::.:: .: :::::::: : .::::: :::.::: CCDS71 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF 210 220 230 240 250 260 330 340 350 360 370 380 pF1KB6 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS :::::::::::.:::::::: ::::::.:.:::: :::::::::.:. . :. : .: CCDS71 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH 270 280 290 300 310 320 390 400 410 pF1KB6 NFGLAGLPGSPKKRVRIECKCGTESCRKYLF . :. ::::: ::::. .:: :: CCDS71 S------PA--KKRVRTVCKCGAVTCRGYLN 330 340 350 >>CCDS53493.1 SUV39H2 gene_id:79723|Hs108|chr10 (230 aa) initn: 971 init1: 504 opt: 530 Z-score: 611.0 bits: 121.2 E(32554): 1e-27 Smith-Waterman score: 614; 36.4% identity (45.0% similar) in 404 aa overlap (8-411:13-229) 10 20 30 40 50 pF1KB6 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIR : : : : . ::.::: ::.: ..::.:::: ..::::::::: .. CCDS53 MAAVGAEARGAWC-VPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVVK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 EQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLA ..:::::::.:.::: .:::: ::::: .:.:: .: .: CCDS53 DMEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSND---------------KH------ 60 70 80 90 120 130 140 150 160 170 pF1KB6 NYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLN ::: : CCDS53 NYLSQ------------------------------------------------------- 100 180 190 200 210 220 230 pF1KB6 QVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNR CCDS53 ------------------------------------------------------------ 240 250 260 270 280 290 pF1KB6 VVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGA .:::::::::::.:: .: CCDS53 -----------------------------------------VITSEEAERRGQFYDNKGI 110 120 300 310 320 330 340 350 pF1KB6 TYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTI :::::::: : .::::: :::.::::::::::::::.:::::::: ::::::.:.:::: CCDS53 TYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTI 130 140 150 160 170 180 360 370 380 390 400 410 pF1KB6 RAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF :::::::::.:. :. : .: . :. ::::: ::::. .:: :: CCDS53 NAGEELTFDYQMK-GSGDISSDSIDHS------PA--KKRVRTVCKCGAVTCRGYLN 190 200 210 220 230 >>CCDS7050.2 EHMT1 gene_id:79813|Hs108|chr9 (1298 aa) initn: 589 init1: 255 opt: 537 Z-score: 609.3 bits: 123.4 E(32554): 1.3e-27 Smith-Waterman score: 537; 41.2% identity (64.6% similar) in 226 aa overlap (149-365:1027-1242) 120 130 140 150 160 170 pF1KB6 VQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVA : :: . : . :... : ..... CCDS70 DSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNI 1000 1010 1020 1030 1040 1050 180 190 200 210 220 230 pF1KB6 VG---CEC-QDCLWAPTGGCCPGASLHKFAYNDQGQV--RLRAGLP--IYECNSRCRCGY . : : .:: ...: : . :. .:.. .. . : :.::: : : CCDS70 THLQYCVCIDDC---SSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWR 1060 1070 1080 1090 1100 1110 240 250 260 270 280 290 pF1KB6 DCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIY .: :::::.:.: : ..:: : :::::.:. : ..:: :::::.:.. ::. : . CCDS70 NCRNRVVQNGLRARLQLYRTRD-MGWGVRSLQDIPPGTFVCEYVGELISDSEADVREE-- 1120 1130 1140 1150 1160 1170 300 310 320 330 340 pF1KB6 DRQGATYLFDLDYVE-DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF : .:::::: . .:: .:: .:::.:.:.:: :.::: ::. . : :.::::: CCDS70 D----SYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAF 1180 1190 1200 1210 1220 350 360 370 380 390 400 pF1KB6 FATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK :.:: :.:::.: ::: CCDS70 FSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHSSAALAQRQASAAQEAQEDGL 1230 1240 1250 1260 1270 1280 >>CCDS4726.1 EHMT2 gene_id:10919|Hs108|chr6 (1176 aa) initn: 555 init1: 262 opt: 531 Z-score: 603.0 bits: 122.0 E(32554): 2.9e-27 Smith-Waterman score: 535; 37.7% identity (59.7% similar) in 273 aa overlap (149-408:905-1142) 120 130 140 150 160 170 pF1KB6 VQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINE------YRVGEGI : :: . :. . ::.: . . ..: CCDS47 LGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNI 880 890 900 910 920 930 180 190 200 210 220 pF1KB6 TLNQVAVGCEC-QDCLWAPTGGCCPGASLHKFAYNDQGQV-----RLRAGLPIYECNSRC : : : : .:: ...: : . :. .:.. ... : :.:::. : CCDS47 THLQ---HCTCVDDC---SSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPL-IFECNQAC 940 950 960 970 980 230 240 250 260 270 280 pF1KB6 RCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERR : .: :::::.::. : ..:: :::::.:. : ...:. :::::.:.. ::. : CCDS47 SCWRNCKNRVVQSGIKVRLQLYRTAK-MGWGVRALQTIPQGTFICEYVGELISDAEADVR 990 1000 1010 1020 1030 1040 290 300 310 320 330 340 pF1KB6 GQIYDRQGATYLFDLDYVE-DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLP . .:::::: . .:: .:: ::::::.:.:: ::::. ::. . : :.: CCDS47 ------EDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFP 1050 1060 1070 1080 1090 1100 350 360 370 380 390 400 pF1KB6 RIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTE :::::..: ::.:::: :::. . :..: . :.::.: CCDS47 RIAFFSSRDIRTGEELGFDYGDRF--WDIKSKYFT-------------------CQCGSE 1110 1120 1130 410 pF1KB6 SCRKYLF .:. CCDS47 KCKHSAEAIALEQSRLARLDPHPELLPELGSLPPVNT 1140 1150 1160 1170 >>CCDS4725.1 EHMT2 gene_id:10919|Hs108|chr6 (1210 aa) initn: 519 init1: 262 opt: 531 Z-score: 602.9 bits: 122.1 E(32554): 2.9e-27 Smith-Waterman score: 535; 37.7% identity (59.7% similar) in 273 aa overlap (149-408:939-1176) 120 130 140 150 160 170 pF1KB6 VQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINE------YRVGEGI : :: . :. . ::.: . . ..: CCDS47 LGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNI 910 920 930 940 950 960 180 190 200 210 220 pF1KB6 TLNQVAVGCEC-QDCLWAPTGGCCPGASLHKFAYNDQGQV-----RLRAGLPIYECNSRC : : : : .:: ...: : . :. .:.. ... : :.:::. : CCDS47 THLQ---HCTCVDDC---SSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPL-IFECNQAC 970 980 990 1000 1010 1020 230 240 250 260 270 280 pF1KB6 RCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERR : .: :::::.::. : ..:: :::::.:. : ...:. :::::.:.. ::. : CCDS47 SCWRNCKNRVVQSGIKVRLQLYRTAK-MGWGVRALQTIPQGTFICEYVGELISDAEADVR 1030 1040 1050 1060 1070 1080 290 300 310 320 330 340 pF1KB6 GQIYDRQGATYLFDLDYVE-DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLP . .:::::: . .:: .:: ::::::.:.:: ::::. ::. . : :.: CCDS47 ------EDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFP 1090 1100 1110 1120 1130 350 360 370 380 390 400 pF1KB6 RIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTE :::::..: ::.:::: :::. . :..: . :.::.: CCDS47 RIAFFSSRDIRTGEELGFDYGDRF--WDIKSKYFT-------------------CQCGSE 1140 1150 1160 1170 410 pF1KB6 SCRKYLF .:. CCDS47 KCKHSAEAIALEQSRLARLDPHPELLPELGSLPPVNT 1180 1190 1200 1210 >>CCDS75425.1 EHMT2 gene_id:10919|Hs108|chr6 (1233 aa) initn: 555 init1: 262 opt: 531 Z-score: 602.7 bits: 122.1 E(32554): 3e-27 Smith-Waterman score: 535; 37.7% identity (59.7% similar) in 273 aa overlap (149-408:962-1199) 120 130 140 150 160 170 pF1KB6 VQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINE------YRVGEGI : :: . :. . ::.: . . ..: CCDS75 LGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNI 940 950 960 970 980 990 180 190 200 210 220 pF1KB6 TLNQVAVGCEC-QDCLWAPTGGCCPGASLHKFAYNDQGQV-----RLRAGLPIYECNSRC : : : : .:: ...: : . :. .:.. ... : :.:::. : CCDS75 THLQ---HCTCVDDC---SSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPL-IFECNQAC 1000 1010 1020 1030 1040 230 240 250 260 270 280 pF1KB6 RCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERR : .: :::::.::. : ..:: :::::.:. : ...:. :::::.:.. ::. : CCDS75 SCWRNCKNRVVQSGIKVRLQLYRTAK-MGWGVRALQTIPQGTFICEYVGELISDAEADVR 1050 1060 1070 1080 1090 1100 290 300 310 320 330 340 pF1KB6 GQIYDRQGATYLFDLDYVE-DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLP . .:::::: . .:: .:: ::::::.:.:: ::::. ::. . : :.: CCDS75 ------EDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFP 1110 1120 1130 1140 1150 350 360 370 380 390 400 pF1KB6 RIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTE :::::..: ::.:::: :::. . :..: . :.::.: CCDS75 RIAFFSSRDIRTGEELGFDYGDRF--WDIKSKYFT-------------------CQCGSE 1160 1170 1180 1190 410 pF1KB6 SCRKYLF .:. CCDS75 KCKHSAEAIALEQSRLARLDPHPELLPELGSLPPVNT 1200 1210 1220 1230 >>CCDS63528.1 SETMAR gene_id:6419|Hs108|chr3 (365 aa) initn: 442 init1: 147 opt: 467 Z-score: 536.5 bits: 108.0 E(32554): 1.5e-23 Smith-Waterman score: 497; 34.7% identity (59.1% similar) in 274 aa overlap (157-411:48-298) 130 140 150 160 170 180 pF1KB6 ALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAV---GCEC : : : .. :: : .. . . :: : CCDS63 KEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVGPGADIDPTQITFPGCIC 20 30 40 50 60 70 190 200 210 220 230 pF1KB6 --QDCLWAPTGGCCPGASLHKFAYNDQGQVR-LRAG----LPIYECNSRCRCGYDCPNRV :: : : : : :.:.. .: . .: :..::: :::. : ::: CCDS63 VKTPCL--P--GTCSCLR-HGENYDDNSCLRDIGSGGKYAEPVFECNVLCRCSDHCRNRV 80 90 100 110 120 130 240 250 260 270 280 290 pF1KB6 VQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGAT ::::... . .:.: .:::.:::: : :. :: ::.::.. :..:: .. .. .. CCDS63 VQKGLQFHFQVFKTHK-KGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSN 140 150 160 170 180 190 300 310 320 330 340 pF1KB6 YLFDLDYVEDVYT-------VDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAF :.. . : ::. :: .: :::..:.::::.::: . : ::.. .:..:. CCDS63 YIIAIR--EHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM---VPKLAL 200 210 220 230 240 350 360 370 380 390 400 pF1KB6 FATRTIRAGEELTFDYNMQVD--PVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESC ::.. : :::..::. . :. .. :.: . ..: : ::..:: CCDS63 FAAKDIVPEEELSYDYSGRYLNLTVSEDKERLDHG------------KLRKPCYCGAKSC 250 260 270 280 290 410 pF1KB6 RKYLF .: CCDS63 TAFLPFDSSLYCPVEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLEVSLFSDKQLAPPYS 300 310 320 330 340 350 412 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:04:59 2016 done: Sat Nov 5 11:05:00 2016 Total Scan time: 2.450 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]