FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6619, 412 aa 1>>>pF1KB6619 412 - 412 aa - 412 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4405+/-0.000407; mu= 16.9664+/- 0.025 mean_var=73.1285+/-14.778, 0's: 0 Z-trim(111.2): 35 B-trim: 0 in 0/53 Lambda= 0.149979 statistics sampled from 19766 (19777) to 19766 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.596), E-opt: 0.2 (0.232), width: 16 Scan time: 7.240 The best scores are: opt bits E(85289) NP_446464 (OMIM: 215700,603470) argininosuccinate ( 412) 2735 601.3 1.4e-171 NP_000041 (OMIM: 215700,603470) argininosuccinate ( 412) 2735 601.3 1.4e-171 XP_005272257 (OMIM: 215700,603470) PREDICTED: argi ( 412) 2735 601.3 1.4e-171 XP_016870218 (OMIM: 215700,603470) PREDICTED: argi ( 444) 2735 601.4 1.5e-171 XP_011517007 (OMIM: 215700,603470) PREDICTED: argi ( 450) 2735 601.4 1.5e-171 >>NP_446464 (OMIM: 215700,603470) argininosuccinate synt (412 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 3201.5 bits: 601.3 E(85289): 1.4e-171 Smith-Waterman score: 2735; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412) 10 20 30 40 50 60 pF1KB6 MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_446 MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_446 IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_446 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_446 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_446 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_446 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_446 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK 370 380 390 400 410 >>NP_000041 (OMIM: 215700,603470) argininosuccinate synt (412 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 3201.5 bits: 601.3 E(85289): 1.4e-171 Smith-Waterman score: 2735; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412) 10 20 30 40 50 60 pF1KB6 MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK 370 380 390 400 410 >>XP_005272257 (OMIM: 215700,603470) PREDICTED: arginino (412 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 3201.5 bits: 601.3 E(85289): 1.4e-171 Smith-Waterman score: 2735; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412) 10 20 30 40 50 60 pF1KB6 MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK 370 380 390 400 410 >>XP_016870218 (OMIM: 215700,603470) PREDICTED: arginino (444 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 3201.0 bits: 601.4 E(85289): 1.5e-171 Smith-Waterman score: 2735; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:33-444) 10 20 30 pF1KB6 MSSKGSVVLAYSGGLDTSCILVWLKEQGYD :::::::::::::::::::::::::::::: XP_016 KRLAPDSRVVHCTVKTDSRRRELTPPIPDAMSSKGSVVLAYSGGLDTSCILVWLKEQGYD 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 VIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSSALYEDRYLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSSALYEDRYLLG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 TSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCYSLAPQIKVIAPWRMPEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCYSLAPQIKVIAPWRMPEF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 YNRFKGRNDLMEYAKQHGIPIPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNRFKGRNDLMEYAKQHGIPIPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKT 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 QDPAKAPNTPDILEIEFKKGVPVKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDPAKAPNTPDILEIEFKKGVPVKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVE 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 NRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 CEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPLSLYNEELVSMNVQGDYEPTDATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPLSLYNEELVSMNVQGDYEPTDATG 370 380 390 400 410 420 400 410 pF1KB6 FININSLRLKEYHRLQSKVTAK :::::::::::::::::::::: XP_016 FININSLRLKEYHRLQSKVTAK 430 440 >>XP_011517007 (OMIM: 215700,603470) PREDICTED: arginino (450 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 3201.0 bits: 601.4 E(85289): 1.5e-171 Smith-Waterman score: 2735; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:39-450) 10 20 30 pF1KB6 MSSKGSVVLAYSGGLDTSCILVWLKEQGYD :::::::::::::::::::::::::::::: XP_011 GTPALFLRVVHCTVKTDSRRRELTPPIPDAMSSKGSVVLAYSGGLDTSCILVWLKEQGYD 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 VIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSSALYEDRYLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSSALYEDRYLLG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 TSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCYSLAPQIKVIAPWRMPEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCYSLAPQIKVIAPWRMPEF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 YNRFKGRNDLMEYAKQHGIPIPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNRFKGRNDLMEYAKQHGIPIPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKT 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 QDPAKAPNTPDILEIEFKKGVPVKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDPAKAPNTPDILEIEFKKGVPVKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVE 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 NRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 CEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPLSLYNEELVSMNVQGDYEPTDATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPLSLYNEELVSMNVQGDYEPTDATG 370 380 390 400 410 420 400 410 pF1KB6 FININSLRLKEYHRLQSKVTAK :::::::::::::::::::::: XP_011 FININSLRLKEYHRLQSKVTAK 430 440 450 412 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:08:14 2016 done: Sat Nov 5 11:08:15 2016 Total Scan time: 7.240 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]