FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6622, 436 aa 1>>>pF1KB6622 436 - 436 aa - 436 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2147+/-0.00116; mu= 12.8423+/- 0.069 mean_var=72.3090+/-14.176, 0's: 0 Z-trim(101.9): 30 B-trim: 2 in 1/49 Lambda= 0.150827 statistics sampled from 6719 (6725) to 6719 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.562), E-opt: 0.2 (0.207), width: 16 Scan time: 2.190 The best scores are: opt bits E(32554) CCDS2187.1 ORC4 gene_id:5000|Hs108|chr2 ( 436) 2829 625.2 3.8e-179 CCDS54405.1 ORC4 gene_id:5000|Hs108|chr2 ( 362) 2348 520.5 1e-147 CCDS54404.1 ORC4 gene_id:5000|Hs108|chr2 ( 352) 2293 508.6 4e-144 >>CCDS2187.1 ORC4 gene_id:5000|Hs108|chr2 (436 aa) initn: 2829 init1: 2829 opt: 2829 Z-score: 3329.7 bits: 625.2 E(32554): 3.8e-179 Smith-Waterman score: 2829; 99.8% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB6 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: CCDS21 NSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN 370 380 390 400 410 420 430 pF1KB6 CPTDVRQWATSSLSWL :::::::::::::::: CCDS21 CPTDVRQWATSSLSWL 430 >>CCDS54405.1 ORC4 gene_id:5000|Hs108|chr2 (362 aa) initn: 2348 init1: 2348 opt: 2348 Z-score: 2765.4 bits: 520.5 E(32554): 1e-147 Smith-Waterman score: 2348; 99.7% identity (100.0% similar) in 362 aa overlap (75-436:1-362) 50 60 70 80 90 100 pF1KB6 KHLSELLKRTALHGESNSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQ :::.:::::::::::::::::::::::::: CCDS54 MLINHALKELMEIEEVSENVLQVHLNGLLQ 10 20 30 110 120 130 140 150 160 pF1KB6 INDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 INDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLF 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 AHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFP 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 QYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 QYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLM 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 LALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPF 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB6 NFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKL 280 290 300 310 320 330 410 420 430 pF1KB6 LLDNTQIMNALQKYPNCPTDVRQWATSSLSWL :::::::::::::::::::::::::::::::: CCDS54 LLDNTQIMNALQKYPNCPTDVRQWATSSLSWL 340 350 360 >>CCDS54404.1 ORC4 gene_id:5000|Hs108|chr2 (352 aa) initn: 2293 init1: 2293 opt: 2293 Z-score: 2700.9 bits: 508.6 E(32554): 4e-144 Smith-Waterman score: 2293; 100.0% identity (100.0% similar) in 352 aa overlap (85-436:1-352) 60 70 80 90 100 110 pF1KB6 ALHGESNSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEI :::::::::::::::::::::::::::::: CCDS54 MEIEEVSENVLQVHLNGLLQINDKIALKEI 10 20 30 120 130 140 150 160 170 pF1KB6 TRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLY 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB6 NLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB6 SLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASH 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB6 PFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQ 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB6 KFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNA 280 290 300 310 320 330 420 430 pF1KB6 LQKYPNCPTDVRQWATSSLSWL :::::::::::::::::::::: CCDS54 LQKYPNCPTDVRQWATSSLSWL 340 350 436 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:47:36 2016 done: Sat Nov 5 18:47:36 2016 Total Scan time: 2.190 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]