FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6622, 436 aa 1>>>pF1KB6622 436 - 436 aa - 436 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7729+/-0.000501; mu= 15.7313+/- 0.031 mean_var=80.5129+/-16.627, 0's: 0 Z-trim(109.2): 27 B-trim: 434 in 2/48 Lambda= 0.142936 statistics sampled from 17326 (17344) to 17326 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.547), E-opt: 0.2 (0.203), width: 16 Scan time: 8.570 The best scores are: opt bits E(85289) XP_016859715 (OMIM: 603056,613800) PREDICTED: orig ( 436) 2829 593.6 3.4e-169 XP_011509557 (OMIM: 603056,613800) PREDICTED: orig ( 436) 2829 593.6 3.4e-169 NP_859525 (OMIM: 603056,613800) origin recognition ( 436) 2829 593.6 3.4e-169 NP_002543 (OMIM: 603056,613800) origin recognition ( 436) 2829 593.6 3.4e-169 NP_859526 (OMIM: 603056,613800) origin recognition ( 436) 2829 593.6 3.4e-169 NP_001177808 (OMIM: 603056,613800) origin recognit ( 436) 2829 593.6 3.4e-169 NP_001177811 (OMIM: 603056,613800) origin recognit ( 362) 2348 494.3 2.1e-139 NP_001177810 (OMIM: 603056,613800) origin recognit ( 352) 2293 483.0 5.3e-136 XP_016859716 (OMIM: 603056,613800) PREDICTED: orig ( 352) 2293 483.0 5.3e-136 XP_011539829 (OMIM: 224690,601902) PREDICTED: orig ( 501) 164 44.0 0.001 XP_016856878 (OMIM: 224690,601902) PREDICTED: orig ( 615) 164 44.1 0.0012 NP_001177748 (OMIM: 224690,601902) origin recognit ( 856) 164 44.2 0.0016 NP_004144 (OMIM: 224690,601902) origin recognition ( 861) 164 44.2 0.0016 NP_001177747 (OMIM: 224690,601902) origin recognit ( 861) 164 44.2 0.0016 >>XP_016859715 (OMIM: 603056,613800) PREDICTED: origin r (436 aa) initn: 2829 init1: 2829 opt: 2829 Z-score: 3158.6 bits: 593.6 E(85289): 3.4e-169 Smith-Waterman score: 2829; 99.8% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB6 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: XP_016 NSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN 370 380 390 400 410 420 430 pF1KB6 CPTDVRQWATSSLSWL :::::::::::::::: XP_016 CPTDVRQWATSSLSWL 430 >>XP_011509557 (OMIM: 603056,613800) PREDICTED: origin r (436 aa) initn: 2829 init1: 2829 opt: 2829 Z-score: 3158.6 bits: 593.6 E(85289): 3.4e-169 Smith-Waterman score: 2829; 99.8% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB6 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: XP_011 NSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN 370 380 390 400 410 420 430 pF1KB6 CPTDVRQWATSSLSWL :::::::::::::::: XP_011 CPTDVRQWATSSLSWL 430 >>NP_859525 (OMIM: 603056,613800) origin recognition com (436 aa) initn: 2829 init1: 2829 opt: 2829 Z-score: 3158.6 bits: 593.6 E(85289): 3.4e-169 Smith-Waterman score: 2829; 99.8% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB6 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_859 NSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN 370 380 390 400 410 420 430 pF1KB6 CPTDVRQWATSSLSWL :::::::::::::::: NP_859 CPTDVRQWATSSLSWL 430 >>NP_002543 (OMIM: 603056,613800) origin recognition com (436 aa) initn: 2829 init1: 2829 opt: 2829 Z-score: 3158.6 bits: 593.6 E(85289): 3.4e-169 Smith-Waterman score: 2829; 99.8% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB6 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_002 NSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN 370 380 390 400 410 420 430 pF1KB6 CPTDVRQWATSSLSWL :::::::::::::::: NP_002 CPTDVRQWATSSLSWL 430 >>NP_859526 (OMIM: 603056,613800) origin recognition com (436 aa) initn: 2829 init1: 2829 opt: 2829 Z-score: 3158.6 bits: 593.6 E(85289): 3.4e-169 Smith-Waterman score: 2829; 99.8% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB6 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_859 NSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_859 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN 370 380 390 400 410 420 430 pF1KB6 CPTDVRQWATSSLSWL :::::::::::::::: NP_859 CPTDVRQWATSSLSWL 430 >>NP_001177808 (OMIM: 603056,613800) origin recognition (436 aa) initn: 2829 init1: 2829 opt: 2829 Z-score: 3158.6 bits: 593.6 E(85289): 3.4e-169 Smith-Waterman score: 2829; 99.8% identity (100.0% similar) in 436 aa overlap (1-436:1-436) 10 20 30 40 50 60 pF1KB6 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_001 NSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN 370 380 390 400 410 420 430 pF1KB6 CPTDVRQWATSSLSWL :::::::::::::::: NP_001 CPTDVRQWATSSLSWL 430 >>NP_001177811 (OMIM: 603056,613800) origin recognition (362 aa) initn: 2348 init1: 2348 opt: 2348 Z-score: 2623.8 bits: 494.3 E(85289): 2.1e-139 Smith-Waterman score: 2348; 99.7% identity (100.0% similar) in 362 aa overlap (75-436:1-362) 50 60 70 80 90 100 pF1KB6 KHLSELLKRTALHGESNSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQ :::.:::::::::::::::::::::::::: NP_001 MLINHALKELMEIEEVSENVLQVHLNGLLQ 10 20 30 110 120 130 140 150 160 pF1KB6 INDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLF 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 AHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFP 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 QYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLM 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 LALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPF 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB6 NFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKL 280 290 300 310 320 330 410 420 430 pF1KB6 LLDNTQIMNALQKYPNCPTDVRQWATSSLSWL :::::::::::::::::::::::::::::::: NP_001 LLDNTQIMNALQKYPNCPTDVRQWATSSLSWL 340 350 360 >>NP_001177810 (OMIM: 603056,613800) origin recognition (352 aa) initn: 2293 init1: 2293 opt: 2293 Z-score: 2562.6 bits: 483.0 E(85289): 5.3e-136 Smith-Waterman score: 2293; 100.0% identity (100.0% similar) in 352 aa overlap (85-436:1-352) 60 70 80 90 100 110 pF1KB6 ALHGESNSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEI :::::::::::::::::::::::::::::: NP_001 MEIEEVSENVLQVHLNGLLQINDKIALKEI 10 20 30 120 130 140 150 160 170 pF1KB6 TRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLY 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB6 NLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB6 SLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASH 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB6 PFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQ 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB6 KFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNA 280 290 300 310 320 330 420 430 pF1KB6 LQKYPNCPTDVRQWATSSLSWL :::::::::::::::::::::: NP_001 LQKYPNCPTDVRQWATSSLSWL 340 350 >>XP_016859716 (OMIM: 603056,613800) PREDICTED: origin r (352 aa) initn: 2293 init1: 2293 opt: 2293 Z-score: 2562.6 bits: 483.0 E(85289): 5.3e-136 Smith-Waterman score: 2293; 100.0% identity (100.0% similar) in 352 aa overlap (85-436:1-352) 60 70 80 90 100 110 pF1KB6 ALHGESNSVLIIGPRGSGKTMLISHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEI :::::::::::::::::::::::::::::: XP_016 MEIEEVSENVLQVHLNGLLQINDKIALKEI 10 20 30 120 130 140 150 160 170 pF1KB6 TRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLY 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB6 NLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB6 SLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLPAEFPDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASH 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB6 PFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQ 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB6 KFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNA 280 290 300 310 320 330 420 430 pF1KB6 LQKYPNCPTDVRQWATSSLSWL :::::::::::::::::::::: XP_016 LQKYPNCPTDVRQWATSSLSWL 340 350 >>XP_011539829 (OMIM: 224690,601902) PREDICTED: origin r (501 aa) initn: 50 init1: 50 opt: 164 Z-score: 187.7 bits: 44.0 E(85289): 0.001 Smith-Waterman score: 174; 21.3% identity (57.1% similar) in 352 aa overlap (7-352:115-441) 10 20 30 pF1KB6 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSN .: :: : : ... : :. .. . XP_011 SSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEA-RLRLHVSAVPES 90 100 110 120 130 140 40 50 60 70 80 90 pF1KB6 LFGVQVQYKHLSELLKRTALHGESNSVLIIGPRGSGKTMLISHALKELMEIEEVSE--NV : . ... . .... : .. . : : :.::: . .... :.. .... XP_011 LPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPF 150 160 170 180 190 200 100 110 120 130 140 150 pF1KB6 LQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPV ...::. .... ... :. :....:.:. .. : .: . . .:. . . XP_011 QYIEVNGM-KLTEP---HQVYVQI-LQKLTGQKATANHAAEL-LAKQFCTRGSPQET--T 210 220 230 240 250 160 170 180 190 200 210 pF1KB6 IFILDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILE-LLEKRVKSRFSHR ....::.::. :: : ..::::: .. ..:.... .:. : .. .::.::.. XP_011 VLLVDELDLLWTHK-QDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLT 260 270 280 290 300 310 220 230 240 250 260 270 pF1KB6 QIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSED-RSVQEVLQKHFNI .. .. . . : .:.. .:. : : .. . ..: :: : : .. .. .: XP_011 RM-CFQPYTYSQLQQILRSRLKHLKAFEDDAI-QLVARKVAALSGDARRCLDICRRATEI 320 330 340 350 360 370 280 290 300 310 320 330 pF1KB6 SKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLEICLIIAM . . . . . :: .: : ::: : .: : . ... :::: .. :. XP_011 CE----FSQQKPDSPGLVTIAHS-MEAVDEMFSS------SYITAIKNSSVLEQSFLRAI 380 390 400 410 420 340 350 360 370 380 390 pF1KB6 KHLNDIYEE--EPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMER : .. . : .::..:.. XP_011 --LAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRN 430 440 450 460 470 436 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:47:36 2016 done: Sat Nov 5 18:47:37 2016 Total Scan time: 8.570 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]