FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6623, 413 aa 1>>>pF1KB6623 413 - 413 aa - 413 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3783+/-0.000491; mu= 0.5538+/- 0.031 mean_var=311.1574+/-63.260, 0's: 0 Z-trim(117.6): 9 B-trim: 347 in 1/54 Lambda= 0.072708 statistics sampled from 29804 (29813) to 29804 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.35), width: 16 Scan time: 7.260 The best scores are: opt bits E(85289) NP_055856 (OMIM: 616787) clusterin-associated prot ( 413) 2654 292.1 1.7e-78 XP_016878558 (OMIM: 616787) PREDICTED: clusterin-a ( 440) 2606 287.1 5.7e-77 XP_016878561 (OMIM: 616787) PREDICTED: clusterin-a ( 402) 2581 284.5 3.3e-76 NP_001317383 (OMIM: 616787) clusterin-associated p ( 432) 2330 258.2 2.9e-68 XP_016878557 (OMIM: 616787) PREDICTED: clusterin-a ( 459) 2282 253.2 1e-66 XP_016878560 (OMIM: 616787) PREDICTED: clusterin-a ( 421) 2257 250.5 5.8e-66 XP_006720930 (OMIM: 616787) PREDICTED: clusterin-a ( 341) 2165 240.8 4e-63 XP_016878562 (OMIM: 616787) PREDICTED: clusterin-a ( 360) 1841 206.8 7.1e-53 NP_079069 (OMIM: 616787) clusterin-associated prot ( 247) 1595 180.8 3.2e-45 >>NP_055856 (OMIM: 616787) clusterin-associated protein (413 aa) initn: 2654 init1: 2654 opt: 2654 Z-score: 1530.4 bits: 292.1 E(85289): 1.7e-78 Smith-Waterman score: 2654; 100.0% identity (100.0% similar) in 413 aa overlap (1-413:1-413) 10 20 30 40 50 60 pF1KB6 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 SDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF 370 380 390 400 410 >>XP_016878558 (OMIM: 616787) PREDICTED: clusterin-assoc (440 aa) initn: 2606 init1: 2606 opt: 2606 Z-score: 1502.9 bits: 287.1 E(85289): 5.7e-77 Smith-Waterman score: 2606; 99.5% identity (99.8% similar) in 408 aa overlap (6-413:33-440) 10 20 30 pF1KB6 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLV : .::::::::::::::::::::::::::: XP_016 RGQNPGGSPWSLWLGSGHIKQTALANWRVLLSDFTEMMRALGYPRHISMENFRTPNFGLV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 SEVLLWLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEVLLWLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 ELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 DLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 KIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLED 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 HHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPK 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 PQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTK 370 380 390 400 410 420 400 410 pF1KB6 PNRRVRKSEPLDESDNDF :::::::::::::::::: XP_016 PNRRVRKSEPLDESDNDF 430 440 >>XP_016878561 (OMIM: 616787) PREDICTED: clusterin-assoc (402 aa) initn: 2581 init1: 2581 opt: 2581 Z-score: 1489.2 bits: 284.5 E(85289): 3.3e-76 Smith-Waterman score: 2581; 100.0% identity (100.0% similar) in 402 aa overlap (12-413:1-402) 10 20 30 40 50 60 pF1KB6 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ 10 20 30 40 70 80 90 100 110 120 pF1KB6 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB6 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD 290 300 310 320 330 340 370 380 390 400 410 pF1KB6 SDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF 350 360 370 380 390 400 >>NP_001317383 (OMIM: 616787) clusterin-associated prote (432 aa) initn: 2399 init1: 2329 opt: 2330 Z-score: 1346.5 bits: 258.2 E(85289): 2.9e-68 Smith-Waterman score: 2606; 95.6% identity (95.6% similar) in 432 aa overlap (1-413:1-432) 10 20 30 40 50 60 pF1KB6 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD 310 320 330 340 350 360 370 380 390 400 pF1KB6 SDDN-------------------EDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVR :::: ::::::::::::::::::::::::::::::::::::: NP_001 SDDNMEAAPALLGKCKTSSSKKQEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVR 370 380 390 400 410 420 410 pF1KB6 KSEPLDESDNDF :::::::::::: NP_001 KSEPLDESDNDF 430 >>XP_016878557 (OMIM: 616787) PREDICTED: clusterin-assoc (459 aa) initn: 2345 init1: 2275 opt: 2282 Z-score: 1319.0 bits: 253.2 E(85289): 1e-66 Smith-Waterman score: 2558; 95.1% identity (95.3% similar) in 427 aa overlap (6-413:33-459) 10 20 30 pF1KB6 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLV : .::::::::::::::::::::::::::: XP_016 RGQNPGGSPWSLWLGSGHIKQTALANWRVLLSDFTEMMRALGYPRHISMENFRTPNFGLV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 SEVLLWLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEVLLWLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 ELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLY 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 DLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 KIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLED 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 HHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPK 310 320 330 340 350 360 340 350 360 370 pF1KB6 PQTAMEMLMQGRPGKRIVGTMQGGDSDDN-------------------EDSEESEIDMED ::::::::::::::::::::::::::::: :::::::::::: XP_016 PQTAMEMLMQGRPGKRIVGTMQGGDSDDNMEAAPALLGKCKTSSSKKQEDSEESEIDMED 370 380 390 400 410 420 380 390 400 410 pF1KB6 DDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF ::::::::::::::::::::::::::::::::::::: XP_016 DDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF 430 440 450 >>XP_016878560 (OMIM: 616787) PREDICTED: clusterin-assoc (421 aa) initn: 2326 init1: 2256 opt: 2257 Z-score: 1305.3 bits: 250.5 E(85289): 5.8e-66 Smith-Waterman score: 2533; 95.5% identity (95.5% similar) in 421 aa overlap (12-413:1-421) 10 20 30 40 50 60 pF1KB6 MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQ 10 20 30 40 70 80 90 100 110 120 pF1KB6 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINE 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKE 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB6 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGD 290 300 310 320 330 340 370 380 390 400 pF1KB6 SDDN-------------------EDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVR :::: ::::::::::::::::::::::::::::::::::::: XP_016 SDDNMEAAPALLGKCKTSSSKKQEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVR 350 360 370 380 390 400 410 pF1KB6 KSEPLDESDNDF :::::::::::: XP_016 KSEPLDESDNDF 410 420 >>XP_006720930 (OMIM: 616787) PREDICTED: clusterin-assoc (341 aa) initn: 2165 init1: 2165 opt: 2165 Z-score: 1254.2 bits: 240.8 E(85289): 4e-63 Smith-Waterman score: 2165; 100.0% identity (100.0% similar) in 341 aa overlap (73-413:1-341) 50 60 70 80 90 100 pF1KB6 VKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITS :::::::::::::::::::::::::::::: XP_006 MATKAHIKLNTKKLYQADGYAVKELLKITS 10 20 30 110 120 130 140 150 160 pF1KB6 VLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEV 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 ELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 ELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 RFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEM 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB6 LMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRK 280 290 300 310 320 330 410 pF1KB6 SEPLDESDNDF ::::::::::: XP_006 SEPLDESDNDF 340 >>XP_016878562 (OMIM: 616787) PREDICTED: clusterin-assoc (360 aa) initn: 1910 init1: 1840 opt: 1841 Z-score: 1070.3 bits: 206.8 E(85289): 7.1e-53 Smith-Waterman score: 2117; 94.7% identity (94.7% similar) in 360 aa overlap (73-413:1-360) 50 60 70 80 90 100 pF1KB6 VKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITS :::::::::::::::::::::::::::::: XP_016 MATKAHIKLNTKKLYQADGYAVKELLKITS 10 20 30 110 120 130 140 150 160 pF1KB6 VLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEV 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 ELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 ELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQE 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 RFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEM 220 230 240 250 260 270 350 360 370 380 pF1KB6 LMQGRPGKRIVGTMQGGDSDDN-------------------EDSEESEIDMEDDDDEDDD :::::::::::::::::::::: ::::::::::::::::::: XP_016 LMQGRPGKRIVGTMQGGDSDDNMEAAPALLGKCKTSSSKKQEDSEESEIDMEDDDDEDDD 280 290 300 310 320 330 390 400 410 pF1KB6 LEDESISLSPTKPNRRVRKSEPLDESDNDF :::::::::::::::::::::::::::::: XP_016 LEDESISLSPTKPNRRVRKSEPLDESDNDF 340 350 360 >>NP_079069 (OMIM: 616787) clusterin-associated protein (247 aa) initn: 1595 init1: 1595 opt: 1595 Z-score: 932.8 bits: 180.8 E(85289): 3.2e-45 Smith-Waterman score: 1595; 100.0% identity (100.0% similar) in 247 aa overlap (167-413:1-247) 140 150 160 170 180 190 pF1KB6 LKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQV :::::::::::::::::::::::::::::: NP_079 MRTEAIARPLEINETEKVMRIAIKEILTQV 10 20 30 200 210 220 230 240 250 pF1KB6 QKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 QKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQY 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB6 DTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 DTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDI 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB6 DIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 DIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMED 160 170 180 190 200 210 380 390 400 410 pF1KB6 DDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF ::::::::::::::::::::::::::::::::::::: NP_079 DDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF 220 230 240 413 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:09:21 2016 done: Sat Nov 5 11:09:22 2016 Total Scan time: 7.260 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]