FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6625, 406 aa 1>>>pF1KB6625 406 - 406 aa - 406 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1624+/-0.000762; mu= 13.7918+/- 0.046 mean_var=96.7462+/-19.384, 0's: 0 Z-trim(111.4): 61 B-trim: 15 in 1/49 Lambda= 0.130394 statistics sampled from 12296 (12358) to 12296 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.38), width: 16 Scan time: 3.060 The best scores are: opt bits E(32554) CCDS13515.1 ARFGAP1 gene_id:55738|Hs108|chr20 ( 406) 2800 536.7 1.4e-152 CCDS13516.1 ARFGAP1 gene_id:55738|Hs108|chr20 ( 414) 2521 484.3 9.2e-137 CCDS63327.1 ARFGAP1 gene_id:55738|Hs108|chr20 ( 361) 2111 407.1 1.4e-113 CCDS63326.1 ARFGAP1 gene_id:55738|Hs108|chr20 ( 403) 1897 366.9 1.9e-101 CCDS63328.1 ARFGAP1 gene_id:55738|Hs108|chr20 ( 293) 1794 347.4 1e-95 CCDS14042.1 ARFGAP3 gene_id:26286|Hs108|chr22 ( 516) 424 89.8 6.2e-18 CCDS7926.1 ARFGAP2 gene_id:84364|Hs108|chr11 ( 521) 379 81.4 2.2e-15 CCDS73283.1 ARFGAP2 gene_id:84364|Hs108|chr11 ( 493) 376 80.8 3.1e-15 CCDS46722.1 ARFGAP3 gene_id:26286|Hs108|chr22 ( 472) 316 69.5 7.5e-12 >>CCDS13515.1 ARFGAP1 gene_id:55738|Hs108|chr20 (406 aa) initn: 2800 init1: 2800 opt: 2800 Z-score: 2852.6 bits: 536.7 E(32554): 1.4e-152 Smith-Waterman score: 2800; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406) 10 20 30 40 50 60 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS 310 320 330 340 350 360 370 380 390 400 pF1KB6 SDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW :::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 370 380 390 400 >>CCDS13516.1 ARFGAP1 gene_id:55738|Hs108|chr20 (414 aa) initn: 2536 init1: 1651 opt: 2521 Z-score: 2568.8 bits: 484.3 E(32554): 9.2e-137 Smith-Waterman score: 2744; 97.1% identity (97.1% similar) in 416 aa overlap (1-406:1-414) 10 20 30 40 50 60 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 ---------ASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDV ::::::::::::::::::::::::::::::::::::::: :::::::::: CCDS13 WGHKQQPEPASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASK--GVGSKGWRDV 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT 300 310 320 330 340 350 360 370 380 390 400 pF1KB6 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 360 370 380 390 400 410 >>CCDS63327.1 ARFGAP1 gene_id:55738|Hs108|chr20 (361 aa) initn: 2126 init1: 1241 opt: 2111 Z-score: 2152.8 bits: 407.1 E(32554): 1.4e-113 Smith-Waterman score: 2334; 96.4% identity (96.7% similar) in 360 aa overlap (57-406:4-361) 30 40 50 60 70 80 pF1KB6 AFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREF .::::::::::::::::::::::::::::: CCDS63 MRTTFVRSVTMDKWKDIELEKMKAGGNAKFREF 10 20 30 90 100 110 120 130 140 pF1KB6 LESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMV 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 HRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 HRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSS 100 110 120 130 140 150 210 220 230 240 250 pF1KB6 LYSGWSSFTTGASRFASAAKEGATKFGSQASQK----------ASELGHSLNENVLKPAQ ::::::::::::::::::::::::::::::::: ::::::::::::::::: CCDS63 LYSGWSSFTTGASRFASAAKEGATKFGSQASQKFWGHKQQPEPASELGHSLNENVLKPAQ 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 EKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGL :::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: CCDS63 EKVKEGKIFDDVSSGVSQLASK--GVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGL 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB6 DHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNS 280 290 300 310 320 330 380 390 400 pF1KB6 NSDGGEGGEGTKKAVPPAVPTDDGWDNQNW :::::::::::::::::::::::::::::: CCDS63 NSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 340 350 360 >>CCDS63326.1 ARFGAP1 gene_id:55738|Hs108|chr20 (403 aa) initn: 1929 init1: 1897 opt: 1897 Z-score: 1934.6 bits: 366.9 E(32554): 1.9e-101 Smith-Waterman score: 1897; 99.6% identity (99.6% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG :::::::::::::::::::::::::::::::::::::: : CCDS63 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKCQRRLCCHQSHCSAGHLGRAFC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS CCDS63 PVSWHEALCGQTGREEQASLLPPKHVVGALEVCARGCPRCHVPHTPGTAAEWPGRLCLSR 310 320 330 340 350 360 >>CCDS63328.1 ARFGAP1 gene_id:55738|Hs108|chr20 (293 aa) initn: 1775 init1: 1775 opt: 1794 Z-score: 1831.9 bits: 347.4 E(32554): 1e-95 Smith-Waterman score: 1794; 93.3% identity (96.1% similar) in 285 aa overlap (122-406:11-293) 100 110 120 130 140 150 pF1KB6 DYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMVHRVSG :. .. ..: . : .:: ::. :::: CCDS63 MLSSESSWSLRRITILAGPCRRSTTAEPR--PSLGIRVSG 10 20 30 160 170 180 190 200 210 pF1KB6 QPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 QPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGW 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB6 SSFTTGASRFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGKIFDDVSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SSFTTGASRFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGKIFDDVSSG 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB6 VSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWET 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB6 FGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 FGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAV 220 230 240 250 260 270 400 pF1KB6 PPAVPTDDGWDNQNW ::::::::::::::: CCDS63 PPAVPTDDGWDNQNW 280 290 >>CCDS14042.1 ARFGAP3 gene_id:26286|Hs108|chr22 (516 aa) initn: 368 init1: 250 opt: 424 Z-score: 435.5 bits: 89.8 E(32554): 6.2e-18 Smith-Waterman score: 442; 30.3% identity (57.2% similar) in 409 aa overlap (1-371:1-375) 10 20 30 40 50 pF1KB6 MASPRTRKVL---KEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLS :..: . .: :..: :.:::.::: ::.:.:.:::...:..::: ::.:::::: CCDS14 MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 FVRSVTMDK-WKDIELEKMKAGGNAKFREFLESQEDYDPCWS--LQEKYNSRAAALFRDK :.::. .:. :. ..:. :..::::. :.... : . . ::::::: :.:.: CCDS14 FIRSTELDSNWSWFQLRCMQVGGNASASSFFHQH----GCSTNDTNAKYNSRAAQLYREK 70 80 90 100 110 120 130 140 150 pF1KB6 VVALA------EGREWSLESSPAQNWTPPQPRTLPSMVHRVS------------GQPQSV . .:: .: . :.: . .:: :. .. .:: ..:.:. CCDS14 IKSLASQATRKHGTDLWLDSCVVPPLSPP-PKEEDFFASHVSPEVSDTAWASAIAEPSSL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 TASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTT :. . : :... :. . :: :. :.: : .::. . CCDS14 TS---RPVETTLENNEGGQE--QGPSVEGL-NVPTKATLE-------VSSIIK------- 180 190 200 210 220 230 240 250 260 pF1KB6 GASRFASAAKEG-ATKFGSQASQKASELGHSLNENVLKPAQ--EKVKE----GKIFDDVS . . ::.: ..: :: ..:: :... ... : :: .:.:: .:. . CCDS14 ---KKPNQAKKGLGAKKGSLGAQK---LANTCFNEIEKQAQAADKMKEQEDLAKVVSKEE 220 230 240 250 260 270 280 290 300 310 320 pF1KB6 SGVSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQN--SGLDHFQNSNIDQS : ::.: . . . .: .::: . .:: : .. : : ..: .:... CCDS14 SIVSSLRLAYKDLEIQMKKDEKMNISGKKN--VDSDRLGMGFGNCRSVISHSVTSDMQTI 270 280 290 300 310 320 330 340 350 360 370 380 pF1KB6 FWETFGSAEPTKTRKSPSSDSWTCADTS-----TERRSSDSWEVWGSASTNRNSNSDGGE :. :.: : .. :.::. ...: .: ::: :. : ..: CCDS14 EQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSS-SFSSWDDSSDSYWKKETSKD 330 340 350 360 370 380 390 400 pF1KB6 GGEGTKKAVPPAVPTDDGWDNQNW CCDS14 TETVLKTTGYSDRPTARRKPDYEPVENTDEAQKKFGNVKAISSDMYFGRQSQADYETRAR 390 400 410 420 430 440 >>CCDS7926.1 ARFGAP2 gene_id:84364|Hs108|chr11 (521 aa) initn: 334 init1: 250 opt: 379 Z-score: 389.7 bits: 81.4 E(32554): 2.2e-15 Smith-Waterman score: 386; 30.8% identity (64.3% similar) in 263 aa overlap (9-266:13-261) 10 20 30 40 50 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHL ..:..:. :..::.::: ::.:.:.:::...:..::: ::.::::: CCDS79 MAAEPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SFVRSVTMDK-WKDIELEKMKAGGNAKFREFLESQEDYDPCWS--LQEKYNSRAAALFRD ::.::. .:. :. ..:. :..::::. :.... : . . ::::::: ..:. CCDS79 SFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQH----GCTANDANTKYNSRAAQMYRE 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 KVVALAEGREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLG :. :. . .: .. : . ..:. . . . . .. :.. .. : CCDS79 KIRQLGSA---ALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPPAWDAPATEPSG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 SYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFG . : : ... :... : . . :.:... .. ::. : .. :.: : ..: : CCDS79 TQQPAPSTESSGLAQ--PEHGPNTDLLGTSPKASLELKSSII-GKKKPAAAKKGLGAKKG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 SQASQKASELGHSLNENVLKPAQ--EKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVT : ::.: ..:..: . . :: ::..: . : CCDS79 LGA-QKVS--SQSFSE-IERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRK 240 250 260 270 280 300 310 320 330 340 350 pF1KB6 TFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTC CCDS79 KEEKKLQNLEGKKREQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFD 290 300 310 320 330 340 >>CCDS73283.1 ARFGAP2 gene_id:84364|Hs108|chr11 (493 aa) initn: 334 init1: 250 opt: 376 Z-score: 387.0 bits: 80.8 E(32554): 3.1e-15 Smith-Waterman score: 387; 28.8% identity (56.5% similar) in 416 aa overlap (9-398:13-406) 10 20 30 40 50 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHL ..:..:. :..::.::: ::.:.:.:::...:..::: ::.::::: CCDS73 MAAEPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SFVRSVTMDK-WKDIELEKMKAGGNAKFREFLESQEDYDPCWS--LQEKYNSRAAALFRD ::.::. .:. :. ..:. :..::::. :.... : . . ::::::: ..:. CCDS73 SFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQH----GCTANDANTKYNSRAAQMYRE 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 KVVALAEGREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAF-EDWLNDDL :. :. . ..: : : : :: .. :: : :: : : : :: CCDS73 KIRQLGSAALARHGTDPPA-WDAPA--TEPSGTQ----QPAPSTESSGLAQPEHGPNTDL 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 -GSYQGAQGN-RYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGAT :. :. . . .:. : :. ...... . .::. : :..:.. CCDS73 LGTSPKASLELKSSIIGKKKPAAAKKGLGAKKGLGAQKVSSQSFSE-IERQAQVAEKLRE 170 180 190 200 210 220 240 250 260 270 280 pF1KB6 KFGSQASQKASE-LGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRD . ...:...: : . :. . .. :: : .... . . : .. :.: . . CCDS73 QQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERL-GMGLVSRSS 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 VT-TFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSS-- :. . .: ..: ..: . : :: :.. . ::.:. : : . .: : CCDS73 VSHSVLSEMQVIEQETPVSAKS-SRSQLDLFDDVG-------TFASGPP-KYKDNPFSLG 290 300 310 320 330 350 360 370 380 390 pF1KB6 ----DSW-TCADTSTERRSSDSWEVWGSA-------STNR---NSNSDGGEGGEGTKK-A . : : : . .: :: :. .::: .: :.: :..:. .: : CCDS73 ESFGSRWDTDAAWGMDRVEEKEPEVTISSIRPISERATNRREVESRSSGLESSEARQKFA 340 350 360 370 380 390 400 pF1KB6 VPPAVPTDDGWDNQNW :. .: CCDS73 GAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSLGNVLPT 400 410 420 430 440 450 >>CCDS46722.1 ARFGAP3 gene_id:26286|Hs108|chr22 (472 aa) initn: 304 init1: 250 opt: 316 Z-score: 326.2 bits: 69.5 E(32554): 7.5e-12 Smith-Waterman score: 343; 28.3% identity (53.2% similar) in 389 aa overlap (1-371:1-331) 10 20 30 40 50 pF1KB6 MASPRTRKVL---KEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLS :..: . .: :..: :.:::.::: ::.:.:.:::...:..::: ::.:::::: CCDS46 MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 FVRSVTMDK-WKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVV :.::. .:. :. ..:. :..:::: : : : . . .: ..: CCDS46 FIRSTELDSNWSWFQLRCMQVGGNA-------SALWLDSCVVPPLSPPPKEEDFFASHVS 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ALAEGREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQ . :. :. :. :.:.:. . : :... :. . CCDS46 PEVSDTAWA--SAIAE--------------------PSSLTS---RPVETTLENNEGGQE 120 130 140 180 190 200 210 220 230 pF1KB6 GAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEG-ATKFGSQ :: :. :.: : .::. . . . ::.: ..: :: CCDS46 --QGPSVEGL-NVPTKATLE-------VSSIIK----------KKPNQAKKGLGAKKGSL 150 160 170 180 240 250 260 270 280 pF1KB6 ASQKASELGHSLNENVLKPAQ--EKVKE----GKIFDDVSSGVSQLASKVQGVGSKGWRD ..:: :... ... : :: .:.:: .:. . : ::.: . . . .: CCDS46 GAQK---LANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKD 190 200 210 220 230 240 290 300 310 320 330 340 pF1KB6 VTTFFSGKAEGPLDSPSEGHSYQN--SGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSD .::: . .:: : .. : : ..: .:... :. :.: : .. :.: CCDS46 EKMNISGKKN--VDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDD 250 260 270 280 290 300 350 360 370 380 390 400 pF1KB6 SWTCADTS-----TERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWD :. ...: .: ::: :. : ..: CCDS46 SYFTSSSSYFDEPVELRSS-SFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKP 310 320 330 340 350 360 406 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:35:33 2016 done: Sat Nov 5 11:35:33 2016 Total Scan time: 3.060 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]