FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6625, 406 aa 1>>>pF1KB6625 406 - 406 aa - 406 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0390+/-0.000321; mu= 14.3265+/- 0.020 mean_var=99.4661+/-19.816, 0's: 0 Z-trim(118.7): 151 B-trim: 90 in 1/50 Lambda= 0.128599 statistics sampled from 31690 (31846) to 31690 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.373), width: 16 Scan time: 8.560 The best scores are: opt bits E(85289) NP_060679 (OMIM: 608377) ADP-ribosylation factor G ( 406) 2800 529.7 5e-150 XP_006723886 (OMIM: 608377) PREDICTED: ADP-ribosyl ( 404) 2774 524.9 1.4e-148 NP_783202 (OMIM: 608377) ADP-ribosylation factor G ( 414) 2521 477.9 1.9e-134 NP_001268412 (OMIM: 608377) ADP-ribosylation facto ( 361) 2111 401.8 1.4e-111 NP_001268411 (OMIM: 608377) ADP-ribosylation facto ( 403) 1897 362.1 1.3e-99 NP_001268413 (OMIM: 608377) ADP-ribosylation facto ( 293) 1794 342.9 5.9e-94 XP_011527203 (OMIM: 608377) PREDICTED: ADP-ribosyl ( 416) 1673 320.6 4.5e-87 XP_016883439 (OMIM: 608377) PREDICTED: ADP-ribosyl ( 416) 1673 320.6 4.5e-87 XP_005261582 (OMIM: 612439) PREDICTED: ADP-ribosyl ( 472) 424 88.9 2.8e-17 NP_055385 (OMIM: 612439) ADP-ribosylation factor G ( 516) 424 88.9 3e-17 NP_115765 (OMIM: 606908) ADP-ribosylation factor G ( 521) 379 80.6 9.9e-15 NP_001229761 (OMIM: 606908) ADP-ribosylation facto ( 493) 376 80.0 1.4e-14 XP_005253225 (OMIM: 606908) PREDICTED: ADP-ribosyl ( 535) 369 78.7 3.7e-14 XP_011518707 (OMIM: 606908) PREDICTED: ADP-ribosyl ( 507) 364 77.8 6.7e-14 XP_016873902 (OMIM: 606908) PREDICTED: ADP-ribosyl ( 535) 351 75.4 3.7e-13 XP_006718409 (OMIM: 606908) PREDICTED: ADP-ribosyl ( 546) 349 75.0 4.9e-13 XP_005253224 (OMIM: 606908) PREDICTED: ADP-ribosyl ( 549) 349 75.0 4.9e-13 XP_005253223 (OMIM: 606908) PREDICTED: ADP-ribosyl ( 560) 349 75.1 5e-13 NP_001135765 (OMIM: 612439) ADP-ribosylation facto ( 472) 316 68.9 3e-11 NP_073570 (OMIM: 616916) stromal membrane-associat ( 429) 252 57.0 1.1e-07 XP_011508711 (OMIM: 603817) PREDICTED: arf-GAP wit ( 891) 254 57.6 1.4e-07 XP_011508710 (OMIM: 603817) PREDICTED: arf-GAP wit ( 959) 254 57.6 1.5e-07 NP_001128663 (OMIM: 603817) arf-GAP with SH3 domai ( 961) 254 57.6 1.5e-07 XP_006711965 (OMIM: 603817) PREDICTED: arf-GAP wit ( 964) 254 57.6 1.5e-07 XP_006711964 (OMIM: 603817) PREDICTED: arf-GAP wit ( 970) 254 57.6 1.5e-07 XP_011508709 (OMIM: 603817) PREDICTED: arf-GAP wit ( 975) 254 57.6 1.5e-07 XP_011508708 (OMIM: 603817) PREDICTED: arf-GAP wit ( 978) 254 57.6 1.5e-07 XP_011508707 (OMIM: 603817) PREDICTED: arf-GAP wit ( 995) 254 57.6 1.6e-07 NP_003878 (OMIM: 603817) arf-GAP with SH3 domain, (1006) 254 57.6 1.6e-07 XP_006711961 (OMIM: 603817) PREDICTED: arf-GAP wit (1009) 254 57.6 1.6e-07 XP_011508706 (OMIM: 603817) PREDICTED: arf-GAP wit (1017) 254 57.6 1.6e-07 XP_011508705 (OMIM: 603817) PREDICTED: arf-GAP wit (1020) 254 57.6 1.6e-07 NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778) 252 57.2 1.7e-07 XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP wit ( 785) 252 57.2 1.7e-07 XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP wit ( 806) 252 57.2 1.7e-07 XP_016861537 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 252 57.2 1.7e-07 XP_005248817 (OMIM: 611372) PREDICTED: stromal mem ( 250) 243 55.1 2.2e-07 XP_011534349 (OMIM: 611372) PREDICTED: stromal mem ( 429) 243 55.3 3.4e-07 NP_001268368 (OMIM: 611372) stromal membrane-assoc ( 436) 243 55.3 3.4e-07 NP_068759 (OMIM: 611372) stromal membrane-associat ( 440) 243 55.3 3.4e-07 XP_011534347 (OMIM: 611372) PREDICTED: stromal mem ( 456) 243 55.3 3.5e-07 NP_001037770 (OMIM: 611372) stromal membrane-assoc ( 467) 243 55.3 3.6e-07 NP_006860 (OMIM: 608114) arf-GAP with dual PH doma ( 374) 239 54.5 5e-07 XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 243 55.5 5.3e-07 XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 243 55.5 5.3e-07 XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 243 55.5 5.3e-07 XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 243 55.5 5.5e-07 XP_011510904 (OMIM: 607766) PREDICTED: arf-GAP wit ( 820) 243 55.5 5.5e-07 XP_016861536 (OMIM: 607766) PREDICTED: arf-GAP wit ( 841) 243 55.5 5.7e-07 XP_016861535 (OMIM: 607766) PREDICTED: arf-GAP wit ( 848) 243 55.5 5.7e-07 >>NP_060679 (OMIM: 608377) ADP-ribosylation factor GTPas (406 aa) initn: 2800 init1: 2800 opt: 2800 Z-score: 2814.5 bits: 529.7 E(85289): 5e-150 Smith-Waterman score: 2800; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406) 10 20 30 40 50 60 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS 310 320 330 340 350 360 370 380 390 400 pF1KB6 SDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW :::::::::::::::::::::::::::::::::::::::::::::: NP_060 SDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 370 380 390 400 >>XP_006723886 (OMIM: 608377) PREDICTED: ADP-ribosylatio (404 aa) initn: 1924 init1: 1892 opt: 2774 Z-score: 2788.4 bits: 524.9 E(85289): 1.4e-148 Smith-Waterman score: 2774; 99.5% identity (99.5% similar) in 406 aa overlap (1-406:1-404) 10 20 30 40 50 60 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG :::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: XP_006 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASK--GVGSKGWRDVTTFFSGKAEG 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS 300 310 320 330 340 350 370 380 390 400 pF1KB6 SDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW :::::::::::::::::::::::::::::::::::::::::::::: XP_006 SDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 360 370 380 390 400 >>NP_783202 (OMIM: 608377) ADP-ribosylation factor GTPas (414 aa) initn: 2536 init1: 1651 opt: 2521 Z-score: 2534.6 bits: 477.9 E(85289): 1.9e-134 Smith-Waterman score: 2744; 97.1% identity (97.1% similar) in 416 aa overlap (1-406:1-414) 10 20 30 40 50 60 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_783 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_783 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_783 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_783 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 ---------ASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDV ::::::::::::::::::::::::::::::::::::::: :::::::::: NP_783 WGHKQQPEPASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASK--GVGSKGWRDV 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_783 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT 300 310 320 330 340 350 360 370 380 390 400 pF1KB6 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_783 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 360 370 380 390 400 410 >>NP_001268412 (OMIM: 608377) ADP-ribosylation factor GT (361 aa) initn: 2126 init1: 1241 opt: 2111 Z-score: 2124.3 bits: 401.8 E(85289): 1.4e-111 Smith-Waterman score: 2334; 96.4% identity (96.7% similar) in 360 aa overlap (57-406:4-361) 30 40 50 60 70 80 pF1KB6 AFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREF .::::::::::::::::::::::::::::: NP_001 MRTTFVRSVTMDKWKDIELEKMKAGGNAKFREF 10 20 30 90 100 110 120 130 140 pF1KB6 LESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMV 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 HRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSS 100 110 120 130 140 150 210 220 230 240 250 pF1KB6 LYSGWSSFTTGASRFASAAKEGATKFGSQASQK----------ASELGHSLNENVLKPAQ ::::::::::::::::::::::::::::::::: ::::::::::::::::: NP_001 LYSGWSSFTTGASRFASAAKEGATKFGSQASQKFWGHKQQPEPASELGHSLNENVLKPAQ 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 EKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGL :::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: NP_001 EKVKEGKIFDDVSSGVSQLASK--GVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGL 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB6 DHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNS 280 290 300 310 320 330 380 390 400 pF1KB6 NSDGGEGGEGTKKAVPPAVPTDDGWDNQNW :::::::::::::::::::::::::::::: NP_001 NSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 340 350 360 >>NP_001268411 (OMIM: 608377) ADP-ribosylation factor GT (403 aa) initn: 1929 init1: 1897 opt: 1897 Z-score: 1909.1 bits: 362.1 E(85289): 1.3e-99 Smith-Waterman score: 1897; 99.6% identity (99.6% similar) in 280 aa overlap (1-280:1-280) 10 20 30 40 50 60 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG :::::::::::::::::::::::::::::::::::::: : NP_001 SELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKCQRRLCCHQSHCSAGHLGRAFC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTSTERRS NP_001 PVSWHEALCGQTGREEQASLLPPKHVVGALEVCARGCPRCHVPHTPGTAAEWPGRLCLSR 310 320 330 340 350 360 >>NP_001268413 (OMIM: 608377) ADP-ribosylation factor GT (293 aa) initn: 1775 init1: 1775 opt: 1794 Z-score: 1807.7 bits: 342.9 E(85289): 5.9e-94 Smith-Waterman score: 1794; 93.3% identity (96.1% similar) in 285 aa overlap (122-406:11-293) 100 110 120 130 140 150 pF1KB6 DYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMVHRVSG :. .. ..: . : .:: ::. :::: NP_001 MLSSESSWSLRRITILAGPCRRSTTAEPR--PSLGIRVSG 10 20 30 160 170 180 190 200 210 pF1KB6 QPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGW 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB6 SSFTTGASRFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGKIFDDVSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSFTTGASRFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGKIFDDVSSG 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB6 VSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWET 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB6 FGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGSAEPTKTRKSPSSDSWTCADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAV 220 230 240 250 260 270 400 pF1KB6 PPAVPTDDGWDNQNW ::::::::::::::: NP_001 PPAVPTDDGWDNQNW 280 290 >>XP_011527203 (OMIM: 608377) PREDICTED: ADP-ribosylatio (416 aa) initn: 1683 init1: 1651 opt: 1673 Z-score: 1684.3 bits: 320.6 E(85289): 4.5e-87 Smith-Waterman score: 2770; 97.6% identity (97.6% similar) in 416 aa overlap (1-406:1-416) 10 20 30 40 50 60 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 ---------ASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDV ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WGHKQQPEPASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDV 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT 310 320 330 340 350 360 360 370 380 390 400 pF1KB6 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 370 380 390 400 410 >>XP_016883439 (OMIM: 608377) PREDICTED: ADP-ribosylatio (416 aa) initn: 1683 init1: 1651 opt: 1673 Z-score: 1684.3 bits: 320.6 E(85289): 4.5e-87 Smith-Waterman score: 2770; 97.6% identity (97.6% similar) in 416 aa overlap (1-406:1-416) 10 20 30 40 50 60 pF1KB6 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQG 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQKF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 ---------ASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDV ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGHKQQPEPASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLASKVQGVGSKGWRDV 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWT 310 320 330 340 350 360 360 370 380 390 400 pF1KB6 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEGTKKAVPPAVPTDDGWDNQNW 370 380 390 400 410 >>XP_005261582 (OMIM: 612439) PREDICTED: ADP-ribosylatio (472 aa) initn: 340 init1: 250 opt: 424 Z-score: 431.2 bits: 88.9 E(85289): 2.8e-17 Smith-Waterman score: 442; 30.6% identity (57.3% similar) in 396 aa overlap (1-362:1-363) 10 20 30 40 50 pF1KB6 MASPRTRKVL---KEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLS :..: . .: :..: :.:::.::: ::.:.:.:::...:..::: ::.:::::: XP_005 MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 FVRSVTMDK-WKDIELEKMKAGGNAKFREFLESQEDYDPCWS--LQEKYNSRAAALFRDK :.::. .:. :. ..:. :..::::. :.... : . . ::::::: :.:.: XP_005 FIRSTELDSNWSWFQLRCMQVGGNASASSFFHQH----GCSTNDTNAKYNSRAAQLYREK 70 80 90 100 110 120 130 140 150 pF1KB6 VVALA------EGREWSLESSPAQNWTPPQPRTLPSMVHRVS------------GQPQSV . .:: .: . :.: . .:: :. .. .:: ..:.:. XP_005 IKSLASQATRKHGTDLWLDSCVVPPLSPP-PKEEDFFASHVSPEVSDTAWASAIAEPSSL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 TASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTT :. . : :... :. . :: :. :.: : .::. . XP_005 TS---RPVETTLENNEGGQE--QGPSVEGL-NVPTKATLE-------VSSIIK------- 180 190 200 210 220 230 240 250 260 pF1KB6 GASRFASAAKEG-ATKFGSQASQKASELGHSLNENVLKPAQ--EKVKE----GKIFDDVS . . ::.: ..: :: ..:: :... ... : :: .:.:: .:. . XP_005 ---KKPNQAKKGLGAKKGSLGAQK---LANTCFNEIEKQAQAADKMKEQEDLAKVVSKEE 220 230 240 250 260 270 280 290 300 310 320 pF1KB6 SGVSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQN--SGLDHFQNSNIDQS : ::.: . . . .: .::: . .:: : .. : : ..: .:... XP_005 SIVSSLRLAYKDLEIQMKKDEKMNISGKKN--VDSDRLGMGFGNCRSVISHSVTSDMQTI 270 280 290 300 310 320 330 340 350 360 370 380 pF1KB6 FWETFGSAEPTKTRKSPSSDSW-TCADTSTERRSSDSWEVWGSASTNRNSNSDGGEGGEG :. :.: : .. :.::. : .. : ::. : XP_005 EQESPIMAKPRKKYNDDSDDSYFTSSSRPTARRKPDYEPVENTDEAQKKFGNVKAISSDM 330 340 350 360 370 380 390 400 pF1KB6 TKKAVPPAVPTDDGWDNQNW XP_005 YFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQG 390 400 410 420 430 440 >>NP_055385 (OMIM: 612439) ADP-ribosylation factor GTPas (516 aa) initn: 368 init1: 250 opt: 424 Z-score: 430.6 bits: 88.9 E(85289): 3e-17 Smith-Waterman score: 442; 30.3% identity (57.2% similar) in 409 aa overlap (1-371:1-375) 10 20 30 40 50 pF1KB6 MASPRTRKVL---KEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLS :..: . .: :..: :.:::.::: ::.:.:.:::...:..::: ::.:::::: NP_055 MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 FVRSVTMDK-WKDIELEKMKAGGNAKFREFLESQEDYDPCWS--LQEKYNSRAAALFRDK :.::. .:. :. ..:. :..::::. :.... : . . ::::::: :.:.: NP_055 FIRSTELDSNWSWFQLRCMQVGGNASASSFFHQH----GCSTNDTNAKYNSRAAQLYREK 70 80 90 100 110 120 130 140 150 pF1KB6 VVALA------EGREWSLESSPAQNWTPPQPRTLPSMVHRVS------------GQPQSV . .:: .: . :.: . .:: :. .. .:: ..:.:. NP_055 IKSLASQATRKHGTDLWLDSCVVPPLSPP-PKEEDFFASHVSPEVSDTAWASAIAEPSSL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 TASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTT :. . : :... :. . :: :. :.: : .::. . NP_055 TS---RPVETTLENNEGGQE--QGPSVEGL-NVPTKATLE-------VSSIIK------- 180 190 200 210 220 230 240 250 260 pF1KB6 GASRFASAAKEG-ATKFGSQASQKASELGHSLNENVLKPAQ--EKVKE----GKIFDDVS . . ::.: ..: :: ..:: :... ... : :: .:.:: .:. . NP_055 ---KKPNQAKKGLGAKKGSLGAQK---LANTCFNEIEKQAQAADKMKEQEDLAKVVSKEE 220 230 240 250 260 270 280 290 300 310 320 pF1KB6 SGVSQLASKVQGVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQN--SGLDHFQNSNIDQS : ::.: . . . .: .::: . .:: : .. : : ..: .:... NP_055 SIVSSLRLAYKDLEIQMKKDEKMNISGKKN--VDSDRLGMGFGNCRSVISHSVTSDMQTI 270 280 290 300 310 320 330 340 350 360 370 380 pF1KB6 FWETFGSAEPTKTRKSPSSDSWTCADTS-----TERRSSDSWEVWGSASTNRNSNSDGGE :. :.: : .. :.::. ...: .: ::: :. : ..: NP_055 EQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSS-SFSSWDDSSDSYWKKETSKD 330 340 350 360 370 380 390 400 pF1KB6 GGEGTKKAVPPAVPTDDGWDNQNW NP_055 TETVLKTTGYSDRPTARRKPDYEPVENTDEAQKKFGNVKAISSDMYFGRQSQADYETRAR 390 400 410 420 430 440 406 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:35:33 2016 done: Sat Nov 5 11:35:35 2016 Total Scan time: 8.560 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]