Result of FASTA (omim) for
pF1KB6626
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6626, 439 aa
1>>>pF1KB6626 439 - 439 aa - 439 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5067+/-0.000347; mu= 7.2882+/- 0.022
mean_var=127.2210+/-25.518, 0's: 0 Z-trim(118.2): 457 B-trim: 0 in 0/55
Lambda= 0.113709
statistics sampled from 30528 (31003) to 30528 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.364), width: 16
Scan time: 9.800
The best scores are: opt bits E(85289)
XP_011518397 (OMIM: 602732) PREDICTED: rho GTPase- ( 439) 2928 491.5 1.8e-138
NP_004299 (OMIM: 602732) rho GTPase-activating pro ( 439) 2928 491.5 1.8e-138
XP_016873209 (OMIM: 602732) PREDICTED: rho GTPase- ( 395) 1899 322.7 1.1e-87
NP_851852 (OMIM: 609405) rho GTPase-activating pro ( 433) 1510 258.9 1.9e-68
NP_001185655 (OMIM: 609405) rho GTPase-activating ( 305) 1248 215.8 1.2e-55
NP_001017526 (OMIM: 609405) rho GTPase-activating ( 464) 1066 186.0 1.7e-46
NP_001307604 (OMIM: 603292) BCL2/adenovirus E1B 19 ( 376) 400 76.7 1.1e-13
NP_004321 (OMIM: 603292) BCL2/adenovirus E1B 19 kD ( 435) 400 76.8 1.3e-13
XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 399 76.7 1.9e-13
XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 399 76.7 1.9e-13
XP_011538309 (OMIM: 610585) PREDICTED: rho GTPase- ( 637) 399 76.7 2e-13
NP_001242953 (OMIM: 610585) rho GTPase-activating ( 714) 399 76.7 2.2e-13
XP_011538305 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 399 76.7 2.2e-13
XP_011538304 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 399 76.7 2.2e-13
NP_001307603 (OMIM: 603292) BCL2/adenovirus E1B 19 ( 447) 393 75.6 2.9e-13
XP_016863113 (OMIM: 613299) PREDICTED: protein FAM ( 981) 390 75.3 7.8e-13
XP_011529819 (OMIM: 613299) PREDICTED: protein FAM ( 995) 390 75.3 7.9e-13
XP_005262740 (OMIM: 613299) PREDICTED: protein FAM ( 995) 390 75.3 7.9e-13
XP_005262739 (OMIM: 613299) PREDICTED: protein FAM (1003) 390 75.3 8e-13
XP_005262738 (OMIM: 613299) PREDICTED: protein FAM (1009) 390 75.3 8e-13
NP_055698 (OMIM: 613299) protein FAM13A isoform a (1023) 390 75.3 8.1e-13
XP_011529818 (OMIM: 613299) PREDICTED: protein FAM (1023) 390 75.3 8.1e-13
XP_016871959 (OMIM: 610585) PREDICTED: rho GTPase- ( 655) 383 74.1 1.2e-12
XP_011538308 (OMIM: 610585) PREDICTED: rho GTPase- ( 661) 383 74.1 1.2e-12
XP_016871961 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 380 73.5 1.5e-12
XP_011538314 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 380 73.5 1.5e-12
XP_016871960 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 380 73.5 1.5e-12
NP_001242955 (OMIM: 610585) rho GTPase-activating ( 608) 379 73.4 1.8e-12
NP_067049 (OMIM: 610585) rho GTPase-activating pro ( 698) 379 73.4 2.1e-12
NP_001242954 (OMIM: 610585) rho GTPase-activating ( 704) 379 73.4 2.1e-12
XP_011538306 (OMIM: 610585) PREDICTED: rho GTPase- ( 704) 379 73.4 2.1e-12
XP_011538313 (OMIM: 610585) PREDICTED: rho GTPase- ( 565) 376 72.9 2.4e-12
XP_016869847 (OMIM: 610691) PREDICTED: protein pru ( 337) 371 72.0 2.7e-12
NP_001294978 (OMIM: 610691) protein prune homolog ( 337) 371 72.0 2.7e-12
NP_001294979 (OMIM: 610691) protein prune homolog ( 352) 371 72.0 2.8e-12
NP_001317609 (OMIM: 610691) protein prune homolog ( 353) 371 72.0 2.8e-12
XP_016869845 (OMIM: 610691) PREDICTED: protein pru ( 352) 369 71.6 3.6e-12
XP_011538317 (OMIM: 610585) PREDICTED: rho GTPase- ( 359) 364 70.8 6.4e-12
XP_016869848 (OMIM: 610691) PREDICTED: protein pru ( 336) 363 70.7 6.8e-12
XP_016869843 (OMIM: 610691) PREDICTED: protein pru ( 365) 363 70.7 7.3e-12
XP_011538315 (OMIM: 610585) PREDICTED: rho GTPase- ( 436) 364 70.9 7.6e-12
XP_016869834 (OMIM: 610691) PREDICTED: protein pru (3091) 377 73.4 9.2e-12
XP_005251802 (OMIM: 610691) PREDICTED: protein pru (3092) 377 73.4 9.2e-12
XP_005251805 (OMIM: 610691) PREDICTED: protein pru (3090) 375 73.1 1.2e-11
XP_005251803 (OMIM: 610691) PREDICTED: protein pru (3091) 375 73.1 1.2e-11
NP_001245346 (OMIM: 609568) rho GTPase-activating (1155) 367 71.6 1.2e-11
NP_001245347 (OMIM: 609568) rho GTPase-activating (1155) 367 71.6 1.2e-11
NP_001245345 (OMIM: 609568) rho GTPase-activating (1165) 367 71.6 1.2e-11
NP_001245344 (OMIM: 609568) rho GTPase-activating (1168) 367 71.6 1.2e-11
NP_065860 (OMIM: 609568) rho GTPase-activating pro (1191) 367 71.6 1.3e-11
>>XP_011518397 (OMIM: 602732) PREDICTED: rho GTPase-acti (439 aa)
initn: 2928 init1: 2928 opt: 2928 Z-score: 2606.9 bits: 491.5 E(85289): 1.8e-138
Smith-Waterman score: 2928; 100.0% identity (100.0% similar) in 439 aa overlap (1-439:1-439)
10 20 30 40 50 60
pF1KB6 MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 KFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 PEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFT
370 380 390 400 410 420
430
pF1KB6 KFLLDHQGELFPSPDPSGL
:::::::::::::::::::
XP_011 KFLLDHQGELFPSPDPSGL
430
>>NP_004299 (OMIM: 602732) rho GTPase-activating protein (439 aa)
initn: 2928 init1: 2928 opt: 2928 Z-score: 2606.9 bits: 491.5 E(85289): 1.8e-138
Smith-Waterman score: 2928; 100.0% identity (100.0% similar) in 439 aa overlap (1-439:1-439)
10 20 30 40 50 60
pF1KB6 MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 KFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 LPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 PEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFT
370 380 390 400 410 420
430
pF1KB6 KFLLDHQGELFPSPDPSGL
:::::::::::::::::::
NP_004 KFLLDHQGELFPSPDPSGL
430
>>XP_016873209 (OMIM: 602732) PREDICTED: rho GTPase-acti (395 aa)
initn: 1899 init1: 1899 opt: 1899 Z-score: 1695.3 bits: 322.7 E(85289): 1.1e-87
Smith-Waterman score: 2529; 90.0% identity (90.0% similar) in 439 aa overlap (1-439:1-395)
10 20 30 40 50 60
pF1KB6 MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDY
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGY-------------
70 80 90 100
130 140 150 160 170 180
pF1KB6 TLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISF
:::::::::::::::::::::::::::::
XP_016 -------------------------------KKNIKALYIVHPTMFIKTLLILFKPLISF
110 120 130
190 200 210 220 230 240
pF1KB6 KFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQ
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB6 QFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMG
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB6 LPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTL
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB6 PEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFT
320 330 340 350 360 370
430
pF1KB6 KFLLDHQGELFPSPDPSGL
:::::::::::::::::::
XP_016 KFLLDHQGELFPSPDPSGL
380 390
>>NP_851852 (OMIM: 609405) rho GTPase-activating protein (433 aa)
initn: 1522 init1: 1373 opt: 1510 Z-score: 1349.8 bits: 258.9 E(85289): 1.9e-68
Smith-Waterman score: 1510; 57.3% identity (84.6% similar) in 382 aa overlap (58-438:8-388)
30 40 50 60 70 80
pF1KB6 IDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIV
:. . :.::.::: :..:::::..::....
NP_851 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVT
10 20 30
90 100 110 120 130 140
pF1KB6 FSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREF
:: :::::::.:::..:: :::.:::::::.:::..:.:.::.: :::::.::..::.::
NP_851 FSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEF
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 DRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIP
:::::::.::::.:::: :::.: ..::::: :::.:..: :::::: ::.: .:: ::
NP_851 DRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 RQVLKYDDFLKSTQKSPATAP-KPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRET
.::.::. :.: ... . : : :::::::.::::::::.:..:: . : :: ::: :
NP_851 PEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKN-QGELIPPVLRFT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB6 VAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELP
:.::. ..: :::.:::::..:.:::.:. ::.: ::.::.:...:.:::::::::::::
NP_851 VTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELP
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB6 EPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNK
.:::::. : ...:. .. : :: . :.:..:::.:: :::.: .:: .: .: ::
NP_851 QPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNK
280 290 300 310 320 330
390 400 410 420 430
pF1KB6 MTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL
:...::: ::: ::.: .... .:.:. :.: ::..:... ..: .:. :
NP_851 MNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWE
340 350 360 370 380 390
NP_851 QGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL
400 410 420 430
>>NP_001185655 (OMIM: 609405) rho GTPase-activating prot (305 aa)
initn: 1260 init1: 1111 opt: 1248 Z-score: 1119.8 bits: 215.8 E(85289): 1.2e-55
Smith-Waterman score: 1248; 62.2% identity (87.5% similar) in 288 aa overlap (58-344:8-294)
30 40 50 60 70 80
pF1KB6 IDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIV
:. . :.::.::: :..:::::..::....
NP_001 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVT
10 20 30
90 100 110 120 130 140
pF1KB6 FSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREF
:: :::::::.:::..:: :::.:::::::.:::..:.:.::.: :::::.::..::.::
NP_001 FSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEF
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 DRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIP
:::::::.::::.:::: :::.: ..::::: :::.:..: :::::: ::.: .:: ::
NP_001 DRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 RQVLKYDDFLKSTQKSPATAP-KPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRET
.::.::. :.: ... . : : :::::::.::::::::.:..:: . : :: ::: :
NP_001 PEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKN-QGELIPPVLRFT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB6 VAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELP
:.::. ..: :::.:::::..:.:::.:. ::.: ::.::.:...:.:::::::::::::
NP_001 VTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELP
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB6 EPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNK
.:::::. : ...:. .
NP_001 QPLLTFQAYEQILGITCVPGEHLQQNEQL
280 290 300
>>NP_001017526 (OMIM: 609405) rho GTPase-activating prot (464 aa)
initn: 1500 init1: 917 opt: 1066 Z-score: 955.7 bits: 186.0 E(85289): 1.7e-46
Smith-Waterman score: 1438; 53.0% identity (78.2% similar) in 413 aa overlap (58-438:8-419)
30 40 50 60 70 80
pF1KB6 IDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIV
:. . :.::.::: :..:::::..::....
NP_001 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVT
10 20 30
90 100 110 120 130 140
pF1KB6 FSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREF
:: :::::::.:::..:: :::.:::::::.:::..:.:.::.: :::::.::..::.::
NP_001 FSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEF
40 50 60 70 80 90
150 160 170
pF1KB6 DRK-------------------------------YKKNIKALYIVHPTMFIKTLLILFKP
::: ::::.::::.:::: :::.: ..::
NP_001 DRKDGDLTMWPRLVSNSKLKRSSHLSLPKYWDYRYKKNLKALYVVHPTSFIKVLWNILKP
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 LISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAP-KPMPPRP
::: :::.:..: :::::: ::.: .:: :: .::.::. :.: ... . : : ::::
NP_001 LISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRP
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 PLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQ
:::.::::::::.:..:: . : :: ::: ::.::. ..: :::.:::::..:.:::.:.
NP_001 PLPTQQFGVSLQYLKDKN-QGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQR
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB6 KYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQ
::.: ::.::.:...:.:::::::::::::.:::::. : ...:. .. : :: . :
NP_001 LYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQ
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB6 VLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINP
.:..:::.:: :::.: .:: .: .: :::...::: ::: ::.: .... .:.:. :
NP_001 ILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVP
340 350 360 370 380 390
420 430
pF1KB6 INTFTKFLLDHQGELFPSPDPSGL
.: ::..:... ..: .:. :
NP_001 LNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSP
400 410 420 430 440 450
>>NP_001307604 (OMIM: 603292) BCL2/adenovirus E1B 19 kDa (376 aa)
initn: 378 init1: 334 opt: 400 Z-score: 366.6 bits: 76.7 E(85289): 1.1e-13
Smith-Waterman score: 400; 35.4% identity (60.5% similar) in 223 aa overlap (6-224:158-372)
10 20 30
pF1KB6 MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPS
: .::: :.:.. . .:: : . .
NP_001 DGSVLSDDLDESGEIDLDGLDTPSENSNEFEWEDDLPKPKTTEVIRK---GSITEYT-AA
130 140 150 160 170 180
40 50 60 70 80 90
pF1KB6 DEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPP
.: : . . . . . .: .:: . : :: . :.::..: ::
NP_001 EEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHG--GYYGDGLNA--IVVFAVCFMPE
190 200 210 220 230
100 110 120 130 140 150
pF1KB6 SHQLDHSKLLG----YLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKY
: : .. :. :. ::. : .: ..::. . : . :::.::: :...::.
NP_001 SSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRRL
240 250 260 270 280 290
160 170 180 190 200 210
pF1KB6 KKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVL
.::.:.: ::::. ::.::: . .:.:: ::.::: :: :.::.: : .: .:::. .
NP_001 RKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIK
300 310 320 330 340 350
220 230 240 250 260 270
pF1KB6 KYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQ
. :. :.. : :
NP_001 QVDQELNGKQDEPKNEQ
360 370
>>NP_004321 (OMIM: 603292) BCL2/adenovirus E1B 19 kDa pr (435 aa)
initn: 378 init1: 334 opt: 400 Z-score: 365.6 bits: 76.8 E(85289): 1.3e-13
Smith-Waterman score: 400; 35.4% identity (60.5% similar) in 223 aa overlap (6-224:217-431)
10 20 30
pF1KB6 MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPS
: .::: :.:.. . .:: : . .
NP_004 DGSVLSDDLDESGEIDLDGLDTPSENSNEFEWEDDLPKPKTTEVIRK---GSITEYT-AA
190 200 210 220 230 240
40 50 60 70 80 90
pF1KB6 DEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPP
.: : . . . . . .: .:: . : :: . :.::..: ::
NP_004 EEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHG--GYYGDGLNA--IVVFAVCFMPE
250 260 270 280 290
100 110 120 130 140 150
pF1KB6 SHQLDHSKLLG----YLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKY
: : .. :. :. ::. : .: ..::. . : . :::.::: :...::.
NP_004 SSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRRL
300 310 320 330 340 350
160 170 180 190 200 210
pF1KB6 KKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVL
.::.:.: ::::. ::.::: . .:.:: ::.::: :: :.::.: : .: .:::. .
NP_004 RKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIK
360 370 380 390 400 410
220 230 240 250 260 270
pF1KB6 KYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQ
. :. :.. : :
NP_004 QVDQELNGKQDEPKNEQ
420 430
>>XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase-acti (624 aa)
initn: 357 init1: 188 opt: 399 Z-score: 362.3 bits: 76.7 E(85289): 1.9e-13
Smith-Waterman score: 399; 30.7% identity (68.8% similar) in 215 aa overlap (230-438:70-282)
200 210 220 230 240 250
pF1KB6 KLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPP-LPNQQFGVSLQHLQEKNPEQEP
:. : :: . .:.. ...: .. .:. :
XP_011 QRDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETVHHERKYGPRLAP
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB6 IPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVIL
. .... : ... ..:: ::.:: .....::..:.... : ::. ...: : .:
XP_011 L--LVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLL
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB6 KTFLRELPEPLLTFDLYPHVVG---FLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFL
: .:::::::.. : : .. .:. ::.. . . ...::. ::..::.. ::
XP_011 KLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFL
160 170 180 190 200 210
380 390 400 410 420 430
pF1KB6 VQISAHSDQNKMTNTNLAVVFGPNLL--WAKDAAITLKAINPINTFTKFLLDHQGELFPS
...:.:. :::. :::.:::::.: ..: . ... . .. . :. ....:: .
XP_011 DEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTA
220 230 240 250 260 270
pF1KB6 PDPSGL
: : :
XP_011 PVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTG
280 290 300 310 320 330
>>XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase-acti (624 aa)
initn: 357 init1: 188 opt: 399 Z-score: 362.3 bits: 76.7 E(85289): 1.9e-13
Smith-Waterman score: 399; 30.7% identity (68.8% similar) in 215 aa overlap (230-438:70-282)
200 210 220 230 240 250
pF1KB6 KLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPP-LPNQQFGVSLQHLQEKNPEQEP
:. : :: . .:.. ...: .. .:. :
XP_005 QRDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETVHHERKYGPRLAP
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB6 IPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVIL
. .... : ... ..:: ::.:: .....::..:.... : ::. ...: : .:
XP_005 L--LVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLL
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB6 KTFLRELPEPLLTFDLYPHVVG---FLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFL
: .:::::::.. : : .. .:. ::.. . . ...::. ::..::.. ::
XP_005 KLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFL
160 170 180 190 200 210
380 390 400 410 420 430
pF1KB6 VQISAHSDQNKMTNTNLAVVFGPNLL--WAKDAAITLKAINPINTFTKFLLDHQGELFPS
...:.:. :::. :::.:::::.: ..: . ... . .. . :. ....:: .
XP_005 DEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTA
220 230 240 250 260 270
pF1KB6 PDPSGL
: : :
XP_005 PVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTG
280 290 300 310 320 330
439 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:36:05 2016 done: Sat Nov 5 11:36:06 2016
Total Scan time: 9.800 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]