FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6635, 418 aa 1>>>pF1KB6635 418 - 418 aa - 418 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9538+/-0.000827; mu= 14.8471+/- 0.050 mean_var=87.1946+/-16.836, 0's: 0 Z-trim(108.3): 40 B-trim: 0 in 0/53 Lambda= 0.137350 statistics sampled from 10062 (10096) to 10062 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.31), width: 16 Scan time: 3.040 The best scores are: opt bits E(32554) CCDS41942.1 SNX6 gene_id:58533|Hs108|chr14 ( 418) 2711 547.1 1.2e-155 CCDS9648.1 SNX6 gene_id:58533|Hs108|chr14 ( 290) 1848 376.0 2.6e-104 CCDS8113.2 SNX32 gene_id:254122|Hs108|chr11 ( 403) 1824 371.3 9.3e-103 CCDS13130.1 SNX5 gene_id:27131|Hs108|chr20 ( 404) 1772 361.0 1.2e-99 >>CCDS41942.1 SNX6 gene_id:58533|Hs108|chr14 (418 aa) initn: 2711 init1: 2711 opt: 2711 Z-score: 2908.0 bits: 547.1 E(32554): 1.2e-155 Smith-Waterman score: 2711; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB6 MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCC 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 QKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT 370 380 390 400 410 >>CCDS9648.1 SNX6 gene_id:58533|Hs108|chr14 (290 aa) initn: 1848 init1: 1848 opt: 1848 Z-score: 1986.1 bits: 376.0 E(32554): 2.6e-104 Smith-Waterman score: 1848; 100.0% identity (100.0% similar) in 290 aa overlap (129-418:1-290) 100 110 120 130 140 150 pF1KB6 AGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEV :::::::::::::::::::::::::::::: CCDS96 MTKEEFTKMKQELEAEYLAIFKKTVAMHEV 10 20 30 160 170 180 190 200 210 pF1KB6 FLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 FLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDV 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB6 DDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 DDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKF 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB6 FLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 FLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKA 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB6 LDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 LDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELK 220 230 240 250 260 270 400 410 pF1KB6 HAKGNLQLLQNCLAVLNGDT :::::::::::::::::::: CCDS96 HAKGNLQLLQNCLAVLNGDT 280 290 >>CCDS8113.2 SNX32 gene_id:254122|Hs108|chr11 (403 aa) initn: 1838 init1: 946 opt: 1824 Z-score: 1958.3 bits: 371.3 E(32554): 9.3e-103 Smith-Waterman score: 1824; 70.5% identity (91.2% similar) in 386 aa overlap (35-417:17-402) 10 20 30 40 50 60 pF1KB6 AGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHT .::::.:..:::.::::.::::::::::.: CCDS81 METYAEVGKEGKPSCASVDLQGDSSLQVEISDAVSERDKVKFTVQT 10 20 30 40 70 80 90 100 110 120 pF1KB6 KSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGE :: ::.: :.::::::::::::::::..::::.::: :::::::::::.::::::::::: CCDS81 KSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASREKLQKLGE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 GEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQD :..:.:.:::.::::::::::::::::::::::::: :.:::: :::: :: :::::.:: CCDS81 GDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVFLEYGQD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 LSVRGKNKKEKLEDFFKNMVKSADGVIV---SGVKDVDDFFEHERTFLLEYHNRVKDASA :::::::.:: : :..:.::::: ... ::.:.::::::::::::::::.:..:: CCDS81 LSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 KSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADED ..::. :.:: :::: :...: .::::. ... :::..:::.. ::.:.::..::: CCDS81 RADRVMRAHKCLADDYIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDED 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB6 LKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQ :::::.:.::.:.::::::::::: :.:.:::::::::::::..:..: ::. :::::: CCDS81 LKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESHQQLCCQ 290 300 310 320 330 340 370 380 390 400 410 pF1KB6 KFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT .::..:.::::::.:::.:::..:::::.:::::::::::.. .:.: :..:.:. CCDS81 RFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKHAKASTLILRNTLVALKGEP 350 360 370 380 390 400 >>CCDS13130.1 SNX5 gene_id:27131|Hs108|chr20 (404 aa) initn: 1767 init1: 1739 opt: 1772 Z-score: 1902.6 bits: 361.0 E(32554): 1.2e-99 Smith-Waterman score: 1772; 64.5% identity (90.0% similar) in 400 aa overlap (21-417:5-404) 10 20 30 40 50 pF1KB6 MRACAGPRLGAAMMEGLDDGPDFLS--EEDRG-LKAINVDLQSDAALQVDISDALSERDK :..:. ::::. :....:::. : .::.:: :::::::: CCDS13 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDK 10 20 30 40 60 70 80 90 100 110 pF1KB6 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE ::::::::..::.:.. ::::.::::.:.::::...:. :::: :::::: .::::. :: CCDS13 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV :.:::::::::::::::.::::::::::::.:::::. ::::: :...::.: .: :::: CCDS13 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 FLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVK ::::.:::::: :: :: . :::..::::: :. .:::.::::::.:..::..:.::.: CCDS13 FLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIK 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 DASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVS :. .:.:.::::::..:::: . .. :..:. .. : : :..:::.:::.: ::.:.::: CCDS13 DSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVS 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB6 ADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQ .::::::..::.::. . .:::::::::...:.::::.:::::::: :.::: ::. :: CCDS13 SDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQ 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB6 LCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGD ::::::..:::::.:::.:: .:::::::::.:..:::.:::..:..:::.:. ..... CCDS13 ECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN 350 360 370 380 390 400 pF1KB6 T 418 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:11:36 2016 done: Sat Nov 5 11:11:37 2016 Total Scan time: 3.040 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]