FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6639, 418 aa 1>>>pF1KB6639 418 - 418 aa - 418 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9339+/-0.00041; mu= 18.9951+/- 0.025 mean_var=61.7451+/-12.695, 0's: 0 Z-trim(111.2): 47 B-trim: 468 in 1/49 Lambda= 0.163220 statistics sampled from 19701 (19744) to 19701 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.596), E-opt: 0.2 (0.231), width: 16 Scan time: 6.480 The best scores are: opt bits E(85289) NP_005712 (OMIM: 604222) actin-related protein 3 i ( 418) 2839 677.4 1.8e-194 NP_001264069 (OMIM: 604222) actin-related protein ( 367) 2491 595.4 7.6e-170 NP_001005386 (OMIM: 604221) actin-related protein ( 399) 666 165.7 1.9e-40 NP_005713 (OMIM: 604221) actin-related protein 2 i ( 394) 592 148.3 3.3e-35 NP_001092 (OMIM: 102630,243310,607371,608578) acti ( 375) 590 147.8 4.4e-35 NP_001186883 (OMIM: 102560,604717,614583) actin, c ( 375) 590 147.8 4.4e-35 NP_001605 (OMIM: 102560,604717,614583) actin, cyto ( 375) 590 147.8 4.4e-35 NP_001017992 (OMIM: 614835) beta-actin-like protei ( 376) 582 145.9 1.6e-34 NP_001091 (OMIM: 102610,161800,255310,616852) acti ( 377) 578 144.9 3.1e-34 NP_005150 (OMIM: 102540,612098,612794,613424) acti ( 377) 578 144.9 3.1e-34 NP_001606 (OMIM: 102545) actin, gamma-enteric smoo ( 376) 575 144.2 5.1e-34 NP_001307784 (OMIM: 102620,611788,613834,614042) a ( 377) 575 144.2 5.1e-34 NP_001604 (OMIM: 102620,611788,613834,614042) acti ( 377) 575 144.2 5.1e-34 NP_001135417 (OMIM: 102620,611788,613834,614042) a ( 377) 575 144.2 5.1e-34 XP_016859649 (OMIM: 608914) PREDICTED: POTE ankyri ( 657) 522 131.9 4.5e-30 XP_011509518 (OMIM: 608914) PREDICTED: POTE ankyri ( 957) 522 132.0 6.2e-30 XP_016859648 (OMIM: 608914) PREDICTED: POTE ankyri ( 967) 522 132.0 6.2e-30 XP_016859650 (OMIM: 608914) PREDICTED: POTE ankyri (1075) 522 132.1 6.8e-30 NP_001077007 (OMIM: 608914) POTE ankyrin domain fa (1075) 522 132.1 6.8e-30 NP_005727 (OMIM: 605143) alpha-centractin [Homo sa ( 376) 501 126.8 8.9e-29 NP_005726 (OMIM: 605144) beta-centractin [Homo sap ( 376) 497 125.9 1.7e-28 XP_016858605 (OMIM: 605144) PREDICTED: beta-centra ( 332) 489 124.0 5.7e-28 NP_536356 (OMIM: 608535) actin-related protein T2 ( 377) 453 115.5 2.3e-25 NP_612146 (OMIM: 300487) actin-related protein T1 ( 376) 439 112.2 2.2e-24 NP_115876 (OMIM: 608534) actin-related protein T3 ( 372) 434 111.0 5e-24 XP_005263911 (OMIM: 605144) PREDICTED: beta-centra ( 302) 431 110.3 6.9e-24 NP_006677 (OMIM: 604304) actin-like protein 7B [Ho ( 415) 411 105.7 2.3e-22 NP_057272 (OMIM: 612458) actin-like protein 6B [Ho ( 426) 403 103.8 8.7e-22 NP_006678 (OMIM: 604303) actin-like protein 7A [Ho ( 435) 395 101.9 3.3e-21 NP_001186822 (OMIM: 102545) actin, gamma-enteric s ( 333) 386 99.7 1.2e-20 NP_004292 (OMIM: 604958) actin-like protein 6A iso ( 429) 379 98.1 4.4e-20 NP_817126 (OMIM: 604958) actin-like protein 6A iso ( 387) 348 90.8 6.4e-18 NP_829888 (OMIM: 604958) actin-like protein 6A iso ( 387) 348 90.8 6.4e-18 >>NP_005712 (OMIM: 604222) actin-related protein 3 isofo (418 aa) initn: 2839 init1: 2839 opt: 2839 Z-score: 3612.3 bits: 677.4 E(85289): 1.8e-194 Smith-Waterman score: 2839; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB6 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FIGDEAIEKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FIGDEAIEKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 AEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 AEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 EFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKP 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 KPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS 370 380 390 400 410 >>NP_001264069 (OMIM: 604222) actin-related protein 3 is (367 aa) initn: 2491 init1: 2491 opt: 2491 Z-score: 3170.3 bits: 595.4 E(85289): 7.6e-170 Smith-Waterman score: 2491; 100.0% identity (100.0% similar) in 367 aa overlap (52-418:1-367) 30 40 50 60 70 80 pF1KB6 AGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGDEAIEKPTYATKWPIRHG :::::::::::::::::::::::::::::: NP_001 MKGVDDLDFFIGDEAIEKPTYATKWPIRHG 10 20 30 90 100 110 120 130 140 pF1KB6 IVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYI 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 AVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 YFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINA 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 ISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVL 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB6 SGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGG 280 290 300 310 320 330 390 400 410 pF1KB6 SMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS ::::::::::::::::::::::::::::::::::::: NP_001 SMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS 340 350 360 >>NP_001005386 (OMIM: 604221) actin-related protein 2 is (399 aa) initn: 614 init1: 206 opt: 666 Z-score: 847.2 bits: 165.7 E(85289): 1.9e-40 Smith-Waterman score: 715; 34.3% identity (64.7% similar) in 408 aa overlap (3-404:5-387) 10 20 30 40 50 pF1KB6 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIA---IKESAKVGDQAQRRVMKGV :: . : : :::..: ::::.. :. :.:. .. :. ..:::. .:. NP_001 MDSQGR-KVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIE----IKNN 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 DDLDFFIGDEAIE-KPTYATKWPIRHGIVEDWDLMERFMEQVIF-KYLRAEPEDHYFLLT .:...:::: : . ...:...:::..:: :... . .. . : . .. .::: NP_001 KKMDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 EPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDG :::.: .::: .:.:::... :.:.:.::::.: : . :::.:.::::: NP_001 EPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYA--------QGLLTGVVVDSGDG 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 VTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSY :::. :: ::. . ... ::::::: .. .:: : .. ..::.. .::. : NP_001 VTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCY 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 VCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFT : .. .: .: . . ...:: .. : :: ::: .:: .:.:.. : . . NP_001 VGYNIEQE-QKLALETTVLVESYTLPDG-----RIIKVGGERFEAPEALFQPHLINVEGV 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB6 QPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEEL ..:.. ..:: ::.: .::.:::::::::. . ::.:.::. : : . : NP_001 G-VAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQ-----LYLERVL 290 300 310 320 330 360 370 380 390 400 410 pF1KB6 SGGRLKPKPIDVQVITHHMQRYAVWFGGSMLAST-PEFYQVCHTKKDYEEIGPSICRHNP .: : . . ... ... :..::..::. . . :...:.: : NP_001 KGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLG 340 350 360 370 380 390 pF1KB6 VFGVMS NP_001 VTVR >>NP_005713 (OMIM: 604221) actin-related protein 2 isofo (394 aa) initn: 635 init1: 206 opt: 592 Z-score: 753.1 bits: 148.3 E(85289): 3.3e-35 Smith-Waterman score: 702; 34.1% identity (64.2% similar) in 408 aa overlap (3-404:5-382) 10 20 30 40 50 pF1KB6 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIA---IKESAKVGDQAQRRVMKGV :: . : : :::..: ::::.. :. :.:. .. :. ..:::. . NP_005 MDSQGR-KVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGN---------I 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 DDLDFFIGDEAIE-KPTYATKWPIRHGIVEDWDLMERFMEQVIF-KYLRAEPEDHYFLLT . :...:::: : . ...:...:::..:: :... . .. . : . .. .::: NP_005 EIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 EPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDG :::.: .::: .:.:::... :.:.:.::::.: : . :::.:.::::: NP_005 EPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYA--------QGLLTGVVVDSGDG 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 VTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSY :::. :: ::. . ... ::::::: .. .:: : .. ..::.. .::. : NP_005 VTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCY 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 VCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFT : .. .: .: . . ...:: .. : :: ::: .:: .:.:.. : . . NP_005 VGYNIEQE-QKLALETTVLVESYTLPDG-----RIIKVGGERFEAPEALFQPHLINVEGV 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 QPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEEL ..:.. ..:: ::.: .::.:::::::::. . ::.:.::. : : . : NP_005 G-VAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQ-----LYLERVL 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB6 SGGRLKPKPIDVQVITHHMQRYAVWFGGSMLAST-PEFYQVCHTKKDYEEIGPSICRHNP .: : . . ... ... :..::..::. . . :...:.: : NP_005 KGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLG 340 350 360 370 380 390 pF1KB6 VFGVMS NP_005 VTVR >>NP_001092 (OMIM: 102630,243310,607371,608578) actin, c (375 aa) initn: 812 init1: 295 opt: 590 Z-score: 750.9 bits: 147.8 E(85289): 4.4e-35 Smith-Waterman score: 845; 37.3% identity (62.7% similar) in 415 aa overlap (1-414:1-375) 10 20 30 40 50 60 pF1KB6 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDF : . : ::: :.:. : :.::. :. ..:: :: .. :: :. . : NP_001 MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQKDS 10 20 30 40 50 70 80 90 100 110 pF1KB6 FIGDEAIEKPTYAT-KWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNT ..:::: : : :.::.:::: .:: ::.. ...... ::. ::.: :::: ::: NP_001 YVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 PENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIP ::: ..::::.::.:..:.:.::::.: :: : :: :: :.::::::::..: NP_001 KANREKMTQIMFETFNTPAMYVAIQAVLSLYAS------G-RT-TGIVMDSGDGVTHTVP 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 VAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLV . :::.. : .. .::::.: .....: .: .. : .. .::. :: :. NP_001 IYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFE 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 KEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEV .:. .. :. :.: .. : .: ::: :: .:.: : . . . : :. NP_001 QEMATAASS-SSLEKSYELPDGQV-----ITIGNERFRCPEALFQPSFLGME-SCGIHET 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 VDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLK . . :..: .:.:. :: : :::::.::. .. :.:... : NP_001 TFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITA----------------LA 280 290 300 310 320 360 370 380 390 400 410 pF1KB6 PKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS :. . ...:. ..:.::.:::.::: : :. .:..:.: :::: : : NP_001 PSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIV-HRKCF 330 340 350 360 370 >>NP_001186883 (OMIM: 102560,604717,614583) actin, cytop (375 aa) initn: 735 init1: 295 opt: 590 Z-score: 750.9 bits: 147.8 E(85289): 4.4e-35 Smith-Waterman score: 845; 37.1% identity (62.9% similar) in 415 aa overlap (1-414:1-375) 10 20 30 40 50 60 pF1KB6 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDF : .. : :.: :.:. : :.::. :. ..:: :: .. :: :. . : NP_001 MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQKDS 10 20 30 40 50 70 80 90 100 110 pF1KB6 FIGDEAIEKPTYAT-KWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNT ..:::: : : :.::.:::: .:: ::.. ...... ::. ::.: :::: ::: NP_001 YVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 PENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIP ::: ..::::.::.:..:.:.::::.: :: : :: :: :.::::::::..: NP_001 KANREKMTQIMFETFNTPAMYVAIQAVLSLYAS------G-RT-TGIVMDSGDGVTHTVP 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 VAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLV . :::.. : .. .::::.: .....: .: .. : .. .::. :: :. NP_001 IYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFE 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 KEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEV .:. .. :. :.: .. : .: ::: :: .:.: : . . . : :. NP_001 QEMATAASS-SSLEKSYELPDGQV-----ITIGNERFRCPEALFQPSFLGME-SCGIHET 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 VDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLK . . :..: .:.:. :: : :::::.::. .. :.:... : NP_001 TFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITA----------------LA 280 290 300 310 320 360 370 380 390 400 410 pF1KB6 PKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS :. . ...:. ..:.::.:::.::: : :. .:..:.: :::: : : NP_001 PSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIV-HRKCF 330 340 350 360 370 >>NP_001605 (OMIM: 102560,604717,614583) actin, cytoplas (375 aa) initn: 735 init1: 295 opt: 590 Z-score: 750.9 bits: 147.8 E(85289): 4.4e-35 Smith-Waterman score: 845; 37.1% identity (62.9% similar) in 415 aa overlap (1-414:1-375) 10 20 30 40 50 60 pF1KB6 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDF : .. : :.: :.:. : :.::. :. ..:: :: .. :: :. . : NP_001 MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQKDS 10 20 30 40 50 70 80 90 100 110 pF1KB6 FIGDEAIEKPTYAT-KWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNT ..:::: : : :.::.:::: .:: ::.. ...... ::. ::.: :::: ::: NP_001 YVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 PENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIP ::: ..::::.::.:..:.:.::::.: :: : :: :: :.::::::::..: NP_001 KANREKMTQIMFETFNTPAMYVAIQAVLSLYAS------G-RT-TGIVMDSGDGVTHTVP 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 VAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLV . :::.. : .. .::::.: .....: .: .. : .. .::. :: :. NP_001 IYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFE 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 KEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEV .:. .. :. :.: .. : .: ::: :: .:.: : . . . : :. NP_001 QEMATAASS-SSLEKSYELPDGQV-----ITIGNERFRCPEALFQPSFLGME-SCGIHET 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 VDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLK . . :..: .:.:. :: : :::::.::. .. :.:... : NP_001 TFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITA----------------LA 280 290 300 310 320 360 370 380 390 400 410 pF1KB6 PKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS :. . ...:. ..:.::.:::.::: : :. .:..:.: :::: : : NP_001 PSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIV-HRKCF 330 340 350 360 370 >>NP_001017992 (OMIM: 614835) beta-actin-like protein 2 (376 aa) initn: 732 init1: 285 opt: 582 Z-score: 740.7 bits: 145.9 E(85289): 1.6e-34 Smith-Waterman score: 836; 37.0% identity (63.3% similar) in 411 aa overlap (5-414:6-376) 10 20 30 40 50 pF1KB6 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLD : : ::: :.:. : :..:. :. ..:: : : .. :: :. . : NP_001 MTDNELSALVVDNGSGMCKAGFGGDDAPRAVFPSMI--------GRPRHQGVMVGMGQKD 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 FFIGDEAIEKPTYAT-KWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLN ..:::: : : :.::.::.: .:: ::.. ..... ::. :..: .:::: ::: NP_001 CYVGDEAQSKRGVLTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 TPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVI ::: ..::::.::.:..:.:.::::.: :: : :: :: :.::::::::.. NP_001 PKINREKMTQIMFEAFNTPAMYVAIQAVLSLYAS------G-RT-TGIVMDSGDGVTHIV 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 PVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDL :. :::.. : .. .::::.: .....: .: .. : .. :::. :: :. NP_001 PIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDF 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 VKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISE .:. . ...: ..: .. : .: ::: :: .:.: : . . .. : : NP_001 EQEMVRAAASSSPE-RSYELPDGQV-----ITIGNERFRCPEAIFQPSFLGIE-SSGIHE 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 VVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRL .. . :..: .:.:. :: : ::::::::. .. :.:... : NP_001 TTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIIT----------------L 280 290 300 310 320 360 370 380 390 400 410 pF1KB6 KPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS :. . ...:. ..:.::.:::.::: : :. .:..:.: :: : : : NP_001 APSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIV-HRKCF 330 340 350 360 370 >>NP_001091 (OMIM: 102610,161800,255310,616852) actin, a (377 aa) initn: 784 init1: 298 opt: 578 Z-score: 735.6 bits: 144.9 E(85289): 3.1e-34 Smith-Waterman score: 840; 37.7% identity (62.6% similar) in 409 aa overlap (7-414:9-377) 10 20 30 40 50 pF1KB6 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDL : : : :.: .: :.::. :. ..:: :: .. :: :. . NP_001 MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 DFFIGDEAIEKPTYAT-KWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPL : ..:::: : : :.::.:::. .:: ::.. ...... ::. ::.: :::: :: NP_001 DSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 NTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHV : ::: ..::::.::::..:.:.::::.: :: : :: :: :.:::::::: NP_001 NPKANREKMTQIMFETFNVPAMYVAIQAVLSLYAS------G-RT-TGIVLDSGDGVTHN 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 IPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPD .:. :::.. : .. .::::.: .....: .: .. : .. .::. :: : NP_001 VPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALD 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 LVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPIS . .:. .. :. :.: .. : .: ::: :: .:.: : . . . : NP_001 FENEMATAASS-SSLEKSYELPDGQ-----VITIGNERFRCPETLFQPSFIGME-SAGIH 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 EVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGR :.. . :..: ::.:. :: : :.:::.::. .. :.:... NP_001 ETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITA---------------- 280 290 300 310 320 360 370 380 390 400 410 pF1KB6 LKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVM : :. . ...:. ..:.::.:::.::: : :. ::..:.: :::: : : NP_001 LAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIV-HRKCF 330 340 350 360 370 pF1KB6 S >>NP_005150 (OMIM: 102540,612098,612794,613424) actin, a (377 aa) initn: 760 init1: 298 opt: 578 Z-score: 735.6 bits: 144.9 E(85289): 3.1e-34 Smith-Waterman score: 839; 37.7% identity (62.6% similar) in 409 aa overlap (7-414:9-377) 10 20 30 40 50 pF1KB6 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDL : : : :.: .: :.::. :. ..:: :: .. :: :. . NP_005 MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 DFFIGDEAIEKPTYAT-KWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPL : ..:::: : : :.::.:::. .:: ::.. ...... ::. ::.: :::: :: NP_005 DSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 NTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHV : ::: ..::::.::::..:.:.::::.: :: : :: :: :.:::::::: NP_005 NPKANREKMTQIMFETFNVPAMYVAIQAVLSLYAS------G-RT-TGIVLDSGDGVTHN 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 IPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPD .:. :::.. : .. .::::.: .....: .: .. : .. .::. :: : NP_005 VPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALD 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 LVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPIS . .:. .. :. :.: .. : .: ::: :: .:.: : . . . : NP_005 FENEMATAASS-SSLEKSYELPDGQ-----VITIGNERFRCPETLFQPSFIGME-SAGIH 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 EVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGR :.. . :..: ::.:. :: : :::::.::. .. :.:... NP_005 ETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITA---------------- 280 290 300 310 320 360 370 380 390 400 410 pF1KB6 LKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVM : :. . ...:. ..:.::.:::.::: : :. .:..:.: :::: : : NP_005 LAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIV-HRKCF 330 340 350 360 370 pF1KB6 S 418 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:12:55 2016 done: Sat Nov 5 11:12:56 2016 Total Scan time: 6.480 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]