FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6647, 404 aa 1>>>pF1KB6647 404 - 404 aa - 404 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3666+/-0.000345; mu= 4.3099+/- 0.021 mean_var=237.3936+/-48.965, 0's: 0 Z-trim(122.6): 88 B-trim: 847 in 2/59 Lambda= 0.083241 statistics sampled from 40890 (40996) to 40890 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.481), width: 16 Scan time: 8.460 The best scores are: opt bits E(85289) NP_001127 (OMIM: 600214) advanced glycosylation en ( 404) 2756 343.6 5e-94 NP_001193861 (OMIM: 600214) advanced glycosylation ( 390) 2306 289.6 9.1e-78 NP_001193895 (OMIM: 600214) advanced glycosylation ( 347) 2289 287.5 3.4e-77 NP_001193869 (OMIM: 600214) advanced glycosylation ( 347) 2289 287.5 3.4e-77 NP_001193865 (OMIM: 600214) advanced glycosylation ( 355) 1923 243.5 6e-64 NP_001193883 (OMIM: 600214) advanced glycosylation ( 325) 1896 240.3 5.3e-63 NP_001193858 (OMIM: 600214) advanced glycosylation ( 420) 1808 229.8 9.6e-60 NP_751947 (OMIM: 600214) advanced glycosylation en ( 342) 1446 186.2 1e-46 NP_001193863 (OMIM: 600214) advanced glycosylation ( 363) 1341 173.7 6.6e-43 XP_016865817 (OMIM: 600214) PREDICTED: advanced gl ( 372) 958 127.7 4.7e-29 NP_001230210 (OMIM: 601662) CD166 antigen isoform ( 555) 307 49.7 2.1e-05 NP_001230209 (OMIM: 601662) CD166 antigen isoform ( 570) 307 49.7 2.2e-05 NP_001618 (OMIM: 601662) CD166 antigen isoform 1 p ( 583) 307 49.7 2.2e-05 XP_016873251 (OMIM: 155735) PREDICTED: cell surfac ( 583) 285 47.0 0.00014 XP_016873250 (OMIM: 155735) PREDICTED: cell surfac ( 604) 285 47.1 0.00014 XP_016873249 (OMIM: 155735) PREDICTED: cell surfac ( 614) 285 47.1 0.00014 XP_016873248 (OMIM: 155735) PREDICTED: cell surfac ( 625) 285 47.1 0.00015 NP_006491 (OMIM: 155735) cell surface glycoprotein ( 646) 285 47.1 0.00015 >>NP_001127 (OMIM: 600214) advanced glycosylation end pr (404 aa) initn: 2756 init1: 2756 opt: 2756 Z-score: 1809.1 bits: 343.6 E(85289): 5e-94 Smith-Waterman score: 2756; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404) 10 20 30 40 50 60 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV 310 320 330 340 350 360 370 380 390 400 pF1KB6 ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP :::::::::::::::::::::::::::::::::::::::::::: NP_001 ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP 370 380 390 400 >>NP_001193861 (OMIM: 600214) advanced glycosylation end (390 aa) initn: 2300 init1: 2300 opt: 2306 Z-score: 1517.2 bits: 289.6 E(85289): 9.1e-78 Smith-Waterman score: 2622; 96.5% identity (96.5% similar) in 404 aa overlap (1-404:1-390) 10 20 30 40 50 60 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKL------- 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------GGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB6 CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV 290 300 310 320 330 340 370 380 390 400 pF1KB6 ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP :::::::::::::::::::::::::::::::::::::::::::: NP_001 ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP 350 360 370 380 390 >>NP_001193895 (OMIM: 600214) advanced glycosylation end (347 aa) initn: 2289 init1: 2289 opt: 2289 Z-score: 1506.8 bits: 287.5 E(85289): 3.4e-77 Smith-Waterman score: 2289; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331) 10 20 30 40 50 60 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV ::::::::::::::::::::::::::::::: NP_001 CVATHSSHGPQESRAVSISIIEPGEEGPTAGEGFDKVREAEDSPQHM 310 320 330 340 370 380 390 400 pF1KB6 ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP >>NP_001193869 (OMIM: 600214) advanced glycosylation end (347 aa) initn: 2289 init1: 2289 opt: 2289 Z-score: 1506.8 bits: 287.5 E(85289): 3.4e-77 Smith-Waterman score: 2289; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331) 10 20 30 40 50 60 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV ::::::::::::::::::::::::::::::: NP_001 CVATHSSHGPQESRAVSISIIEPGEEGPTAGEGFDKVREAEDSPQHM 310 320 330 340 370 380 390 400 pF1KB6 ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP >>NP_001193865 (OMIM: 600214) advanced glycosylation end (355 aa) initn: 1958 init1: 1921 opt: 1923 Z-score: 1269.1 bits: 243.5 E(85289): 6e-64 Smith-Waterman score: 1923; 87.4% identity (92.9% similar) in 326 aa overlap (1-326:1-323) 10 20 30 40 50 60 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS :::::::::::::::::::::::::::::::::::. : . .: ::. ... : NP_001 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGLRTREPTAVWPPIPATGPR-KAVLS 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV :. ::. .... ..:. :.. NP_001 --ASASSNQARRGQLQVRGLIKSGKQKIAPNTCDWGDGQQERNGRPQKTRRKRRSVQN 300 310 320 330 340 350 >>NP_001193883 (OMIM: 600214) advanced glycosylation end (325 aa) initn: 1896 init1: 1896 opt: 1896 Z-score: 1252.1 bits: 240.3 E(85289): 5.3e-63 Smith-Waterman score: 1896; 100.0% identity (100.0% similar) in 274 aa overlap (1-274:1-274) 10 20 30 40 50 60 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS :::::::::::::::::::::::::::::::::: NP_001 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDNQARRGQLQVRGLIKSGKQKIAPNTC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV NP_001 DWGDGQQERNGRPQKTRRKRRSVQN 310 320 >>NP_001193858 (OMIM: 600214) advanced glycosylation end (420 aa) initn: 1804 init1: 1804 opt: 1808 Z-score: 1193.6 bits: 229.8 E(85289): 9.6e-60 Smith-Waterman score: 2714; 96.2% identity (96.2% similar) in 420 aa overlap (1-404:1-420) 10 20 30 40 50 60 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI 70 80 90 100 110 120 130 140 150 160 pF1KB6 PGKPEIVDSASELTAGVPNKV----------------GTCVSEGSYPAGTLSWHLDGKPL ::::::::::::::::::::: ::::::::::::::::::::::: NP_001 PGKPEIVDSASELTAGVPNKVVEESRRSRKRPCEQEVGTCVSEGSYPAGTLSWHLDGKPL 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 VPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAP 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 IQPRVWEPVPLEEVQLVVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQPRVWEPVPLEEVQLVVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB6 VLILPEIGPQDQGTYSCVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLILPEIGPQDQGTYSCVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALA 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB6 LGILGGLGTAALLIGVILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGILGGLGTAALLIGVILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP 370 380 390 400 410 420 >>NP_751947 (OMIM: 600214) advanced glycosylation end pr (342 aa) initn: 1464 init1: 1440 opt: 1446 Z-score: 959.7 bits: 186.2 E(85289): 1e-46 Smith-Waterman score: 1762; 94.9% identity (94.9% similar) in 274 aa overlap (1-274:1-260) 10 20 30 40 50 60 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKL------- 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 -------GGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS :::::::::::::::::::::::::::::::::: NP_751 VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDVSDLERGAGRTRRGGANCRLCGRIRA 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB6 CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV NP_751 GNSSPGPGDPGRPGDSRPAHWGHLVAKAATPRRGEEGPRKPGGRGGACRTESVGGT 290 300 310 320 330 340 >>NP_001193863 (OMIM: 600214) advanced glycosylation end (363 aa) initn: 1337 init1: 1337 opt: 1341 Z-score: 891.3 bits: 173.7 E(85289): 6.6e-43 Smith-Waterman score: 2247; 95.4% identity (95.4% similar) in 347 aa overlap (1-331:1-347) 10 20 30 40 50 60 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI 70 80 90 100 110 120 130 140 150 160 pF1KB6 PGKPEIVDSASELTAGVPNKV----------------GTCVSEGSYPAGTLSWHLDGKPL ::::::::::::::::::::: ::::::::::::::::::::::: NP_001 PGKPEIVDSASELTAGVPNKVVEESRRSRKRPCEQEVGTCVSEGSYPAGTLSWHLDGKPL 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 VPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAP 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 IQPRVWEPVPLEEVQLVVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQPRVWEPVPLEEVQLVVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB6 VLILPEIGPQDQGTYSCVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALA ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLILPEIGPQDQGTYSCVATHSSHGPQESRAVSISIIEPGEEGPTAGEGFDKVREAEDSP 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB6 LGILGGLGTAALLIGVILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP NP_001 QHM >>XP_016865817 (OMIM: 600214) PREDICTED: advanced glycos (372 aa) initn: 987 init1: 958 opt: 958 Z-score: 642.5 bits: 127.7 E(85289): 4.7e-29 Smith-Waterman score: 1854; 94.5% identity (94.5% similar) in 290 aa overlap (1-274:32-321) 10 20 30 pF1KB6 MAAGTAVGAWVLVLSLWGAVVGAQNITARI :::::::::::::::::::::::::::::: XP_016 GAGERVQAPPRAEATAGRGADRARTLEGSRMAAGTAVGAWVLVLSLWGAVVGAQNITARI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 GEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGGGPWDSVARVLPNGSLFLPAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGGGPWDSVARVLPNGSLFLPAVG 70 80 90 100 110 120 100 110 120 130 140 pF1KB6 IQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNKV--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNKVVEESRRSRK 130 140 150 160 170 180 150 160 170 180 190 pF1KB6 -------GTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPCEQEVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMV 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB6 TPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQLVVEPEGGAVAPGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQLVVEPEGGAVAPGGT 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB6 VTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYSCVATHSSHGPQESR :::::::::::::::::::: XP_016 VTLTCEVPAQPSPQIHWMKDNQARRGQLQVRGLIKSGKQKIAPNTCDWGDGQQERNGRPQ 310 320 330 340 350 360 404 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:14:45 2016 done: Sat Nov 5 11:14:46 2016 Total Scan time: 8.460 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]