Result of FASTA (omim) for
pF1KB6648
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6648, 445 aa
1>>>pF1KB6648 445 - 445 aa - 445 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.5281+/-0.000649; mu= -37.7280+/- 0.039
mean_var=881.6099+/-191.990, 0's: 0 Z-trim(115.9): 1184 B-trim: 0 in 0/57
Lambda= 0.043195
statistics sampled from 25238 (26702) to 25238 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.313), width: 16
Scan time: 9.440
The best scores are: opt bits E(85289)
NP_002488 (OMIM: 604043,615565) serine/threonine-p ( 445) 2883 195.8 1.9e-49
XP_005273204 (OMIM: 604043,615565) PREDICTED: seri ( 437) 2809 191.2 4.5e-48
NP_001191111 (OMIM: 604043,615565) serine/threonin ( 388) 2424 167.2 7e-41
NP_001191112 (OMIM: 604043,615565) serine/threonin ( 384) 2420 166.9 8.2e-41
XP_011533370 (OMIM: 616731) PREDICTED: serine/thre ( 483) 686 59.0 3.3e-08
XP_006719871 (OMIM: 616731) PREDICTED: serine/thre ( 598) 686 59.0 3.8e-08
XP_011533368 (OMIM: 616731) PREDICTED: serine/thre ( 697) 686 59.1 4.3e-08
NP_954983 (OMIM: 616731) serine/threonine-protein ( 708) 686 59.1 4.3e-08
XP_016876045 (OMIM: 616731) PREDICTED: serine/thre ( 737) 686 59.1 4.4e-08
XP_016876044 (OMIM: 616731) PREDICTED: serine/thre ( 755) 686 59.1 4.5e-08
XP_016876046 (OMIM: 616731) PREDICTED: serine/thre ( 780) 686 59.2 4.6e-08
XP_011532342 (OMIM: 601959) PREDICTED: serine/thre ( 671) 648 56.7 2.1e-07
XP_006713373 (OMIM: 601959) PREDICTED: serine/thre ( 795) 648 56.8 2.4e-07
XP_016862575 (OMIM: 601959) PREDICTED: serine/thre ( 824) 648 56.8 2.5e-07
NP_003148 (OMIM: 601959) serine/threonine-protein ( 841) 648 56.8 2.5e-07
XP_011532341 (OMIM: 601959) PREDICTED: serine/thre ( 842) 648 56.8 2.5e-07
XP_016862574 (OMIM: 601959) PREDICTED: serine/thre ( 870) 648 56.8 2.6e-07
NP_665917 (OMIM: 609779) serine/threonine-protein ( 470) 624 55.1 4.7e-07
NP_001308152 (OMIM: 609779) serine/threonine-prote ( 482) 624 55.1 4.8e-07
NP_001139475 (OMIM: 609779) serine/threonine-prote ( 599) 624 55.2 5.6e-07
XP_016862702 (OMIM: 609779) PREDICTED: serine/thre ( 599) 624 55.2 5.6e-07
XP_016862703 (OMIM: 609779) PREDICTED: serine/thre ( 599) 624 55.2 5.6e-07
NP_001308149 (OMIM: 609779) serine/threonine-prote ( 645) 624 55.2 5.9e-07
XP_011511469 (OMIM: 609779) PREDICTED: serine/thre ( 645) 624 55.2 5.9e-07
NP_079076 (OMIM: 609779) serine/threonine-protein ( 645) 624 55.2 5.9e-07
XP_016862705 (OMIM: 609779) PREDICTED: serine/thre ( 563) 601 53.7 1.4e-06
XP_016862704 (OMIM: 609779) PREDICTED: serine/thre ( 563) 601 53.7 1.4e-06
XP_016862701 (OMIM: 609779) PREDICTED: serine/thre ( 609) 601 53.8 1.5e-06
NP_055212 (OMIM: 604884) serine/threonine-protein ( 313) 579 52.1 2.4e-06
NP_001159642 (OMIM: 604884) serine/threonine-prote ( 313) 579 52.1 2.4e-06
XP_006716999 (OMIM: 604884) PREDICTED: serine/thre ( 313) 579 52.1 2.4e-06
XP_005251721 (OMIM: 604884) PREDICTED: serine/thre ( 313) 579 52.1 2.4e-06
NP_001159640 (OMIM: 604884) serine/threonine-prote ( 313) 579 52.1 2.4e-06
NP_001159639 (OMIM: 604884) serine/threonine-prote ( 331) 579 52.1 2.5e-06
NP_001159641 (OMIM: 604884) serine/threonine-prote ( 338) 579 52.1 2.6e-06
XP_016869706 (OMIM: 604884) PREDICTED: serine/thre ( 347) 579 52.2 2.6e-06
NP_001138473 (OMIM: 604884) serine/threonine-prote ( 347) 579 52.2 2.6e-06
NP_001159643 (OMIM: 604884) serine/threonine-prote ( 347) 579 52.2 2.6e-06
NP_689933 (OMIM: 604044) serine/threonine-protein ( 506) 576 52.1 3.9e-06
NP_002489 (OMIM: 604044) serine/threonine-protein ( 506) 576 52.1 3.9e-06
NP_598001 (OMIM: 606848) serine/threonine-protein ( 302) 566 51.3 4.2e-06
NP_001139571 (OMIM: 604044) serine/threonine-prote ( 489) 568 51.6 5.4e-06
XP_016855833 (OMIM: 606848) PREDICTED: serine/thre ( 310) 540 49.7 1.3e-05
XP_016855834 (OMIM: 606848) PREDICTED: serine/thre ( 310) 540 49.7 1.3e-05
XP_011530307 (OMIM: 263520,604588) PREDICTED: seri ( 715) 549 50.6 1.6e-05
NP_001186328 (OMIM: 263520,604588) serine/threonin (1189) 549 50.8 2.3e-05
XP_011530306 (OMIM: 263520,604588) PREDICTED: seri (1214) 549 50.8 2.4e-05
NP_001186329 (OMIM: 263520,604588) serine/threonin (1214) 549 50.8 2.4e-05
XP_006714291 (OMIM: 263520,604588) PREDICTED: seri (1227) 549 50.8 2.4e-05
NP_001186327 (OMIM: 263520,604588) serine/threonin (1242) 549 50.8 2.4e-05
>>NP_002488 (OMIM: 604043,615565) serine/threonine-prote (445 aa)
initn: 2883 init1: 2883 opt: 2883 Z-score: 1008.8 bits: 195.8 E(85289): 1.9e-49
Smith-Waterman score: 2883; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)
10 20 30 40 50 60
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 YYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 RKFLSLASNPELLNLPSSVIKKKVHFSGESKENIMRSENSESQLTSKSKCKDLKKRLHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RKFLSLASNPELLNLPSSVIKKKVHFSGESKENIMRSENSESQLTSKSKCKDLKKRLHAA
370 380 390 400 410 420
430 440
pF1KB6 QLRAQALSDIEKNYQLKSRQILGMR
:::::::::::::::::::::::::
NP_002 QLRAQALSDIEKNYQLKSRQILGMR
430 440
>>XP_005273204 (OMIM: 604043,615565) PREDICTED: serine/t (437 aa)
initn: 2821 init1: 2418 opt: 2809 Z-score: 984.0 bits: 191.2 E(85289): 4.5e-48
Smith-Waterman score: 2809; 98.2% identity (98.2% similar) in 445 aa overlap (1-445:1-437)
10 20 30 40 50 60
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 YYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 RKFLSLASNPELLNLPSSVIKKKVHFSGESKENIMRSENSESQLTSKSKCKDLKKRLHAA
:::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_005 RKFLSLASNP--------VIKKKVHFSGESKENIMRSENSESQLTSKSKCKDLKKRLHAA
370 380 390 400 410
430 440
pF1KB6 QLRAQALSDIEKNYQLKSRQILGMR
:::::::::::::::::::::::::
XP_005 QLRAQALSDIEKNYQLKSRQILGMR
420 430
>>NP_001191111 (OMIM: 604043,615565) serine/threonine-pr (388 aa)
initn: 2424 init1: 2424 opt: 2424 Z-score: 855.0 bits: 167.2 E(85289): 7e-41
Smith-Waterman score: 2424; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371)
10 20 30 40 50 60
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 YYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 RKFLSLASNPELLNLPSSVIKKKVHFSGESKENIMRSENSESQLTSKSKCKDLKKRLHAA
:::::::::::
NP_001 RKFLSLASNPESHFVAQAGMQWCDHSSM
370 380
>>NP_001191112 (OMIM: 604043,615565) serine/threonine-pr (384 aa)
initn: 2418 init1: 2418 opt: 2420 Z-score: 853.7 bits: 166.9 E(85289): 8.2e-41
Smith-Waterman score: 2420; 98.9% identity (99.5% similar) in 376 aa overlap (1-375:1-376)
10 20 30 40 50 60
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 YYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNLERRGRQLGEPEKSQDSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLLKNYSLLKE
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 RKFLSLASNPEL-LNLPSSVIKKKVHFSGESKENIMRSENSESQLTSKSKCKDLKKRLHA
:::::::::: . .::
NP_001 RKFLSLASNPGMRINLVNRSWCYK
370 380
>>XP_011533370 (OMIM: 616731) PREDICTED: serine/threonin (483 aa)
initn: 628 init1: 378 opt: 686 Z-score: 268.4 bits: 59.0 E(85289): 3.3e-08
Smith-Waterman score: 686; 37.9% identity (69.4% similar) in 317 aa overlap (6-314:74-379)
10 20 30
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILV
. :.:. .:: :..:. . :::.: :
XP_011 SVATKKVICLCLGKAGRKVLAKKLSPLETMDKYDVIKAIGQGAFGKAYLAKGKSDSKHCV
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB6 WKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLA
::... .: ::. .:: ::...:::::: ... . . : :.::::::.::::
XP_011 IKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSF--QENGRLFIVMEYCDGGDLM
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB6 SVITKGTKERQYL-DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQN
. : ...: : .:. .: ..:..:.::. : :. .::::.: :.::. .
XP_011 KRI---NRQRGVLFSEDQILGWFVQISLGLKHIHDRK-----ILHRDIKAQNIFLSKNGM
170 180 190 200 210
160 170 180 190 200 210
pF1KB6 V-KLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALM
: ::::::.::.::.. .:.: .:::::.::: . ::.:.:::::::.:::::.:
XP_011 VAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLK
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB6 PPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILENPLIAD
:: . . ..:. :: ...: : .: ::. .:....... :::.. ::. :.. .
XP_011 HPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLEN
280 290 300 310 320 330
280 290 300 310 320
pF1KB6 LVADEQRRNL--ERRGRQL----GEPEKSQDSSPVLSELKLKEIQLQERERALKAREERL
:. .. :. ...: : : :. .. :... :......:
XP_011 LIPKYLTPEVIQEEFSHMLICRAGAPA-SRHAGKVVQKCKIQKVRFQGKCPPRSRISVPI
340 350 360 370 380 390
330 340 350 360 370 380
pF1KB6 EQKEQELCVRERLAEDKLARAENLLKNYSLLKERKFLSLASNPELLNLPSSVIKKKVHFS
XP_011 KRNAILHRNEWRPPAGAQKARSIKMIERPKIAAVCGHYDYYYAQLDMLRRRAHKPSYHPI
400 410 420 430 440 450
>>XP_006719871 (OMIM: 616731) PREDICTED: serine/threonin (598 aa)
initn: 628 init1: 378 opt: 686 Z-score: 267.2 bits: 59.0 E(85289): 3.8e-08
Smith-Waterman score: 686; 37.9% identity (69.4% similar) in 317 aa overlap (6-314:74-379)
10 20 30
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILV
. :.:. .:: :..:. . :::.: :
XP_006 SVATKKVICLCLGKAGRKVLAKKLSPLETMDKYDVIKAIGQGAFGKAYLAKGKSDSKHCV
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB6 WKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLA
::... .: ::. .:: ::...:::::: ... . . : :.::::::.::::
XP_006 IKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSF--QENGRLFIVMEYCDGGDLM
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB6 SVITKGTKERQYL-DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQN
. : ...: : .:. .: ..:..:.::. : :. .::::.: :.::. .
XP_006 KRI---NRQRGVLFSEDQILGWFVQISLGLKHIHDRK-----ILHRDIKAQNIFLSKNGM
170 180 190 200 210
160 170 180 190 200 210
pF1KB6 V-KLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALM
: ::::::.::.::.. .:.: .:::::.::: . ::.:.:::::::.:::::.:
XP_006 VAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLK
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB6 PPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILENPLIAD
:: . . ..:. :: ...: : .: ::. .:....... :::.. ::. :.. .
XP_006 HPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLEN
280 290 300 310 320 330
280 290 300 310 320
pF1KB6 LVADEQRRNL--ERRGRQL----GEPEKSQDSSPVLSELKLKEIQLQERERALKAREERL
:. .. :. ...: : : :. .. :... :......:
XP_006 LIPKYLTPEVIQEEFSHMLICRAGAPA-SRHAGKVVQKCKIQKVRFQGKCPPRSRISVPI
340 350 360 370 380 390
330 340 350 360 370 380
pF1KB6 EQKEQELCVRERLAEDKLARAENLLKNYSLLKERKFLSLASNPELLNLPSSVIKKKVHFS
XP_006 KRNAILHRNEWRPPAGAQKARSIKMIERPKIAAVCGHYDYYYAQLDMLRRRAHKPSYHPI
400 410 420 430 440 450
>>XP_011533368 (OMIM: 616731) PREDICTED: serine/threonin (697 aa)
initn: 628 init1: 378 opt: 686 Z-score: 266.4 bits: 59.1 E(85289): 4.3e-08
Smith-Waterman score: 686; 37.9% identity (69.4% similar) in 317 aa overlap (6-314:74-379)
10 20 30
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILV
. :.:. .:: :..:. . :::.: :
XP_011 SVATKKVICLCLGKAGRKVLAKKLSPLETMDKYDVIKAIGQGAFGKAYLAKGKSDSKHCV
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB6 WKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLA
::... .: ::. .:: ::...:::::: ... . . : :.::::::.::::
XP_011 IKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSF--QENGRLFIVMEYCDGGDLM
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB6 SVITKGTKERQYL-DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQN
. : ...: : .:. .: ..:..:.::. : :. .::::.: :.::. .
XP_011 KRI---NRQRGVLFSEDQILGWFVQISLGLKHIHDRK-----ILHRDIKAQNIFLSKNGM
170 180 190 200 210
160 170 180 190 200 210
pF1KB6 V-KLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALM
: ::::::.::.::.. .:.: .:::::.::: . ::.:.:::::::.:::::.:
XP_011 VAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLK
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB6 PPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILENPLIAD
:: . . ..:. :: ...: : .: ::. .:....... :::.. ::. :.. .
XP_011 HPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLEN
280 290 300 310 320 330
280 290 300 310 320
pF1KB6 LVADEQRRNL--ERRGRQL----GEPEKSQDSSPVLSELKLKEIQLQERERALKAREERL
:. .. :. ...: : : :. .. :... :......:
XP_011 LIPKYLTPEVIQEEFSHMLICRAGAPA-SRHAGKVVQKCKIQKVRFQGKCPPRSRISVPI
340 350 360 370 380 390
330 340 350 360 370 380
pF1KB6 EQKEQELCVRERLAEDKLARAENLLKNYSLLKERKFLSLASNPELLNLPSSVIKKKVHFS
XP_011 KRNAILHRNEWRPPAGAQKARSIKMIERPKIAAVCGHYDYYYAQLDMLRRRAHKPSYHPI
400 410 420 430 440 450
>>NP_954983 (OMIM: 616731) serine/threonine-protein kina (708 aa)
initn: 628 init1: 378 opt: 686 Z-score: 266.3 bits: 59.1 E(85289): 4.3e-08
Smith-Waterman score: 686; 37.9% identity (69.4% similar) in 317 aa overlap (6-314:2-307)
10 20 30 40 50 60
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEVNLLR
. :.:. .:: :..:. . :::.: : ::... .: ::. .:: ::.
NP_954 MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLE
10 20 30 40 50
70 80 90 100 110
pF1KB6 ELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL-DEEFVLRVMTQ
..:::::: ... . . : :.::::::.:::: . : ...: : .:. .: ..:
NP_954 KMKHPNIVAFFNSF--QENGRLFIVMEYCDGGDLMKRI---NRQRGVLFSEDQILGWFVQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNV-KLGDFGLARILNHDTSFAKTFVG
..:.::. : :. .::::.: :.::. . : ::::::.::.::.. .:.: .:
NP_954 ISLGLKHIHDRK-----ILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIG
120 130 140 150 160
180 190 200 210 220 230
pF1KB6 TPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPY
::::.::: . ::.:.:::::::.:::::.: :: . . ..:. :: ...: :
NP_954 TPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 RYSDELNEIITRMLNLKDYHRPSVEEILENPLIADLVADEQRRNL--ERRGRQL----GE
.: ::. .:....... :::.. ::. :.. .:. .. :. ...: :
NP_954 GFSRELHSLISQLFQVSPRDRPSINSILKRPFLENLIPKYLTPEVIQEEFSHMLICRAGA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB6 PEKSQDSSPVLSELKLKEIQLQERERALKAREERLEQKEQELCVRERLAEDKLARAENLL
: :. .. :... :......:
NP_954 PA-SRHAGKVVQKCKIQKVRFQGKCPPRSRISVPIKRNAILHRNEWRPPAGAQKARSIKM
290 300 310 320 330 340
>>XP_016876045 (OMIM: 616731) PREDICTED: serine/threonin (737 aa)
initn: 628 init1: 378 opt: 686 Z-score: 266.0 bits: 59.1 E(85289): 4.4e-08
Smith-Waterman score: 686; 37.9% identity (69.4% similar) in 317 aa overlap (6-314:74-379)
10 20 30
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILV
. :.:. .:: :..:. . :::.: :
XP_016 SVATKKVICLCLGKAGRKVLAKKLSPLETMDKYDVIKAIGQGAFGKAYLAKGKSDSKHCV
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB6 WKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLA
::... .: ::. .:: ::...:::::: ... . . : :.::::::.::::
XP_016 IKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSF--QENGRLFIVMEYCDGGDLM
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB6 SVITKGTKERQYL-DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQN
. : ...: : .:. .: ..:..:.::. : :. .::::.: :.::. .
XP_016 KRI---NRQRGVLFSEDQILGWFVQISLGLKHIHDRK-----ILHRDIKAQNIFLSKNGM
170 180 190 200 210
160 170 180 190 200 210
pF1KB6 V-KLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALM
: ::::::.::.::.. .:.: .:::::.::: . ::.:.:::::::.:::::.:
XP_016 VAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLK
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB6 PPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILENPLIAD
:: . . ..:. :: ...: : .: ::. .:....... :::.. ::. :.. .
XP_016 HPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLEN
280 290 300 310 320 330
280 290 300 310 320
pF1KB6 LVADEQRRNL--ERRGRQL----GEPEKSQDSSPVLSELKLKEIQLQERERALKAREERL
:. .. :. ...: : : :. .. :... :......:
XP_016 LIPKYLTPEVIQEEFSHMLICRAGAPA-SRHAGKVVQKCKIQKVRFQGKCPPRSRISVPI
340 350 360 370 380 390
330 340 350 360 370 380
pF1KB6 EQKEQELCVRERLAEDKLARAENLLKNYSLLKERKFLSLASNPELLNLPSSVIKKKVHFS
XP_016 KRNAILHRNEWRPPAGAQKARSIKMIERPKIAAVCGHYDYYYAQLDMLRRRAHKPSYHPI
400 410 420 430 440 450
>>XP_016876044 (OMIM: 616731) PREDICTED: serine/threonin (755 aa)
initn: 628 init1: 378 opt: 686 Z-score: 265.9 bits: 59.1 E(85289): 4.5e-08
Smith-Waterman score: 686; 37.9% identity (69.4% similar) in 317 aa overlap (6-314:74-379)
10 20 30
pF1KB6 MPSRAEDYEVLYTIGTGSYGRCQKIRRKSDGKILV
. :.:. .:: :..:. . :::.: :
XP_016 SVATKKVICLCLGKAGRKVLAKKLSPLETMDKYDVIKAIGQGAFGKAYLAKGKSDSKHCV
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB6 WKELDYGSMTEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLA
::... .: ::. .:: ::...:::::: ... . . : :.::::::.::::
XP_016 IKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSF--QENGRLFIVMEYCDGGDLM
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB6 SVITKGTKERQYL-DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQN
. : ...: : .:. .: ..:..:.::. : :. .::::.: :.::. .
XP_016 KRI---NRQRGVLFSEDQILGWFVQISLGLKHIHDRK-----ILHRDIKAQNIFLSKNGM
170 180 190 200 210
160 170 180 190 200 210
pF1KB6 V-KLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALM
: ::::::.::.::.. .:.: .:::::.::: . ::.:.:::::::.:::::.:
XP_016 VAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLK
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB6 PPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILENPLIAD
:: . . ..:. :: ...: : .: ::. .:....... :::.. ::. :.. .
XP_016 HPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLEN
280 290 300 310 320 330
280 290 300 310 320
pF1KB6 LVADEQRRNL--ERRGRQL----GEPEKSQDSSPVLSELKLKEIQLQERERALKAREERL
:. .. :. ...: : : :. .. :... :......:
XP_016 LIPKYLTPEVIQEEFSHMLICRAGAPA-SRHAGKVVQKCKIQKVRFQGKCPPRSRISVPI
340 350 360 370 380 390
330 340 350 360 370 380
pF1KB6 EQKEQELCVRERLAEDKLARAENLLKNYSLLKERKFLSLASNPELLNLPSSVIKKKVHFS
XP_016 KRNAILHRNEWRPPAGAQKARSIKMIERPKIAAVCGHYDYYYAQLDMLRRRAHKPSYHPI
400 410 420 430 440 450
445 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:15:25 2016 done: Sat Nov 5 11:15:27 2016
Total Scan time: 9.440 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]