FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6650, 446 aa 1>>>pF1KB6650 446 - 446 aa - 446 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.7013+/-0.00137; mu= -16.2660+/- 0.081 mean_var=447.6417+/-94.281, 0's: 0 Z-trim(110.1): 23 B-trim: 108 in 1/52 Lambda= 0.060619 statistics sampled from 11337 (11350) to 11337 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.349), width: 16 Scan time: 2.950 The best scores are: opt bits E(32554) CCDS11538.1 CALCOCO2 gene_id:10241|Hs108|chr17 ( 446) 3011 277.9 1.4e-74 CCDS58559.1 CALCOCO2 gene_id:10241|Hs108|chr17 ( 470) 2582 240.4 2.9e-63 CCDS58558.1 CALCOCO2 gene_id:10241|Hs108|chr17 ( 467) 2581 240.3 3e-63 CCDS58561.1 CALCOCO2 gene_id:10241|Hs108|chr17 ( 374) 2494 232.7 5e-61 CCDS58560.1 CALCOCO2 gene_id:10241|Hs108|chr17 ( 404) 1769 169.3 6.5e-42 >>CCDS11538.1 CALCOCO2 gene_id:10241|Hs108|chr17 (446 aa) initn: 3011 init1: 3011 opt: 3011 Z-score: 1452.4 bits: 277.9 E(32554): 1.4e-74 Smith-Waterman score: 3011; 100.0% identity (100.0% similar) in 446 aa overlap (1-446:1-446) 10 20 30 40 50 60 pF1KB6 MEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 IPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 QEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 EKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 QELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLKRENSRLLSYMGLDFNSLPYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLKRENSRLLSYMGLDFNSLPYQV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 PTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKKCPICKADDICDHTLEQQQMQPLCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKKCPICKADDICDHTLEQQQMQPLCF 370 380 390 400 410 420 430 440 pF1KB6 NCPICDKIFPATEKQIFEDHVFCHSL :::::::::::::::::::::::::: CCDS11 NCPICDKIFPATEKQIFEDHVFCHSL 430 440 >>CCDS58559.1 CALCOCO2 gene_id:10241|Hs108|chr17 (470 aa) initn: 2582 init1: 2582 opt: 2582 Z-score: 1249.3 bits: 240.4 E(32554): 2.9e-63 Smith-Waterman score: 2953; 94.9% identity (94.9% similar) in 470 aa overlap (1-446:1-470) 10 20 30 40 50 60 pF1KB6 MEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFR 10 20 30 40 50 60 70 80 90 pF1KB6 ------------------------VGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAY :::::::::::::::::::::::::::::::::::: CCDS58 AFKCFQDKLEQELLKWRSQGQKLQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAY 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 YLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKEN 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 QELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQN 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 QKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQR 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 KDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGEND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGEND 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 LLKRENSRLLSYMGLDFNSLPYQVPTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LLKRENSRLLSYMGLDFNSLPYQVPTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKK 370 380 390 400 410 420 400 410 420 430 440 pF1KB6 CPICKADDICDHTLEQQQMQPLCFNCPICDKIFPATEKQIFEDHVFCHSL :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CPICKADDICDHTLEQQQMQPLCFNCPICDKIFPATEKQIFEDHVFCHSL 430 440 450 460 470 >>CCDS58558.1 CALCOCO2 gene_id:10241|Hs108|chr17 (467 aa) initn: 2581 init1: 2581 opt: 2581 Z-score: 1248.9 bits: 240.3 E(32554): 3e-63 Smith-Waterman score: 2959; 95.5% identity (95.5% similar) in 467 aa overlap (1-446:1-467) 10 20 30 40 50 60 pF1KB6 MEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFR 10 20 30 40 50 60 70 80 90 pF1KB6 ---------------------VGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLP ::::::::::::::::::::::::::::::::::::::: CCDS58 CSLNQTIQLLITPDTGSIWHQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 KDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQEL 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 KDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKM 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 SSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 KKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLK 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 RENSRLLSYMGLDFNSLPYQVPTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKKCPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RENSRLLSYMGLDFNSLPYQVPTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKKCPI 370 380 390 400 410 420 400 410 420 430 440 pF1KB6 CKADDICDHTLEQQQMQPLCFNCPICDKIFPATEKQIFEDHVFCHSL ::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CKADDICDHTLEQQQMQPLCFNCPICDKIFPATEKQIFEDHVFCHSL 430 440 450 460 >>CCDS58561.1 CALCOCO2 gene_id:10241|Hs108|chr17 (374 aa) initn: 2494 init1: 2494 opt: 2494 Z-score: 1209.1 bits: 232.7 E(32554): 5e-61 Smith-Waterman score: 2494; 100.0% identity (100.0% similar) in 374 aa overlap (73-446:1-374) 50 60 70 80 90 100 pF1KB6 TFTQHFIPRRKDWIGIFRVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDD :::::::::::::::::::::::::::::: CCDS58 MWVTLPIDLNNKSAKQQEVQFKAYYLPKDD 10 20 30 110 120 130 140 150 160 pF1KB6 EYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 CISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSE 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 NEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 EQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLKREN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLKREN 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB6 SRLLSYMGLDFNSLPYQVPTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKKCPICKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SRLLSYMGLDFNSLPYQVPTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKKCPICKA 280 290 300 310 320 330 410 420 430 440 pF1KB6 DDICDHTLEQQQMQPLCFNCPICDKIFPATEKQIFEDHVFCHSL :::::::::::::::::::::::::::::::::::::::::::: CCDS58 DDICDHTLEQQQMQPLCFNCPICDKIFPATEKQIFEDHVFCHSL 340 350 360 370 >>CCDS58560.1 CALCOCO2 gene_id:10241|Hs108|chr17 (404 aa) initn: 1767 init1: 1767 opt: 1769 Z-score: 866.0 bits: 169.3 E(32554): 6.5e-42 Smith-Waterman score: 2641; 90.6% identity (90.6% similar) in 446 aa overlap (1-446:1-404) 10 20 30 40 50 60 pF1KB6 MEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 IPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKK ::::::::::::::::::: CCDS58 IPFQFRPENEEDILVVTTQ----------------------------------------- 130 190 200 210 220 230 240 pF1KB6 QEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 -EELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQ 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB6 EKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQ 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB6 QELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLKRENSRLLSYMGLDFNSLPYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QELMDENFDLSKRLSENEIICNALQRQKERLEGENDLLKRENSRLLSYMGLDFNSLPYQV 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB6 PTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKKCPICKADDICDHTLEQQQMQPLCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PTSDEGGARQNPGLAYGNPYSGIQESSSPSPLSIKKCPICKADDICDHTLEQQQMQPLCF 320 330 340 350 360 370 430 440 pF1KB6 NCPICDKIFPATEKQIFEDHVFCHSL :::::::::::::::::::::::::: CCDS58 NCPICDKIFPATEKQIFEDHVFCHSL 380 390 400 446 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:16:04 2016 done: Sat Nov 5 11:16:04 2016 Total Scan time: 2.950 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]