FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6654, 389 aa
1>>>pF1KB6654 389 - 389 aa - 389 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9569+/-0.000407; mu= 13.2207+/- 0.025
mean_var=66.6928+/-13.579, 0's: 0 Z-trim(111.4): 23 B-trim: 674 in 1/54
Lambda= 0.157049
statistics sampled from 19940 (19960) to 19940 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.234), width: 16
Scan time: 6.810
The best scores are: opt bits E(85289)
NP_001025 (OMIM: 180390) ribonucleoside-diphosphat ( 389) 2584 594.6 1.4e-169
NP_001159403 (OMIM: 180390) ribonucleoside-diphosp ( 449) 2584 594.6 1.5e-169
NP_056528 (OMIM: 604712,612075,613077) ribonucleos ( 351) 1861 430.7 2.5e-120
NP_001165948 (OMIM: 604712,612075,613077) ribonucl ( 423) 1861 430.8 3e-120
NP_001165949 (OMIM: 604712,612075,613077) ribonucl ( 299) 1662 385.6 8.1e-107
>>NP_001025 (OMIM: 180390) ribonucleoside-diphosphate re (389 aa)
initn: 2584 init1: 2584 opt: 2584 Z-score: 3165.8 bits: 594.6 E(85289): 1.4e-169
Smith-Waterman score: 2584; 100.0% identity (100.0% similar) in 389 aa overlap (1-389:1-389)
10 20 30 40 50 60
pF1KB6 MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 DTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 ASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 QEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTN
310 320 330 340 350 360
370 380
pF1KB6 FFEKRVGEYQRMGVMSSPTENSFTLDADF
:::::::::::::::::::::::::::::
NP_001 FFEKRVGEYQRMGVMSSPTENSFTLDADF
370 380
>>NP_001159403 (OMIM: 180390) ribonucleoside-diphosphate (449 aa)
initn: 2584 init1: 2584 opt: 2584 Z-score: 3164.7 bits: 594.6 E(85289): 1.5e-169
Smith-Waterman score: 2584; 100.0% identity (100.0% similar) in 389 aa overlap (1-389:61-449)
10 20 30
pF1KB6 MLSLRVPLAPITDPQQLQLSPLKGLSLVDK
::::::::::::::::::::::::::::::
NP_001 FKGCWSEGSPVHPVPAVLSWLLALLRCASTMLSLRVPLAPITDPQQLQLSPLKGLSLVDK
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB6 ENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDI
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB6 WQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFS
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB6 QEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWA
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB6 LRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHC
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB6 DFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADR
340 350 360 370 380 390
340 350 360 370 380
pF1KB6 LMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF
400 410 420 430 440
>>NP_056528 (OMIM: 604712,612075,613077) ribonucleoside- (351 aa)
initn: 1861 init1: 1861 opt: 1861 Z-score: 2281.2 bits: 430.7 E(85289): 2.5e-120
Smith-Waterman score: 1861; 83.8% identity (96.3% similar) in 321 aa overlap (69-389:31-351)
40 50 60 70 80 90
pF1KB6 GTRVLASKTARRIFQEPTEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAE
.:::::.. ::::::::.: :::.:::.:.
NP_056 MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQ
10 20 30 40 50 60
100 110 120 130 140 150
pF1KB6 ASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEA
::::::::::::::. ::..:: .:.:::::.::::::::::::::::::::::::. ::
NP_056 ASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEA
70 80 90 100 110 120
160 170 180 190 200 210
pF1KB6 RCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKE
:::::::: .::.:::::::::::::.:::.:::::::::::: ::::::::::::.:..
NP_056 RCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRK
130 140 150 160 170 180
220 230 240 250 260 270
pF1KB6 ATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFK
.:.::::::::::::.:::::::.:::::::::::::::::::::::::::::::::::.
NP_056 STFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQ
190 200 210 220 230 240
280 290 300 310 320 330
pF1KB6 HLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFS
.::.:::::::::::..::.:::::::::::: :::::: :::::::::::::..:::::
NP_056 YLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFS
250 260 270 280 290 300
340 350 360 370 380
pF1KB6 KVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF
:::..:::::::::::::::::::::::.::::..::. :.: :::::::
NP_056 KVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
310 320 330 340 350
>>NP_001165948 (OMIM: 604712,612075,613077) ribonucleosi (423 aa)
initn: 1861 init1: 1861 opt: 1861 Z-score: 2279.8 bits: 430.8 E(85289): 3e-120
Smith-Waterman score: 1861; 83.8% identity (96.3% similar) in 321 aa overlap (69-389:103-423)
40 50 60 70 80 90
pF1KB6 GTRVLASKTARRIFQEPTEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAE
.:::::.. ::::::::.: :::.:::.:.
NP_001 SAPGPAKDDAWRPQAGRSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQ
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB6 ASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEA
::::::::::::::. ::..:: .:.:::::.::::::::::::::::::::::::. ::
NP_001 ASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEA
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB6 RCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKE
:::::::: .::.:::::::::::::.:::.:::::::::::: ::::::::::::.:..
NP_001 RCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRK
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB6 ATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFK
.:.::::::::::::.:::::::.:::::::::::::::::::::::::::::::::::.
NP_001 STFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQ
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB6 HLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFS
.::.:::::::::::..::.:::::::::::: :::::: :::::::::::::..:::::
NP_001 YLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFS
320 330 340 350 360 370
340 350 360 370 380
pF1KB6 KVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF
:::..:::::::::::::::::::::::.::::..::. :.: :::::::
NP_001 KVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
380 390 400 410 420
>>NP_001165949 (OMIM: 604712,612075,613077) ribonucleosi (299 aa)
initn: 1662 init1: 1662 opt: 1662 Z-score: 2038.7 bits: 385.6 E(85289): 8.1e-107
Smith-Waterman score: 1662; 82.4% identity (94.9% similar) in 295 aa overlap (95-389:5-299)
70 80 90 100 110 120
pF1KB6 PGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEER
.. ::. .:::::::. ::..:: .:.
NP_001 MGDPERPEAAGLDQDEVDLSKDLPHWNKLKADEK
10 20 30
130 140 150 160 170 180
pF1KB6 YFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYI
:::::.::::::::::::::::::::::::. :::::::::: .::.:::::::::::::
NP_001 YFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYI
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB6 KDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIF
.:::.:::::::::::: ::::::::::::.:...:.::::::::::::.:::::::.::
NP_001 RDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIF
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB6 WLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFL
:::::::::::::::::::::::::::::::::..::.:::::::::::..::.::::::
NP_001 WLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB6 TEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEK
:::::: :::::: :::::::::::::..::::::::..:::::::::::::::::::::
NP_001 TEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEK
220 230 240 250 260 270
370 380
pF1KB6 RVGEYQRMGVMSSPTENSFTLDADF
::.::::..::. :.: :::::::
NP_001 RVSEYQRFAVMAETTDNVFTLDADF
280 290
389 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:32:38 2016 done: Sat Nov 5 07:32:39 2016
Total Scan time: 6.810 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]