FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6660, 451 aa 1>>>pF1KB6660 451 - 451 aa - 451 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2059+/-0.000846; mu= 14.1574+/- 0.051 mean_var=88.8763+/-17.859, 0's: 0 Z-trim(108.3): 12 B-trim: 0 in 0/51 Lambda= 0.136045 statistics sampled from 10120 (10124) to 10120 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.311), width: 16 Scan time: 2.110 The best scores are: opt bits E(32554) CCDS34736.1 IFRD1 gene_id:3475|Hs108|chr7 ( 451) 2957 590.3 1.3e-168 CCDS56504.1 IFRD1 gene_id:3475|Hs108|chr7 ( 401) 2626 525.3 4.3e-149 CCDS77746.1 IFRD2 gene_id:7866|Hs108|chr3 ( 506) 1433 291.2 1.6e-78 >>CCDS34736.1 IFRD1 gene_id:3475|Hs108|chr7 (451 aa) initn: 2957 init1: 2957 opt: 2957 Z-score: 3140.5 bits: 590.3 E(32554): 1.3e-168 Smith-Waterman score: 2957; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB6 MPKNKKRNTPHRGSSAGGGGSGAAAATAATAGGQHRNVQPFSDEDASIETMSHCSGYSDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MPKNKKRNTPHRGSSAGGGGSGAAAATAATAGGQHRNVQPFSDEDASIETMSHCSGYSDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGIKNALASKMLYEFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGIKNALASKMLYEFIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ERRMTLTDSIERCLKKGKSDEQRAAAALASVLCIQLGPGIESEEILKTLGPILKKIICDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ERRMTLTDSIERCLKKGKSDEQRAAAALASVLCIQLGPGIESEEILKTLGPILKKIICDG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SASMQARQTCATCFGVCCFIATDDITELYSTLECLENIFTKSYLKEKDTTVICSTPNTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SASMQARQTCATCFGVCCFIATDDITELYSTLECLENIFTKSYLKEKDTTVICSTPNTVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 HISSLLAWTLLLTICPINEVKKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 HISSLLAWTLLLTICPINEVKKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARGI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 ESDFFYEDMESLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETIKFGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ESDFFYEDMESLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETIKFGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 ERMYIDCWVKKHTYDTFKEVLGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ERMYIDCWVKKHTYDTFKEVLGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRF 370 380 390 400 410 420 430 440 450 pF1KB6 ERHLYNSAAFKARTKARSKCRDKRADVGEFF ::::::::::::::::::::::::::::::: CCDS34 ERHLYNSAAFKARTKARSKCRDKRADVGEFF 430 440 450 >>CCDS56504.1 IFRD1 gene_id:3475|Hs108|chr7 (401 aa) initn: 2626 init1: 2626 opt: 2626 Z-score: 2790.1 bits: 525.3 E(32554): 4.3e-149 Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 401 aa overlap (51-451:1-401) 30 40 50 60 70 80 pF1KB6 SGAAAATAATAGGQHRNVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDL :::::::::::::::::::::::::::::: CCDS56 MSHCSGYSDPSSFAEDGPEVLDEEGTQEDL 10 20 30 90 100 110 120 130 140 pF1KB6 EYKLKGLIDLTLDKSAKTRQAALEGIKNALASKMLYEFILERRMTLTDSIERCLKKGKSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EYKLKGLIDLTLDKSAKTRQAALEGIKNALASKMLYEFILERRMTLTDSIERCLKKGKSD 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 EQRAAAALASVLCIQLGPGIESEEILKTLGPILKKIICDGSASMQARQTCATCFGVCCFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EQRAAAALASVLCIQLGPGIESEEILKTLGPILKKIICDGSASMQARQTCATCFGVCCFI 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 ATDDITELYSTLECLENIFTKSYLKEKDTTVICSTPNTVLHISSLLAWTLLLTICPINEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ATDDITELYSTLECLENIFTKSYLKEKDTTVICSTPNTVLHISSLLAWTLLLTICPINEV 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 KKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARGIESDFFYEDMESLTQMLRALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 KKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARGIESDFFYEDMESLTQMLRALA 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB6 TDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETIKFGPERMYIDCWVKKHTYDTFKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 TDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETIKFGPERMYIDCWVKKHTYDTFKEV 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB6 LGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 LGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKC 340 350 360 370 380 390 450 pF1KB6 RDKRADVGEFF ::::::::::: CCDS56 RDKRADVGEFF 400 >>CCDS77746.1 IFRD2 gene_id:7866|Hs108|chr3 (506 aa) initn: 1422 init1: 816 opt: 1433 Z-score: 1523.1 bits: 291.2 E(32554): 1.6e-78 Smith-Waterman score: 1433; 50.6% identity (78.1% similar) in 453 aa overlap (1-447:65-505) 10 20 30 pF1KB6 MPKNKKRNTPHRGSSAGGGGSGAAAATAAT ::. .: :: ..:.. ::: : ... : CCDS77 SAQRTGRRLVGLEPTPTGSLTPRPPRPVPGMPRARKGNTLRKGGQRRGGG--ARSSAQAD 40 50 60 70 80 90 40 50 60 70 80 pF1KB6 AGGQHRNVQPFSDEDASIE---TMSHCSGYSDPSSFAED--GPEVLDEEGTQEDLEYKLK .:. ::..:. : : :.: : :. ::: : .:.::.: ::::: ::: CCDS77 SGS--------SDDEAASEARSTASECP--SLLSTTAEDSLGGDVVDEQGQQEDLEEKLK 100 110 120 130 140 90 100 110 120 130 140 pF1KB6 GLIDLTLDKSAKTRQAALEGIKNALASKMLYEFILERRMTLTDSIERCLKKGKSDEQRAA .: ::::::::.:::... ::::..: .:.::::.::.:..:.::::::..:: : CCDS77 EYVDCLTDKSAKTRQGALESLRLALASRLLPDFLLERRLTLADALEKCLKKGKGEEQALA 150 160 170 180 190 200 150 160 170 180 190 200 pF1KB6 AALASVLCIQLGPGIESEEILKTLGPILKKIICDGSASMQARQTCATCFGVCCFIATDDI ::. ..::.::::: ..::....: :.: ... :..:: :: ::. .:. :..:. :: CCDS77 AAVLGLLCVQLGPGPKGEELFHSLQPLLVSVLSDSTASPAARLHCASALGLGCYVAAADI 210 220 230 240 250 260 210 220 230 240 250 260 pF1KB6 TELYSTLECLENIFTKSY-LKEKDTTVICSTPNTVLHISSLLAWTLLLTICPINEVKKKL .: : : :::..:.. : : ..:. . . : ..: ::.::::::: ..... : CCDS77 QDLVSCLACLESVFSRFYGLGGSSTSPVVPASLHGLLSAALQAWALLLTICPSTQISHIL 270 280 290 300 310 320 270 280 290 300 310 320 pF1KB6 EMHFHKLPSLLSCDDVNMRIAAGESLALLFELARGIESDFFYEDMESLTQMLRALATDGN . .. .::.::: ..::.::::::..:::::::: .: .: :::::.: ..::.::::.: CCDS77 DRQLPRLPQLLSSESVNLRIAAGETIALLFELARDLEEEFVYEDMEALCSVLRTLATDSN 330 340 350 360 370 380 330 340 350 360 370 380 pF1KB6 KHRAKVDKRKQRSVFRDVLRAVEERDFPTETIKFGPERMYIDCWVKKHTYDTFKEVLGSG :.:::.:.:.:::.:: ::..:: . : ..:: : .:.: :.... : .:::::::: CCDS77 KYRAKADRRRQRSTFRAVLHSVEGGECEEEIVRFGFEVLYMDSWARHRIYAAFKEVLGSG 390 400 410 420 430 440 390 400 410 420 430 440 pF1KB6 MQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKCRDKR :..:::.::.::..: ::: ..:::..::. :. :::.::::.:::::::::::. :::: CCDS77 MHHHLQNNELLRDIFGLGPVLLLDATALKACKVPRFEKHLYNAAAFKARTKARSRVRDKR 450 460 470 480 490 500 450 pF1KB6 ADVGEFF ::. CCDS77 ADIL 451 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:18:26 2016 done: Sat Nov 5 11:18:27 2016 Total Scan time: 2.110 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]