FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6665, 424 aa 1>>>pF1KB6665 424 - 424 aa - 424 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5271+/-0.000376; mu= 4.0177+/- 0.023 mean_var=268.6070+/-57.253, 0's: 0 Z-trim(121.2): 93 B-trim: 40 in 1/58 Lambda= 0.078256 statistics sampled from 37412 (37552) to 37412 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.44), width: 16 Scan time: 7.640 The best scores are: opt bits E(85289) NP_001171904 (OMIM: 606513) protein kinase C and c ( 424) 2898 340.4 5.3e-93 NP_057307 (OMIM: 606513) protein kinase C and case ( 424) 2898 340.4 5.3e-93 NP_001171903 (OMIM: 606513) protein kinase C and c ( 424) 2898 340.4 5.3e-93 XP_005261376 (OMIM: 604960) PREDICTED: protein kin ( 445) 1432 174.9 3.6e-43 NP_001171900 (OMIM: 604960) protein kinase C and c ( 445) 1432 174.9 3.6e-43 XP_016884054 (OMIM: 604960) PREDICTED: protein kin ( 447) 1418 173.3 1.1e-42 XP_011528155 (OMIM: 604960) PREDICTED: protein kin ( 447) 1418 173.3 1.1e-42 XP_016884055 (OMIM: 604960) PREDICTED: protein kin ( 447) 1418 173.3 1.1e-42 XP_016884056 (OMIM: 604960) PREDICTED: protein kin ( 447) 1418 173.3 1.1e-42 NP_009160 (OMIM: 604960) protein kinase C and case ( 486) 1407 172.1 2.7e-42 NP_001171899 (OMIM: 604960) protein kinase C and c ( 486) 1407 172.1 2.7e-42 XP_016884053 (OMIM: 604960) PREDICTED: protein kin ( 486) 1407 172.1 2.7e-42 XP_011528150 (OMIM: 604960) PREDICTED: protein kin ( 488) 1393 170.5 8.2e-42 XP_011528149 (OMIM: 604960) PREDICTED: protein kin ( 488) 1393 170.5 8.2e-42 XP_016884052 (OMIM: 604960) PREDICTED: protein kin ( 488) 1393 170.5 8.2e-42 XP_016884051 (OMIM: 604960) PREDICTED: protein kin ( 488) 1393 170.5 8.2e-42 XP_011528153 (OMIM: 604960) PREDICTED: protein kin ( 488) 1393 170.5 8.2e-42 XP_011528148 (OMIM: 604960) PREDICTED: protein kin ( 488) 1393 170.5 8.2e-42 XP_011528152 (OMIM: 604960) PREDICTED: protein kin ( 488) 1393 170.5 8.2e-42 XP_011528151 (OMIM: 604960) PREDICTED: protein kin ( 488) 1393 170.5 8.2e-42 NP_065855 (OMIM: 606512) protein kinase C and case ( 444) 1318 162.0 2.7e-39 NP_001186512 (OMIM: 606512) protein kinase C and c ( 444) 1318 162.0 2.7e-39 XP_011512843 (OMIM: 606512) PREDICTED: protein kin ( 444) 1318 162.0 2.7e-39 XP_016884057 (OMIM: 604960) PREDICTED: protein kin ( 406) 1252 154.5 4.5e-37 XP_011528154 (OMIM: 604960) PREDICTED: protein kin ( 447) 1227 151.7 3.4e-36 XP_011520469 (OMIM: 604416,606347) PREDICTED: prol ( 319) 264 42.9 0.0014 XP_011520468 (OMIM: 604416,606347) PREDICTED: prol ( 358) 264 42.9 0.0016 XP_011520465 (OMIM: 604416,606347) PREDICTED: prol ( 432) 264 43.0 0.0018 XP_011520470 (OMIM: 604416,606347) PREDICTED: prol ( 435) 264 43.0 0.0018 XP_011520471 (OMIM: 604416,606347) PREDICTED: prol ( 284) 248 41.0 0.0047 >>NP_001171904 (OMIM: 606513) protein kinase C and casei (424 aa) initn: 2898 init1: 2898 opt: 2898 Z-score: 1790.7 bits: 340.4 E(85289): 5.3e-93 Smith-Waterman score: 2898; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 FFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPPPQSPGSPGTGQDEEWSDEESPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPPPQSPGSPGTGQDEEWSDEESPR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 KAATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE 370 380 390 400 410 420 pF1KB6 CVGA :::: NP_001 CVGA >>NP_057307 (OMIM: 606513) protein kinase C and casein k (424 aa) initn: 2898 init1: 2898 opt: 2898 Z-score: 1790.7 bits: 340.4 E(85289): 5.3e-93 Smith-Waterman score: 2898; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 ARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 FFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 FFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPPPQSPGSPGTGQDEEWSDEESPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPPPQSPGSPGTGQDEEWSDEESPR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 KAATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KAATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE 370 380 390 400 410 420 pF1KB6 CVGA :::: NP_057 CVGA >>NP_001171903 (OMIM: 606513) protein kinase C and casei (424 aa) initn: 2898 init1: 2898 opt: 2898 Z-score: 1790.7 bits: 340.4 E(85289): 5.3e-93 Smith-Waterman score: 2898; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 FFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPPPQSPGSPGTGQDEEWSDEESPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPPPQSPGSPGTGQDEEWSDEESPR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 KAATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAATGVRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVE 370 380 390 400 410 420 pF1KB6 CVGA :::: NP_001 CVGA >>XP_005261376 (OMIM: 604960) PREDICTED: protein kinase (445 aa) initn: 1690 init1: 1367 opt: 1432 Z-score: 896.0 bits: 174.9 E(85289): 3.6e-43 Smith-Waterman score: 1694; 56.1% identity (81.4% similar) in 440 aa overlap (4-422:6-444) 10 20 30 40 50 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLA ....: :. . ::::.:::.:::.:..::::::.::..:..:::::::::::::. XP_005 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DWARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAF .:::.:: :::::::::.:::: ::.. :::.: :::::. .:...: :... ::. :: XP_005 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 HRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADS :. ..:::.:.. :::::::::::: :.::::::.::..::: :.:: : .::...::: XP_005 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVSQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQR ... :::.:::...:.: ... ::: .::..: :: . ::.:::.:::.:: :: :..: XP_005 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 LLFFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQ : ::...:: ...:::::. .. ...::.:.:.::. :::::.:..::::::::::: XP_005 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 FEEWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPP-PQSPGSPGTGQD--EEWSD ::::: : .::.::.:: .. : ::::.: : : . : :.: .: :. .::: XP_005 FEEWSADLNRTLSRREKK-KATDGVTLTGINQTGDQSLPSKPSSVSSYEKTQSYPTDWSD 310 320 330 340 350 360 370 380 390 pF1KB6 EES--PRK--------------AATG--VRVRALYDYAGQEADELSFRAGEELLKMSEED .:: : . :..: ::::::::: ::: :::::.::.:: :: .:: XP_005 DESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDED 360 370 380 390 400 410 400 410 420 pF1KB6 EQGWCQGQLQSGRIGLYPANYVECVGA :::::.:.:..:..::::::::: . XP_005 EQGWCKGRLDNGQVGLYPANYVEAIQ 420 430 440 >>NP_001171900 (OMIM: 604960) protein kinase C and casei (445 aa) initn: 1690 init1: 1367 opt: 1432 Z-score: 896.0 bits: 174.9 E(85289): 3.6e-43 Smith-Waterman score: 1694; 56.1% identity (81.4% similar) in 440 aa overlap (4-422:6-444) 10 20 30 40 50 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLA ....: :. . ::::.:::.:::.:..::::::.::..:..:::::::::::::. NP_001 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DWARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAF .:::.:: :::::::::.:::: ::.. :::.: :::::. .:...: :... ::. :: NP_001 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 HRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADS :. ..:::.:.. :::::::::::: :.::::::.::..::: :.:: : .::...::: NP_001 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVSQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQR ... :::.:::...:.: ... ::: .::..: :: . ::.:::.:::.:: :: :..: NP_001 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 LLFFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQ : ::...:: ...:::::. .. ...::.:.:.::. :::::.:..::::::::::: NP_001 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 FEEWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPP-PQSPGSPGTGQD--EEWSD ::::: : .::.::.:: .. : ::::.: : : . : :.: .: :. .::: NP_001 FEEWSADLNRTLSRREKK-KATDGVTLTGINQTGDQSLPSKPSSVSSYEKTQSYPTDWSD 310 320 330 340 350 360 370 380 390 pF1KB6 EES--PRK--------------AATG--VRVRALYDYAGQEADELSFRAGEELLKMSEED .:: : . :..: ::::::::: ::: :::::.::.:: :: .:: NP_001 DESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDED 360 370 380 390 400 410 400 410 420 pF1KB6 EQGWCQGQLQSGRIGLYPANYVECVGA :::::.:.:..:..::::::::: . NP_001 EQGWCKGRLDNGQVGLYPANYVEAIQ 420 430 440 >>XP_016884054 (OMIM: 604960) PREDICTED: protein kinase (447 aa) initn: 1610 init1: 1287 opt: 1418 Z-score: 887.4 bits: 173.3 E(85289): 1.1e-42 Smith-Waterman score: 1680; 55.9% identity (81.0% similar) in 442 aa overlap (4-422:6-446) 10 20 30 40 50 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLA ....: :. . ::::.:::.:::.:..::::::.::..:..:::::::::::::. XP_016 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DWARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAF .:::.:: :::::::::.:::: ::.. :::.: :::::. .:...: :... ::. :: XP_016 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 HRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADS :. ..:::.:.. :::::::::::: :.::::::.::..::: :.:: : .::...::: XP_016 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVSQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQR ... :::.:::...:.: ... ::: .::..: :: . ::.:::.:::.:: :: :..: XP_016 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 LLFFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQ : ::...:: ...:::::. .. ...::.:.:.::. :::::.:..::::::::::: XP_016 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 FE--EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPP-PQSPGSPGTGQD--EEW :: ::: : .::.::.:: .. : ::::.: : : . : :.: .: :. .: XP_016 FEDEEWSADLNRTLSRREKK-KATDGVTLTGINQTGDQSLPSKPSSVSSYEKTQSYPTDW 310 320 330 340 350 360 370 380 390 pF1KB6 SDEES--PRK--------------AATG--VRVRALYDYAGQEADELSFRAGEELLKMSE ::.:: : . :..: ::::::::: ::: :::::.::.:: :: . XP_016 SDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMED 360 370 380 390 400 410 400 410 420 pF1KB6 EDEQGWCQGQLQSGRIGLYPANYVECVGA :::::::.:.:..:..::::::::: . XP_016 EDEQGWCKGRLDNGQVGLYPANYVEAIQ 420 430 440 >>XP_011528155 (OMIM: 604960) PREDICTED: protein kinase (447 aa) initn: 1610 init1: 1287 opt: 1418 Z-score: 887.4 bits: 173.3 E(85289): 1.1e-42 Smith-Waterman score: 1680; 55.9% identity (81.0% similar) in 442 aa overlap (4-422:6-446) 10 20 30 40 50 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLA ....: :. . ::::.:::.:::.:..::::::.::..:..:::::::::::::. XP_011 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DWARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAF .:::.:: :::::::::.:::: ::.. :::.: :::::. .:...: :... ::. :: XP_011 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 HRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADS :. ..:::.:.. :::::::::::: :.::::::.::..::: :.:: : .::...::: XP_011 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVSQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQR ... :::.:::...:.: ... ::: .::..: :: . ::.:::.:::.:: :: :..: XP_011 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 LLFFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQ : ::...:: ...:::::. .. ...::.:.:.::. :::::.:..::::::::::: XP_011 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 FE--EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPP-PQSPGSPGTGQD--EEW :: ::: : .::.::.:: .. : ::::.: : : . : :.: .: :. .: XP_011 FEDEEWSADLNRTLSRREKK-KATDGVTLTGINQTGDQSLPSKPSSVSSYEKTQSYPTDW 310 320 330 340 350 360 370 380 390 pF1KB6 SDEES--PRK--------------AATG--VRVRALYDYAGQEADELSFRAGEELLKMSE ::.:: : . :..: ::::::::: ::: :::::.::.:: :: . XP_011 SDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMED 360 370 380 390 400 410 400 410 420 pF1KB6 EDEQGWCQGQLQSGRIGLYPANYVECVGA :::::::.:.:..:..::::::::: . XP_011 EDEQGWCKGRLDNGQVGLYPANYVEAIQ 420 430 440 >>XP_016884055 (OMIM: 604960) PREDICTED: protein kinase (447 aa) initn: 1610 init1: 1287 opt: 1418 Z-score: 887.4 bits: 173.3 E(85289): 1.1e-42 Smith-Waterman score: 1680; 55.9% identity (81.0% similar) in 442 aa overlap (4-422:6-446) 10 20 30 40 50 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLA ....: :. . ::::.:::.:::.:..::::::.::..:..:::::::::::::. XP_016 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DWARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAF .:::.:: :::::::::.:::: ::.. :::.: :::::. .:...: :... ::. :: XP_016 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 HRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADS :. ..:::.:.. :::::::::::: :.::::::.::..::: :.:: : .::...::: XP_016 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVSQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQR ... :::.:::...:.: ... ::: .::..: :: . ::.:::.:::.:: :: :..: XP_016 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 LLFFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQ : ::...:: ...:::::. .. ...::.:.:.::. :::::.:..::::::::::: XP_016 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 FE--EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPP-PQSPGSPGTGQD--EEW :: ::: : .::.::.:: .. : ::::.: : : . : :.: .: :. .: XP_016 FEDEEWSADLNRTLSRREKK-KATDGVTLTGINQTGDQSLPSKPSSVSSYEKTQSYPTDW 310 320 330 340 350 360 370 380 390 pF1KB6 SDEES--PRK--------------AATG--VRVRALYDYAGQEADELSFRAGEELLKMSE ::.:: : . :..: ::::::::: ::: :::::.::.:: :: . XP_016 SDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMED 360 370 380 390 400 410 400 410 420 pF1KB6 EDEQGWCQGQLQSGRIGLYPANYVECVGA :::::::.:.:..:..::::::::: . XP_016 EDEQGWCKGRLDNGQVGLYPANYVEAIQ 420 430 440 >>XP_016884056 (OMIM: 604960) PREDICTED: protein kinase (447 aa) initn: 1610 init1: 1287 opt: 1418 Z-score: 887.4 bits: 173.3 E(85289): 1.1e-42 Smith-Waterman score: 1680; 55.9% identity (81.0% similar) in 442 aa overlap (4-422:6-446) 10 20 30 40 50 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLA ....: :. . ::::.:::.:::.:..::::::.::..:..:::::::::::::. XP_016 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DWARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAF .:::.:: :::::::::.:::: ::.. :::.: :::::. .:...: :... ::. :: XP_016 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 HRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADS :. ..:::.:.. :::::::::::: :.::::::.::..::: :.:: : .::...::: XP_016 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVSQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQR ... :::.:::...:.: ... ::: .::..: :: . ::.:::.:::.:: :: :..: XP_016 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 LLFFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQ : ::...:: ...:::::. .. ...::.:.:.::. :::::.:..::::::::::: XP_016 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 FE--EWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPP-PQSPGSPGTGQD--EEW :: ::: : .::.::.:: .. : ::::.: : : . : :.: .: :. .: XP_016 FEDEEWSADLNRTLSRREKK-KATDGVTLTGINQTGDQSLPSKPSSVSSYEKTQSYPTDW 310 320 330 340 350 360 370 380 390 pF1KB6 SDEES--PRK--------------AATG--VRVRALYDYAGQEADELSFRAGEELLKMSE ::.:: : . :..: ::::::::: ::: :::::.::.:: :: . XP_016 SDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMED 360 370 380 390 400 410 400 410 420 pF1KB6 EDEQGWCQGQLQSGRIGLYPANYVECVGA :::::::.:.:..:..::::::::: . XP_016 EDEQGWCKGRLDNGQVGLYPANYVEAIQ 420 430 440 >>NP_009160 (OMIM: 604960) protein kinase C and casein k (486 aa) initn: 1690 init1: 1367 opt: 1407 Z-score: 880.2 bits: 172.1 E(85289): 2.7e-42 Smith-Waterman score: 1471; 50.7% identity (74.2% similar) in 454 aa overlap (4-395:6-458) 10 20 30 40 50 pF1KB6 MAPEEDAGGEALGGSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLA ....: :. . ::::.:::.:::.:..::::::.::..:..:::::::::::::. NP_009 MSVTYDDSVGVEVSSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DWARKWRGTVEKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAF .:::.:: :::::::::.:::: ::.. :::.: :::::. .:...: :... ::. :: NP_009 EWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 HRPVLGGFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADS :. ..:::.:.. :::::::::::: :.::::::.::..::: :.:: : .::...::: NP_009 HKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 AVSQEQLRKLQERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQR ... :::.:::...:.: ... ::: .::..: :: . ::.:::.:::.:: :: :..: NP_009 SLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 LLFFKDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQ : ::...:: ...:::::. .. ...::.:.:.::. :::::.:..::::::::::: NP_009 LRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQ 250 260 270 280 290 300 300 310 320 330 340 pF1KB6 FEEWSLDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAPP-PQS----PGSPGTG----- ::::: : .::.::.:: .. : ::::.: : : . : :.: :..:. . NP_009 FEEWSADLNRTLSRREKK-KATDGVTLTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQS 310 320 330 340 350 350 360 pF1KB6 -----QDEE-----------------------------WSDEES--PRK----------- .::. :::.:: : . NP_009 SYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPF 360 370 380 390 400 410 370 380 390 400 410 pF1KB6 ---AATG--VRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPA :..: ::::::::: ::: :::::.::.:: :: . NP_009 DDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPA 420 430 440 450 460 470 420 pF1KB6 NYVECVGA NP_009 NYVEAIQ 480 424 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:41:35 2016 done: Sat Nov 5 11:41:36 2016 Total Scan time: 7.640 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]