FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6667, 425 aa 1>>>pF1KB6667 425 - 425 aa - 425 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2107+/-0.000361; mu= 9.1737+/- 0.023 mean_var=126.7944+/-24.567, 0's: 0 Z-trim(117.3): 16 B-trim: 0 in 0/56 Lambda= 0.113900 statistics sampled from 29176 (29192) to 29176 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.342), width: 16 Scan time: 9.220 The best scores are: opt bits E(85289) NP_004171 (OMIM: 603893) TRAF family member-associ ( 425) 2860 481.1 2.3e-135 NP_001186064 (OMIM: 603893) TRAF family member-ass ( 425) 2860 481.1 2.3e-135 XP_016858585 (OMIM: 603893) PREDICTED: TRAF family ( 425) 2860 481.1 2.3e-135 XP_016858586 (OMIM: 603893) PREDICTED: TRAF family ( 425) 2860 481.1 2.3e-135 XP_016858584 (OMIM: 603893) PREDICTED: TRAF family ( 448) 2860 481.1 2.4e-135 XP_005246264 (OMIM: 603893) PREDICTED: TRAF family ( 451) 2860 481.1 2.4e-135 XP_016858583 (OMIM: 603893) PREDICTED: TRAF family ( 472) 2860 481.2 2.5e-135 XP_016858582 (OMIM: 603893) PREDICTED: TRAF family ( 483) 2860 481.2 2.5e-135 NP_597841 (OMIM: 603893) TRAF family member-associ ( 119) 706 126.8 2.8e-29 XP_005265449 (OMIM: 609916) PREDICTED: 5-azacytidi ( 392) 196 43.4 0.0013 NP_071906 (OMIM: 609916) 5-azacytidine-induced pro ( 392) 196 43.4 0.0013 XP_011532311 (OMIM: 609916) PREDICTED: 5-azacytidi ( 395) 196 43.4 0.0013 >>NP_004171 (OMIM: 603893) TRAF family member-associated (425 aa) initn: 2860 init1: 2860 opt: 2860 Z-score: 2551.4 bits: 481.1 E(85289): 2.3e-135 Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB6 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH 370 380 390 400 410 420 pF1KB6 FNGET ::::: NP_004 FNGET >>NP_001186064 (OMIM: 603893) TRAF family member-associa (425 aa) initn: 2860 init1: 2860 opt: 2860 Z-score: 2551.4 bits: 481.1 E(85289): 2.3e-135 Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB6 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH 370 380 390 400 410 420 pF1KB6 FNGET ::::: NP_001 FNGET >>XP_016858585 (OMIM: 603893) PREDICTED: TRAF family mem (425 aa) initn: 2860 init1: 2860 opt: 2860 Z-score: 2551.4 bits: 481.1 E(85289): 2.3e-135 Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB6 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH 370 380 390 400 410 420 pF1KB6 FNGET ::::: XP_016 FNGET >>XP_016858586 (OMIM: 603893) PREDICTED: TRAF family mem (425 aa) initn: 2860 init1: 2860 opt: 2860 Z-score: 2551.4 bits: 481.1 E(85289): 2.3e-135 Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB6 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH 370 380 390 400 410 420 pF1KB6 FNGET ::::: XP_016 FNGET >>XP_016858584 (OMIM: 603893) PREDICTED: TRAF family mem (448 aa) initn: 2860 init1: 2860 opt: 2860 Z-score: 2551.0 bits: 481.1 E(85289): 2.4e-135 Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:24-448) 10 20 30 pF1KB6 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENY ::::::::::::::::::::::::::::::::::::: XP_016 MKESGTRPVIYSILYSDATGRRGMDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 EQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 VISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAK 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 AQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 CRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNP 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 GNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNAL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 YVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCE 370 380 390 400 410 420 400 410 420 pF1KB6 FCQAVFPPSITSRGDFLRHLNSHFNGET :::::::::::::::::::::::::::: XP_016 FCQAVFPPSITSRGDFLRHLNSHFNGET 430 440 >>XP_005246264 (OMIM: 603893) PREDICTED: TRAF family mem (451 aa) initn: 2860 init1: 2860 opt: 2860 Z-score: 2551.0 bits: 481.1 E(85289): 2.4e-135 Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:27-451) 10 20 30 pF1KB6 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKT :::::::::::::::::::::::::::::::::: XP_005 MGVEGPAVSRPVIYSILYSDATGRRGMDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 ENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 QDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFHKICM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFHKICM 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 LAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSITSVTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSITSVTP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 RGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFNMEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFNMEFR 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 DNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDH 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 NALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPR 370 380 390 400 410 420 400 410 420 pF1KB6 VCEFCQAVFPPSITSRGDFLRHLNSHFNGET ::::::::::::::::::::::::::::::: XP_005 VCEFCQAVFPPSITSRGDFLRHLNSHFNGET 430 440 450 >>XP_016858583 (OMIM: 603893) PREDICTED: TRAF family mem (472 aa) initn: 2860 init1: 2860 opt: 2860 Z-score: 2550.7 bits: 481.2 E(85289): 2.5e-135 Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:48-472) 10 20 30 pF1KB6 MDKNIGEQLNKAYEAFRQACMDRDSAVKEL :::::::::::::::::::::::::::::: XP_016 THNFFFMDKEKCCRPVIYSILYSDATGRRGMDKNIGEQLNKAYEAFRQACMDRDSAVKEL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 QQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLT 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 LDQPQDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQPQDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFH 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB6 KICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSIT 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB6 SVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFN 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB6 MEFRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEFRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLP 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB6 PGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSEL 380 390 400 410 420 430 400 410 420 pF1KB6 HIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET ::::::::::::::::::::::::::::::::::: XP_016 HIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET 440 450 460 470 >>XP_016858582 (OMIM: 603893) PREDICTED: TRAF family mem (483 aa) initn: 2860 init1: 2860 opt: 2860 Z-score: 2550.5 bits: 481.2 E(85289): 2.5e-135 Smith-Waterman score: 2860; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:59-483) 10 20 30 pF1KB6 MDKNIGEQLNKAYEAFRQACMDRDSAVKEL :::::::::::::::::::::::::::::: XP_016 LPSYRGWNTHPNERPVIYSILYSDATGRRGMDKNIGEQLNKAYEAFRQACMDRDSAVKEL 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB6 QQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLT 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB6 LDQPQDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQPQDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFH 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB6 KICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSIT 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB6 SVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFN 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB6 MEFRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEFRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLP 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB6 PGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSEL 390 400 410 420 430 440 400 410 420 pF1KB6 HIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET ::::::::::::::::::::::::::::::::::: XP_016 HIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET 450 460 470 480 >>NP_597841 (OMIM: 603893) TRAF family member-associated (119 aa) initn: 706 init1: 706 opt: 706 Z-score: 646.6 bits: 126.8 E(85289): 2.8e-29 Smith-Waterman score: 706; 100.0% identity (100.0% similar) in 110 aa overlap (1-110:1-110) 10 20 30 40 50 60 pF1KB6 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_597 MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK :::::::::::::::::::::::::::::::::::::::::::::::::: NP_597 QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVDIASAESSI 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP >>XP_005265449 (OMIM: 609916) PREDICTED: 5-azacytidine-i (392 aa) initn: 144 init1: 118 opt: 196 Z-score: 186.0 bits: 43.4 E(85289): 0.0013 Smith-Waterman score: 196; 23.9% identity (63.3% similar) in 188 aa overlap (4-185:83-264) 10 20 30 pF1KB6 MDKNIG-EQLNKAYEAFRQACMDRDSAVKELQQ ..: ::.::::.:.:..:.:::. ..:.. XP_005 KDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDK 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB6 KTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLD ... . .. .:::. ... . .:.... ::. . : . :..: . : XP_005 MNKDNSESLKVLNEQLQSKEVELLQLRTEV----ETQQVMRNLNPPSSNWEVEKLSCDLK 120 130 140 150 160 100 110 120 130 140 pF1KB6 -QPQDKVISGIAREKLP-KVRRQEV--SSPRKETSARSLGSPLLH-ERGNIEKTFWDLKE . .. . . .: :.. :.. ..: .: . .: : :.....:.::. XP_005 IHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKR 170 180 190 200 210 220 150 160 170 180 190 200 pF1KB6 EFHKICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAP :. .. .....: . : ::. .:: . :. :. :.. XP_005 EMSNLHLVTQVQAELLRKLKT-STAIKKACA-PVGCSEDLGRDSTKLHLMNFTATYTRHP 230 240 250 260 270 280 210 220 230 240 250 260 pF1KB6 SITSVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQE XP_005 PLLPNGKALCHTTSSPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLED 290 300 310 320 330 340 425 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:07:52 2016 done: Sat Nov 5 20:07:54 2016 Total Scan time: 9.220 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]