FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6668, 453 aa 1>>>pF1KB6668 453 - 453 aa - 453 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7285+/-0.000832; mu= 16.8388+/- 0.051 mean_var=88.2570+/-17.662, 0's: 0 Z-trim(109.6): 8 B-trim: 155 in 1/51 Lambda= 0.136521 statistics sampled from 11009 (11014) to 11009 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.338), width: 16 Scan time: 3.360 The best scores are: opt bits E(32554) CCDS977.1 PRUNE1 gene_id:58497|Hs108|chr1 ( 453) 2949 590.7 1e-168 CCDS76211.1 PRUNE1 gene_id:58497|Hs108|chr1 ( 271) 1764 357.1 1.3e-98 CCDS78407.1 PRUNE2 gene_id:158471|Hs108|chr9 (3062) 441 97.3 2.3e-19 CCDS47982.1 PRUNE2 gene_id:158471|Hs108|chr9 (3088) 441 97.3 2.4e-19 >>CCDS977.1 PRUNE1 gene_id:58497|Hs108|chr1 (453 aa) initn: 2949 init1: 2949 opt: 2949 Z-score: 3142.3 bits: 590.7 E(32554): 1e-168 Smith-Waterman score: 2949; 100.0% identity (100.0% similar) in 453 aa overlap (1-453:1-453) 10 20 30 40 50 60 pF1KB6 MEDYLQGCRAALQESRPLHVVLGNEACDLDSTVSALALAFYLAKTTEAEEVFVPVLNIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MEDYLQGCRAALQESRPLHVVLGNEACDLDSTVSALALAFYLAKTTEAEEVFVPVLNIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQLTLILVDHHILSKSDTALEEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 SELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQLTLILVDHHILSKSDTALEEA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VAEVLDHRPIEPKHCPPCHVSVELVGSCATLVTERILQGAPEILDRQTAALLHGTIILDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 VAEVLDHRPIEPKHCPPCHVSVELVGSCATLVTERILQGAPEILDRQTAALLHGTIILDC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VNMDLKIGKATPKDSKYVEKLEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKDQKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 VNMDLKIGKATPKDSKYVEKLEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKDQKT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IYRQGVKVAISAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 IYRQGVKVAISAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKKLLPLLQEALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 IFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKKLLPLLQEALS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 AYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQDEEDPPLPPTPMNSLVDECP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 AYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQDEEDPPLPPTPMNSLVDECP 370 380 390 400 410 420 430 440 450 pF1KB6 LDQGLPKLSAEAVFEKCSQISLSQSTTASLSKK ::::::::::::::::::::::::::::::::: CCDS97 LDQGLPKLSAEAVFEKCSQISLSQSTTASLSKK 430 440 450 >>CCDS76211.1 PRUNE1 gene_id:58497|Hs108|chr1 (271 aa) initn: 1764 init1: 1764 opt: 1764 Z-score: 1884.1 bits: 357.1 E(32554): 1.3e-98 Smith-Waterman score: 1764; 100.0% identity (100.0% similar) in 271 aa overlap (183-453:1-271) 160 170 180 190 200 210 pF1KB6 TERILQGAPEILDRQTAALLHGTIILDCVNMDLKIGKATPKDSKYVEKLEALFPDLPKRN :::::::::::::::::::::::::::::: CCDS76 MDLKIGKATPKDSKYVEKLEALFPDLPKRN 10 20 30 220 230 240 250 260 270 pF1KB6 DIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQGVKVAISAIYMDLEAFLQRSNLLADLHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 DIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQGVKVAISAIYMDLEAFLQRSNLLADLHA 40 50 60 70 80 90 280 290 300 310 320 330 pF1KB6 FCQAHSYDVLVAMTIFFNTHNEPVRQLAIFCPHVALQTTICEVLERSHSPPLKLTPASST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 FCQAHSYDVLVAMTIFFNTHNEPVRQLAIFCPHVALQTTICEVLERSHSPPLKLTPASST 100 110 120 130 140 150 340 350 360 370 380 390 pF1KB6 HPNLHAYLQGNTQVSRKKLLPLLQEALSAYFDSMKIPSGQPETADVSREQVDKELDRASN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 HPNLHAYLQGNTQVSRKKLLPLLQEALSAYFDSMKIPSGQPETADVSREQVDKELDRASN 160 170 180 190 200 210 400 410 420 430 440 450 pF1KB6 SLISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 SLISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASLSK 220 230 240 250 260 270 pF1KB6 K : CCDS76 K >>CCDS78407.1 PRUNE2 gene_id:158471|Hs108|chr9 (3062 aa) initn: 718 init1: 325 opt: 441 Z-score: 461.0 bits: 97.3 E(32554): 2.3e-19 Smith-Waterman score: 734; 33.3% identity (66.5% similar) in 409 aa overlap (1-406:1-397) 10 20 30 40 50 pF1KB6 MEDYLQGCRAALQESRPL---HVVLGNEACDLDSTVSALALAFYLAKTTEAEEVFVPVLN ::..:: .. :..:. : :::.: ..::::: .:... :..: :.. . .:::: CCDS78 MEEFLQRAKSKLNRSKRLEKVHVVIGPKSCDLDSLISTFTYAYFLDKVSPPGVLCLPVLN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 IKRSELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQLTLILVDHHILSKSDTAL : :.:. . :.:....: ::. ::::::.:: : . :.:.. :: .:.. : .: CCDS78 IPRTEFNYFTETRFILEELNISESFHIFRDEINLHQLNDEGKLSITLVGSSVLASEDKTL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 EEAVAEVLDHRPIEPKHCPPCHVSVELVGSCATLVTERILQGAPEILDRQTAALLHGTII : ::..:.. :.: . ..::. : ..:: ..::: :::.. .: : :.:.:. CCDS78 ESAVVKVIN--PVEQSD-----ANVEFRESSSSLVLKEILQEAPELITEQLAHRLRGSIL 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 LDCVNMDLKIGKATPKDSKYVEKLEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKD . ..:. . : . :. . . :: ::.:: :.::.. ::...:...::. :: . :: CCDS78 FKWMTMESE--KISEKQEEILSILEEKFPNLPPREDIINVLQETQFSAQGLSIEQTMLKD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 QKTIYRQGVKVAISAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVR : . .:::::.. :.:: : .::. .::.:: . ..:::. .. ... ...: : CCDS78 LKELSDGEIKVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFSSYLSEEQQPRR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 QLAIFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKKLLPLLQE :.:.. .. : . :: ::. ..: :.: : . .. .: : . .:. ... ...: CCDS78 QIAVYSENMELCSQICCELEECQNPCLELEPFDCGCDEILVYQQEDPSVTCDQVVLVVKE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 ALSAYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQDEEDPPLPPTPMNSLVD ... : : : :. . :...:.... ..: : : CCDS78 VINRRCPEMVSNSRTSSTEAVAG---SAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPD 360 370 380 390 400 420 430 440 450 pF1KB6 ECPLDQGLPKLSAEAVFEKCSQISLSQSTTASLSKK CCDS78 LNDSNQAQVDANVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDS 410 420 430 440 450 460 >>CCDS47982.1 PRUNE2 gene_id:158471|Hs108|chr9 (3088 aa) initn: 718 init1: 325 opt: 441 Z-score: 461.0 bits: 97.3 E(32554): 2.4e-19 Smith-Waterman score: 734; 33.3% identity (66.5% similar) in 409 aa overlap (1-406:1-397) 10 20 30 40 50 pF1KB6 MEDYLQGCRAALQESRPL---HVVLGNEACDLDSTVSALALAFYLAKTTEAEEVFVPVLN ::..:: .. :..:. : :::.: ..::::: .:... :..: :.. . .:::: CCDS47 MEEFLQRAKSKLNRSKRLEKVHVVIGPKSCDLDSLISTFTYAYFLDKVSPPGVLCLPVLN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 IKRSELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQLTLILVDHHILSKSDTAL : :.:. . :.:....: ::. ::::::.:: : . :.:.. :: .:.. : .: CCDS47 IPRTEFNYFTETRFILEELNISESFHIFRDEINLHQLNDEGKLSITLVGSSVLASEDKTL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 EEAVAEVLDHRPIEPKHCPPCHVSVELVGSCATLVTERILQGAPEILDRQTAALLHGTII : ::..:.. :.: . ..::. : ..:: ..::: :::.. .: : :.:.:. CCDS47 ESAVVKVIN--PVEQSD-----ANVEFRESSSSLVLKEILQEAPELITEQLAHRLRGSIL 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 LDCVNMDLKIGKATPKDSKYVEKLEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKD . ..:. . : . :. . . :: ::.:: :.::.. ::...:...::. :: . :: CCDS47 FKWMTMESE--KISEKQEEILSILEEKFPNLPPREDIINVLQETQFSAQGLSIEQTMLKD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 QKTIYRQGVKVAISAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVR : . .:::::.. :.:: : .::. .::.:: . ..:::. .. ... ...: : CCDS47 LKELSDGEIKVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFSSYLSEEQQPRR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 QLAIFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKKLLPLLQE :.:.. .. : . :: ::. ..: :.: : . .. .: : . .:. ... ...: CCDS47 QIAVYSENMELCSQICCELEECQNPCLELEPFDCGCDEILVYQQEDPSVTCDQVVLVVKE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 ALSAYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQDEEDPPLPPTPMNSLVD ... : : : :. . :...:.... ..: : : CCDS47 VINRRCPEMVSNSRTSSTEAVAG---SAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPD 360 370 380 390 400 420 430 440 450 pF1KB6 ECPLDQGLPKLSAEAVFEKCSQISLSQSTTASLSKK CCDS47 LNDSNQAQVDANVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDS 410 420 430 440 450 460 453 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:42:13 2016 done: Sat Nov 5 11:42:14 2016 Total Scan time: 3.360 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]