FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6669, 425 aa 1>>>pF1KB6669 425 - 425 aa - 425 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9240+/-0.000405; mu= 14.4099+/- 0.025 mean_var=83.2272+/-16.766, 0's: 0 Z-trim(112.4): 24 B-trim: 965 in 1/48 Lambda= 0.140586 statistics sampled from 21247 (21270) to 21247 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.249), width: 16 Scan time: 9.010 The best scores are: opt bits E(85289) NP_060296 (OMIM: 616066) spermatogenesis- and ooge ( 425) 2779 573.7 3e-163 NP_001269076 (OMIM: 616066) spermatogenesis- and o ( 225) 1374 288.6 1.1e-77 XP_005263460 (OMIM: 610224) PREDICTED: spermatogen ( 409) 159 42.3 0.0027 XP_011517000 (OMIM: 610224) PREDICTED: spermatogen ( 409) 159 42.3 0.0027 NP_001012415 (OMIM: 610224) spermatogenesis- and o ( 328) 157 41.9 0.0029 NP_001095147 (OMIM: 610224) spermatogenesis- and o ( 387) 157 41.9 0.0034 XP_005260242 (OMIM: 604745) PREDICTED: transcripti ( 499) 153 41.2 0.0073 NP_006593 (OMIM: 604745) transcription factor-like ( 500) 153 41.2 0.0073 >>NP_060296 (OMIM: 616066) spermatogenesis- and oogenesi (425 aa) initn: 2779 init1: 2779 opt: 2779 Z-score: 3051.9 bits: 573.7 E(85289): 3e-163 Smith-Waterman score: 2779; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB6 MASSIICQEHCQISGQAKIDILLVGDVTVGYLADTVQKLFANIAEVTITISDTKEAAALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MASSIICQEHCQISGQAKIDILLVGDVTVGYLADTVQKLFANIAEVTITISDTKEAAALL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DDCIFNMVLLKVPSSLSAEELEAIKLIRFGKKKNTHSLFVFIIPENFKGCISGHGMDIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DDCIFNMVLLKVPSSLSAEELEAIKLIRFGKKKNTHSLFVFIIPENFKGCISGHGMDIAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TEPLTMEKMSNVVKYWTTCPSNTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TEPLTMEKMSNVVKYWTTCPSNTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LRNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LRNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 VLEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VLEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TYSPERGLQFLTNTCWNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISSAALSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TYSPERGLQFLTNTCWNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISSAALSLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 SLHTVRYYSKVTPSYDATAVTNQNISIHLPSAMPPVSKLLPRHCTSGLGQTCTTHPNCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SLHTVRYYSKVTPSYDATAVTNQNISIHLPSAMPPVSKLLPRHCTSGLGQTCTTHPNCLQ 370 380 390 400 410 420 pF1KB6 QFWAY ::::: NP_060 QFWAY >>NP_001269076 (OMIM: 616066) spermatogenesis- and oogen (225 aa) initn: 1374 init1: 1374 opt: 1374 Z-score: 1516.0 bits: 288.6 E(85289): 1.1e-77 Smith-Waterman score: 1374; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214) 10 20 30 40 50 60 pF1KB6 MASSIICQEHCQISGQAKIDILLVGDVTVGYLADTVQKLFANIAEVTITISDTKEAAALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASSIICQEHCQISGQAKIDILLVGDVTVGYLADTVQKLFANIAEVTITISDTKEAAALL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DDCIFNMVLLKVPSSLSAEELEAIKLIRFGKKKNTHSLFVFIIPENFKGCISGHGMDIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDCIFNMVLLKVPSSLSAEELEAIKLIRFGKKKNTHSLFVFIIPENFKGCISGHGMDIAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TEPLTMEKMSNVVKYWTTCPSNTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEPLTMEKMSNVVKYWTTCPSNTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LRNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAAS :::::::::::::::::::::::::::::::::: NP_001 LRNGNGLELNASLSEFEKNKKISLLHSSKEKLRRLYRKHSSFCFW 190 200 210 220 250 260 270 280 290 300 pF1KB6 VLEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMS >>XP_005263460 (OMIM: 610224) PREDICTED: spermatogenesis (409 aa) initn: 175 init1: 142 opt: 159 Z-score: 180.3 bits: 42.3 E(85289): 0.0027 Smith-Waterman score: 166; 25.9% identity (54.4% similar) in 193 aa overlap (152-344:10-180) 130 140 150 160 170 180 pF1KB6 EPLTMEKMSNVVKYWTTCPSNTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSESL :: .: :. . : . : : .: XP_005 MASRCSEPYPEVSRIPTVRGCN---GSLSGALSCCEDSA 10 20 30 190 200 210 220 230 240 pF1KB6 RNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAASV : :.: ...: .. . : .: ::.:.. ::.::.::: ::..: ::: XP_005 R-GSGPPKAPTVAEGPSSCLRRNVISERE--RRKRMSLSCERLRALLPQFDGRREDMASV 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB6 LEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMST :: .:.... . ..:. . : ...: . . :. ..:.: . ..: .. XP_005 LEMSVQFLR-LASALGPSQEQHAILASSKEM-WHSLQEDVLQLTLSSQIQA-------GV 100 110 120 130 140 310 320 330 340 350 360 pF1KB6 YSPERGLQFLTNTCWNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISSAALSLNS .: : . .: :::... :. . .::: . . XP_005 PDPGTGAS-------SGTRTPDVKAFLESPWSLDPASASPEPVPHILASSRQWDPASCTS 150 160 170 180 190 370 380 390 400 410 420 pF1KB6 LHTVRYYSKVTPSYDATAVTNQNISIHLPSAMPPVSKLLPRHCTSGLGQTCTTHPNCLQQ XP_005 LGTDKCEALLGLCQVRGGLPPFSEPSSLVPWPPGRSLPKAVRPPLSWPPFSQQQTLPVMS 200 210 220 230 240 250 >>XP_011517000 (OMIM: 610224) PREDICTED: spermatogenesis (409 aa) initn: 175 init1: 142 opt: 159 Z-score: 180.3 bits: 42.3 E(85289): 0.0027 Smith-Waterman score: 166; 25.9% identity (54.4% similar) in 193 aa overlap (152-344:10-180) 130 140 150 160 170 180 pF1KB6 EPLTMEKMSNVVKYWTTCPSNTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSESL :: .: :. . : . : : .: XP_011 MASRCSEPYPEVSRIPTVRGCN---GSLSGALSCCEDSA 10 20 30 190 200 210 220 230 240 pF1KB6 RNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAASV : :.: ...: .. . : .: ::.:.. ::.::.::: ::..: ::: XP_011 R-GSGPPKAPTVAEGPSSCLRRNVISERE--RRKRMSLSCERLRALLPQFDGRREDMASV 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB6 LEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMST :: .:.... . ..:. . : ...: . . :. ..:.: . ..: .. XP_011 LEMSVQFLR-LASALGPSQEQHAILASSKEM-WHSLQEDVLQLTLSSQIQA-------GV 100 110 120 130 140 310 320 330 340 350 360 pF1KB6 YSPERGLQFLTNTCWNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISSAALSLNS .: : . .: :::... :. . .::: . . XP_011 PDPGTGAS-------SGTRTPDVKAFLESPWSLDPASASPEPVPHILASSRQWDPASCTS 150 160 170 180 190 370 380 390 400 410 420 pF1KB6 LHTVRYYSKVTPSYDATAVTNQNISIHLPSAMPPVSKLLPRHCTSGLGQTCTTHPNCLQQ XP_011 LGTDKCEALLGLCQVRGGLPPFSEPSSLVPWPPGRSLPKAVRPPLSWPPFSQQQTLPVMS 200 210 220 230 240 250 >>NP_001012415 (OMIM: 610224) spermatogenesis- and oogen (328 aa) initn: 196 init1: 142 opt: 157 Z-score: 179.5 bits: 41.9 E(85289): 0.0029 Smith-Waterman score: 164; 24.9% identity (54.9% similar) in 193 aa overlap (152-344:10-180) 130 140 150 160 170 180 pF1KB6 EPLTMEKMSNVVKYWTTCPSNTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSESL :: .: :. . : . ..: :. NP_001 MASRCSEPYPEVSRIPTVRGCNGSL----SGALSCCEDS 10 20 30 190 200 210 220 230 240 pF1KB6 RNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAASV .:.: ...: .. . : .: ::.:.. ::.::.::: ::..: ::: NP_001 AQGSGPPKAPTVAEGPSSCLRRNVISERE--RRKRMSLSCERLRALLPQFDGRREDMASV 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB6 LEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMST :: .:.... . ..:. . : ...: . . :. ..:.: . ..: .. NP_001 LEMSVQFLR-LASALGPSQEQHAILASSKEM-WHSLQEDVLQLTLSSQIQA-------GV 100 110 120 130 140 310 320 330 340 350 360 pF1KB6 YSPERGLQFLTNTCWNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISSAALSLNS .: : . .: :::... :. . .::: . . NP_001 PDPGTGAS-------SGTRTPDVKAFLESPWSLDPASASPEPVPHILASSRQWDPASCTS 150 160 170 180 190 370 380 390 400 410 420 pF1KB6 LHTVRYYSKVTPSYDATAVTNQNISIHLPSAMPPVSKLLPRHCTSGLGQTCTTHPNCLQQ NP_001 LGTDKCEALLGLCQVRGGLPPFSEPSSLVPWPPGRSLPKAVRPPLSWPPFSQQQTLPVMS 200 210 220 230 240 250 >>NP_001095147 (OMIM: 610224) spermatogenesis- and oogen (387 aa) initn: 175 init1: 142 opt: 157 Z-score: 178.4 bits: 41.9 E(85289): 0.0034 Smith-Waterman score: 164; 24.9% identity (54.9% similar) in 193 aa overlap (152-344:10-180) 130 140 150 160 170 180 pF1KB6 EPLTMEKMSNVVKYWTTCPSNTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSESL :: .: :. . : . ..: :. NP_001 MASRCSEPYPEVSRIPTVRGCNGSL----SGALSCCEDS 10 20 30 190 200 210 220 230 240 pF1KB6 RNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAASV .:.: ...: .. . : .: ::.:.. ::.::.::: ::..: ::: NP_001 AQGSGPPKAPTVAEGPSSCLRRNVISERE--RRKRMSLSCERLRALLPQFDGRREDMASV 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB6 LEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMST :: .:.... . ..:. . : ...: . . :. ..:.: . ..: .. NP_001 LEMSVQFLR-LASALGPSQEQHAILASSKEM-WHSLQEDVLQLTLSSQIQA-------GV 100 110 120 130 140 310 320 330 340 350 360 pF1KB6 YSPERGLQFLTNTCWNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISSAALSLNS .: : . .: :::... :. . .::: . . NP_001 PDPGTGAS-------SGTRTPDVKAFLESPWSLDPASASPEPVPHILASSRQWDPASCTS 150 160 170 180 190 370 380 390 400 410 420 pF1KB6 LHTVRYYSKVTPSYDATAVTNQNISIHLPSAMPPVSKLLPRHCTSGLGQTCTTHPNCLQQ NP_001 LGTDKCEALLGLCQVRGGLPPFSEPSSLVPWPPGRSLPKAVRPPLSWPPFSQQQTLPVMS 200 210 220 230 240 250 >>XP_005260242 (OMIM: 604745) PREDICTED: transcription f (499 aa) initn: 116 init1: 88 opt: 153 Z-score: 172.4 bits: 41.2 E(85289): 0.0073 Smith-Waterman score: 153; 28.7% identity (63.4% similar) in 101 aa overlap (206-305:404-497) 180 190 200 210 220 230 pF1KB6 ACSESLRNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRK :. :. ::.::. ::..: :.:. .. . XP_005 AWQSSESSQANLGEQAQSGPQGGRSQRRERHNRMERDRRRRIRICCDELNLLVPFCNA-E 380 390 400 410 420 430 240 250 260 270 280 290 pF1KB6 NDAASVLEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGT-VMAQR .: :..:. :. ..:::.:. . .. .. . :: : ..:. : . : XP_005 TDKATTLQWTTAFLKYIQERHGDSLKKEFESV------FCGKTGRRLKLTRPDSLVTCPA 440 450 460 470 480 300 310 320 330 340 350 pF1KB6 ENSVMSTYSPERGLQFLTNTCWNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISS ..:..:. : : XP_005 QGSLQSSPSMEIK 490 >>NP_006593 (OMIM: 604745) transcription factor-like 5 p (500 aa) initn: 116 init1: 88 opt: 153 Z-score: 172.4 bits: 41.2 E(85289): 0.0073 Smith-Waterman score: 153; 28.7% identity (63.4% similar) in 101 aa overlap (206-305:405-498) 180 190 200 210 220 230 pF1KB6 ACSESLRNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRK :. :. ::.::. ::..: :.:. .. . NP_006 AWQSSESSQANLGEQAQSGPQGGRSQRRERHNRMERDRRRRIRICCDELNLLVPFCNA-E 380 390 400 410 420 430 240 250 260 270 280 290 pF1KB6 NDAASVLEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGT-VMAQR .: :..:. :. ..:::.:. . .. .. . :: : ..:. : . : NP_006 TDKATTLQWTTAFLKYIQERHGDSLKKEFESV------FCGKTGRRLKLTRPDSLVTCPA 440 450 460 470 480 300 310 320 330 340 350 pF1KB6 ENSVMSTYSPERGLQFLTNTCWNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISS ..:..:. : : NP_006 QGSLQSSPSMEIK 490 500 425 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:19:04 2016 done: Sat Nov 5 11:19:05 2016 Total Scan time: 9.010 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]