FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6671, 426 aa 1>>>pF1KB6671 426 - 426 aa - 426 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8314+/-0.000361; mu= 14.2337+/- 0.023 mean_var=66.8289+/-13.697, 0's: 0 Z-trim(113.0): 54 B-trim: 0 in 0/54 Lambda= 0.156889 statistics sampled from 22056 (22110) to 22056 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.259), width: 16 Scan time: 7.850 The best scores are: opt bits E(85289) NP_057272 (OMIM: 612458) actin-like protein 6B [Ho ( 426) 2893 663.8 2.2e-190 NP_004292 (OMIM: 604958) actin-like protein 6A iso ( 429) 2505 576.0 6.2e-164 NP_817126 (OMIM: 604958) actin-like protein 6A iso ( 387) 2236 515.1 1.2e-145 NP_829888 (OMIM: 604958) actin-like protein 6A iso ( 387) 2236 515.1 1.2e-145 NP_001091 (OMIM: 102610,161800,255310,616852) acti ( 377) 460 113.1 1.2e-24 NP_005150 (OMIM: 102540,612098,612794,613424) acti ( 377) 454 111.8 3.1e-24 NP_001092 (OMIM: 102630,243310,607371,608578) acti ( 375) 452 111.3 4.2e-24 NP_001186883 (OMIM: 102560,604717,614583) actin, c ( 375) 451 111.1 4.9e-24 NP_001605 (OMIM: 102560,604717,614583) actin, cyto ( 375) 451 111.1 4.9e-24 NP_001606 (OMIM: 102545) actin, gamma-enteric smoo ( 376) 445 109.7 1.3e-23 NP_001604 (OMIM: 102620,611788,613834,614042) acti ( 377) 439 108.4 3.2e-23 NP_001307784 (OMIM: 102620,611788,613834,614042) a ( 377) 439 108.4 3.2e-23 NP_001135417 (OMIM: 102620,611788,613834,614042) a ( 377) 439 108.4 3.2e-23 NP_001017992 (OMIM: 614835) beta-actin-like protei ( 376) 431 106.6 1.1e-22 NP_005726 (OMIM: 605144) beta-centractin [Homo sap ( 376) 416 103.2 1.2e-21 NP_005727 (OMIM: 605143) alpha-centractin [Homo sa ( 376) 410 101.8 3e-21 XP_016859649 (OMIM: 608914) PREDICTED: POTE ankyri ( 657) 413 102.6 3.2e-21 XP_011509518 (OMIM: 608914) PREDICTED: POTE ankyri ( 957) 413 102.6 4.5e-21 XP_016859648 (OMIM: 608914) PREDICTED: POTE ankyri ( 967) 413 102.6 4.5e-21 XP_016859650 (OMIM: 608914) PREDICTED: POTE ankyri (1075) 413 102.6 5e-21 NP_001077007 (OMIM: 608914) POTE ankyrin domain fa (1075) 413 102.6 5e-21 NP_005712 (OMIM: 604222) actin-related protein 3 i ( 418) 403 100.3 1e-20 NP_001264069 (OMIM: 604222) actin-related protein ( 367) 364 91.4 4.1e-18 XP_016858605 (OMIM: 605144) PREDICTED: beta-centra ( 332) 351 88.5 2.8e-17 NP_006677 (OMIM: 604304) actin-like protein 7B [Ho ( 415) 349 88.0 4.8e-17 NP_536356 (OMIM: 608535) actin-related protein T2 ( 377) 345 87.1 8.2e-17 XP_005263911 (OMIM: 605144) PREDICTED: beta-centra ( 302) 341 86.2 1.3e-16 NP_001186822 (OMIM: 102545) actin, gamma-enteric s ( 333) 320 81.4 3.7e-15 NP_115876 (OMIM: 608534) actin-related protein T3 ( 372) 313 79.9 1.2e-14 NP_001005386 (OMIM: 604221) actin-related protein ( 399) 310 79.2 2.1e-14 NP_006678 (OMIM: 604303) actin-like protein 7A [Ho ( 435) 308 78.8 3.1e-14 NP_612146 (OMIM: 300487) actin-related protein T1 ( 376) 301 77.2 8.1e-14 NP_005713 (OMIM: 604221) actin-related protein 2 i ( 394) 295 75.8 2.2e-13 >>NP_057272 (OMIM: 612458) actin-like protein 6B [Homo s (426 aa) initn: 2893 init1: 2893 opt: 2893 Z-score: 3538.8 bits: 663.8 E(85289): 2.2e-190 Smith-Waterman score: 2893; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426) 10 20 30 40 50 60 pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC 370 380 390 400 410 420 pF1KB6 VERKCP :::::: NP_057 VERKCP >>NP_004292 (OMIM: 604958) actin-like protein 6A isoform (429 aa) initn: 2493 init1: 2209 opt: 2505 Z-score: 3064.1 bits: 576.0 E(85289): 6.2e-164 Smith-Waterman score: 2505; 83.9% identity (95.6% similar) in 429 aa overlap (1-426:1-429) 10 20 30 40 50 pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGG--LELEGDK ::::::::::::::::::::..::::::::::::.::::..:... .. :. .:..::: NP_004 MSGGVYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 EKKG-KIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPV :.: ..::::::.:::.. :..:::::::.:::. :.:::::::. ::::: .:::: NP_004 GKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 LMSEAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAI ::::::::::::::::::::::.:::::::::::::::::::::::::.::::::::::: NP_004 LMSEAPWNTRAKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 PVHDGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKK ::::::::::::::::::::::.:::::::::: :...::::::.:: ::::.: :::.: NP_004 PVHDGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 EKLPQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAE ::::::..:::::::: ::::::::::::::: :::::::::::::::.::::: :.::: NP_004 EKLPQVTRSWHNYMCNCVIQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 RLRIPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGF ::.::::::::::::::::::::::.::::::.:::::::::::::::::.:::::.:.: NP_004 RLKIPEGLFDPSNVKGLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB6 TDRLNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGG ::::::::::::::::::::::.:.:.::.:: ::::::::::::::::::::::::::: NP_004 TDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGG 370 380 390 400 410 420 420 pF1KB6 KQCVERKCP ::::::::: NP_004 KQCVERKCP >>NP_817126 (OMIM: 604958) actin-like protein 6A isoform (387 aa) initn: 2209 init1: 2209 opt: 2236 Z-score: 2735.8 bits: 515.1 E(85289): 1.2e-145 Smith-Waterman score: 2236; 85.6% identity (96.0% similar) in 376 aa overlap (52-426:12-387) 30 40 50 60 70 80 pF1KB6 SVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEKKG-KIFHIDTNALHVPRDGAE .:..::: :.: ..::::::.:::.. : NP_817 MVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENME 10 20 30 40 90 100 110 120 130 140 pF1KB6 VMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMSEAPWNTRAKREKLTELMFEQ ..:::::::.:::. :.:::::::. ::::: .::::::::::::::::::::::::::. NP_817 AISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFEH 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB6 YNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFIS :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::. NP_817 YNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFIT 110 120 130 140 150 160 210 220 230 240 250 260 pF1KB6 MQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKLPQVSKSWHNYMCNEVIQDFQ :::::::::: :...::::::.:: ::::.: :::.:::::::..:::::::: :::::: NP_817 MQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQ 170 180 190 200 210 220 270 280 290 300 310 320 pF1KB6 ASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGLFDPSNVKGLSGNTML ::::::::: :::::::::::::::.::::: :.:::::.:::::::::::::::::::: NP_817 ASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTML 230 240 250 260 270 280 330 340 350 360 370 380 pF1KB6 GVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIAS ::.::::::.:::::::::::::::::.:::::.:.:::::::::::::::::::::::. NP_817 GVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIAN 290 300 310 320 330 340 390 400 410 420 pF1KB6 NSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP :.:.::.:: :::::::::::::::::::::::::::::::::::: NP_817 NTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP 350 360 370 380 >>NP_829888 (OMIM: 604958) actin-like protein 6A isoform (387 aa) initn: 2209 init1: 2209 opt: 2236 Z-score: 2735.8 bits: 515.1 E(85289): 1.2e-145 Smith-Waterman score: 2236; 85.6% identity (96.0% similar) in 376 aa overlap (52-426:12-387) 30 40 50 60 70 80 pF1KB6 SVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEKKG-KIFHIDTNALHVPRDGAE .:..::: :.: ..::::::.:::.. : NP_829 MVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENME 10 20 30 40 90 100 110 120 130 140 pF1KB6 VMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMSEAPWNTRAKREKLTELMFEQ ..:::::::.:::. :.:::::::. ::::: .::::::::::::::::::::::::::. NP_829 AISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFEH 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB6 YNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFIS :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::. NP_829 YNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFIT 110 120 130 140 150 160 210 220 230 240 250 260 pF1KB6 MQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKLPQVSKSWHNYMCNEVIQDFQ :::::::::: :...::::::.:: ::::.: :::.:::::::..:::::::: :::::: NP_829 MQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQ 170 180 190 200 210 220 270 280 290 300 310 320 pF1KB6 ASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGLFDPSNVKGLSGNTML ::::::::: :::::::::::::::.::::: :.:::::.:::::::::::::::::::: NP_829 ASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTML 230 240 250 260 270 280 330 340 350 360 370 380 pF1KB6 GVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIAS ::.::::::.:::::::::::::::::.:::::.:.:::::::::::::::::::::::. NP_829 GVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIAN 290 300 310 320 330 340 390 400 410 420 pF1KB6 NSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP :.:.::.:: :::::::::::::::::::::::::::::::::::: NP_829 NTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP 350 360 370 380 >>NP_001091 (OMIM: 102610,161800,255310,616852) actin, a (377 aa) initn: 881 init1: 319 opt: 460 Z-score: 563.5 bits: 113.1 E(85289): 1.2e-24 Smith-Waterman score: 872; 37.6% identity (64.3% similar) in 417 aa overlap (9-425:5-376) 10 20 30 40 50 60 pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK ::. ::: : :: :.::.::.: :.: ::. :: .. : . :.:.. NP_001 MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS .. .: . : . :...:.: .:. .. : ::. .... :. ::.:.. NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLT 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH ::: : .:.:::.:..::: .:.::... :::. .:.::.::.::::: : .:.. NP_001 EAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIY 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL .::.: ..:.. ::: .. ... : . ... : .: ::. :::: NP_001 EGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVT---TAEREIVRD-------IKEKL 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR : : ::. . ...: :. ::.:.: : ::.: NP_001 -----------CY-VALDFENEMATAASSSSLEK--------SYELPDGQVITIGNERFR 220 230 240 250 310 320 330 340 350 360 pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR :: ::.:: . : :. ... .:: :::::: ::.. ...::.:. :..:: NP_001 CPETLFQPSFI----GMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADR 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC ...:.. .: .:..:.:: :::.: ::::::::::.:::::::.::::.:.: . NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSI 320 330 340 350 360 370 pF1KB6 VERKCP :.::: NP_001 VHRKCF >>NP_005150 (OMIM: 102540,612098,612794,613424) actin, a (377 aa) initn: 878 init1: 319 opt: 454 Z-score: 556.2 bits: 111.8 E(85289): 3.1e-24 Smith-Waterman score: 869; 37.6% identity (64.3% similar) in 417 aa overlap (9-425:5-376) 10 20 30 40 50 60 pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK .:. ::: : :: :.::.::.: :.: ::. :: .. : . :.:.. NP_005 MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS .. .: . : . :...:.: .:. .. : ::. .... :. ::.:.. NP_005 -----YVGDEA-QSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLT 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH ::: : .:.:::.:..::: .:.::... :::. .:.::.::.::::: : .:.. NP_005 EAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIY 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL .::.: ..:.. ::: .. ... : . ... : .: ::. :::: NP_005 EGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVT---TAEREIVRD-------IKEKL 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR : : ::. . ...: :. ::.:.: : ::.: NP_005 -----------CY-VALDFENEMATAASSSSLEK--------SYELPDGQVITIGNERFR 220 230 240 250 310 320 330 340 350 360 pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR :: ::.:: . : :. ... .:: :::::: ::.. ...::.:. :..:: NP_005 CPETLFQPSFI----GMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADR 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC ...:.. .: .:..:.:: :::.: ::::::::::.::::::::::::.:.: . NP_005 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSI 320 330 340 350 360 370 pF1KB6 VERKCP :.::: NP_005 VHRKCF >>NP_001092 (OMIM: 102630,243310,607371,608578) actin, c (375 aa) initn: 885 init1: 318 opt: 452 Z-score: 553.7 bits: 111.3 E(85289): 4.2e-24 Smith-Waterman score: 868; 36.9% identity (64.5% similar) in 417 aa overlap (9-425:3-374) 10 20 30 40 50 60 pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK :...::: : :: .::.::.: :.: ::. :: .. : . :.:.. NP_001 MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS .. .: . : . :...:.. .:. .. : ::. .... :. ::::.. NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLT 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH ::: : .:.:::.:..::: .: ::... :::. .:.::.::.:.::: : ..:.. NP_001 EAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIY 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL .::.: ..:.. ::: .. ... : . .. : .: ::. :::: NP_001 EGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTT---TAEREIVRD-------IKEKL 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR : : ::. . ...: :. ::.:.: : ::.: NP_001 -----------CY-VALDFEQEMATAASSSSLEK--------SYELPDGQVITIGNERFR 220 230 240 250 310 320 330 340 350 360 pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR ::.::.:: . : :. ... .:: ::.::: ::......::.:. :..:: NP_001 CPEALFQPS----FLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADR 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC ...:.. .: .:..:.:: :::.: ::::::::::.::::::::::::.:.: . NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI 320 330 340 350 360 pF1KB6 VERKCP :.::: NP_001 VHRKCF 370 >>NP_001186883 (OMIM: 102560,604717,614583) actin, cytop (375 aa) initn: 884 init1: 318 opt: 451 Z-score: 552.5 bits: 111.1 E(85289): 4.9e-24 Smith-Waterman score: 867; 36.9% identity (64.7% similar) in 417 aa overlap (9-425:3-374) 10 20 30 40 50 60 pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK .:..:::.: :: .::.::.: :.: ::. :: .. : . :.:.. NP_001 MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS .. .: . : . :...:.. .:. .. : ::. .... :. ::::.. NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLT 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH ::: : .:.:::.:..::: .: ::... :::. .:.::.::.:.::: : ..:.. NP_001 EAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIY 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL .::.: ..:.. ::: .. ... : . .. : .: ::. :::: NP_001 EGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTT---TAEREIVRD-------IKEKL 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR : : ::. . ...: :. ::.:.: : ::.: NP_001 -----------CY-VALDFEQEMATAASSSSLEK--------SYELPDGQVITIGNERFR 220 230 240 250 310 320 330 340 350 360 pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR ::.::.:: . : :. ... .:: ::.::: ::......::.:. :..:: NP_001 CPEALFQPS----FLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADR 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC ...:.. .: .:..:.:: :::.: ::::::::::.::::::::::::.:.: . NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI 320 330 340 350 360 pF1KB6 VERKCP :.::: NP_001 VHRKCF 370 >>NP_001605 (OMIM: 102560,604717,614583) actin, cytoplas (375 aa) initn: 884 init1: 318 opt: 451 Z-score: 552.5 bits: 111.1 E(85289): 4.9e-24 Smith-Waterman score: 867; 36.9% identity (64.7% similar) in 417 aa overlap (9-425:3-374) 10 20 30 40 50 60 pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK .:..:::.: :: .::.::.: :.: ::. :: .. : . :.:.. NP_001 MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS .. .: . : . :...:.. .:. .. : ::. .... :. ::::.. NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLT 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH ::: : .:.:::.:..::: .: ::... :::. .:.::.::.:.::: : ..:.. NP_001 EAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIY 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL .::.: ..:.. ::: .. ... : . .. : .: ::. :::: NP_001 EGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTT---TAEREIVRD-------IKEKL 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR : : ::. . ...: :. ::.:.: : ::.: NP_001 -----------CY-VALDFEQEMATAASSSSLEK--------SYELPDGQVITIGNERFR 220 230 240 250 310 320 330 340 350 360 pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR ::.::.:: . : :. ... .:: ::.::: ::......::.:. :..:: NP_001 CPEALFQPS----FLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADR 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC ...:.. .: .:..:.:: :::.: ::::::::::.::::::::::::.:.: . NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI 320 330 340 350 360 pF1KB6 VERKCP :.::: NP_001 VHRKCF 370 >>NP_001606 (OMIM: 102545) actin, gamma-enteric smooth m (376 aa) initn: 861 init1: 316 opt: 445 Z-score: 545.2 bits: 109.7 E(85289): 1.3e-23 Smith-Waterman score: 852; 36.9% identity (63.8% similar) in 417 aa overlap (9-425:4-375) 10 20 30 40 50 60 pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK .:. ::: : :: .::.::.: :.: ::. :: .. : . :.:.. NP_001 MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS .. .: . : . :...:.: .:. .. : :.. .... :. ::.:.. NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLT 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH ::: : .:.:::.:..::: .:.::... :::. .:.::.::.::::: : .:.. NP_001 EAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIY 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL .::.: ..:.. ::: .. ... : . ... : .: ::. :::: NP_001 EGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVT---TAEREIVRD-------IKEKL 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR : : ::. . ...: :. ::.:.: : ::.: NP_001 -----------CY-VALDFENEMATAASSSSLEK--------SYELPDGQVITIGNERFR 220 230 240 250 310 320 330 340 350 360 pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR :: ::.:: . : :. ... .:: :::::: ::.. ...::.:. :..:: NP_001 CPETLFQPSFI----GMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADR 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC ...:.. .: .:..:.:: :::.: ::::::::::.::::::::: ::.:.: . NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSI 320 330 340 350 360 370 pF1KB6 VERKCP :.::: NP_001 VHRKCF 426 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:19:40 2016 done: Sat Nov 5 11:19:41 2016 Total Scan time: 7.850 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]