FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6674, 454 aa 1>>>pF1KB6674 454 - 454 aa - 454 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8837+/-0.00105; mu= -5.6808+/- 0.063 mean_var=423.4347+/-86.284, 0's: 0 Z-trim(116.1): 28 B-trim: 181 in 1/53 Lambda= 0.062328 statistics sampled from 16663 (16687) to 16663 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.513), width: 16 Scan time: 3.010 The best scores are: opt bits E(32554) CCDS13035.1 PCED1A gene_id:64773|Hs108|chr20 ( 454) 3317 312.2 6.8e-85 CCDS59442.1 PCED1A gene_id:64773|Hs108|chr20 ( 403) 2542 242.5 6e-64 CCDS8752.1 PCED1B gene_id:91523|Hs108|chr12 ( 432) 1258 127.1 3.6e-29 >>CCDS13035.1 PCED1A gene_id:64773|Hs108|chr20 (454 aa) initn: 3317 init1: 3317 opt: 3317 Z-score: 1637.6 bits: 312.2 E(32554): 6.8e-85 Smith-Waterman score: 3317; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KB6 MVFCLSSEEPRRPLRSDMVHFQASEVQQLLHNKFVVILGDSIQRAVYKDLVLLLQKDSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MVFCLSSEEPRRPLRSDMVHFQASEVQQLLHNKFVVILGDSIQRAVYKDLVLLLQKDSLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TAAQLKAKGELSFEQDQLVAGGQLGELHNGTQYREVRQFCSGSGHHLVRFYFLTRVYSEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TAAQLKAKGELSFEQDQLVAGGQLGELHNGTQYREVRQFCSGSGHHLVRFYFLTRVYSEY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LEDVLEELTYGPAPDLVIINSCLWDLSRYGRCSMESYRENLERVFVRMDQVLPDSCLLVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LEDVLEELTYGPAPDLVIINSCLWDLSRYGRCSMESYRENLERVFVRMDQVLPDSCLLVW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NMAMPLGERITGGFLLPELQPLAGSLRRDVVEGNFYSATLAGDHCFDVLDLHFHFRHAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NMAMPLGERITGGFLLPELQPLAGSLRRDVVEGNFYSATLAGDHCFDVLDLHFHFRHAVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 HRHRDGVHWDQHAHRHLSHLLLTHVADAWGVELPKRGYPPDPWIEDWAEMNHPFQGSHRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 HRHRDGVHWDQHAHRHLSHLLLTHVADAWGVELPKRGYPPDPWIEDWAEMNHPFQGSHRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TPDFGEHLALLPPPPSSLPPPMPFPYPLPQPSPPPLFPPLPQDTPFFPGQPFPPHEFFNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TPDFGEHLALLPPPPSSLPPPMPFPYPLPQPSPPPLFPPLPQDTPFFPGQPFPPHEFFNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 NPVEDFSMPPHLGCGPGVNFVPGPLPPPIPGPNPHGQHWGPVVHRGMPRYVPNSPYHVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NPVEDFSMPPHLGCGPGVNFVPGPLPPPIPGPNPHGQHWGPVVHRGMPRYVPNSPYHVRR 370 380 390 400 410 420 430 440 450 pF1KB6 MGGPCRQRLRHSERLIHTYKLDRRPPAHSGTWPG :::::::::::::::::::::::::::::::::: CCDS13 MGGPCRQRLRHSERLIHTYKLDRRPPAHSGTWPG 430 440 450 >>CCDS59442.1 PCED1A gene_id:64773|Hs108|chr20 (403 aa) initn: 2542 init1: 2542 opt: 2542 Z-score: 1261.6 bits: 242.5 E(32554): 6e-64 Smith-Waterman score: 2857; 88.8% identity (88.8% similar) in 454 aa overlap (1-454:1-403) 10 20 30 40 50 60 pF1KB6 MVFCLSSEEPRRPLRSDMVHFQASEVQQLLHNKFVVILGDSIQRAVYKDLVLLLQKDSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MVFCLSSEEPRRPLRSDMVHFQASEVQQLLHNKFVVILGDSIQRAVYKDLVLLLQKDSLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TAAQLKAKGELSFEQDQLVAGGQLGELHNGTQYREVRQFCSGSGHHLVRFYFLTRVYSEY :::::::: : CCDS59 TAAQLKAK---------------------------------------------------Y 130 140 150 160 170 180 pF1KB6 LEDVLEELTYGPAPDLVIINSCLWDLSRYGRCSMESYRENLERVFVRMDQVLPDSCLLVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LEDVLEELTYGPAPDLVIINSCLWDLSRYGRCSMESYRENLERVFVRMDQVLPDSCLLVW 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB6 NMAMPLGERITGGFLLPELQPLAGSLRRDVVEGNFYSATLAGDHCFDVLDLHFHFRHAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 NMAMPLGERITGGFLLPELQPLAGSLRRDVVEGNFYSATLAGDHCFDVLDLHFHFRHAVQ 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB6 HRHRDGVHWDQHAHRHLSHLLLTHVADAWGVELPKRGYPPDPWIEDWAEMNHPFQGSHRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 HRHRDGVHWDQHAHRHLSHLLLTHVADAWGVELPKRGYPPDPWIEDWAEMNHPFQGSHRQ 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB6 TPDFGEHLALLPPPPSSLPPPMPFPYPLPQPSPPPLFPPLPQDTPFFPGQPFPPHEFFNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 TPDFGEHLALLPPPPSSLPPPMPFPYPLPQPSPPPLFPPLPQDTPFFPGQPFPPHEFFNY 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB6 NPVEDFSMPPHLGCGPGVNFVPGPLPPPIPGPNPHGQHWGPVVHRGMPRYVPNSPYHVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 NPVEDFSMPPHLGCGPGVNFVPGPLPPPIPGPNPHGQHWGPVVHRGMPRYVPNSPYHVRR 310 320 330 340 350 360 430 440 450 pF1KB6 MGGPCRQRLRHSERLIHTYKLDRRPPAHSGTWPG :::::::::::::::::::::::::::::::::: CCDS59 MGGPCRQRLRHSERLIHTYKLDRRPPAHSGTWPG 370 380 390 400 >>CCDS8752.1 PCED1B gene_id:91523|Hs108|chr12 (432 aa) initn: 719 init1: 589 opt: 1258 Z-score: 637.2 bits: 127.1 E(32554): 3.6e-29 Smith-Waterman score: 1382; 54.4% identity (70.4% similar) in 439 aa overlap (18-434:1-421) 10 20 30 40 50 60 pF1KB6 MVFCLSSEEPRRPLRSDMVHFQASEVQQLLHNKFVVILGDSIQRAVYKDLVLLLQKDSLL :. ..::::.::::::::::::::..:::::::::::::: :: CCDS87 MILLRASEVRQLLHNKFVVILGDSVHRAVYKDLVLLLQKDRLL 10 20 30 40 70 80 90 100 110 120 pF1KB6 TAAQLKAKGELSFEQDQLVAGGQLGELHNGTQYREVRQFCSGSGHHLVRFYFLTRVYSEY : .::.:.:::.::::.:: ::: :..::: .:::::.: : ::::::::::::::.: CCDS87 TPGQLRARGELNFEQDELVDGGQRGHMHNGLNYREVREF--RSDHHLVRFYFLTRVYSDY 50 60 70 80 90 100 130 140 150 160 170 pF1KB6 LEDVLEELTYGP-APDLVIINSCLWDLSRYGRCSMESYRENLERVFVRMDQVLPDSCLLV :. .:.:: : ::::::.::::::.:::: : .:: :::: .: . ::::.::::: CCDS87 LQTILKELQSGEHAPDLVIMNSCLWDISRYGPNSWRSYLENLENLFQCLGQVLPESCLLV 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 WNMAMPLGERITGGFLLPELQPLAGS-LRRDVVEGNFYSATLAGDHCFDVLDLHFHFRHA :: :::.::..::::: :.:. .. :. .::..::.::: : : ::::::::::::: CCDS87 WNTAMPVGEEVTGGFLPPKLRRQKATFLKNEVVKANFHSATEARKHNFDVLDLHFHFRHA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 VQHRHRDGVHWDQHAHRHLSHLLLTHVADAWGVELPKRGYPPDPWIEDWA---EMNHPFQ .. : :::::. ..:: ::.:::.:::::::::::.: .: ::. ... : : CCDS87 RENLHWDGVHWNGRVHRCLSQLLLAHVADAWGVELPHR-HPVGEWIKKKKPGPRVEGPPQ 230 240 250 260 270 280 300 310 320 330 pF1KB6 GSHRQTPDFGEHLALLPPPPSSL--P----PPMPFPY-PL--PQPSPP-------PLFPP ..:. : : : :: :: : ::. .: :: ::: :: : :: CCDS87 -ANRNHPA----LPLSPPLPSPTYRPLLGFPPQRLPLLPLLSPQPPPPILHHQGMPRFPQ 290 300 310 320 330 340 350 360 370 380 390 pF1KB6 LPQDTPFFPGQPFPPHEFFNYNPVEDFSMPPHLGCGPGVNFVPGP-LPPPIPGPNPHGQH : :. : . : .:. .. : : : ::. :: :: :. :.:. :. CCDS87 GPPDACFSSDHTFQSDQFYCHS---DVPSSAHAGFFVEDNFMVGPQLPMPFF-PTPRYQR 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB6 WGPVVHRGMPRYVPNSPYHVRRMGGPCRQRLRHSERLIHTYKLDRRPPAHSGTWPG .::::::. :: : .:: : :: : :.: CCDS87 PAPVVHRGFGRYRPRGPYT------PWGQRPRPSKRRAPANPEPRPQ 400 410 420 430 454 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:42:46 2016 done: Sat Nov 5 11:42:47 2016 Total Scan time: 3.010 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]