FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6675, 427 aa 1>>>pF1KB6675 427 - 427 aa - 427 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6928+/-0.00033; mu= 12.2600+/- 0.021 mean_var=141.4854+/-27.807, 0's: 0 Z-trim(120.5): 120 B-trim: 47 in 1/52 Lambda= 0.107825 statistics sampled from 35571 (35714) to 35571 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.419), width: 16 Scan time: 7.630 The best scores are: opt bits E(85289) NP_002498 (OMIM: 162010) tumor necrosis factor rec ( 427) 2962 472.1 1.2e-132 XP_016857721 (OMIM: 600315,615593) PREDICTED: tumo ( 277) 304 58.5 2.5e-08 NP_003318 (OMIM: 600315,615593) tumor necrosis fac ( 277) 304 58.5 2.5e-08 XP_016857720 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 304 58.5 2.7e-08 XP_011540377 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 304 58.5 2.7e-08 NP_001289682 (OMIM: 109535,606843) tumor necrosis ( 237) 276 54.0 4.6e-07 XP_016883624 (OMIM: 109535,606843) PREDICTED: tumo ( 323) 276 54.2 5.8e-07 XP_016883626 (OMIM: 109535,606843) PREDICTED: tumo ( 222) 262 51.8 2e-06 NP_001241 (OMIM: 109535,606843) tumor necrosis fac ( 277) 262 51.9 2.3e-06 NP_001309350 (OMIM: 109535,606843) tumor necrosis ( 281) 262 51.9 2.4e-06 XP_016883625 (OMIM: 109535,606843) PREDICTED: tumo ( 289) 241 48.7 2.3e-05 NP_003814 (OMIM: 603361) tumor necrosis factor rec ( 300) 236 47.9 4.1e-05 XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399) 237 48.2 4.5e-05 NP_003832 (OMIM: 603613) tumor necrosis factor rec ( 259) 230 46.9 7e-05 XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255) 226 46.3 0.00011 NP_001257916 (OMIM: 600979) tumor necrosis factor ( 416) 225 46.3 0.00017 NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435) 225 46.4 0.00018 NP_001284534 (OMIM: 602746) tumor necrosis factor ( 184) 203 42.6 0.001 XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197) 203 42.6 0.0011 NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283) 203 42.8 0.0014 NP_002537 (OMIM: 239000,602643) tumor necrosis fac ( 401) 205 43.2 0.0014 NP_690610 (OMIM: 134637,601859) tumor necrosis fac ( 314) 198 42.0 0.0025 XP_011538067 (OMIM: 134637,601859) PREDICTED: tumo ( 368) 198 42.1 0.0029 NP_003831 (OMIM: 603614) tumor necrosis factor rec ( 386) 197 42.0 0.0033 NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461) 197 42.0 0.0037 XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462) 197 42.0 0.0038 XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484) 197 42.0 0.0039 XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491) 197 42.1 0.0039 NP_001307548 (OMIM: 134637,601859) tumor necrosis ( 197) 185 39.8 0.0074 NP_690611 (OMIM: 134637,601859) tumor necrosis fac ( 220) 185 39.9 0.008 >>NP_002498 (OMIM: 162010) tumor necrosis factor recepto (427 aa) initn: 2962 init1: 2962 opt: 2962 Z-score: 2502.6 bits: 472.1 E(85289): 1.2e-132 Smith-Waterman score: 2962; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB6 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QTVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QTVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLREC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLREC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTTVMGSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTTVMGSSQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 LHSDSGISVDSQSLHDQQPHTQTASGQALKGDGGLYSSLPPAKREEVEKLLNGSAGDTWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LHSDSGISVDSQSLHDQQPHTQTASGQALKGDGGLYSSLPPAKREEVEKLLNGSAGDTWR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 HLAGELGYQPEHIDSFTHEACPVRALLASWATQDSATLDALLAALRRIQRADLVESLCSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HLAGELGYQPEHIDSFTHEACPVRALLASWATQDSATLDALLAALRRIQRADLVESLCSE 370 380 390 400 410 420 pF1KB6 STATSPV ::::::: NP_002 STATSPV >>XP_016857721 (OMIM: 600315,615593) PREDICTED: tumor ne (277 aa) initn: 227 init1: 86 opt: 304 Z-score: 270.4 bits: 58.5 E(85289): 2.5e-08 Smith-Waterman score: 304; 32.9% identity (51.0% similar) in 249 aa overlap (1-237:3-229) 10 20 30 40 50 pF1KB6 MGAGATGRAMDGPRLLLLLL-LGVS-LGGAKEACPTGLYTHSGECCKACNLGEGVAQP .:: :: :: :::: ::.: . : . : : . .::. : :.:... XP_016 MCVGARRLGR---GPCAALLLLGLGLSTVTGLH--CVGDTYPSNDRCCHECRPGNGMVSR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAP---CVEADDAVCRCAYG :. .: :::.:: . ..:::: ..:::::: : .:.: : :. ..:.:::: : XP_016 CSRSQNTVCRPCGPGF-YNDVVS-SKPCKPCTWC-NLRSGSERKQLCTATQDTVCRCRAG 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 YYQDETTGRCEACRVCEAGSGLVFSCQDKQN----TVCEECPDGTYSDEANHVDPCLPCT .. : : : :: :.: : : : . .: : . XP_016 TQPLDSYKPGVDCAPCPPGH---FSPGDNQACKPWTNCTLAGKHTLQPASNSSD-----A 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 VCEDTERQLRECTRWADAECEEIPGRWITRSTPPEG--SDSTAPSTQEPEAPPEQDLIAS .::: :. : . :.: :: . : :. : .:::. :.: . . : XP_016 ICED-----RDPPATQPQETQGPPARPITVQ-PTEAWPRTSQGPSTRPVEVPGGRAVAAI 170 180 190 200 210 230 240 250 260 270 280 pF1KB6 TVAGVVTTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGAN :.: ..: XP_016 LGLGLVLGLLGPLAILLALYLLRRDQRLPPDAHKPPGGGSFRTPIQEEQADAHSTLAKI 220 230 240 250 260 270 >>NP_003318 (OMIM: 600315,615593) tumor necrosis factor (277 aa) initn: 227 init1: 86 opt: 304 Z-score: 270.4 bits: 58.5 E(85289): 2.5e-08 Smith-Waterman score: 304; 32.9% identity (51.0% similar) in 249 aa overlap (1-237:3-229) 10 20 30 40 50 pF1KB6 MGAGATGRAMDGPRLLLLLL-LGVS-LGGAKEACPTGLYTHSGECCKACNLGEGVAQP .:: :: :: :::: ::.: . : . : : . .::. : :.:... NP_003 MCVGARRLGR---GPCAALLLLGLGLSTVTGLH--CVGDTYPSNDRCCHECRPGNGMVSR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAP---CVEADDAVCRCAYG :. .: :::.:: . ..:::: ..:::::: : .:.: : :. ..:.:::: : NP_003 CSRSQNTVCRPCGPGF-YNDVVS-SKPCKPCTWC-NLRSGSERKQLCTATQDTVCRCRAG 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 YYQDETTGRCEACRVCEAGSGLVFSCQDKQN----TVCEECPDGTYSDEANHVDPCLPCT .. : : : :: :.: : : : . .: : . NP_003 TQPLDSYKPGVDCAPCPPGH---FSPGDNQACKPWTNCTLAGKHTLQPASNSSD-----A 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 VCEDTERQLRECTRWADAECEEIPGRWITRSTPPEG--SDSTAPSTQEPEAPPEQDLIAS .::: :. : . :.: :: . : :. : .:::. :.: . . : NP_003 ICED-----RDPPATQPQETQGPPARPITVQ-PTEAWPRTSQGPSTRPVEVPGGRAVAAI 170 180 190 200 210 230 240 250 260 270 280 pF1KB6 TVAGVVTTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGAN :.: ..: NP_003 LGLGLVLGLLGPLAILLALYLLRRDQRLPPDAHKPPGGGSFRTPIQEEQADAHSTLAKI 220 230 240 250 260 270 >>XP_016857720 (OMIM: 600315,615593) PREDICTED: tumor ne (303 aa) initn: 193 init1: 86 opt: 304 Z-score: 269.9 bits: 58.5 E(85289): 2.7e-08 Smith-Waterman score: 304; 32.9% identity (51.0% similar) in 249 aa overlap (1-237:3-229) 10 20 30 40 50 pF1KB6 MGAGATGRAMDGPRLLLLLL-LGVS-LGGAKEACPTGLYTHSGECCKACNLGEGVAQP .:: :: :: :::: ::.: . : . : : . .::. : :.:... XP_016 MCVGARRLGR---GPCAALLLLGLGLSTVTGLH--CVGDTYPSNDRCCHECRPGNGMVSR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAP---CVEADDAVCRCAYG :. .: :::.:: . ..:::: ..:::::: : .:.: : :. ..:.:::: : XP_016 CSRSQNTVCRPCGPGF-YNDVVS-SKPCKPCTWC-NLRSGSERKQLCTATQDTVCRCRAG 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 YYQDETTGRCEACRVCEAGSGLVFSCQDKQN----TVCEECPDGTYSDEANHVDPCLPCT .. : : : :: :.: : : : . .: : . XP_016 TQPLDSYKPGVDCAPCPPGH---FSPGDNQACKPWTNCTLAGKHTLQPASNSSD-----A 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 VCEDTERQLRECTRWADAECEEIPGRWITRSTPPEG--SDSTAPSTQEPEAPPEQDLIAS .::: :. : . :.: :: . : :. : .:::. :.: . . : XP_016 ICED-----RDPPATQPQETQGPPARPITVQ-PTEAWPRTSQGPSTRPVEVPGGRAVAAI 170 180 190 200 210 230 240 250 260 270 280 pF1KB6 TVAGVVTTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGAN :.: ..: XP_016 LGLGLVLGLLGPLAILLALYLLRRDQRLPPDAHKPPGECLMALPHCSWRVRPTHQSLLFS 220 230 240 250 260 270 >>XP_011540377 (OMIM: 600315,615593) PREDICTED: tumor ne (303 aa) initn: 193 init1: 86 opt: 304 Z-score: 269.9 bits: 58.5 E(85289): 2.7e-08 Smith-Waterman score: 304; 32.9% identity (51.0% similar) in 249 aa overlap (1-237:3-229) 10 20 30 40 50 pF1KB6 MGAGATGRAMDGPRLLLLLL-LGVS-LGGAKEACPTGLYTHSGECCKACNLGEGVAQP .:: :: :: :::: ::.: . : . : : . .::. : :.:... XP_011 MCVGARRLGR---GPCAALLLLGLGLSTVTGLH--CVGDTYPSNDRCCHECRPGNGMVSR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAP---CVEADDAVCRCAYG :. .: :::.:: . ..:::: ..:::::: : .:.: : :. ..:.:::: : XP_011 CSRSQNTVCRPCGPGF-YNDVVS-SKPCKPCTWC-NLRSGSERKQLCTATQDTVCRCRAG 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 YYQDETTGRCEACRVCEAGSGLVFSCQDKQN----TVCEECPDGTYSDEANHVDPCLPCT .. : : : :: :.: : : : . .: : . XP_011 TQPLDSYKPGVDCAPCPPGH---FSPGDNQACKPWTNCTLAGKHTLQPASNSSD-----A 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 VCEDTERQLRECTRWADAECEEIPGRWITRSTPPEG--SDSTAPSTQEPEAPPEQDLIAS .::: :. : . :.: :: . : :. : .:::. :.: . . : XP_011 ICED-----RDPPATQPQETQGPPARPITVQ-PTEAWPRTSQGPSTRPVEVPGGRAVAAI 170 180 190 200 210 230 240 250 260 270 280 pF1KB6 TVAGVVTTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGAN :.: ..: XP_011 LGLGLVLGLLGPLAILLALYLLRRDQRLPPDAHKPPGECLMALPHCSWRVRPTHQSLLFS 220 230 240 250 260 270 >>NP_001289682 (OMIM: 109535,606843) tumor necrosis fact (237 aa) initn: 99 init1: 99 opt: 276 Z-score: 247.7 bits: 54.0 E(85289): 4.6e-07 Smith-Waterman score: 276; 27.6% identity (51.3% similar) in 199 aa overlap (31-221:25-214) 10 20 30 40 50 pF1KB6 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA- :: : ...::. :. :. ... : NP_001 MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEF 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 NQTVCEPCLDSVTFSDVVSATEPC---KPCTECVGLQSMSAPCVEADDAVCRCAYGYYQD ..: : :: .: : :. . : : : .::. .. :.: ..: : :.. NP_001 TETECLPCGES-EFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETD-TICTCEEGWH-- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ETTGRCEAC---RVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDT :. ::.: : : : :. ..:.:: :: : .:. .. . : : : :: NP_001 CTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 ERQLREC-TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVV . ... : .:. : : : : :. . :.. : . :.. NP_001 DLVVQQAGTNKTDVVCGE---SWTM--GPGESLGRSPGSAESPGGDPHHLRDPVCHPLGA 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 TTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQ NP_001 GLYQKGGQEANQ 230 >>XP_016883624 (OMIM: 109535,606843) PREDICTED: tumor ne (323 aa) initn: 176 init1: 99 opt: 276 Z-score: 246.0 bits: 54.2 E(85289): 5.8e-07 Smith-Waterman score: 278; 26.0% identity (48.7% similar) in 269 aa overlap (31-289:25-274) 10 20 30 40 50 pF1KB6 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA- :: : ...::. :. :. ... : XP_016 MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEF 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 NQTVCEPCLDSVTFSDVVSATEPC---KPCTECVGLQSMSAPCVEADDAVCRCAYGYYQD ..: : :: .: : :. . : : : .::. .. :.: ..: : :.. XP_016 TETECLPCGES-EFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETD-TICTCEEGWH-- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ETTGRCEAC---RVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDT :. ::.: : : : :. ..:.:: :: : .:. .. . : : : :: XP_016 CTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 ERQLREC-TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQ--DLIASTVAG . ... : .:. : : : : :. . :.. : . :.. : . . : XP_016 DLVVQQAGTNKTDVVCGE---SWTM--GPGESLGRSPGSAESPGGDPHHLRDPVCHPL-G 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 VVTTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPV . :::. : : . : ::. .. ..: .:.. . :: : XP_016 AGLYQWPRSQPI--RPPTPSRNPRR-SIFPTI------FLAPTLLLQCRRLYMDANRSPR 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 NQTPPPEGEKLHSDSGISVDSQSLHDQQPHTQTASGQALKGDGGLYSSLPPAKREEVEKL XP_016 RMAKRVASQCRRDSEAAPTQECGHVGKQAVGQRAWCCCCCGVRVRGWH 280 290 300 310 320 >>XP_016883626 (OMIM: 109535,606843) PREDICTED: tumor ne (222 aa) initn: 126 init1: 99 opt: 262 Z-score: 236.3 bits: 51.8 E(85289): 2e-06 Smith-Waterman score: 262; 28.9% identity (53.0% similar) in 166 aa overlap (31-188:25-186) 10 20 30 40 50 pF1KB6 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA- :: : ...::. :. :. ... : XP_016 MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEF 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 NQTVCEPCLDSVTFSDVVSATEPC---KPCTECVGLQSMSAPCVEADDAVCRCAYGYYQD ..: : :: .: : :. . : : : .::. .. :.: ..: : :.. XP_016 TETECLPCGES-EFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETD-TICTCEEGWHC- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ETTGRCEAC---RVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDT :. ::.: : : : :. ..:.:: :: : .:. .. . : : : :: XP_016 -TSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 ERQLREC-TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVV . ... : .:. : XP_016 DLVVQQAGTNKTDVVCGPQDRLRALVVIPIIFGILFAILLVLVFISGQEANQ 180 190 200 210 220 >>NP_001241 (OMIM: 109535,606843) tumor necrosis factor (277 aa) initn: 152 init1: 99 opt: 262 Z-score: 235.1 bits: 51.9 E(85289): 2.3e-06 Smith-Waterman score: 262; 28.9% identity (53.0% similar) in 166 aa overlap (31-188:25-186) 10 20 30 40 50 pF1KB6 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA- :: : ...::. :. :. ... : NP_001 MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEF 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 NQTVCEPCLDSVTFSDVVSATEPC---KPCTECVGLQSMSAPCVEADDAVCRCAYGYYQD ..: : :: .: : :. . : : : .::. .. :.: ..: : :.. NP_001 TETECLPCGES-EFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETD-TICTCEEGWHC- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ETTGRCEAC---RVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDT :. ::.: : : : :. ..:.:: :: : .:. .. . : : : :: NP_001 -TSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 ERQLREC-TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVV . ... : .:. : NP_001 DLVVQQAGTNKTDVVCGPQDRLRALVVIPIIFGILFAILLVLVFIKKVAKKPTNKAPHPK 180 190 200 210 220 230 >>NP_001309350 (OMIM: 109535,606843) tumor necrosis fact (281 aa) initn: 181 init1: 99 opt: 262 Z-score: 235.0 bits: 51.9 E(85289): 2.4e-06 Smith-Waterman score: 262; 28.9% identity (53.0% similar) in 166 aa overlap (31-188:25-186) 10 20 30 40 50 pF1KB6 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA- :: : ...::. :. :. ... : NP_001 MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEF 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 NQTVCEPCLDSVTFSDVVSATEPC---KPCTECVGLQSMSAPCVEADDAVCRCAYGYYQD ..: : :: .: : :. . : : : .::. .. :.: ..: : :.. NP_001 TETECLPCGES-EFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETD-TICTCEEGWHC- 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ETTGRCEAC---RVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDT :. ::.: : : : :. ..:.:: :: : .:. .. . : : : :: NP_001 -TSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 ERQLREC-TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVV . ... : .:. : NP_001 DLVVQQAGTNKTDVVCGPQDRLRALVVIPIIFGILFAILLVLVFISESSEKVAKKPTNKA 180 190 200 210 220 230 427 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 20:20:31 2016 done: Mon Nov 7 20:20:32 2016 Total Scan time: 7.630 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]