FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6679, 427 aa 1>>>pF1KB6679 427 - 427 aa - 427 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7084+/-0.000365; mu= 16.2481+/- 0.023 mean_var=114.5989+/-24.078, 0's: 0 Z-trim(115.4): 125 B-trim: 0 in 0/53 Lambda= 0.119807 statistics sampled from 25717 (25861) to 25717 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.303), width: 16 Scan time: 9.070 The best scores are: opt bits E(85289) NP_000098 (OMIM: 278740,600811) DNA damage-binding ( 427) 2966 523.9 3e-148 NP_001287663 (OMIM: 278740,600811) DNA damage-bind ( 238) 1061 194.4 2.7e-49 NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 224 49.9 1.3e-05 XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 219 49.3 3.5e-05 XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 219 49.3 3.5e-05 NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 219 49.3 3.5e-05 XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 219 49.3 3.5e-05 XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 219 49.3 3.5e-05 XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 219 49.3 3.5e-05 XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 219 49.3 3.5e-05 XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 219 49.3 3.5e-05 XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 219 49.3 3.5e-05 XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 219 49.3 3.5e-05 XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 219 49.3 3.5e-05 XP_011527969 (OMIM: 601475) PREDICTED: periodic tr ( 734) 194 45.0 0.00075 NP_005040 (OMIM: 601475) periodic tryptophan prote ( 919) 194 45.1 0.00087 NP_001290177 (OMIM: 609540) WD repeat-containing p ( 212) 171 40.5 0.005 NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 171 40.6 0.0061 NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 171 40.6 0.0061 NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 171 40.9 0.0093 NP_004688 (OMIM: 607795,615922) U4/U6 small nuclea ( 522) 171 40.9 0.0093 >>NP_000098 (OMIM: 278740,600811) DNA damage-binding pro (427 aa) initn: 2966 init1: 2966 opt: 2966 Z-score: 2782.5 bits: 523.9 E(85289): 3e-148 Smith-Waterman score: 2966; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB6 MAPKKRPETQKTSEIVLRPRNKRSRSPLELEPEAKKLCAKGSGPSRRCDSDCLWVGLAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MAPKKRPETQKTSEIVLRPRNKRSRSPLELEPEAKKLCAKGSGPSRRCDSDCLWVGLAGP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QILPPCRSIVRTLHQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QILPPCRSIVRTLHQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PTHPSTVAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSMEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PTHPSTVAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSMEGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TRLQDFKGNILRVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKELWNLRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TRLQDFKGNILRVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKELWNLRM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 HKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLPHRHPVNAACFSPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLPHRHPVNAACFSPDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 ARLLTTDQKSEIRVYSASQWDCPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ARLLTTDQKSEIRVYSASQWDCPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 FKSCTPYELRTIDVFDGNSGKMMCQLYDPESSGISSLNEFNPMGDTLASAMGYHILIWSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FKSCTPYELRTIDVFDGNSGKMMCQLYDPESSGISSLNEFNPMGDTLASAMGYHILIWSQ 370 380 390 400 410 420 pF1KB6 EEARTRK ::::::: NP_000 EEARTRK >>NP_001287663 (OMIM: 278740,600811) DNA damage-binding (238 aa) initn: 1650 init1: 1061 opt: 1061 Z-score: 1006.1 bits: 194.4 E(85289): 2.7e-49 Smith-Waterman score: 1276; 55.7% identity (55.7% similar) in 427 aa overlap (1-427:1-238) 10 20 30 40 50 60 pF1KB6 MAPKKRPETQKTSEIVLRPRNKRSRSPLELEPEAKKLCAKGSGPSRRCDSDCLWVGLAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAPKKRPETQKTSEIVLRPRNKRSRSPLELEPEAKKLCAKGSGPSRRCDSDCLWVGLAGP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QILPPCRSIVRTLHQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QILPPCRSIVRTLHQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PTHPSTVAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSMEGT :::::::::::::::::::::::::::::::: NP_001 PTHPSTVAVGSKGGDIMLWNFGIKDKPTFIKG---------------------------- 130 140 150 190 200 210 220 230 240 pF1KB6 TRLQDFKGNILRVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKELWNLRM NP_001 ------------------------------------------------------------ 250 260 270 280 290 300 pF1KB6 HKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLPHRHPVNAACFSPDG NP_001 ------------------------------------------------------------ 310 320 330 340 350 360 pF1KB6 ARLLTTDQKSEIRVYSASQWDCPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPN ::::::::::::::::::: NP_001 -----------------------------------------AAWHPRYNLIVVGRYPDPN 160 170 370 380 390 400 410 420 pF1KB6 FKSCTPYELRTIDVFDGNSGKMMCQLYDPESSGISSLNEFNPMGDTLASAMGYHILIWSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKSCTPYELRTIDVFDGNSGKMMCQLYDPESSGISSLNEFNPMGDTLASAMGYHILIWSQ 180 190 200 210 220 230 pF1KB6 EEARTRK ::::::: NP_001 EEARTRK >>NP_004805 (OMIM: 607797) U5 small nuclear ribonucleopr (357 aa) initn: 144 init1: 70 opt: 224 Z-score: 222.0 bits: 49.9 E(85289): 1.3e-05 Smith-Waterman score: 232; 24.0% identity (52.3% similar) in 367 aa overlap (59-410:9-345) 30 40 50 60 70 80 pF1KB6 ELEPEAKKLCAKGSGPSRRCDSDCLWVGLAGPQILPPCRSIVRTLHQHKLGRASWPSV-Q ::.. : . : :. :: .: :.. : NP_004 MIEQQKRKGPEL--PLVPVKRQRHELLLGAGSGPGAGQ 10 20 30 90 100 110 120 130 140 pF1KB6 QGLQQSFLHTLDSYRILQKAAP---FDRRATSLAWHPTHPSTVAVGSKGGD--IMLWN-F : . : : . :: .. . . ::. ...: : : :.::: . NP_004 QQATPGALLQAGPPRCSSLQAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVY 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 GIKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKGN-ILRVFASSDTI : :. . .:: .:.. :..: .. : ::. . .. .. :. . :. . .. . NP_004 GDCDNYATLKG--HSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFV 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 NIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKELWNLRMHKKKVTHVALNPCCDWFLAT : : . . ..: ::.. :.: : .. : . .. .: :..: : .. . NP_004 N--SC-YPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQII-S 160 170 180 190 200 210 270 280 290 300 310 pF1KB6 ASVDQTVKIWDLRQVRGKASFLYSL-PHRHPVNAACFSPDGARLLTTDQKSEIRVYS--- ...:. .:.::::: . . :.. : :.. .: .:. ::.. . . .::.. NP_004 GGIDNDIKVWDLRQNK----LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRP 220 230 240 250 260 320 330 340 350 360 370 pF1KB6 -ASQWDCPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTPYELRTIDVF : . : . . : ..: .. .: : . :..: : : . :. NP_004 FAPKERCVKIFQGNVHNFEKNL--LRCSWSPDGSKIAAGS-AD-----------RFVYVW 270 280 290 300 310 380 390 400 410 420 pF1KB6 DGNSGKMMCQLYDPESSGISSLNE--FNPMGDTLASAMGYHILIWSQEEARTRK : .: ... .: : .: :.:: :.: . :: NP_004 DTTSRRILYKL--PGHAG--SINEVAFHPDEPIIISASSDKRLYMGEIQ 320 330 340 350 >>XP_016878353 (OMIM: 602703,616212) PREDICTED: katanin (655 aa) initn: 166 init1: 80 opt: 219 Z-score: 214.1 bits: 49.3 E(85289): 3.5e-05 Smith-Waterman score: 219; 27.1% identity (57.2% similar) in 236 aa overlap (104-332:13-235) 80 90 100 110 120 130 pF1KB6 HQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWHPTHPSTVAVGSKG ::. . ..::. . .:.:. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDD 10 20 30 40 140 150 160 170 180 190 pF1KB6 GDIMLWNFGIKDKPTFIKGI-GAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKG-NIL . ::.. .::. : .. : . . ....: . . :.:. :. :. :... .:: XP_016 CRVNLWSI---NKPNCIMSLTGHTSPVESVRLNT-PEELIVAGSQSGSIRVWDLEAAKIL 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 RVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKE-LWNLRMHKKKVTHVAL :.. . . :: :::: ...:..:.. :. : .. : .. : :.. : . . XP_016 RTLMGHKA-NI--CSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 NPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLP-HRHPVNAACFSPDGARLLTTDQK .: : ::.:. :.:::.::: :: .. .: : :::.. : :. : . .. XP_016 SPDGKW-LASAADDHTVKLWDLTA--GK--MMSEFPGHTGPVNVVEFHPNEYLLASGSSD 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 SEIRVYSASQWD---CPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTP :: .. ... : : : : : XP_016 RTIRFWDLEKFQVVSCIEGE-PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVL 220 230 240 250 260 >>XP_016878352 (OMIM: 602703,616212) PREDICTED: katanin (655 aa) initn: 166 init1: 80 opt: 219 Z-score: 214.1 bits: 49.3 E(85289): 3.5e-05 Smith-Waterman score: 219; 27.1% identity (57.2% similar) in 236 aa overlap (104-332:13-235) 80 90 100 110 120 130 pF1KB6 HQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWHPTHPSTVAVGSKG ::. . ..::. . .:.:. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDD 10 20 30 40 140 150 160 170 180 190 pF1KB6 GDIMLWNFGIKDKPTFIKGI-GAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKG-NIL . ::.. .::. : .. : . . ....: . . :.:. :. :. :... .:: XP_016 CRVNLWSI---NKPNCIMSLTGHTSPVESVRLNT-PEELIVAGSQSGSIRVWDLEAAKIL 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 RVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKE-LWNLRMHKKKVTHVAL :.. . . :: :::: ...:..:.. :. : .. : .. : :.. : . . XP_016 RTLMGHKA-NI--CSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 NPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLP-HRHPVNAACFSPDGARLLTTDQK .: : ::.:. :.:::.::: :: .. .: : :::.. : :. : . .. XP_016 SPDGKW-LASAADDHTVKLWDLTA--GK--MMSEFPGHTGPVNVVEFHPNEYLLASGSSD 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 SEIRVYSASQWD---CPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTP :: .. ... : : : : : XP_016 RTIRFWDLEKFQVVSCIEGE-PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVL 220 230 240 250 260 >>NP_005877 (OMIM: 602703,616212) katanin p80 WD40 repea (655 aa) initn: 166 init1: 80 opt: 219 Z-score: 214.1 bits: 49.3 E(85289): 3.5e-05 Smith-Waterman score: 219; 27.1% identity (57.2% similar) in 236 aa overlap (104-332:13-235) 80 90 100 110 120 130 pF1KB6 HQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWHPTHPSTVAVGSKG ::. . ..::. . .:.:. NP_005 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDD 10 20 30 40 140 150 160 170 180 190 pF1KB6 GDIMLWNFGIKDKPTFIKGI-GAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKG-NIL . ::.. .::. : .. : . . ....: . . :.:. :. :. :... .:: NP_005 CRVNLWSI---NKPNCIMSLTGHTSPVESVRLNT-PEELIVAGSQSGSIRVWDLEAAKIL 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 RVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKE-LWNLRMHKKKVTHVAL :.. . . :: :::: ...:..:.. :. : .. : .. : :.. : . . NP_005 RTLMGHKA-NI--CSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 NPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLP-HRHPVNAACFSPDGARLLTTDQK .: : ::.:. :.:::.::: :: .. .: : :::.. : :. : . .. NP_005 SPDGKW-LASAADDHTVKLWDLTA--GK--MMSEFPGHTGPVNVVEFHPNEYLLASGSSD 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 SEIRVYSASQWD---CPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTP :: .. ... : : : : : NP_005 RTIRFWDLEKFQVVSCIEGE-PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVL 220 230 240 250 260 >>XP_006721186 (OMIM: 602703,616212) PREDICTED: katanin (658 aa) initn: 166 init1: 80 opt: 219 Z-score: 214.1 bits: 49.3 E(85289): 3.5e-05 Smith-Waterman score: 219; 27.1% identity (57.2% similar) in 236 aa overlap (104-332:13-235) 80 90 100 110 120 130 pF1KB6 HQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWHPTHPSTVAVGSKG ::. . ..::. . .:.:. XP_006 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDD 10 20 30 40 140 150 160 170 180 190 pF1KB6 GDIMLWNFGIKDKPTFIKGI-GAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKG-NIL . ::.. .::. : .. : . . ....: . . :.:. :. :. :... .:: XP_006 CRVNLWSI---NKPNCIMSLTGHTSPVESVRLNT-PEELIVAGSQSGSIRVWDLEAAKIL 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 RVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKE-LWNLRMHKKKVTHVAL :.. . . :: :::: ...:..:.. :. : .. : .. : :.. : . . XP_006 RTLMGHKA-NI--CSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 NPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLP-HRHPVNAACFSPDGARLLTTDQK .: : ::.:. :.:::.::: :: .. .: : :::.. : :. : . .. XP_006 SPDGKW-LASAADDHTVKLWDLTA--GK--MMSEFPGHTGPVNVVEFHPNEYLLASGSSD 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 SEIRVYSASQWD---CPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTP :: .. ... : : : : : XP_006 RTIRFWDLEKFQVVSCIEGE-PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVL 220 230 240 250 260 >>XP_016878350 (OMIM: 602703,616212) PREDICTED: katanin (672 aa) initn: 166 init1: 80 opt: 219 Z-score: 214.0 bits: 49.3 E(85289): 3.5e-05 Smith-Waterman score: 219; 27.1% identity (57.2% similar) in 236 aa overlap (104-332:13-235) 80 90 100 110 120 130 pF1KB6 HQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWHPTHPSTVAVGSKG ::. . ..::. . .:.:. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDD 10 20 30 40 140 150 160 170 180 190 pF1KB6 GDIMLWNFGIKDKPTFIKGI-GAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKG-NIL . ::.. .::. : .. : . . ....: . . :.:. :. :. :... .:: XP_016 CRVNLWSI---NKPNCIMSLTGHTSPVESVRLNT-PEELIVAGSQSGSIRVWDLEAAKIL 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 RVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKE-LWNLRMHKKKVTHVAL :.. . . :: :::: ...:..:.. :. : .. : .. : :.. : . . XP_016 RTLMGHKA-NI--CSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 NPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLP-HRHPVNAACFSPDGARLLTTDQK .: : ::.:. :.:::.::: :: .. .: : :::.. : :. : . .. XP_016 SPDGKW-LASAADDHTVKLWDLTA--GK--MMSEFPGHTGPVNVVEFHPNEYLLASGSSD 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 SEIRVYSASQWD---CPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTP :: .. ... : : : : : XP_016 RTIRFWDLEKFQVVSCIEGE-PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVL 220 230 240 250 260 >>XP_005255829 (OMIM: 602703,616212) PREDICTED: katanin (672 aa) initn: 166 init1: 80 opt: 219 Z-score: 214.0 bits: 49.3 E(85289): 3.5e-05 Smith-Waterman score: 219; 27.1% identity (57.2% similar) in 236 aa overlap (104-332:13-235) 80 90 100 110 120 130 pF1KB6 HQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWHPTHPSTVAVGSKG ::. . ..::. . .:.:. XP_005 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDD 10 20 30 40 140 150 160 170 180 190 pF1KB6 GDIMLWNFGIKDKPTFIKGI-GAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKG-NIL . ::.. .::. : .. : . . ....: . . :.:. :. :. :... .:: XP_005 CRVNLWSI---NKPNCIMSLTGHTSPVESVRLNT-PEELIVAGSQSGSIRVWDLEAAKIL 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 RVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKE-LWNLRMHKKKVTHVAL :.. . . :: :::: ...:..:.. :. : .. : .. : :.. : . . XP_005 RTLMGHKA-NI--CSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 NPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLP-HRHPVNAACFSPDGARLLTTDQK .: : ::.:. :.:::.::: :: .. .: : :::.. : :. : . .. XP_005 SPDGKW-LASAADDHTVKLWDLTA--GK--MMSEFPGHTGPVNVVEFHPNEYLLASGSSD 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 SEIRVYSASQWD---CPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTP :: .. ... : : : : : XP_005 RTIRFWDLEKFQVVSCIEGE-PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVL 220 230 240 250 260 >>XP_016878351 (OMIM: 602703,616212) PREDICTED: katanin (672 aa) initn: 166 init1: 80 opt: 219 Z-score: 214.0 bits: 49.3 E(85289): 3.5e-05 Smith-Waterman score: 219; 27.1% identity (57.2% similar) in 236 aa overlap (104-332:13-235) 80 90 100 110 120 130 pF1KB6 HQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAPFDRRATSLAWHPTHPSTVAVGSKG ::. . ..::. . .:.:. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDD 10 20 30 40 140 150 160 170 180 190 pF1KB6 GDIMLWNFGIKDKPTFIKGI-GAGGSITGLKFNPLNTNQFYASSMEGTTRLQDFKG-NIL . ::.. .::. : .. : . . ....: . . :.:. :. :. :... .:: XP_016 CRVNLWSI---NKPNCIMSLTGHTSPVESVRLNT-PEELIVAGSQSGSIRVWDLEAAKIL 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 RVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKE-LWNLRMHKKKVTHVAL :.. . . :: :::: ...:..:.. :. : .. : .. : :.. : . . XP_016 RTLMGHKA-NI--CSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 100 110 120 130 140 150 260 270 280 290 300 pF1KB6 NPCCDWFLATASVDQTVKIWDLRQVRGKASFLYSLP-HRHPVNAACFSPDGARLLTTDQK .: : ::.:. :.:::.::: :: .. .: : :::.. : :. : . .. XP_016 SPDGKW-LASAADDHTVKLWDLTA--GK--MMSEFPGHTGPVNVVEFHPNEYLLASGSSD 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 SEIRVYSASQWD---CPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTP :: .. ... : : : : : XP_016 RTIRFWDLEKFQVVSCIEGE-PGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVL 220 230 240 250 260 427 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:44:02 2016 done: Sat Nov 5 11:44:03 2016 Total Scan time: 9.070 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]