FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6681, 427 aa 1>>>pF1KB6681 427 - 427 aa - 427 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9433+/-0.00154; mu= -4.6421+/- 0.090 mean_var=248.3819+/-51.697, 0's: 0 Z-trim(104.6): 51 B-trim: 58 in 1/50 Lambda= 0.081379 statistics sampled from 7950 (7972) to 7950 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.245), width: 16 Scan time: 2.900 The best scores are: opt bits E(32554) CCDS4688.1 FLOT1 gene_id:10211|Hs108|chr6 ( 427) 2658 325.9 4.7e-89 CCDS11245.2 FLOT2 gene_id:2319|Hs108|chr17 ( 428) 1240 159.4 6.2e-39 CCDS82097.1 FLOT2 gene_id:2319|Hs108|chr17 ( 428) 1240 159.4 6.2e-39 >>CCDS4688.1 FLOT1 gene_id:10211|Hs108|chr6 (427 aa) initn: 2658 init1: 2658 opt: 2658 Z-score: 1712.2 bits: 325.9 E(32554): 4.7e-89 Smith-Waterman score: 2658; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB6 MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 YKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 AEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 AEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 QVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 EKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 LPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVN 370 380 390 400 410 420 pF1KB6 HKPLRTA ::::::: CCDS46 HKPLRTA >>CCDS11245.2 FLOT2 gene_id:2319|Hs108|chr17 (428 aa) initn: 1406 init1: 987 opt: 1240 Z-score: 812.5 bits: 159.4 E(32554): 6.2e-39 Smith-Waterman score: 1240; 48.1% identity (80.4% similar) in 418 aa overlap (4-419:6-417) 10 20 30 40 50 pF1KB6 MFFTCGPNEAMVVSGFCRSPPV--MVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVY : :::::.:::: : . .: :: ... ::.. :::::. .::. . : : CCDS11 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMT : .:: ..:::.:::::. . ::.::.::..::::. .: ...:.::::: :.:.. .: CCDS11 TAEGVALTVTGVAQVKIMTE-KELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLT 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 VEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDA ::.::.::..:.. : .::. :. ::: ..:.:.::..: ::: ::::..:: ::.:: CCDS11 VEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 RIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADL :: :::.::::::::. :.: ........ ..: ..: .::.:.:.. ::: . :.:.: CCDS11 DIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 AYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLER ::.:: :. .:.:........::.: .:.::. ::: : .::: : ::.::::: ..... CCDS11 AYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQ 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 LAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDM .::.:: . .. :.::: ..: ::::: .: : ..::::.: ::::.: : .::.. . CCDS11 IAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMAL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 LLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSI .:: :::.: .:..:::....: .: ::... :::.:: .:..:: ::. ::::.. CCDS11 VLEALPQIAAKIAAPLTKVDEI-VVLSGDNS----KVTSEVNRLLAELPASVHALTGVDL 360 370 380 390 400 410 420 pF1KB6 SQVNHKPLRTA :.. CCDS11 SKIPLIKKATGVQV 420 >>CCDS82097.1 FLOT2 gene_id:2319|Hs108|chr17 (428 aa) initn: 1406 init1: 987 opt: 1240 Z-score: 812.5 bits: 159.4 E(32554): 6.2e-39 Smith-Waterman score: 1240; 47.6% identity (80.6% similar) in 418 aa overlap (4-419:6-417) 10 20 30 40 50 pF1KB6 MFFTCGPNEAMVVSGFCRSPPV--MVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVY : :::::.:::: : . .: :: ... ::.. ::.::...:. . :.. CCDS82 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRLSLEVMTILCRCENIE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMT : .:::. :::.:::::. . ::.::.::..::::. .: ...:.::::: :.:.. .: CCDS82 TSEGVPLFVTGVAQVKIMTE-KELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLT 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 VEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDA ::.::.::..:.. : .::. :. ::: ..:.:.::..: ::: ::::..:: ::.:: CCDS82 VEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 RIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADL :: :::.::::::::. :.: ........ ..: ..: .::.:.:.. ::: . :.:.: CCDS82 DIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 AYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLER ::.:: :. .:.:........::.: .:.::. ::: : .::: : ::.::::: ..... CCDS82 AYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQ 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 LAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDM .::.:: . .. :.::: ..: ::::: .: : ..::::.: ::::.: : .::.. . CCDS82 IAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMAL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB6 LLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSI .:: :::.: .:..:::....: .: ::... :::.:: .:..:: ::. ::::.. CCDS82 VLEALPQIAAKIAAPLTKVDEI-VVLSGDNS----KVTSEVNRLLAELPASVHALTGVDL 360 370 380 390 400 410 420 pF1KB6 SQVNHKPLRTA :.. CCDS82 SKIPLIKKATGVQV 420 427 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:45:19 2016 done: Sat Nov 5 11:45:19 2016 Total Scan time: 2.900 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]