FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6687, 427 aa 1>>>pF1KB6687 427 - 427 aa - 427 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0617+/-0.00111; mu= -7.2753+/- 0.064 mean_var=313.8272+/-70.092, 0's: 0 Z-trim(109.6): 562 B-trim: 0 in 0/54 Lambda= 0.072398 statistics sampled from 10295 (11005) to 10295 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.338), width: 16 Scan time: 3.000 The best scores are: opt bits E(32554) CCDS7223.1 MAPK8 gene_id:5599|Hs108|chr10 ( 427) 2855 312.5 5.1e-85 CCDS7224.1 MAPK8 gene_id:5599|Hs108|chr10 ( 427) 2807 307.5 1.7e-83 CCDS3612.1 MAPK10 gene_id:5602|Hs108|chr4 ( 426) 2590 284.8 1.1e-76 CCDS34026.1 MAPK10 gene_id:5602|Hs108|chr4 ( 464) 2590 284.8 1.2e-76 CCDS7226.1 MAPK8 gene_id:5599|Hs108|chr10 ( 384) 2544 279.9 2.9e-75 CCDS7225.1 MAPK8 gene_id:5599|Hs108|chr10 ( 384) 2496 274.9 9.2e-74 CCDS43247.1 MAPK10 gene_id:5602|Hs108|chr4 ( 422) 2365 261.3 1.3e-69 CCDS4453.1 MAPK9 gene_id:5601|Hs108|chr5 ( 424) 2363 261.1 1.5e-69 CCDS4454.1 MAPK9 gene_id:5601|Hs108|chr5 ( 424) 2341 258.8 7.4e-69 CCDS43409.1 MAPK9 gene_id:5601|Hs108|chr5 ( 382) 2190 243.0 3.8e-64 CCDS43410.1 MAPK9 gene_id:5601|Hs108|chr5 ( 382) 2168 240.7 1.9e-63 CCDS82937.1 MAPK10 gene_id:5602|Hs108|chr4 ( 319) 1966 219.5 3.7e-57 CCDS47356.1 MAPK9 gene_id:5601|Hs108|chr5 ( 242) 1372 157.3 1.4e-38 CCDS60527.1 MAPK8 gene_id:5599|Hs108|chr10 ( 308) 1355 155.7 5.9e-38 CCDS78103.1 MAPK9 gene_id:5601|Hs108|chr5 ( 214) 1232 142.7 3.3e-34 CCDS14090.1 MAPK11 gene_id:5600|Hs108|chr22 ( 364) 954 113.8 2.7e-25 CCDS4816.1 MAPK14 gene_id:1432|Hs108|chr6 ( 360) 944 112.8 5.5e-25 CCDS4815.1 MAPK14 gene_id:1432|Hs108|chr6 ( 360) 928 111.1 1.8e-24 CCDS4817.1 MAPK14 gene_id:1432|Hs108|chr6 ( 307) 921 110.3 2.6e-24 CCDS4818.1 MAPK13 gene_id:5603|Hs108|chr6 ( 365) 920 110.3 3.2e-24 CCDS14089.1 MAPK12 gene_id:6300|Hs108|chr22 ( 367) 903 108.5 1.1e-23 CCDS13795.1 MAPK1 gene_id:5594|Hs108|chr22 ( 360) 869 105.0 1.3e-22 CCDS10672.1 MAPK3 gene_id:5595|Hs108|chr16 ( 379) 856 103.6 3.4e-22 CCDS42149.1 MAPK3 gene_id:5595|Hs108|chr16 ( 357) 835 101.4 1.5e-21 CCDS11206.1 MAPK7 gene_id:5598|Hs108|chr17 ( 816) 808 98.9 1.9e-20 CCDS6409.2 MAPK15 gene_id:225689|Hs108|chr8 ( 544) 694 86.9 5.4e-17 CCDS11224.2 NLK gene_id:51701|Hs108|chr17 ( 527) 693 86.7 5.7e-17 CCDS42148.1 MAPK3 gene_id:5595|Hs108|chr16 ( 335) 671 84.3 2e-16 CCDS11207.1 MAPK7 gene_id:5598|Hs108|chr17 ( 677) 628 80.0 7.6e-15 CCDS42437.1 MAPK4 gene_id:5596|Hs108|chr18 ( 587) 567 73.6 5.6e-13 CCDS10147.1 MAPK6 gene_id:5597|Hs108|chr15 ( 721) 562 73.2 9.4e-13 CCDS8898.1 CDK2 gene_id:1017|Hs108|chr12 ( 298) 509 67.3 2.3e-11 CCDS11736.1 CDK3 gene_id:1018|Hs108|chr17 ( 305) 489 65.2 9.9e-11 >>CCDS7223.1 MAPK8 gene_id:5599|Hs108|chr10 (427 aa) initn: 2855 init1: 2855 opt: 2855 Z-score: 1639.8 bits: 312.5 E(32554): 5.1e-85 Smith-Waterman score: 2855; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA 370 380 390 400 410 420 pF1KB6 GPLGCCR ::::::: CCDS72 GPLGCCR >>CCDS7224.1 MAPK8 gene_id:5599|Hs108|chr10 (427 aa) initn: 2807 init1: 2807 opt: 2807 Z-score: 1612.7 bits: 307.5 E(32554): 1.7e-83 Smith-Waterman score: 2807; 98.1% identity (99.1% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ :::::::::::::::::::::::::::.::::::::::. .:::: :.:::::::::: CCDS72 MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA 370 380 390 400 410 420 pF1KB6 GPLGCCR ::::::: CCDS72 GPLGCCR >>CCDS3612.1 MAPK10 gene_id:5602|Hs108|chr4 (426 aa) initn: 2403 init1: 2403 opt: 2590 Z-score: 1490.2 bits: 284.8 E(32554): 1.1e-76 Smith-Waterman score: 2590; 89.7% identity (96.0% similar) in 427 aa overlap (1-427:1-426) 10 20 30 40 50 60 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP ::.:: ::.:::::.:::::::::::::::::::::::::::::::.:.::::::::::: CCDS36 MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ ::::::::::::::::::::::::::.:::::::::.::::::::.:::::::::::::: CCDS36 FQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ ::::::::::::::::::::::::::::::::::::::.. .:::: :.:::::::::: CCDS36 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK :::::::::::::::::.:::::::::: .: ::::: :::::::::::::::::::::: CCDS36 LGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV ::::: .::::::.:::::::::::::.:.:::::.: :::::::::::::::::::::: CCDS36 MLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA :. ::.:::::..::::: :::: :.:. ::::::.:::::: ::::::::::::.: CCDS36 MNSEEKTKNGVVKGQPSPSGAAV-NSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASA 370 380 390 400 410 pF1KB6 GPLGCCR ::::::: CCDS36 GPLGCCR 420 >>CCDS34026.1 MAPK10 gene_id:5602|Hs108|chr4 (464 aa) initn: 2403 init1: 2403 opt: 2590 Z-score: 1489.7 bits: 284.8 E(32554): 1.2e-76 Smith-Waterman score: 2590; 89.7% identity (96.0% similar) in 427 aa overlap (1-427:39-464) 10 20 30 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLK ::.:: ::.:::::.::::::::::::::: CCDS34 CSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 PIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLN ::::::::::::::::.:.:::::::::::::::::::::::::::::::::::::.::: CCDS34 PIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 VFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHR ::::::.::::::::.:::::::::::::::::::::::::::::::::::::::::::: CCDS34 VFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 DLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 VGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYS ::::::::.. .:::: :.:::::::::::::::::::::::::::.:::::::::: . CCDS34 VGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLT 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 FEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEA : ::::: ::::::::::::::::::::::::::: .::::::.:::::::::::::.:. CCDS34 FPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEV 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 EAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHP :::::.: :::::::::::::::::::::::. ::.:::::..::::: :::: :.:. CCDS34 EAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAV-NSSESL 370 380 390 400 410 420 400 410 420 pF1KB6 SSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR ::::::.:::::: ::::::::::::.:::::::: CCDS34 PPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR 430 440 450 460 >>CCDS7226.1 MAPK8 gene_id:5599|Hs108|chr10 (384 aa) initn: 2544 init1: 2544 opt: 2544 Z-score: 1464.8 bits: 279.9 E(32554): 2.9e-75 Smith-Waterman score: 2544; 100.0% identity (100.0% similar) in 379 aa overlap (1-379:1-379) 10 20 30 40 50 60 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA ::::::::::::::::::: CCDS72 MDLEERTKNGVIRGQPSPLAQVQQ 370 380 >>CCDS7225.1 MAPK8 gene_id:5599|Hs108|chr10 (384 aa) initn: 2496 init1: 2496 opt: 2496 Z-score: 1437.7 bits: 274.9 E(32554): 9.2e-74 Smith-Waterman score: 2496; 97.9% identity (98.9% similar) in 379 aa overlap (1-379:1-379) 10 20 30 40 50 60 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ :::::::::::::::::::::::::::.::::::::::. .:::: :.:::::::::: CCDS72 MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA ::::::::::::::::::: CCDS72 MDLEERTKNGVIRGQPSPLAQVQQ 370 380 >>CCDS43247.1 MAPK10 gene_id:5602|Hs108|chr4 (422 aa) initn: 2365 init1: 2365 opt: 2365 Z-score: 1363.2 bits: 261.3 E(32554): 1.3e-69 Smith-Waterman score: 2365; 91.3% identity (97.4% similar) in 378 aa overlap (1-378:39-416) 10 20 30 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLK ::.:: ::.:::::.::::::::::::::: CCDS43 CSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 PIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLN ::::::::::::::::.:.:::::::::::::::::::::::::::::::::::::.::: CCDS43 PIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 VFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHR ::::::.::::::::.:::::::::::::::::::::::::::::::::::::::::::: CCDS43 VFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB6 DLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB6 VGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYS ::::::::.. .:::: :.:::::::::::::::::::::::::::.:::::::::: . CCDS43 VGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLT 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB6 FEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEA : ::::: ::::::::::::::::::::::::::: .::::::.:::::::::::::.:. CCDS43 FPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEV 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB6 EAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHP :::::.: :::::::::::::::::::::::. ::.:::::..::::: CCDS43 EAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSAQVQQ 370 380 390 400 410 420 400 410 420 pF1KB6 SSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR >>CCDS4453.1 MAPK9 gene_id:5601|Hs108|chr5 (424 aa) initn: 2366 init1: 2190 opt: 2363 Z-score: 1362.1 bits: 261.1 E(32554): 1.5e-69 Smith-Waterman score: 2363; 82.0% identity (93.9% similar) in 427 aa overlap (1-427:1-424) 10 20 30 40 50 60 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP :: :: :..::::...:::::::::::.:::::::::::::::.:..: :::.:::::: CCDS44 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ ::::::::::::::::.:::::::::.:::::::::.::::::::.:::::::::::::. CCDS44 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.: CCDS44 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ :::::::::::::::::::::::::::::::::::::..:: :.: :::::::::::::: CCDS44 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK :::: :::::::::::.:::::::: : .::.:::: .::..::..:.:.::::::::: CCDS44 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV ::::: .:::::::::.::::.:::::.:::::::.: : ::.::::.:::::::::::: CCDS44 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA :: :::.::::.. ::: :..... ::.:::.::.:::::. ::::::::::.:.. CCDS44 MDWEERSKNGVVKDQPSD---AAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDAST 370 380 390 400 410 pF1KB6 GPLGCCR ::: :: CCDS44 GPLEGCR 420 >>CCDS4454.1 MAPK9 gene_id:5601|Hs108|chr5 (424 aa) initn: 2344 init1: 2168 opt: 2341 Z-score: 1349.7 bits: 258.8 E(32554): 7.4e-69 Smith-Waterman score: 2341; 81.5% identity (93.4% similar) in 427 aa overlap (1-427:1-424) 10 20 30 40 50 60 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP :: :: :..::::...:::::::::::.:::::::::::::::.:..: :::.:::::: CCDS44 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ ::::::::::::::::.:::::::::.:::::::::.::::::::.:::::::::::::. CCDS44 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.: CCDS44 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ :::::::::::::::::::::::::::::::::::.::. ::::: :.:::::::::: CCDS44 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK :::: :::::::::::.:::::::: : .::.:::: .::..::..:.:.::::::::: CCDS44 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV ::::: .:::::::::.::::.:::::.:::::::.: : ::.::::.:::::::::::: CCDS44 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA :: :::.::::.. ::: :..... ::.:::.::.:::::. ::::::::::.:.. CCDS44 MDWEERSKNGVVKDQPSD---AAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDAST 370 380 390 400 410 pF1KB6 GPLGCCR ::: :: CCDS44 GPLEGCR 420 >>CCDS43409.1 MAPK9 gene_id:5601|Hs108|chr5 (382 aa) initn: 2190 init1: 2190 opt: 2190 Z-score: 1265.0 bits: 243.0 E(32554): 3.8e-64 Smith-Waterman score: 2190; 85.1% identity (95.5% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB6 MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP :: :: :..::::...:::::::::::.:::::::::::::::.:..: :::.:::::: CCDS43 MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ ::::::::::::::::.:::::::::.:::::::::.::::::::.:::::::::::::. CCDS43 FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.: CCDS43 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ :::::::::::::::::::::::::::::::::::::..:: :.: :::::::::::::: CCDS43 MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK :::: :::::::::::.:::::::: : .::.:::: .::..::..:.:.::::::::: CCDS43 LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV ::::: .:::::::::.::::.:::::.:::::::.: : ::.::::.:::::::::::: CCDS43 MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAA :: :::.::::.. ::: CCDS43 MDWEERSKNGVVKDQPSAQMQQ 370 380 427 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:47:10 2016 done: Sat Nov 5 11:47:11 2016 Total Scan time: 3.000 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]