FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6689, 335 aa 1>>>pF1KB6689 335 - 335 aa - 335 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5161+/-0.000428; mu= 3.8962+/- 0.026 mean_var=161.2819+/-33.699, 0's: 0 Z-trim(114.4): 200 B-trim: 493 in 1/57 Lambda= 0.100991 statistics sampled from 23837 (24174) to 23837 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.283), width: 16 Scan time: 7.940 The best scores are: opt bits E(85289) NP_001123486 (OMIM: 176394) pregnancy-specific bet ( 335) 2254 340.9 2.3e-93 NP_002772 (OMIM: 176394) pregnancy-specific beta-1 ( 335) 2254 340.9 2.3e-93 XP_016882492 (OMIM: 176394) PREDICTED: pregnancy-s ( 335) 2254 340.9 2.3e-93 NP_001263424 (OMIM: 176393) pregnancy-specific bet ( 326) 1898 289.0 9.2e-78 XP_016882490 (OMIM: 176393) PREDICTED: pregnancy-s ( 333) 1898 289.0 9.4e-78 NP_001317453 (OMIM: 176390) pregnancy-specific bet ( 326) 1856 282.9 6.4e-76 XP_005259122 (OMIM: 176390) PREDICTED: pregnancy-s ( 333) 1856 282.9 6.5e-76 NP_001288636 (OMIM: 176398) pregnancy-specific bet ( 333) 1853 282.5 8.8e-76 XP_016882494 (OMIM: 176398) PREDICTED: pregnancy-s ( 402) 1843 281.1 2.8e-75 XP_016882487 (OMIM: 176393) PREDICTED: pregnancy-s ( 349) 1766 269.8 6e-72 XP_011525428 (OMIM: 176392) PREDICTED: pregnancy-s ( 357) 1724 263.7 4.2e-70 NP_112536 (OMIM: 176391) pregnancy-specific beta-1 ( 335) 1713 262.1 1.2e-69 NP_002776 (OMIM: 176401) pregnancy-specific beta-1 ( 335) 1651 253.0 6.4e-67 NP_998798 (OMIM: 176393) pregnancy-specific beta-1 ( 326) 1631 250.1 4.7e-66 XP_016882491 (OMIM: 176393) PREDICTED: pregnancy-s ( 333) 1631 250.1 4.8e-66 XP_011525288 (OMIM: 176397) PREDICTED: pregnancy-s ( 326) 1613 247.5 2.9e-65 NP_001288637 (OMIM: 176398) pregnancy-specific bet ( 333) 1607 246.6 5.4e-65 XP_005259132 (OMIM: 176398) PREDICTED: pregnancy-s ( 402) 1597 245.2 1.7e-64 XP_011525427 (OMIM: 176390) PREDICTED: pregnancy-s ( 333) 1584 243.3 5.6e-64 XP_016882489 (OMIM: 176393) PREDICTED: pregnancy-s ( 342) 1499 230.9 3e-60 XP_016882488 (OMIM: 176393) PREDICTED: pregnancy-s ( 349) 1499 230.9 3.1e-60 XP_016881685 (OMIM: 615747) PREDICTED: carcinoembr ( 331) 1272 197.8 2.7e-50 XP_016881683 (OMIM: 615747) PREDICTED: carcinoembr ( 368) 1265 196.8 5.9e-50 XP_011524642 (OMIM: 615747) PREDICTED: carcinoembr ( 415) 1265 196.9 6.4e-50 XP_016881684 (OMIM: 615747) PREDICTED: carcinoembr ( 349) 1260 196.1 9.3e-50 NP_001807 (OMIM: 615747) carcinoembryonic antigen- ( 349) 1260 196.1 9.3e-50 NP_002474 (OMIM: 163980) carcinoembryonic antigen- ( 344) 1234 192.3 1.3e-48 XP_011525292 (OMIM: 163980) PREDICTED: carcinoembr ( 324) 1228 191.4 2.2e-48 NP_001171744 (OMIM: 109770) carcinoembryonic antig ( 461) 1217 189.9 8.9e-48 NP_066296 (OMIM: 176392) pregnancy-specific beta-1 ( 428) 1212 189.2 1.4e-47 XP_011525508 (OMIM: 109770) PREDICTED: carcinoembr ( 351) 1207 188.4 2e-47 NP_002774 (OMIM: 176396) putative pregnancy-specif ( 419) 1207 188.4 2.3e-47 NP_001171745 (OMIM: 109770) carcinoembryonic antig ( 368) 1206 188.2 2.3e-47 NP_001020083 (OMIM: 109770) carcinoembryonic antig ( 464) 1207 188.5 2.4e-47 NP_001192273 (OMIM: 109770) carcinoembryonic antig ( 468) 1207 188.5 2.5e-47 NP_001171742 (OMIM: 109770) carcinoembryonic antig ( 430) 1206 188.3 2.6e-47 NP_001703 (OMIM: 109770) carcinoembryonic antigen- ( 526) 1207 188.5 2.7e-47 NP_001123639 (OMIM: 176397) pregnancy-specific bet ( 419) 1185 185.2 2.1e-46 NP_874366 (OMIM: 176397) pregnancy-specific beta-1 ( 426) 1185 185.2 2.1e-46 NP_001171755 (OMIM: 176390) pregnancy-specific bet ( 417) 1183 184.9 2.5e-46 NP_001171754 (OMIM: 176390) pregnancy-specific bet ( 419) 1183 184.9 2.6e-46 NP_008836 (OMIM: 176390) pregnancy-specific beta-1 ( 426) 1183 184.9 2.6e-46 NP_001284702 (OMIM: 176390) pregnancy-specific bet ( 428) 1183 184.9 2.6e-46 XP_011525429 (OMIM: 176392) PREDICTED: pregnancy-s ( 272) 1160 181.4 1.9e-45 NP_002771 (OMIM: 176393) pregnancy-specific beta-1 ( 419) 1163 182.0 1.9e-45 XP_016882486 (OMIM: 176393) PREDICTED: pregnancy-s ( 426) 1163 182.0 2e-45 XP_011524624 (OMIM: 114890) PREDICTED: carcinoembr ( 524) 1154 180.8 5.7e-45 NP_002775 (OMIM: 176398) pregnancy-specific beta-1 ( 426) 1151 180.3 6.6e-45 XP_016882496 (OMIM: 176398) PREDICTED: pregnancy-s ( 436) 1151 180.3 6.7e-45 XP_016882493 (OMIM: 176398) PREDICTED: pregnancy-s ( 495) 1151 180.3 7.4e-45 >>NP_001123486 (OMIM: 176394) pregnancy-specific beta-1- (335 aa) initn: 2254 init1: 2254 opt: 2254 Z-score: 1797.2 bits: 340.9 E(85289): 2.3e-93 Smith-Waterman score: 2254; 99.4% identity (100.0% similar) in 335 aa overlap (1-335:1-335) 10 20 30 40 50 60 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_001 MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPD ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT 250 260 270 280 290 300 310 320 330 pF1KB6 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI ::::::::::::::::::::::::::::::::::: NP_001 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI 310 320 330 >>NP_002772 (OMIM: 176394) pregnancy-specific beta-1-gly (335 aa) initn: 2254 init1: 2254 opt: 2254 Z-score: 1797.2 bits: 340.9 E(85289): 2.3e-93 Smith-Waterman score: 2254; 99.4% identity (100.0% similar) in 335 aa overlap (1-335:1-335) 10 20 30 40 50 60 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_002 MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPD ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_002 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT 250 260 270 280 290 300 310 320 330 pF1KB6 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI ::::::::::::::::::::::::::::::::::: NP_002 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI 310 320 330 >>XP_016882492 (OMIM: 176394) PREDICTED: pregnancy-speci (335 aa) initn: 2254 init1: 2254 opt: 2254 Z-score: 1797.2 bits: 340.9 E(85289): 2.3e-93 Smith-Waterman score: 2254; 99.4% identity (100.0% similar) in 335 aa overlap (1-335:1-335) 10 20 30 40 50 60 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: XP_016 MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPD ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT 250 260 270 280 290 300 310 320 330 pF1KB6 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI ::::::::::::::::::::::::::::::::::: XP_016 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI 310 320 330 >>NP_001263424 (OMIM: 176393) pregnancy-specific beta-1- (326 aa) initn: 1898 init1: 1898 opt: 1898 Z-score: 1517.0 bits: 289.0 E(85289): 9.2e-78 Smith-Waterman score: 1898; 88.5% identity (94.1% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ :::::::::::.::::::::::::::::: : :::::::: ::::::::::::::::::: NP_001 MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY :::::::::::. ::::::::::::: ::::::.::: :::::::::::::.:::::: NP_001 NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW ::::::: : : ::::.:::.:. :: :::::::: .::::::::.:::::::.:::::: NP_001 TLHIIKRRDGTGGVTGHFTFTLHPKLSKPYITINNLNPRENKDVLTFTCEPKSKNYTYIW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPD :::::::::::::::::::::::::.:::::::::.:::::: ::..::::::::::::: NP_001 WLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT ::::::::::::::::::::::::::: :.: :::::::: :::::::::::::: :::. NP_001 LPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQKLSIPQITTKHSGLYA 250 260 270 280 290 300 310 320 330 pF1KB6 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI :::::::::::::::.::.:: NP_001 CSVRNSATGKESSKSITVKVSDWILP 310 320 >>XP_016882490 (OMIM: 176393) PREDICTED: pregnancy-speci (333 aa) initn: 1898 init1: 1898 opt: 1898 Z-score: 1516.9 bits: 289.0 E(85289): 9.4e-78 Smith-Waterman score: 1898; 88.5% identity (94.1% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ :::::::::::.::::::::::::::::: : :::::::: ::::::::::::::::::: XP_016 MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY :::::::::::. ::::::::::::: ::::::.::: :::::::::::::.:::::: XP_016 NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW ::::::: : : ::::.:::.:. :: :::::::: .::::::::.:::::::.:::::: XP_016 TLHIIKRRDGTGGVTGHFTFTLHPKLSKPYITINNLNPRENKDVLTFTCEPKSKNYTYIW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPD :::::::::::::::::::::::::.:::::::::.:::::: ::..::::::::::::: XP_016 WLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT ::::::::::::::::::::::::::: :.: :::::::: :::::::::::::: :::. XP_016 LPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQKLSIPQITTKHSGLYA 250 260 270 280 290 300 310 320 330 pF1KB6 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI :::::::::::::::.::.:: XP_016 CSVRNSATGKESSKSITVKVSGKWIPASLAIGI 310 320 330 >>NP_001317453 (OMIM: 176390) pregnancy-specific beta-1- (326 aa) initn: 1856 init1: 1856 opt: 1856 Z-score: 1484.0 bits: 282.9 E(85289): 6.4e-76 Smith-Waterman score: 1856; 86.9% identity (92.2% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ :: ::::::::.: :::.::::::::::::: :::::::: : ::::::::::::::::: NP_001 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY ::.::::::::. :::::::::::::.: ::::::.::::.::::::::::::::::::: NP_001 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW :::::: : :::::: :::.:. ::::::::::: .:::::::: :::::::::::::: NP_001 TLHIIKGDDGTRGVTGRFTFTLHPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPD :::::::::::::::::::::::::::::::::::.:::::: ::..::::::::::::: NP_001 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT :: :::::::::::: ::::: :.:::::.: :::: ::: :::: : .::::: :::. NP_001 LPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQKLFIRHITTKHSGLYV 250 260 270 280 290 300 310 320 330 pF1KB6 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI ::::::::::::::::::::: NP_001 CSVRNSATGKESSKSMTVEVSDWTVP 310 320 >>XP_005259122 (OMIM: 176390) PREDICTED: pregnancy-speci (333 aa) initn: 1856 init1: 1856 opt: 1856 Z-score: 1483.8 bits: 282.9 E(85289): 6.5e-76 Smith-Waterman score: 1856; 86.9% identity (92.2% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ :: ::::::::.: :::.::::::::::::: :::::::: : ::::::::::::::::: XP_005 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY ::.::::::::. :::::::::::::.: ::::::.::::.::::::::::::::::::: XP_005 NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW :::::: : :::::: :::.:. ::::::::::: .:::::::: :::::::::::::: XP_005 TLHIIKGDDGTRGVTGRFTFTLHPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPD :::::::::::::::::::::::::::::::::::.:::::: ::..::::::::::::: XP_005 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT :: :::::::::::: ::::: :.:::::.: :::: ::: :::: : .::::: :::. XP_005 LPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQKLFIRHITTKHSGLYV 250 260 270 280 290 300 310 320 330 pF1KB6 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI ::::::::::::::::::::: XP_005 CSVRNSATGKESSKSMTVEVSGKWIPASLAIGF 310 320 330 >>NP_001288636 (OMIM: 176398) pregnancy-specific beta-1- (333 aa) initn: 1931 init1: 1853 opt: 1853 Z-score: 1481.5 bits: 282.5 E(85289): 8.8e-76 Smith-Waterman score: 1853; 84.5% identity (92.3% similar) in 323 aa overlap (1-323:1-323) 10 20 30 40 50 60 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ :::: :: :::.:::::.::::::::::: : ::.::::: ::::::::::::::::::: NP_001 MGPLPAPSCTQRITWKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY :: ::.::::.. :::::: ::.:::.: ::::::.::::::::::::::::::.:::.: NP_001 NLPGYFWYKGEMTDLYHYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW :::::::::.:: .:::.:: ::: ::::::: .::::::::::::::::::::::: NP_001 TLHIIKRGDETREEIRHFTFTLYSKLPIPYITINNLNPRENKDVLAFTCEPKSENYTYIW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPD ::::::::::: :::::::::::::::::::::::.:::::: ::..:.:: :::::::: NP_001 WLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNVLYGPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT :: :::::::::::::: ::::.::::::::::::::::::::::: ::::: .: :::. NP_001 LPRIYPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQKLFIPQITRNHSGLYA 250 260 270 280 290 300 310 320 330 pF1KB6 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI :::.::::::: ::::::.::.: NP_001 CSVHNSATGKEISKSMTVKVSGPCHGDLTESQS 310 320 330 >>XP_016882494 (OMIM: 176398) PREDICTED: pregnancy-speci (402 aa) initn: 1843 init1: 1843 opt: 1843 Z-score: 1472.5 bits: 281.1 E(85289): 2.8e-75 Smith-Waterman score: 1843; 84.7% identity (92.2% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ :::: :: :::.:::::.::::::::::: : ::.::::: ::::::::::::::::::: XP_016 MGPLPAPSCTQRITWKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY :: ::.::::.. :::::: ::.:::.: ::::::.::::::::::::::::::.:::.: XP_016 NLPGYFWYKGEMTDLYHYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW :::::::::.:: .:::.:: ::: ::::::: .::::::::::::::::::::::: XP_016 TLHIIKRGDETREEIRHFTFTLYSKLPIPYITINNLNPRENKDVLAFTCEPKSENYTYIW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPD ::::::::::: :::::::::::::::::::::::.:::::: ::..:.:: :::::::: XP_016 WLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNVLYGPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT :: :::::::::::::: ::::.::::::::::::::::::::::: ::::: .: :::. XP_016 LPRIYPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQKLFIPQITRNHSGLYA 250 260 270 280 290 300 310 320 330 pF1KB6 CSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI :::.::::::: ::::::.:: XP_016 CSVHNSATGKEISKSMTVKVSGKWIPASLAVGFYVESIWLSEKSQENIFIPSLCPMGTSK 310 320 330 340 350 360 >>XP_016882487 (OMIM: 176393) PREDICTED: pregnancy-speci (349 aa) initn: 1754 init1: 1754 opt: 1766 Z-score: 1412.7 bits: 269.8 E(85289): 6e-72 Smith-Waterman score: 1766; 84.0% identity (91.2% similar) in 319 aa overlap (3-321:19-337) 10 20 30 40 pF1KB6 MGPLSAPPCTQHITWKGVLLTASLLNFWNLPITAQVTIEALPPK : .. : ..:: . . :::::::: : :::::::: ::: XP_016 MKHCPQQETSTIGGKKKHPEGGDPENSHIYRSLPPVPASLLNFWNPPTTAQVTIEAQPPK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 VSEGKDVLLLVHNLPQNLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSN :::::::::::::::::::::::::::. ::::::::::::: ::::::.::: :::: XP_016 VSEGKDVLLLVHNLPQNLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSN 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 ASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDV :::::::::.::::::::::::: : : ::::.:::.:. :: :::::::: .::::::: XP_016 ASLLIQNVTQEDAGSYTLHIIKRRDGTGGVTGHFTFTLHPKLSKPYITINNLNPRENKDV 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 LAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDG :.:::::::.:::::::::::::::::::::::::::::::.:::::::::.:::::: : XP_016 LTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQCEIRDRYG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 GMHSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQ :..:::::::::::::::::::::::::::::::::::::::: :.: :::::::: ::: XP_016 GIRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQ 250 260 270 280 290 300 290 300 310 320 330 pF1KB6 KLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI ::::::::::: :::.:::::::::::::::.::.:: XP_016 KLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVSGKWIPASLAIGI 310 320 330 340 335 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:14:22 2016 done: Sat Nov 5 18:14:23 2016 Total Scan time: 7.940 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]