FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6695, 429 aa 1>>>pF1KB6695 429 - 429 aa - 429 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9277+/-0.00031; mu= 10.8219+/- 0.020 mean_var=114.8223+/-23.768, 0's: 0 Z-trim(118.6): 128 B-trim: 0 in 0/56 Lambda= 0.119691 statistics sampled from 31669 (31800) to 31669 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.373), width: 16 Scan time: 10.030 The best scores are: opt bits E(85289) XP_016885010 (OMIM: 300344) PREDICTED: melanoma-as ( 429) 2876 507.2 3.2e-143 NP_005357 (OMIM: 300344) melanoma-associated antig ( 429) 2876 507.2 3.2e-143 NP_001011544 (OMIM: 300344) melanoma-associated an ( 400) 2658 469.6 6.4e-132 XP_011529466 (OMIM: 300344) PREDICTED: melanoma-as ( 421) 2656 469.3 8.5e-132 XP_016885011 (OMIM: 300344) PREDICTED: melanoma-as ( 394) 2641 466.6 4.8e-131 XP_005274734 (OMIM: 300175) PREDICTED: melanoma-as ( 397) 1373 247.7 4e-65 NP_001011549 (OMIM: 300175) melanoma-associated an ( 317) 1243 225.2 1.9e-58 NP_002353 (OMIM: 300175) melanoma-associated antig ( 317) 1243 225.2 1.9e-58 XP_005274735 (OMIM: 300175) PREDICTED: melanoma-as ( 317) 1243 225.2 1.9e-58 XP_005274736 (OMIM: 300175) PREDICTED: melanoma-as ( 317) 1243 225.2 1.9e-58 NP_001011550 (OMIM: 300175) melanoma-associated an ( 317) 1243 225.2 1.9e-58 NP_001011548 (OMIM: 300175) melanoma-associated an ( 317) 1243 225.2 1.9e-58 NP_005355 (OMIM: 300341) melanoma-associated antig ( 318) 1214 220.2 6.1e-57 NP_001159872 (OMIM: 300341) melanoma-associated an ( 318) 1214 220.2 6.1e-57 XP_016885009 (OMIM: 300341) PREDICTED: melanoma-as ( 318) 1214 220.2 6.1e-57 NP_001159873 (OMIM: 300341) melanoma-associated an ( 318) 1214 220.2 6.1e-57 XP_011529463 (OMIM: 300174) PREDICTED: melanoma-as ( 314) 1191 216.2 9.4e-56 XP_006724881 (OMIM: 300174) PREDICTED: melanoma-as ( 314) 1191 216.2 9.4e-56 XP_005274733 (OMIM: 300174) PREDICTED: melanoma-as ( 314) 1191 216.2 9.4e-56 NP_005353 (OMIM: 300174) melanoma-associated antig ( 314) 1191 216.2 9.4e-56 XP_011529462 (OMIM: 300174) PREDICTED: melanoma-as ( 314) 1191 216.2 9.4e-56 NP_005354 (OMIM: 300176) melanoma-associated antig ( 314) 1188 215.7 1.4e-55 NP_787064 (OMIM: 300176) melanoma-associated antig ( 314) 1188 215.7 1.4e-55 XP_005278249 (OMIM: 300764) PREDICTED: melanoma-as ( 315) 1188 215.7 1.4e-55 NP_005356 (OMIM: 300342) melanoma-associated antig ( 315) 1188 215.7 1.4e-55 NP_001074259 (OMIM: 300764) melanoma-associated an ( 315) 1188 215.7 1.4e-55 XP_005278250 (OMIM: 300764) PREDICTED: melanoma-as ( 315) 1188 215.7 1.4e-55 XP_005262392 (OMIM: 300342) PREDICTED: melanoma-as ( 315) 1188 215.7 1.4e-55 XP_005262391 (OMIM: 300342) PREDICTED: melanoma-as ( 315) 1188 215.7 1.4e-55 NP_001159859 (OMIM: 300177) melanoma-associated an ( 314) 1173 213.1 8.1e-55 NP_001159858 (OMIM: 300177) melanoma-associated an ( 314) 1173 213.1 8.1e-55 NP_005358 (OMIM: 300177) melanoma-associated antig ( 314) 1173 213.1 8.1e-55 NP_001269433 (OMIM: 300173) melanoma-associated an ( 314) 1158 210.5 4.9e-54 NP_001308332 (OMIM: 300549) melanoma-associated an ( 314) 1158 210.5 4.9e-54 NP_001308333 (OMIM: 300549) melanoma-associated an ( 314) 1158 210.5 4.9e-54 XP_016885008 (OMIM: 300173) PREDICTED: melanoma-as ( 314) 1158 210.5 4.9e-54 NP_001269431 (OMIM: 300173) melanoma-associated an ( 314) 1158 210.5 4.9e-54 NP_705692 (OMIM: 300549) melanoma-associated antig ( 314) 1158 210.5 4.9e-54 NP_001308331 (OMIM: 300549) melanoma-associated an ( 314) 1158 210.5 4.9e-54 NP_005352 (OMIM: 300173) melanoma-associated antig ( 314) 1158 210.5 4.9e-54 NP_786884 (OMIM: 300173) melanoma-associated antig ( 314) 1158 210.5 4.9e-54 NP_786885 (OMIM: 300173) melanoma-associated antig ( 314) 1158 210.5 4.9e-54 XP_016884895 (OMIM: 300549) PREDICTED: melanoma-as ( 314) 1158 210.5 4.9e-54 NP_001269434 (OMIM: 300173) melanoma-associated an ( 314) 1158 210.5 4.9e-54 NP_001308330 (OMIM: 300549) melanoma-associated an ( 314) 1158 210.5 4.9e-54 NP_001308329 (OMIM: 300549) melanoma-associated an ( 314) 1158 210.5 4.9e-54 NP_001269430 (OMIM: 300173) melanoma-associated an ( 314) 1158 210.5 4.9e-54 NP_001238757 (OMIM: 300343) melanoma-associated an ( 369) 1079 196.9 7.2e-50 NP_001011543 (OMIM: 300343) melanoma-associated an ( 369) 1079 196.9 7.2e-50 NP_066386 (OMIM: 300343) melanoma-associated antig ( 369) 1079 196.9 7.2e-50 >>XP_016885010 (OMIM: 300344) PREDICTED: melanoma-associ (429 aa) initn: 2876 init1: 2876 opt: 2876 Z-score: 2692.4 bits: 507.2 E(85289): 3.2e-143 Smith-Waterman score: 2876; 100.0% identity (100.0% similar) in 429 aa overlap (1-429:1-429) 10 20 30 40 50 60 pF1KB6 METQFRRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 METQFRRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PRVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KPEEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPEEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SPTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 GLITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 GIQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 QNWVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNWVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYED 370 380 390 400 410 420 pF1KB6 ALREEGEGV ::::::::: XP_016 ALREEGEGV >>NP_005357 (OMIM: 300344) melanoma-associated antigen 1 (429 aa) initn: 2876 init1: 2876 opt: 2876 Z-score: 2692.4 bits: 507.2 E(85289): 3.2e-143 Smith-Waterman score: 2876; 100.0% identity (100.0% similar) in 429 aa overlap (1-429:1-429) 10 20 30 40 50 60 pF1KB6 METQFRRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 METQFRRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PRVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PRVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KPEEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KPEEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 SPTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SPTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 GLITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GLITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 GIQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GIQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB6 QNWVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QNWVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYED 370 380 390 400 410 420 pF1KB6 ALREEGEGV ::::::::: NP_005 ALREEGEGV >>NP_001011544 (OMIM: 300344) melanoma-associated antige (400 aa) initn: 2658 init1: 2658 opt: 2658 Z-score: 2489.4 bits: 469.6 E(85289): 6.4e-132 Smith-Waterman score: 2658; 99.7% identity (100.0% similar) in 398 aa overlap (32-429:3-400) 10 20 30 40 50 60 pF1KB6 ETQFRRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDLP .::::::::::::::::::::::::::::: NP_001 MSKVSTMFSEDDFQSTERAPYGPQLQWSQDLP 10 20 30 70 80 90 100 110 120 pF1KB6 RVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCK 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 PEEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESFS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 PTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 LITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDG 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 IQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQ 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB6 NWVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NWVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDA 340 350 360 370 380 390 pF1KB6 LREEGEGV :::::::: NP_001 LREEGEGV 400 >>XP_011529466 (OMIM: 300344) PREDICTED: melanoma-associ (421 aa) initn: 2656 init1: 2656 opt: 2656 Z-score: 2487.2 bits: 469.3 E(85289): 8.5e-132 Smith-Waterman score: 2656; 100.0% identity (100.0% similar) in 397 aa overlap (33-429:25-421) 10 20 30 40 50 60 pF1KB6 TQFRRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDLPR :::::::::::::::::::::::::::::: XP_011 MTGQQVEPHLISRGRSPRIFRTQGVSTMFSEDDFQSTERAPYGPQLQWSQDLPR 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 VQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQVFREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 EEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEGLQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESFSP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 TAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAMDAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 ITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITKAEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 QCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCNEQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQN 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB6 WVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WVQEKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDAL 360 370 380 390 400 410 pF1KB6 REEGEGV ::::::: XP_011 REEGEGV 420 >>XP_016885011 (OMIM: 300344) PREDICTED: melanoma-associ (394 aa) initn: 2641 init1: 2641 opt: 2641 Z-score: 2473.6 bits: 466.6 E(85289): 4.8e-131 Smith-Waterman score: 2641; 100.0% identity (100.0% similar) in 394 aa overlap (36-429:1-394) 10 20 30 40 50 60 pF1KB6 RRGGLGCSPASIKRKKKREDSGDFGLQVSTMFSEDDFQSTERAPYGPQLQWSQDLPRVQV :::::::::::::::::::::::::::::: XP_016 MFSEDDFQSTERAPYGPQLQWSQDLPRVQV 10 20 30 70 80 90 100 110 120 pF1KB6 FREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FREQANLEDRSPRRTQRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEG 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 LQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESFSPTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQAQEEDLGLVGAQALQAEEQEAAFFSSTLNVGTLEELPAAESPSPPQSPQEESFSPTAM 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 DAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAIFGSLSDEGSGSQEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 AEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEMLGSVIKNYEDYFPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCN 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 EQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQSMPKSGLLIIVLGVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQ 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB6 EKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKYLVYRQVPGTDPACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALREE 340 350 360 370 380 390 pF1KB6 GEGV :::: XP_016 GEGV >>XP_005274734 (OMIM: 300175) PREDICTED: melanoma-associ (397 aa) initn: 1210 init1: 873 opt: 1373 Z-score: 1290.2 bits: 247.7 E(85289): 4e-65 Smith-Waterman score: 1373; 60.2% identity (78.6% similar) in 369 aa overlap (62-429:32-397) 40 50 60 70 80 90 pF1KB6 QVSTMFSEDDFQSTERAPYGPQLQWSQDLPRVQVFREQANLEDRSPRRTQRITGGEQVLW : : .. .. ::: : : :: : . :: XP_005 PLTCALGVREKRAALTSRLGLAEGSGPGPVRSQGSEQTGQPEDRIPWRPQRSTKEKICLW 10 20 30 40 50 60 100 110 120 130 140 150 pF1KB6 GPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEGLQAQEEDLGLVGAQALQAEEQEAAFF ::.:..:.. :: :::::: ::.:::::::::..:::: :::::::: .:::::: XP_005 VPIAQLLPALLPAALTRVIMSSEQKSQHCKPEEGVEAQEEALGLVGAQAPTTEEQEAAVS 70 80 90 100 110 120 160 170 180 190 200 210 pF1KB6 SST-LNVGTLEELPAAESPSPPQSPQEESFSPTAMDAIFGSLSDEGSGSQEKEGPSTSPD ::. : :::::.::::: .:::::: : ::... .:::.:::.:::::::: XP_005 SSSPLVPGTLEEVPAAESAGPPQSPQGASALPTTISFTCWRQPNEGSSSQEEEGPSTSPD 130 140 150 160 170 180 220 230 240 250 260 270 pF1KB6 LIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEIFREASVC ::. .. : .:. .:.:.::::::.: :.:::::: :::::. :: :: .:: XP_005 ---AESLFREALSNKVDELAHFLLRKYRAKELVTKAEMLERVIKNYKRCFPVIFGKASES 190 200 210 220 230 280 290 300 310 320 330 pF1KB6 MQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIFMEGNCIP ....::::::::::.:..:.::: :.:::::. :.: .::.::::::::.: :::. XP_005 LKMIFGIDVKEVDPASNTYTLVTCLGLSYDGLLGNNQIFPKTGLLIIVLGTIAMEGDSAS 240 250 260 270 280 290 340 350 360 370 380 390 pF1KB6 EEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYEFLWGPRA :: .:: :..:::: :::: ..:::..::::.::::.:: ::::::..:: ::::::::: XP_005 EEEIWEELGVMGVYDGREHTVYGEPRKLLTQDWVQENYLEYRQVPGSNPARYEFLWGPRA 300 310 320 330 340 350 400 410 420 pF1KB6 HAETSKMKVLEYIANANGRDPTSYPSLYEDALREEGEGV :::: .::::... .:.: .:::: : :: :: ::: XP_005 LAETSYVKVLEHVVRVNARVRIAYPSLREAALLEEEEGV 360 370 380 390 >>NP_001011549 (OMIM: 300175) melanoma-associated antige (317 aa) initn: 1082 init1: 873 opt: 1243 Z-score: 1170.4 bits: 225.2 E(85289): 1.9e-58 Smith-Waterman score: 1243; 62.2% identity (80.3% similar) in 320 aa overlap (111-429:1-317) 90 100 110 120 130 140 pF1KB6 QRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEGLQAQEEDLGLVGAQA : ::.:::::::::..:::: :::::::: NP_001 MSSEQKSQHCKPEEGVEAQEEALGLVGAQA 10 20 30 150 160 170 180 190 pF1KB6 LQAEEQEAAFFSST-LNVGTLEELPAAESPSPPQSPQEESFSPTAMDAIFGSLSDEGSGS .:::::: ::. : :::::.::::: .:::::: : ::... .:::.: NP_001 PTTEEQEAAVSSSSPLVPGTLEEVPAAESAGPPQSPQGASALPTTISFTCWRQPNEGSSS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 QEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDY ::.:::::::: ::. .. : .:. .:.:.::::::.: :.:::::: :::::. NP_001 QEEEGPSTSPD---AESLFREALSNKVDELAHFLLRKYRAKELVTKAEMLERVIKNYKRC 100 110 120 130 140 260 270 280 290 300 310 pF1KB6 FPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVL :: :: .:: ....::::::::::.:..:.::: :.:::::. :.: .::.::::::: NP_001 FPVIFGKASESLKMIFGIDVKEVDPASNTYTLVTCLGLSYDGLLGNNQIFPKTGLLIIVL 150 160 170 180 190 200 320 330 340 350 360 370 pF1KB6 GVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDP :.: :::. :: .:: :..:::: :::: ..:::..::::.::::.:: ::::::..: NP_001 GTIAMEGDSASEEEIWEELGVMGVYDGREHTVYGEPRKLLTQDWVQENYLEYRQVPGSNP 210 220 230 240 250 260 380 390 400 410 420 pF1KB6 ACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALREEGEGV : ::::::::: :::: .::::... .:.: .:::: : :: :: ::: NP_001 ARYEFLWGPRALAETSYVKVLEHVVRVNARVRIAYPSLREAALLEEEEGV 270 280 290 300 310 >>NP_002353 (OMIM: 300175) melanoma-associated antigen 4 (317 aa) initn: 1082 init1: 873 opt: 1243 Z-score: 1170.4 bits: 225.2 E(85289): 1.9e-58 Smith-Waterman score: 1243; 62.2% identity (80.3% similar) in 320 aa overlap (111-429:1-317) 90 100 110 120 130 140 pF1KB6 QRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEGLQAQEEDLGLVGAQA : ::.:::::::::..:::: :::::::: NP_002 MSSEQKSQHCKPEEGVEAQEEALGLVGAQA 10 20 30 150 160 170 180 190 pF1KB6 LQAEEQEAAFFSST-LNVGTLEELPAAESPSPPQSPQEESFSPTAMDAIFGSLSDEGSGS .:::::: ::. : :::::.::::: .:::::: : ::... .:::.: NP_002 PTTEEQEAAVSSSSPLVPGTLEEVPAAESAGPPQSPQGASALPTTISFTCWRQPNEGSSS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 QEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDY ::.:::::::: ::. .. : .:. .:.:.::::::.: :.:::::: :::::. NP_002 QEEEGPSTSPD---AESLFREALSNKVDELAHFLLRKYRAKELVTKAEMLERVIKNYKRC 100 110 120 130 140 260 270 280 290 300 310 pF1KB6 FPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVL :: :: .:: ....::::::::::.:..:.::: :.:::::. :.: .::.::::::: NP_002 FPVIFGKASESLKMIFGIDVKEVDPASNTYTLVTCLGLSYDGLLGNNQIFPKTGLLIIVL 150 160 170 180 190 200 320 330 340 350 360 370 pF1KB6 GVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDP :.: :::. :: .:: :..:::: :::: ..:::..::::.::::.:: ::::::..: NP_002 GTIAMEGDSASEEEIWEELGVMGVYDGREHTVYGEPRKLLTQDWVQENYLEYRQVPGSNP 210 220 230 240 250 260 380 390 400 410 420 pF1KB6 ACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALREEGEGV : ::::::::: :::: .::::... .:.: .:::: : :: :: ::: NP_002 ARYEFLWGPRALAETSYVKVLEHVVRVNARVRIAYPSLREAALLEEEEGV 270 280 290 300 310 >>XP_005274735 (OMIM: 300175) PREDICTED: melanoma-associ (317 aa) initn: 1082 init1: 873 opt: 1243 Z-score: 1170.4 bits: 225.2 E(85289): 1.9e-58 Smith-Waterman score: 1243; 62.2% identity (80.3% similar) in 320 aa overlap (111-429:1-317) 90 100 110 120 130 140 pF1KB6 QRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEGLQAQEEDLGLVGAQA : ::.:::::::::..:::: :::::::: XP_005 MSSEQKSQHCKPEEGVEAQEEALGLVGAQA 10 20 30 150 160 170 180 190 pF1KB6 LQAEEQEAAFFSST-LNVGTLEELPAAESPSPPQSPQEESFSPTAMDAIFGSLSDEGSGS .:::::: ::. : :::::.::::: .:::::: : ::... .:::.: XP_005 PTTEEQEAAVSSSSPLVPGTLEEVPAAESAGPPQSPQGASALPTTISFTCWRQPNEGSSS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 QEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDY ::.:::::::: ::. .. : .:. .:.:.::::::.: :.:::::: :::::. XP_005 QEEEGPSTSPD---AESLFREALSNKVDELAHFLLRKYRAKELVTKAEMLERVIKNYKRC 100 110 120 130 140 260 270 280 290 300 310 pF1KB6 FPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVL :: :: .:: ....::::::::::.:..:.::: :.:::::. :.: .::.::::::: XP_005 FPVIFGKASESLKMIFGIDVKEVDPASNTYTLVTCLGLSYDGLLGNNQIFPKTGLLIIVL 150 160 170 180 190 200 320 330 340 350 360 370 pF1KB6 GVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDP :.: :::. :: .:: :..:::: :::: ..:::..::::.::::.:: ::::::..: XP_005 GTIAMEGDSASEEEIWEELGVMGVYDGREHTVYGEPRKLLTQDWVQENYLEYRQVPGSNP 210 220 230 240 250 260 380 390 400 410 420 pF1KB6 ACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALREEGEGV : ::::::::: :::: .::::... .:.: .:::: : :: :: ::: XP_005 ARYEFLWGPRALAETSYVKVLEHVVRVNARVRIAYPSLREAALLEEEEGV 270 280 290 300 310 >>XP_005274736 (OMIM: 300175) PREDICTED: melanoma-associ (317 aa) initn: 1082 init1: 873 opt: 1243 Z-score: 1170.4 bits: 225.2 E(85289): 1.9e-58 Smith-Waterman score: 1243; 62.2% identity (80.3% similar) in 320 aa overlap (111-429:1-317) 90 100 110 120 130 140 pF1KB6 QRITGGEQVLWGPITQIFPTVRPADLTRVIMPLEQRSQHCKPEEGLQAQEEDLGLVGAQA : ::.:::::::::..:::: :::::::: XP_005 MSSEQKSQHCKPEEGVEAQEEALGLVGAQA 10 20 30 150 160 170 180 190 pF1KB6 LQAEEQEAAFFSST-LNVGTLEELPAAESPSPPQSPQEESFSPTAMDAIFGSLSDEGSGS .:::::: ::. : :::::.::::: .:::::: : ::... .:::.: XP_005 PTTEEQEAAVSSSSPLVPGTLEEVPAAESAGPPQSPQGASALPTTISFTCWRQPNEGSSS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 QEKEGPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDY ::.:::::::: ::. .. : .:. .:.:.::::::.: :.:::::: :::::. XP_005 QEEEGPSTSPD---AESLFREALSNKVDELAHFLLRKYRAKELVTKAEMLERVIKNYKRC 100 110 120 130 140 260 270 280 290 300 310 pF1KB6 FPEIFREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVL :: :: .:: ....::::::::::.:..:.::: :.:::::. :.: .::.::::::: XP_005 FPVIFGKASESLKMIFGIDVKEVDPASNTYTLVTCLGLSYDGLLGNNQIFPKTGLLIIVL 150 160 170 180 190 200 320 330 340 350 360 370 pF1KB6 GVIFMEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDP :.: :::. :: .:: :..:::: :::: ..:::..::::.::::.:: ::::::..: XP_005 GTIAMEGDSASEEEIWEELGVMGVYDGREHTVYGEPRKLLTQDWVQENYLEYRQVPGSNP 210 220 230 240 250 260 380 390 400 410 420 pF1KB6 ACYEFLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALREEGEGV : ::::::::: :::: .::::... .:.: .:::: : :: :: ::: XP_005 ARYEFLWGPRALAETSYVKVLEHVVRVNARVRIAYPSLREAALLEEEEGV 270 280 290 300 310 429 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:25:23 2016 done: Sat Nov 5 11:25:24 2016 Total Scan time: 10.030 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]