FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6704, 128 aa 1>>>pF1KB6704 128 - 128 aa - 128 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1945+/-0.000685; mu= 10.8026+/- 0.041 mean_var=57.2232+/-11.660, 0's: 0 Z-trim(109.2): 84 B-trim: 390 in 1/50 Lambda= 0.169546 statistics sampled from 10623 (10724) to 10623 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.329), width: 16 Scan time: 1.620 The best scores are: opt bits E(32554) CCDS14608.1 SH2D1A gene_id:4068|Hs108|chrX ( 128) 852 216.0 5e-57 CCDS48162.1 SH2D1A gene_id:4068|Hs108|chrX ( 125) 818 207.7 1.5e-54 CCDS30928.1 SH2D1B gene_id:117157|Hs108|chr1 ( 132) 350 93.2 4.7e-20 CCDS77543.1 INPP5D gene_id:3635|Hs108|chr2 (1188) 289 78.7 1e-14 CCDS74672.1 INPP5D gene_id:3635|Hs108|chr2 (1189) 286 78.0 1.7e-14 CCDS8213.1 INPPL1 gene_id:3636|Hs108|chr11 (1258) 271 74.3 2.2e-13 >>CCDS14608.1 SH2D1A gene_id:4068|Hs108|chrX (128 aa) initn: 852 init1: 852 opt: 852 Z-score: 1137.4 bits: 216.0 E(32554): 5e-57 Smith-Waterman score: 852; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED 70 80 90 100 110 120 pF1KB6 PDVCLKAP :::::::: CCDS14 PDVCLKAP >>CCDS48162.1 SH2D1A gene_id:4068|Hs108|chrX (125 aa) initn: 746 init1: 746 opt: 818 Z-score: 1092.6 bits: 207.7 E(32554): 1.5e-54 Smith-Waterman score: 818; 97.7% identity (97.7% similar) in 128 aa overlap (1-128:1-125) 10 20 30 40 50 60 pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::: CCDS48 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQG---IRED 70 80 90 100 110 pF1KB6 PDVCLKAP :::::::: CCDS48 PDVCLKAP 120 >>CCDS30928.1 SH2D1B gene_id:117157|Hs108|chr1 (132 aa) initn: 376 init1: 346 opt: 350 Z-score: 473.5 bits: 93.2 E(32554): 4.7e-20 Smith-Waterman score: 350; 44.2% identity (72.6% similar) in 113 aa overlap (1-113:1-112) 10 20 30 40 50 60 pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE :: . :::..... : ::: :.::..:::::::.::: :::: ... .::::. . . CCDS30 MD-LPYYHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREK 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED : . .:: : :. : ..:.::: :.::.::.:. : :... : . .: CCDS30 HGYYRIQTAEGSPKQVFPSLKELISKFEKPNQGMVVHLLKPIKRTSPSLRWRGLKLELET 60 70 80 90 100 110 pF1KB6 PDVCLKAP CCDS30 FVNSNSDYVDVLP 120 130 >>CCDS77543.1 INPP5D gene_id:3635|Hs108|chr2 (1188 aa) initn: 286 init1: 286 opt: 289 Z-score: 377.8 bits: 78.7 E(32554): 1e-14 Smith-Waterman score: 289; 38.7% identity (68.9% similar) in 119 aa overlap (8-123:7-125) 10 20 30 40 50 60 pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE ::.:.: .:.:: :: :::.:.: :::. .: :::::.. .::::. .: CCDS77 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNE 10 20 30 40 50 70 80 90 100 110 pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV---EKKSSARSTQGTTGI ....... :: :.: :. .:: ..: ..:.: ::::: :. .. . : .. CCDS77 DDKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTESV 60 70 80 90 100 110 120 pF1KB6 REDPDVCLKAP :.. CCDS77 VSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEH 120 130 140 150 160 170 >>CCDS74672.1 INPP5D gene_id:3635|Hs108|chr2 (1189 aa) initn: 286 init1: 286 opt: 286 Z-score: 373.8 bits: 78.0 E(32554): 1.7e-14 Smith-Waterman score: 286; 45.3% identity (74.7% similar) in 95 aa overlap (8-102:7-101) 10 20 30 40 50 60 pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE ::.:.: .:.:: :: :::.:.: :::. .: :::::.. .::::. .: CCDS74 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED ....... :: :.: :. .:: ..: ..:.: ::::: CCDS74 DDKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTVES 60 70 80 90 100 110 pF1KB6 PDVCLKAP CCDS74 VVSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEE 120 130 140 150 160 170 >>CCDS8213.1 INPPL1 gene_id:3636|Hs108|chr11 (1258 aa) initn: 271 init1: 271 opt: 271 Z-score: 353.6 bits: 74.3 E(32554): 2.2e-13 Smith-Waterman score: 271; 43.3% identity (70.1% similar) in 97 aa overlap (7-103:22-118) 10 20 30 40 pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCV :: .:: ..:.:: .: :::.:.:::::: :.. ::: CCDS82 MASACGAPGPGGALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 LYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKK ::. ...:::. ...:. :: : :. . .::. . .:.::.: : ::: CCDS82 LYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGE 70 80 90 100 110 120 110 120 pF1KB6 SSARSTQGTTGIREDPDVCLKAP CCDS82 REPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAESAPNGLST 130 140 150 160 170 180 128 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:27:20 2016 done: Fri Nov 4 23:27:20 2016 Total Scan time: 1.620 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]