Result of FASTA (omim) for
pF1KB6704
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6704, 128 aa
1>>>pF1KB6704 128 - 128 aa - 128 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1153+/-0.000309; mu= 11.5014+/- 0.019
mean_var=64.5748+/-13.570, 0's: 0 Z-trim(115.6): 216 B-trim: 1130 in 2/51
Lambda= 0.159604
statistics sampled from 25969 (26242) to 25969 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.308), width: 16
Scan time: 4.700
The best scores are: opt bits E(85289)
NP_002342 (OMIM: 300490,308240) SH2 domain-contain ( 128) 852 204.4 4.3e-53
NP_001108409 (OMIM: 300490,308240) SH2 domain-cont ( 125) 818 196.5 9.5e-51
NP_444512 (OMIM: 608510) SH2 domain-containing pro ( 132) 350 88.8 2.7e-18
NP_005532 (OMIM: 601582) phosphatidylinositol 3,4, (1188) 289 75.3 2.8e-13
NP_001017915 (OMIM: 601582) phosphatidylinositol 3 (1189) 286 74.6 4.5e-13
XP_011543302 (OMIM: 258480,600829) PREDICTED: phos (1206) 271 71.2 5e-12
NP_001558 (OMIM: 258480,600829) phosphatidylinosit (1258) 271 71.2 5.2e-12
XP_011543301 (OMIM: 258480,600829) PREDICTED: phos (1258) 271 71.2 5.2e-12
XP_005274036 (OMIM: 258480,600829) PREDICTED: phos (1280) 271 71.2 5.2e-12
XP_005274035 (OMIM: 258480,600829) PREDICTED: phos (1280) 271 71.2 5.2e-12
NP_005148 (OMIM: 189980) tyrosine-protein kinase A (1130) 194 53.4 1e-06
NP_009297 (OMIM: 189980) tyrosine-protein kinase A (1149) 194 53.4 1e-06
NP_001129473 (OMIM: 164690) Abelson tyrosine-prote ( 542) 183 50.7 3.3e-06
NP_001161711 (OMIM: 164690) Abelson tyrosine-prote (1043) 183 50.9 5.6e-06
NP_001161710 (OMIM: 164690) Abelson tyrosine-prote (1058) 183 50.9 5.6e-06
NP_001129472 (OMIM: 164690) Abelson tyrosine-prote (1064) 183 50.9 5.7e-06
NP_001161709 (OMIM: 164690) Abelson tyrosine-prote (1079) 183 50.9 5.7e-06
XP_005245145 (OMIM: 164690) PREDICTED: Abelson tyr (1146) 183 50.9 6e-06
NP_001161708 (OMIM: 164690) Abelson tyrosine-prote (1161) 183 50.9 6.1e-06
NP_005149 (OMIM: 164690) Abelson tyrosine-protein (1167) 183 50.9 6.1e-06
NP_009298 (OMIM: 164690) Abelson tyrosine-protein (1182) 183 50.9 6.2e-06
XP_016856524 (OMIM: 164690) PREDICTED: Abelson tyr (1182) 183 50.9 6.2e-06
XP_016863512 (OMIM: 605768) PREDICTED: dual adapte ( 258) 164 46.1 3.7e-05
XP_016863513 (OMIM: 605768) PREDICTED: dual adapte ( 258) 164 46.1 3.7e-05
XP_011530144 (OMIM: 605768) PREDICTED: dual adapte ( 258) 164 46.1 3.7e-05
NP_001293080 (OMIM: 605768) dual adapter for phosp ( 263) 164 46.1 3.7e-05
XP_011530142 (OMIM: 605768) PREDICTED: dual adapte ( 267) 164 46.1 3.8e-05
NP_055210 (OMIM: 605768) dual adapter for phosphot ( 280) 164 46.1 3.9e-05
NP_001128524 (OMIM: 600085) tyrosine-protein kinas ( 612) 162 45.9 0.0001
NP_001167639 (OMIM: 600085) tyrosine-protein kinas ( 612) 162 45.9 0.0001
XP_005252204 (OMIM: 600085) PREDICTED: tyrosine-pr ( 635) 162 45.9 0.00011
NP_003168 (OMIM: 600085) tyrosine-protein kinase S ( 635) 162 45.9 0.00011
XP_011517248 (OMIM: 600085) PREDICTED: tyrosine-pr ( 635) 162 45.9 0.00011
NP_001167638 (OMIM: 600085) tyrosine-protein kinas ( 635) 162 45.9 0.00011
XP_011533958 (OMIM: 606573) PREDICTED: tyrosine-pr ( 392) 148 42.5 0.00067
XP_011533955 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 149 42.8 0.0007
XP_005266938 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 149 42.8 0.0007
XP_005266937 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 149 42.8 0.0007
NP_002022 (OMIM: 606573) tyrosine-protein kinase F ( 505) 149 42.8 0.0007
XP_011533957 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 149 42.8 0.0007
XP_011533956 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 149 42.8 0.0007
XP_005266939 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 149 42.8 0.0007
XP_016866134 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 149 42.8 0.0007
NP_004374 (OMIM: 124095) tyrosine-protein kinase C ( 450) 142 41.2 0.0019
NP_001120662 (OMIM: 124095) tyrosine-protein kinas ( 450) 142 41.2 0.0019
XP_005254222 (OMIM: 124095) PREDICTED: tyrosine-pr ( 450) 142 41.2 0.0019
XP_016877414 (OMIM: 124095) PREDICTED: tyrosine-pr ( 450) 142 41.2 0.0019
XP_016864932 (OMIM: 186973,613011) PREDICTED: tyro ( 495) 142 41.2 0.0021
NP_005537 (OMIM: 186973,613011) tyrosine-protein k ( 620) 142 41.3 0.0025
XP_011512049 (OMIM: 600058) PREDICTED: tyrosine-pr ( 508) 138 40.3 0.0041
>>NP_002342 (OMIM: 300490,308240) SH2 domain-containing (128 aa)
initn: 852 init1: 852 opt: 852 Z-score: 1074.2 bits: 204.4 E(85289): 4.3e-53
Smith-Waterman score: 852; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128)
10 20 30 40 50 60
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED
70 80 90 100 110 120
pF1KB6 PDVCLKAP
::::::::
NP_002 PDVCLKAP
>>NP_001108409 (OMIM: 300490,308240) SH2 domain-containi (125 aa)
initn: 746 init1: 746 opt: 818 Z-score: 1032.1 bits: 196.5 E(85289): 9.5e-51
Smith-Waterman score: 818; 97.7% identity (97.7% similar) in 128 aa overlap (1-128:1-125)
10 20 30 40 50 60
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQG---IRED
70 80 90 100 110
pF1KB6 PDVCLKAP
::::::::
NP_001 PDVCLKAP
120
>>NP_444512 (OMIM: 608510) SH2 domain-containing protein (132 aa)
initn: 376 init1: 346 opt: 350 Z-score: 449.3 bits: 88.8 E(85289): 2.7e-18
Smith-Waterman score: 350; 44.2% identity (72.6% similar) in 113 aa overlap (1-113:1-112)
10 20 30 40 50 60
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
:: . :::..... : ::: :.::..:::::::.::: :::: ... .::::. . .
NP_444 MD-LPYYHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREK
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED
: . .:: : :. : ..:.::: :.::.::.:. : :... : . .:
NP_444 HGYYRIQTAEGSPKQVFPSLKELISKFEKPNQGMVVHLLKPIKRTSPSLRWRGLKLELET
60 70 80 90 100 110
pF1KB6 PDVCLKAP
NP_444 FVNSNSDYVDVLP
120 130
>>NP_005532 (OMIM: 601582) phosphatidylinositol 3,4,5-tr (1188 aa)
initn: 286 init1: 286 opt: 289 Z-score: 359.4 bits: 75.3 E(85289): 2.8e-13
Smith-Waterman score: 289; 38.7% identity (68.9% similar) in 119 aa overlap (8-123:7-125)
10 20 30 40 50 60
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
::.:.: .:.:: :: :::.:.: :::. .: :::::.. .::::. .:
NP_005 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNE
10 20 30 40 50
70 80 90 100 110
pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV---EKKSSARSTQGTTGI
....... :: :.: :. .:: ..: ..:.: ::::: :. .. . : ..
NP_005 DDKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTESV
60 70 80 90 100 110
120
pF1KB6 REDPDVCLKAP
:..
NP_005 VSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEH
120 130 140 150 160 170
>>NP_001017915 (OMIM: 601582) phosphatidylinositol 3,4,5 (1189 aa)
initn: 286 init1: 286 opt: 286 Z-score: 355.7 bits: 74.6 E(85289): 4.5e-13
Smith-Waterman score: 286; 45.3% identity (74.7% similar) in 95 aa overlap (8-102:7-101)
10 20 30 40 50 60
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
::.:.: .:.:: :: :::.:.: :::. .: :::::.. .::::. .:
NP_001 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNE
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED
....... :: :.: :. .:: ..: ..:.: :::::
NP_001 DDKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTVES
60 70 80 90 100 110
pF1KB6 PDVCLKAP
NP_001 VVSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEE
120 130 140 150 160 170
>>XP_011543302 (OMIM: 258480,600829) PREDICTED: phosphat (1206 aa)
initn: 271 init1: 271 opt: 271 Z-score: 337.0 bits: 71.2 E(85289): 5e-12
Smith-Waterman score: 271; 43.3% identity (70.1% similar) in 97 aa overlap (7-103:22-118)
10 20 30 40
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCV
:: .:: ..:.:: .: :::.:.:::::: :.. :::
XP_011 MASACGAPGPGGALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 LYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKK
::. ...:::. ...:. :: : :. . .::. . .:.::.: : :::
XP_011 LYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGE
70 80 90 100 110 120
110 120
pF1KB6 SSARSTQGTTGIREDPDVCLKAP
XP_011 REPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAERDGAEVLG
130 140 150 160 170 180
>>NP_001558 (OMIM: 258480,600829) phosphatidylinositol 3 (1258 aa)
initn: 271 init1: 271 opt: 271 Z-score: 336.7 bits: 71.2 E(85289): 5.2e-12
Smith-Waterman score: 271; 43.3% identity (70.1% similar) in 97 aa overlap (7-103:22-118)
10 20 30 40
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCV
:: .:: ..:.:: .: :::.:.:::::: :.. :::
NP_001 MASACGAPGPGGALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 LYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKK
::. ...:::. ...:. :: : :. . .::. . .:.::.: : :::
NP_001 LYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGE
70 80 90 100 110 120
110 120
pF1KB6 SSARSTQGTTGIREDPDVCLKAP
NP_001 REPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAESAPNGLST
130 140 150 160 170 180
>>XP_011543301 (OMIM: 258480,600829) PREDICTED: phosphat (1258 aa)
initn: 271 init1: 271 opt: 271 Z-score: 336.7 bits: 71.2 E(85289): 5.2e-12
Smith-Waterman score: 271; 43.3% identity (70.1% similar) in 97 aa overlap (7-103:22-118)
10 20 30 40
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCV
:: .:: ..:.:: .: :::.:.:::::: :.. :::
XP_011 MASACGAPGPGGALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 LYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKK
::. ...:::. ...:. :: : :. . .::. . .:.::.: : :::
XP_011 LYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGE
70 80 90 100 110 120
110 120
pF1KB6 SSARSTQGTTGIREDPDVCLKAP
XP_011 REPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAESAPNGLST
130 140 150 160 170 180
>>XP_005274036 (OMIM: 258480,600829) PREDICTED: phosphat (1280 aa)
initn: 271 init1: 271 opt: 271 Z-score: 336.6 bits: 71.2 E(85289): 5.2e-12
Smith-Waterman score: 271; 43.3% identity (70.1% similar) in 97 aa overlap (7-103:22-118)
10 20 30 40
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCV
:: .:: ..:.:: .: :::.:.:::::: :.. :::
XP_005 MASACGAPGPGGALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 LYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKK
::. ...:::. ...:. :: : :. . .::. . .:.::.: : :::
XP_005 LYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGE
70 80 90 100 110 120
110 120
pF1KB6 SSARSTQGTTGIREDPDVCLKAP
XP_005 REPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAERDGAEVLG
130 140 150 160 170 180
>>XP_005274035 (OMIM: 258480,600829) PREDICTED: phosphat (1280 aa)
initn: 271 init1: 271 opt: 271 Z-score: 336.6 bits: 71.2 E(85289): 5.2e-12
Smith-Waterman score: 271; 43.3% identity (70.1% similar) in 97 aa overlap (7-103:22-118)
10 20 30 40
pF1KB6 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCV
:: .:: ..:.:: .: :::.:.:::::: :.. :::
XP_005 MASACGAPGPGGALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 LYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKK
::. ...:::. ...:. :: : :. . .::. . .:.::.: : :::
XP_005 LYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGE
70 80 90 100 110 120
110 120
pF1KB6 SSARSTQGTTGIREDPDVCLKAP
XP_005 REPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAERDGAEVLG
130 140 150 160 170 180
128 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:27:20 2016 done: Fri Nov 4 23:27:21 2016
Total Scan time: 4.700 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]