FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6705, 76 aa 1>>>pF1KB6705 76 - 76 aa - 76 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.3066+/-0.000279; mu= 11.7701+/- 0.017 mean_var=43.3152+/- 8.527, 0's: 0 Z-trim(117.6): 56 B-trim: 97 in 1/48 Lambda= 0.194874 statistics sampled from 29617 (29674) to 29617 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.348), width: 16 Scan time: 3.630 The best scores are: opt bits E(85289) NP_003087 (OMIM: 603542) small nuclear ribonucleop ( 76) 499 146.6 3.7e-36 NP_001304095 (OMIM: 603542) small nuclear ribonucl ( 75) 482 141.8 1e-34 NP_001304096 (OMIM: 603542) small nuclear ribonucl ( 68) 423 125.2 9e-30 NP_001304098 (OMIM: 603542) small nuclear ribonucl ( 64) 415 122.9 4.1e-29 NP_001304097 (OMIM: 603542) small nuclear ribonucl ( 64) 415 122.9 4.1e-29 XP_016860263 (OMIM: 603542) PREDICTED: small nucle ( 96) 409 121.3 1.8e-28 NP_001304094 (OMIM: 603542) small nuclear ribonucl ( 96) 409 121.3 1.8e-28 NP_001304100 (OMIM: 603542) small nuclear ribonucl ( 58) 376 111.9 7.5e-26 NP_057283 (OMIM: 607287) U6 snRNA-associated Sm-li ( 103) 182 57.5 3.2e-09 XP_016863162 (OMIM: 607286) PREDICTED: U6 snRNA-as ( 80) 137 44.8 1.7e-05 NP_009011 (OMIM: 607286) U6 snRNA-associated Sm-li ( 80) 137 44.8 1.7e-05 XP_016863161 (OMIM: 607286) PREDICTED: U6 snRNA-as ( 80) 137 44.8 1.7e-05 NP_057284 (OMIM: 607288) LSM8 homolog, U6 small nu ( 96) 132 43.5 5.1e-05 NP_055277 (OMIM: 607281) U6 snRNA-associated Sm-li ( 133) 128 42.4 0.00015 XP_016882358 (OMIM: 607287) PREDICTED: U6 snRNA-as ( 160) 123 41.1 0.00045 NP_001315567 (OMIM: 128260,615059) small nuclear r ( 79) 111 37.5 0.0026 NP_001291393 (OMIM: 128260,615059) small nuclear r ( 84) 111 37.5 0.0027 NP_001315566 (OMIM: 128260,615059) small nuclear r ( 90) 111 37.5 0.0029 NP_003085 (OMIM: 128260,615059) small nuclear ribo ( 92) 111 37.6 0.003 NP_036454 (OMIM: 607285) U6 snRNA-associated Sm-li ( 91) 110 37.3 0.0036 NP_003086 (OMIM: 603541) small nuclear ribonucleop ( 86) 106 36.1 0.0074 >>NP_003087 (OMIM: 603542) small nuclear ribonucleoprote (76 aa) initn: 499 init1: 499 opt: 499 Z-score: 770.2 bits: 146.6 E(85289): 3.7e-36 Smith-Waterman score: 499; 100.0% identity (100.0% similar) in 76 aa overlap (1-76:1-76) 10 20 30 40 50 60 pF1KB6 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV 10 20 30 40 50 60 70 pF1KB6 VIRGNSIIMLEALERV :::::::::::::::: NP_003 VIRGNSIIMLEALERV 70 >>NP_001304095 (OMIM: 603542) small nuclear ribonucleopr (75 aa) initn: 410 init1: 410 opt: 482 Z-score: 744.5 bits: 141.8 E(85289): 1e-34 Smith-Waterman score: 482; 98.7% identity (98.7% similar) in 76 aa overlap (1-76:1-75) 10 20 30 40 50 60 pF1KB6 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV 10 20 30 40 50 60 70 pF1KB6 VIRGNSIIMLEALERV ::::::::::::::: NP_001 -IRGNSIIMLEALERV 70 >>NP_001304096 (OMIM: 603542) small nuclear ribonucleopr (68 aa) initn: 423 init1: 423 opt: 423 Z-score: 655.5 bits: 125.2 E(85289): 9e-30 Smith-Waterman score: 423; 100.0% identity (100.0% similar) in 65 aa overlap (12-76:4-68) 10 20 30 40 50 60 pF1KB6 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MCLFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV 10 20 30 40 50 70 pF1KB6 VIRGNSIIMLEALERV :::::::::::::::: NP_001 VIRGNSIIMLEALERV 60 >>NP_001304098 (OMIM: 603542) small nuclear ribonucleopr (64 aa) initn: 415 init1: 415 opt: 415 Z-score: 643.7 bits: 122.9 E(85289): 4.1e-29 Smith-Waterman score: 415; 100.0% identity (100.0% similar) in 64 aa overlap (13-76:1-64) 10 20 30 40 50 60 pF1KB6 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV 10 20 30 40 70 pF1KB6 VIRGNSIIMLEALERV :::::::::::::::: NP_001 VIRGNSIIMLEALERV 50 60 >>NP_001304097 (OMIM: 603542) small nuclear ribonucleopr (64 aa) initn: 415 init1: 415 opt: 415 Z-score: 643.7 bits: 122.9 E(85289): 4.1e-29 Smith-Waterman score: 415; 100.0% identity (100.0% similar) in 64 aa overlap (13-76:1-64) 10 20 30 40 50 60 pF1KB6 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV 10 20 30 40 70 pF1KB6 VIRGNSIIMLEALERV :::::::::::::::: NP_001 VIRGNSIIMLEALERV 50 60 >>XP_016860263 (OMIM: 603542) PREDICTED: small nuclear r (96 aa) initn: 406 init1: 406 opt: 409 Z-score: 631.9 bits: 121.3 E(85289): 1.8e-28 Smith-Waterman score: 409; 82.9% identity (89.5% similar) in 76 aa overlap (1-76:1-76) 10 20 30 40 50 60 pF1KB6 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV 10 20 30 40 50 60 70 pF1KB6 VIRGNSIIMLEALERV :. . . :..: XP_016 DNIPNKAVSPKFLKKVNQKGQLTFSKLLSIKTSKEW 70 80 90 >>NP_001304094 (OMIM: 603542) small nuclear ribonucleopr (96 aa) initn: 406 init1: 406 opt: 409 Z-score: 631.9 bits: 121.3 E(85289): 1.8e-28 Smith-Waterman score: 409; 82.9% identity (89.5% similar) in 76 aa overlap (1-76:1-76) 10 20 30 40 50 60 pF1KB6 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV 10 20 30 40 50 60 70 pF1KB6 VIRGNSIIMLEALERV :. . . :..: NP_001 DNIPNKAVSPKFLKKVNQKGQLTFSKLLSIKTSKEW 70 80 90 >>NP_001304100 (OMIM: 603542) small nuclear ribonucleopr (58 aa) initn: 376 init1: 376 opt: 376 Z-score: 585.1 bits: 111.9 E(85289): 7.5e-26 Smith-Waterman score: 376; 98.3% identity (100.0% similar) in 58 aa overlap (19-76:1-58) 10 20 30 40 50 60 pF1KB6 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV .::::::::::::::::::::::::::::::::::::::::: NP_001 MKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMV 10 20 30 40 70 pF1KB6 VIRGNSIIMLEALERV :::::::::::::::: NP_001 VIRGNSIIMLEALERV 50 >>NP_057283 (OMIM: 607287) U6 snRNA-associated Sm-like p (103 aa) initn: 164 init1: 137 opt: 182 Z-score: 286.6 bits: 57.5 E(85289): 3.2e-09 Smith-Waterman score: 182; 39.4% identity (74.6% similar) in 71 aa overlap (8-70:14-84) 10 20 30 40 50 pF1KB6 MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVE-MATSGQ .:.:..:: . .:..:::...:::.::::..:::.: .: : . NP_057 MADKEKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDD 10 20 30 40 50 60 60 70 pF1KB6 Q-------NNIGMVVIRGNSIIMLEALERV : ..:.:: ::.:.... NP_057 QYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFIQQQDA 70 80 90 100 >>XP_016863162 (OMIM: 607286) PREDICTED: U6 snRNA-associ (80 aa) initn: 152 init1: 133 opt: 137 Z-score: 219.8 bits: 44.8 E(85289): 1.7e-05 Smith-Waterman score: 137; 27.6% identity (69.7% similar) in 76 aa overlap (1-75:3-78) 10 20 30 40 50 pF1KB6 MSKAHPPE-LKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNI . : : . ::... . . .:::.: .:.: .: .::..... :.... .:. XP_016 MSLRKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKY 10 20 30 40 50 60 60 70 pF1KB6 GMVVIRGNSIIMLEALERV : . ::::..... . .: XP_016 GDAFIRGNNVLYISTQKRRM 70 80 76 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:28:43 2016 done: Fri Nov 4 23:28:43 2016 Total Scan time: 3.630 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]