FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6706, 129 aa 1>>>pF1KB6706 129 - 129 aa - 129 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8983+/-0.000328; mu= 13.1013+/- 0.020 mean_var=57.5439+/-11.368, 0's: 0 Z-trim(115.4): 7 B-trim: 1002 in 1/53 Lambda= 0.169073 statistics sampled from 25816 (25823) to 25816 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.303), width: 16 Scan time: 4.930 The best scores are: opt bits E(85289) NP_003173 (OMIM: 162320) protachykinin-1 isoform b ( 129) 856 216.4 1e-56 NP_054702 (OMIM: 162320) protachykinin-1 isoform a ( 111) 642 164.1 4.8e-41 NP_054704 (OMIM: 162320) protachykinin-1 isoform d ( 96) 497 128.7 1.9e-30 NP_054703 (OMIM: 162320) protachykinin-1 isoform g ( 114) 497 128.8 2.2e-30 >>NP_003173 (OMIM: 162320) protachykinin-1 isoform beta (129 aa) initn: 856 init1: 856 opt: 856 Z-score: 1139.1 bits: 216.4 E(85289): 1e-56 Smith-Waterman score: 856; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:1-129) 10 20 30 40 50 60 pF1KB6 MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERS 70 80 90 100 110 120 pF1KB6 AMQNYERRR ::::::::: NP_003 AMQNYERRR >>NP_054702 (OMIM: 162320) protachykinin-1 isoform alpha (111 aa) initn: 642 init1: 642 opt: 642 Z-score: 858.0 bits: 164.1 E(85289): 4.8e-41 Smith-Waterman score: 689; 85.3% identity (86.0% similar) in 129 aa overlap (1-129:1-111) 10 20 30 40 50 60 pF1KB6 MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERS :::::::::::::::::::::::::::::::::::: .::::: NP_054 PQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHK------------------MAYERS 70 80 90 100 pF1KB6 AMQNYERRR ::::::::: NP_054 AMQNYERRR 110 >>NP_054704 (OMIM: 162320) protachykinin-1 isoform delta (96 aa) initn: 577 init1: 497 opt: 497 Z-score: 667.7 bits: 128.7 E(85289): 1.9e-30 Smith-Waterman score: 563; 73.6% identity (74.4% similar) in 129 aa overlap (1-129:1-96) 10 20 30 40 50 60 pF1KB6 MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERS ::::::::::::: :::::::: .::::: NP_054 PQQFFGLMGKRDA---------------GHGQISHK------------------MAYERS 70 80 pF1KB6 AMQNYERRR ::::::::: NP_054 AMQNYERRR 90 >>NP_054703 (OMIM: 162320) protachykinin-1 isoform gamma (114 aa) initn: 756 init1: 497 opt: 497 Z-score: 666.6 bits: 128.8 E(85289): 2.2e-30 Smith-Waterman score: 730; 88.4% identity (88.4% similar) in 129 aa overlap (1-129:1-114) 10 20 30 40 50 60 pF1KB6 MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERS ::::::::::::: :::::::::::::::::::::::::::::::: NP_054 PQQFFGLMGKRDA---------------GHGQISHKRHKTDSFVGLMGKRALNSVAYERS 70 80 90 100 pF1KB6 AMQNYERRR ::::::::: NP_054 AMQNYERRR 110 129 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:19:07 2016 done: Sat Nov 5 08:19:08 2016 Total Scan time: 4.930 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]