Result of FASTA (omim) for pF1KB6709
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6709, 79 aa
  1>>>pF1KB6709 79 - 79 aa - 79 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9337+/-0.000283; mu= 9.1421+/- 0.018
 mean_var=55.0524+/-11.089, 0's: 0 Z-trim(118.4): 90  B-trim: 267 in 2/48
 Lambda= 0.172857
 statistics sampled from 31155 (31253) to 31155 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.366), width:  16
 Scan time:  3.960

The best scores are:                                      opt bits E(85289)
NP_003113 (OMIM: 167790,167800,608189) serine prot (  79)  539 141.6 1.2e-34
NP_066937 (OMIM: 605753) serine protease inhibitor (  84)  180 52.1 1.1e-07
NP_001258649 (OMIM: 605753) serine protease inhibi ( 119)  174 50.7 4.3e-07
NP_001258647 (OMIM: 605753) serine protease inhibi ( 134)  174 50.7 4.8e-07
NP_995313 (OMIM: 615868) serine protease inhibitor (  80)  170 49.6 6.2e-07
NP_001182219 (OMIM: 615868) serine protease inhibi (  80)  170 49.6 6.2e-07
NP_001035523 (OMIM: 613511) serine protease inhibi (  86)  167 48.9 1.1e-06
XP_011532707 (OMIM: 605753) PREDICTED: serine prot ( 186)  169 49.6 1.5e-06
NP_006837 (OMIM: 147050,256500,605010) serine prot (1064)  162 48.2 2.2e-05
XP_011535853 (OMIM: 147050,256500,605010) PREDICTE (1066)  162 48.2 2.2e-05
NP_001121170 (OMIM: 147050,256500,605010) serine p (1094)  162 48.2 2.3e-05
NP_055286 (OMIM: 613929) serine protease inhibitor (  86)  147 43.9 3.5e-05
XP_016865198 (OMIM: 613511) PREDICTED: serine prot ( 107)  145 43.5   6e-05
NP_001121171 (OMIM: 147050,256500,605010) serine p ( 916)  155 46.4 6.6e-05
XP_011539731 (OMIM: 103320,615120) PREDICTED: agri (2004)  153 46.1 0.00018
NP_940978 (OMIM: 103320,615120) agrin isoform 2 pr (2045)  153 46.1 0.00019
XP_005244806 (OMIM: 103320,615120) PREDICTED: agri (2049)  153 46.1 0.00019
NP_001292204 (OMIM: 103320,615120) agrin isoform 1 (2068)  153 46.1 0.00019
NP_001035218 (OMIM: 615205) serine protease inhibi (  94)  136 41.2 0.00025
NP_003683 (OMIM: 603421) tomoregulin-1 precursor [ ( 380)  142 43.0  0.0003
NP_001292074 (OMIM: 605734) tomoregulin-2 isoform  ( 175)  138 41.8  0.0003
XP_016859229 (OMIM: 605734) PREDICTED: tomoregulin ( 266)  138 41.9 0.00044
XP_016859228 (OMIM: 605734) PREDICTED: tomoregulin ( 337)  138 42.0 0.00053
NP_001292063 (OMIM: 605734) tomoregulin-2 isoform  ( 346)  138 42.0 0.00054
XP_011509192 (OMIM: 605734) PREDICTED: tomoregulin ( 365)  138 42.0 0.00057
NP_057276 (OMIM: 605734) tomoregulin-2 isoform 1 p ( 374)  138 42.0 0.00058


>>NP_003113 (OMIM: 167790,167800,608189) serine protease  (79 aa)
 initn: 539 init1: 539 opt: 539  Z-score: 742.9  bits: 141.6 E(85289): 1.2e-34
Smith-Waterman score: 539; 100.0% identity (100.0% similar) in 79 aa overlap (1-79:1-79)

               10        20        30        40        50        60
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVL
               10        20        30        40        50        60

               70         
pF1KB6 CFENRKRQTSILIQKSGPC
       :::::::::::::::::::
NP_003 CFENRKRQTSILIQKSGPC
               70         

>>NP_066937 (OMIM: 605753) serine protease inhibitor Kaz  (84 aa)
 initn: 184 init1: 167 opt: 180  Z-score: 258.6  bits: 52.1 E(85289): 1.1e-07
Smith-Waterman score: 180; 38.7% identity (65.3% similar) in 75 aa overlap (6-79:10-84)

                   10        20        30         40        50     
pF1KB6     MKVTGIFLLSALALLSLSGNTGADSLGREAKCYN-ELNGCTKIYDPVCGTDGNTYP
                ..::..    ::  . :  :  :  .: . .: :: . ..::::.: .:: 
NP_066 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPGCPRHFNPVCGSDMSTYA
               10        20        30        40        50        60

          60        70         
pF1KB6 NECVLCFENRKRQTSILIQKSGPC
       :::.::.. :.   .: : ..:::
NP_066 NECTLCMKIREGGHNIKIIRNGPC
               70        80    

>>NP_001258649 (OMIM: 605753) serine protease inhibitor   (119 aa)
 initn: 184 init1: 167 opt: 174  Z-score: 248.2  bits: 50.7 E(85289): 4.3e-07
Smith-Waterman score: 174; 41.5% identity (66.2% similar) in 65 aa overlap (16-79:55-119)

                              10        20        30         40    
pF1KB6                MKVTGIFLLSALALLSLSGNTGADSLGREAKCYN-ELNGCTKIYD
                                     ::  . :  :  :  .: . .: :: . ..
NP_001 PGERGPPEKSGFGSQTGGGPCPAPGGLGDASLIPQFGLFSKYRTPNCSQYRLPGCPRHFN
           30        40        50        60        70        80    

           50        60        70         
pF1KB6 PVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPC
       ::::.: .:: :::.::.. :.   .: : ..:::
NP_001 PVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
           90       100       110         

>>NP_001258647 (OMIM: 605753) serine protease inhibitor   (134 aa)
 initn: 184 init1: 167 opt: 174  Z-score: 247.4  bits: 50.7 E(85289): 4.8e-07
Smith-Waterman score: 174; 41.5% identity (66.2% similar) in 65 aa overlap (16-79:70-134)

                              10        20        30         40    
pF1KB6                MKVTGIFLLSALALLSLSGNTGADSLGREAKCYN-ELNGCTKIYD
                                     ::  . :  :  :  .: . .: :: . ..
NP_001 TGGGPCPAPGGLGDGTRAPVTGGSPEDLPASLIPQFGLFSKYRTPNCSQYRLPGCPRHFN
      40        50        60        70        80        90         

           50        60        70         
pF1KB6 PVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPC
       ::::.: .:: :::.::.. :.   .: : ..:::
NP_001 PVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
     100       110       120       130    

>>NP_995313 (OMIM: 615868) serine protease inhibitor Kaz  (80 aa)
 initn: 166 init1: 108 opt: 170  Z-score: 245.5  bits: 49.6 E(85289): 6.2e-07
Smith-Waterman score: 170; 37.3% identity (65.1% similar) in 83 aa overlap (1-79:1-80)

               10        20        30            40        50      
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNG----CTKIYDPVCGTDGNTYPN
       ::..:.::: .:::. .   ::. : : .. : .:..     ::.  .: ::.::.:: :
NP_995 MKLSGMFLLLSLALFCFL--TGVFSQGGQVDC-GEFQDPKVYCTRESNPHCGSDGQTYGN
               10          20        30         40        50       

         60        70         
pF1KB6 ECVLCFENRKRQTSILIQKSGPC
       .:..:    :   .: ... : :
NP_995 KCAFCKAIVKSGGKISLKHPGKC
        60        70        80

>>NP_001182219 (OMIM: 615868) serine protease inhibitor   (80 aa)
 initn: 166 init1: 108 opt: 170  Z-score: 245.5  bits: 49.6 E(85289): 6.2e-07
Smith-Waterman score: 170; 37.3% identity (65.1% similar) in 83 aa overlap (1-79:1-80)

               10        20        30            40        50      
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNG----CTKIYDPVCGTDGNTYPN
       ::..:.::: .:::. .   ::. : : .. : .:..     ::.  .: ::.::.:: :
NP_001 MKLSGMFLLLSLALFCFL--TGVFSQGGQVDC-GEFQDPKVYCTRESNPHCGSDGQTYGN
               10          20        30         40        50       

         60        70         
pF1KB6 ECVLCFENRKRQTSILIQKSGPC
       .:..:    :   .: ... : :
NP_001 KCAFCKAIVKSGGKISLKHPGKC
        60        70        80

>>NP_001035523 (OMIM: 613511) serine protease inhibitor   (86 aa)
 initn: 127 init1: 116 opt: 167  Z-score: 241.0  bits: 48.9 E(85289): 1.1e-06
Smith-Waterman score: 167; 32.6% identity (62.8% similar) in 86 aa overlap (1-79:1-86)

               10        20        30               40        50   
pF1KB6 MKVTGIFLLSALALLSLSGNTGADSLGREAKC--YNELNG-----CTKIYDPVCGTDGNT
       :..:.: :: ::.: .. .   : .  . . :  :..:       : ..:::.::.::.:
NP_001 MRATAIVLLLALTLATMFSIECAKQTKQMVDCSHYKKLPPGQQRFCHHMYDPICGSDGKT
               10        20        30        40        50        60

            60        70         
pF1KB6 YPNECVLCFENRKRQTSILIQKSGPC
       : :.: .: . .: . .. . . : :
NP_001 YKNDCFFCSKVKKTDGTLKFVHFGKC
               70        80      

>>XP_011532707 (OMIM: 605753) PREDICTED: serine protease  (186 aa)
 initn: 167 init1: 167 opt: 169  Z-score: 238.5  bits: 49.6 E(85289): 1.5e-06
Smith-Waterman score: 169; 41.8% identity (70.9% similar) in 55 aa overlap (26-79:132-186)

                    10        20        30         40        50    
pF1KB6      MKVTGIFLLSALALLSLSGNTGADSLGREAKCYN-ELNGCTKIYDPVCGTDGNTY
                                     :  . .: . .: :: . ..::::.: .::
XP_011 AQVTDRRGKTAGAGGGWRCRCCAWRCCSWQLPSQPNCSQYRLPGCPRHFNPVCGSDMSTY
             110       120       130       140       150       160 

           60        70         
pF1KB6 PNECVLCFENRKRQTSILIQKSGPC
        :::.::.. :.   .: : ..:::
XP_011 ANECTLCMKIREGGHNIKIIRNGPC
             170       180      

>>NP_006837 (OMIM: 147050,256500,605010) serine protease  (1064 aa)
 initn: 367 init1: 150 opt: 162  Z-score: 217.5  bits: 48.2 E(85289): 2.2e-05
Smith-Waterman score: 162; 53.7% identity (68.3% similar) in 41 aa overlap (39-79:1006-1046)

       10        20        30        40        50        60        
pF1KB6 LSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQ
                                     : :   :::: ::.:: : :.:: ::  ::
NP_006 SQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQ
         980       990      1000      1010      1020      1030     

       70                           
pF1KB6 TSILIQKSGPC                  
       :.  :...: :                  
NP_006 TNTHIRSTGKCEESSTPGTTAASMPPSDE
        1040      1050      1060    

>--
 initn: 231 init1: 136 opt: 155  Z-score: 208.1  bits: 46.4 E(85289): 7.5e-05
Smith-Waterman score: 155; 48.8% identity (70.7% similar) in 41 aa overlap (39-79:111-151)

       10        20        30        40        50        60        
pF1KB6 LSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQ
                                     :   :. ::::::.:: :.:.:: :: :  
NP_006 RHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTG
               90       100       110       120       130       140

       70                                                          
pF1KB6 TSILIQKSGPC                                                 
       ..: ... : :                                                 
NP_006 SQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAEL
              150       160       170       180       190       200

>>XP_011535853 (OMIM: 147050,256500,605010) PREDICTED: s  (1066 aa)
 initn: 367 init1: 150 opt: 162  Z-score: 217.5  bits: 48.2 E(85289): 2.2e-05
Smith-Waterman score: 162; 53.7% identity (68.3% similar) in 41 aa overlap (39-79:1008-1048)

       10        20        30        40        50        60        
pF1KB6 LSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQ
                                     : :   :::: ::.:: : :.:: ::  ::
XP_011 SQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQ
       980       990      1000      1010      1020      1030       

       70                           
pF1KB6 TSILIQKSGPC                  
       :.  :...: :                  
XP_011 TNTHIRSTGKCEESSTPGTTAASMPPSDE
      1040      1050      1060      

>--
 initn: 231 init1: 136 opt: 155  Z-score: 208.1  bits: 46.4 E(85289): 7.5e-05
Smith-Waterman score: 155; 48.8% identity (70.7% similar) in 41 aa overlap (39-79:83-123)

       10        20        30        40        50        60        
pF1KB6 LSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQ
                                     :   :. ::::::.:: :.:.:: :: :  
XP_011 RHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTG
             60        70        80        90       100       110  

       70                                                          
pF1KB6 TSILIQKSGPC                                                 
       ..: ... : :                                                 
XP_011 SQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAEL
            120       130       140       150       160       170  




79 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 23:30:03 2016 done: Fri Nov  4 23:30:04 2016
 Total Scan time:  3.960 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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